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Specialty: Neurology
Condition: Disability
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Total 4114 results found since Jan 2013.
Knowledge and awareness of stroke and associated factors in the Saudi general population: a cross-sectional study
ConclusionOur study revealed that participants have good knowledge about stroke. Nonetheless, further efforts are required to raise awareness and educate the public to optimize and ensure better treatment outcomes.
Source: Frontiers in Neurology - September 21, 2023 Category: Neurology Source Type: research
Protein kinase D2 confers neuroprotection by promoting AKT and CREB activation in ischemic stroke
In this study, we found that PKD2 expression and activity were significantly upregulated in the ipsilateral side of the brain after transient focal cerebral ischemia, which coincides with the upregulation of PKD2 in primary neurons in response to in vitro ischemia, implying a potential role of PKD2 in neuronal survival in ischemic stroke. Using kinase-dead PKD2 knock-in (PKD2-KI) mice, we examined whether loss of PKD2 activity affected stroke outcomes in mice subjected to 1 h of transient middle cerebral artery occlusion (tMCAO) and 24 h of reperfusion. Our data demonstrated that PKD2-KI mice exhibited larger infarction vo...
Source: Neurobiology of Disease - September 20, 2023 Category: Neurology Authors: Jaclyn A Connelly Xuejing Zhang Yuzhou Chen Yapeng Chao Yejie Shi Tija C Jacob Q Jane Wang Source Type: research
Persian version of the Chalder Fatigue Questionnaire and Multidimensional Fatigue Symptom Inventory-Short Form: psychometric properties in Iranian chronic stroke survivors
CONCLUSIONS: The results of this study showed that the CFQ and MFSI-SF have high reliability and validity for chronic stroke survivors.PMID:37723098 | DOI:10.1080/10749357.2023.2175421
Source: Topics in Stroke Rehabilitation - September 18, 2023 Category: Neurology Authors: Soheila Fallah Ghorban Taghizadeh Zahra Parnain Moslem Cheraghifard Parvaneh Taghavi Azar Sharabiani Mahin Yousefi Mohammad Taghi Joghataei Ali Gholizade Source Type: research
Rhein attenuates cerebral ischemia-reperfusion injury via inhibition of ferroptosis through NRF2/SLC7A11/GPX4 pathway
CONCLUSION: Rhein attenuates cerebral I/R injury by inhibiting ferroptosis via the NRF2/SLC7A11/GPX4 axis, highlighting its potential as a therapeutic agent for ischemic stroke.PMID:37714424 | DOI:10.1016/j.expneurol.2023.114541
Source: Experimental Neurology - September 15, 2023 Category: Neurology Authors: Hua Liu Tian-Ai Zhang Wen-Yue Zhang Si-Rui Huang Yue Hu Jia Sun Source Type: research
A rehabilitative approach beyond the acute stroke event: a scoping review about functional recovery perspectives in the chronic hemiplegic patient
ConclusionThe literature analyzed invites us to reflect respect to neurorehabilitation approach to the patient with chronic stroke sequelae often considered to have as its objective the maintenance of the present motor function and contain disability: instead, the review reports how, even in chronicity, the patient always reports margins of statistically and clinically significant improvement. The chronic stroke rehabilitation over 6 months has been proved effective in obtaining recovery in different settings.
Source: Frontiers in Neurology - September 15, 2023 Category: Neurology Source Type: research
Corticospinal tract: a new hope for the treatment of post-stroke spasticity
AbstractStroke is the third leading cause of death and disability worldwide. Post-stroke spasticity (PSS) is the most common complication of stroke but represents only one of the many manifestations of upper motor neuron syndrome. As an upper motor neuron, the corticospinal tract (CST) is the only direct descending motor pathway that innervates the spinal motor neurons and is closely related to the recovery of limb function in patients with PSS. Therefore, promoting axonal remodeling in the CST may help identify new therapeutic strategies for PSS. In this review, we outline the pathological mechanisms of PSS, specifically ...
Source: Acta Neurologica Belgica - September 13, 2023 Category: Neurology Source Type: research
Clinical narratives as a predictor for prognosticating functional outcomes after intracerebral hemorrhage
This study aimed to investigate whether clinical narratives can improve the performance for predicting functional outcomes after ICH.
Source: Journal of the Neurological Sciences - September 12, 2023 Category: Neurology Authors: Ling-Chien Hung, Ying-Ying Su, Jui-Ming Sun, Wan-Ting Huang, Sheng-Feng Sung Source Type: research
Sensory deficits of the paretic and non-paretic upper limbs relate with the motor recovery of the poststroke subjects
CONCLUSION: In stroke, sensory deficits relate weakly with the recovery of the paretic upper limb and can predict recovery potential of the paretic upper limb.PMID:37690032 | DOI:10.1080/10749357.2023.2253629
Source: Topics in Stroke Rehabilitation - September 10, 2023 Category: Neurology Authors: Kamal Narayan Arya Shanta Pandian Akshay Kumar Joshi Neera Chaudhary G G Agarwal Syed Shafi Ahmed Source Type: research
