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Specialty: Neurology
Condition: Disability
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Total 4114 results found since Jan 2013.
Post-stroke Headache
AbstractPurpose of ReviewStroke is a major health concern and a leading cause of long-term disability. Persistent post-stroke headache (PPSH) is a common complication of stroke yet little is known about its specific characteristics or optimal management. The purpose of this review is to discuss the epidemiology, presentation, and hypothesized pathophysiology of PPSH. Acute and preventive treatment options, as well as specific concerns regarding triptans and the newer CGRP antagonists, will be discussed in detail as well.Recent FindingsThe 2018 International Classification of Headache Disorders, 3rd edition (ICHD-3) was the...
Source: Current Pain and Headache Reports - September 7, 2023 Category: Neurology Source Type: research
A modified murine photothrombotic stroke model: a minimally invasive and reproducible cortical and sub-cortical infarct volume and long-term deficits
In conclusion, this modified model helps to understand stroke pathogenesis and minimize the animals' numbers which help to increase the scientific and statistical potential in pre-clinical studies.PMID:37656197 | DOI:10.1007/s00221-023-06696-5
Source: Brain Research - September 1, 2023 Category: Neurology Authors: Mohd Salman Saifudeen Ismael Tauheed Ishrat Source Type: research
Secondary neurodegeneration following Stroke: what can blood biomarkers tell us?
Stroke is one of the leading causes of death and the primary source of disability in adults, resulting in neuronal necrosis of ischemic areas, and in possible secondary degeneration of regions surrounding or distant to the initial damaged area. Secondary neurodegeneration (SNDG) following stroke has been shown to have different pathogenetic origins including inflammation, neurovascular response and cytotoxicity, but can be associated also to regenerative processes. Aside from focal neuronal loss, ipsilateral and contralateral effects distal to the lesion site, disruptions of global functional connectivity and a transcallos...
Source: Frontiers in Neurology - September 1, 2023 Category: Neurology Source Type: research
Oxidative stress and early mortality in acute ischemic stroke: A prospective cohort study
CONCLUSION: MDA serum level was significantly higher in non-survivors than in survivors patients, so MDA could be used as a predictor for early mortality and short-term outcome of cases with AIS.PMID:37652662 | DOI:10.1080/01616412.2023.2252284
Source: Neurological Research - August 31, 2023 Category: Neurology Authors: Eman A Elhamrawy Heba Shoman Hayam Abdel-Tawab Eshak I Bahbah Rasha Sobhy Elattar Naema R Hussein Marwa Sonbol Asmaa AbdElghany Elsheikh Source Type: research
Lower 25-hydroxyvitamin D is associated with severer white matter hyperintensity and cognitive function in patients with non-disabling ischemic cerebrovascular events
Vascular cognitive impairment (VCI) is the second most common type of cognitive impairment, referring to the entire spectrum of cognitive impairment contributed by cerebrovascular pathology1. Due to the progressively higher incidence of stroke and cerebrovascular diseases, VCI, including post-stroke cognitive impairment are the leading causes of disability epidemic worldwide2-3. White matter lesions, manifested as white matter hyperintensities (WMH) on T2-weighted magnetic resonance imaging (MRI) scans, are one of the most common pathological characteristics of VCI4.
Source: Journal of Stroke and Cerebrovascular Diseases - August 31, 2023 Category: Neurology Authors: Zhengsheng Gu, Xu Sun, Chenghao Wu, Binghan Li, Jingjing Chen, Weisen Wang, Xin Gao, Yuhao Tan, Bin Li, Ge Yin, Yawen Xu, Chenrui Song, Bingying Du, Xiaoying Bi Source Type: research
Strengthening stroke prevention and awareness in the Philippines: a conceptual framework
This article focuses on stroke prevention and awareness in the Philippines, a country grappling with high stroke incidence and limited healthcare resources. The two-pronged approach presented by the authors aims to address the challenges of stroke care by combining community-based prevention and targeted public awareness campaigns. The community-based stroke prevention component involves personalized risk factor assessments and tailored interventions conducted at local health centers. By identifying modifiable risk factors such as hypertension, diabetes, smoking, and elevated cholesterol levels, healthcare professionals ca...
Source: Frontiers in Neurology - August 31, 2023 Category: Neurology Source Type: research
Post-stroke pneumonia: Factors associated with readmission within 90 days of stroke discharge
Stroke is the fifth leading cause of death and a leading cause of disability within the United States.1,2 On average, a stroke occurs every 40 seconds and accounts for approximately 1 in every 19 deaths.2 The prevalence of stroke is projected to increase by 20.5% from 2012 to 2030.2 Post-stroke complications are prevalent; infection occurs among 30% of acute cases.3 Pneumonia is one of the most common post-stroke infections and is associated with increased morbidity.4,5 Moreover, pneumonia is recognized as an independent risk factor for stroke-related mortality.
Source: Journal of Stroke and Cerebrovascular Diseases - August 21, 2023 Category: Neurology Authors: Tiffany Bouddhara, LeighAnn Persondek, Elizabeth Ablah, Hayrettin Okut, Liuqiang Lu, James Walker Source Type: research
Risk of suicide among stroke survivors in the United States
Stroke is the largest cause of disability and the 5th leading cause of death in the United States. Suicide is the 12th leading cause of death in the United States. However, little is known about the risk of suicide among people with a prior stroke.
Source: Journal of Stroke and Cerebrovascular Diseases - August 19, 2023 Category: Neurology Authors: Ben Grobman, Neeharika Kothapalli, Arian Mansur, Christine Y Lu Source Type: research
Surgery for Malignant Acute Ischemic Stroke: A Narrative Review of the Knowns and Unknowns
Semin Neurol 2023; 43: 370-387 DOI: 10.1055/s-0043-1771208Malignant acute ischemic stroke (AIS) is characterized by acute neurological deterioration caused by progressive space-occupying brain edema, often occurring in the first hours to days after symptom onset. Without any treatment, the result is often fatal. Despite advances in treatment for AIS, up to 80% of patients with a large hemispheric stroke or cerebellar stroke are at risk of poor outcome. Decompressive surgery can be life-saving in a subgroup of patients with malignant AIS, but uncertainties exist on patient selection, predictors of malignant infarction, peri...
Source: Seminars in Neurology - August 18, 2023 Category: Neurology Authors: Krishnan, Kailash Hollingworth, Milo Nguyen, Thanh N. Kumaria, Ashwin Kirkman, Matthew A. Basu, Surajit Tolias, Christos Bath, Philip M. Sprigg, Nikola Tags: Review Article Source Type: research
The potential link between acromegaly and risk of acute ischemic stroke in patients with pituitary adenoma: a new perspective
AbstractAcromegaly is an endocrine disorder due to the excess production of growth hormone (GH) from the anterior pituitary gland after closed epiphyseal growth plates. Acromegaly is mainly caused by benign GH-secreting pituitary adenoma. Acute ischemic stroke (AIS) is one of the most common cardiovascular complications. It ranks second after ischemic heart disease (IHD) as a cause of disability and death in high-income countries globally. Thus, this review aimed to elucidate the possible link between acromegaly and the development of AIS. The local effects of acromegaly in the development of AIS are related to the develop...
Source: Acta Neurologica Belgica - August 16, 2023 Category: Neurology Source Type: research
Stroke in the Developing Brain: Neurophysiological Implications of Stroke Timing, Location, and Comorbid Factors
Pediatric stroke, which is unique in that it represents a static insult to a developing brain, often leads to long-term neurological disability. Neuroplasticity in infants and children influences neurophysiologic recovery patterns after stroke therefore outcomes depend on several factors including timing and location of stroke and the presence of comorbid conditions.
Source: Pediatric Neurology - August 11, 2023 Category: Neurology Authors: Nayo M. Hill, Laura A. Malone, Lisa R. Sun Source Type: research
Train-your-brain program to reduce depression, anxiety, and stress in stroke survivors: a pilot community-based cognitive intervention study
DiscussionThe TYB program provided group support and validation, resulting in improved mood and reduced stress among stroke survivors. Cultural collectivism played a significant role in fostering group cohesion. However, the program’s limited focus on caregivers and timing of assessments during the December holidays may have affected the outcomes. The TYB program demonstrated feasibility and potential effectiveness in alleviating psychological distress and enhancing cognitive function among stroke survivors. Future research should explore long-term effects, larger sample sizes, and non-English-speaking populations to enh...
Source: Frontiers in Neurology - August 10, 2023 Category: Neurology Source Type: research
Importance of microRNAs by mRNA-microRNA integration analysis in acute ischemic stroke patients
Acute ischemic stroke is common, and severe forms of the condition are becoming notably widespread due to the aging population.1 Patients with severe ischemic stroke are at high risk of mortality or disability due to neurological deficits, requiring long-term care; neurological deficits are typically associated with increased medical costs.1, 2 Recently, the treatment of severe hyperacute ischemic stroke has been established due to the introduction of recombinant tissue plasminogen activators3,4 and endovascular treatment,5 –7 but only selected population can benefit from these treatments.
Source: Journal of Stroke and Cerebrovascular Diseases - August 8, 2023 Category: Neurology Authors: Hideaki Kanki, Hisatake Matsumoto, Yuki Togami, Daisuke Okuzaki, Hiroshi Ogura, Tsutomu Sasaki, Hideki Mochizuki Source Type: research
