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Specialty: Neurology
Condition: Disability

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Total 4114 results found since Jan 2013.

Clinical examination of spatial neglect and other disorders of spatial cognition
Nervenarzt. 2023 Aug 3. doi: 10.1007/s00115-023-01525-0. Online ahead of print.ABSTRACTNeglect occurring after stroke, neoplasms or degenerative processes can lead to considerable disability in everyday life as can other disorders of spatial orientation. Therefore, a dedicated examination and early diagnostic classification are obligatory. Behavioral tests are helpful in this respect, enabling the clinician to obtain an initial overview of the existing deficits even at the patient's bedside. The clinical (bedside) examination of spatial neglect as well as the corresponding differential diagnostic procedure for the clarific...
Source: Der Nervenarzt - August 3, 2023 Category: Neurology Authors: Britta Stammler Hannah Rosenzopf Lisa R öhrig Stefan Smaczny Tamara Matuz Thomas Schenk Hans-Otto Karnath Source Type: research

Sarcopenia in acute ischemic stroke patients and patients with Parkinson ’s disease
Background: Sarcopenia is a condition characterized by a progressive generalized loss of skeletal muscle mass and strength. The most common nutritional problem that predisposes an ischemic stroke (IS) is sarcopenia. In patients with Parkinson's disease (PD), sarcopenia may represent the common downstream pathway that, from motor and non-motor symptoms leads to the progressive loss of resilience, frailty, and disability.
Source: Parkinsonism and Related Disorders - August 1, 2023 Category: Neurology Authors: S. Mandjikoska, G. Horvat Pinteri ć Source Type: research

Age-Associated Resilience Against Ischemic Injury in Mice Exposed to Transient Middle Cerebral Artery Occlusion
AbstractIschemic stroke is the leading cause of death and disability. Although stroke mainly affects aged individuals, animal research is mostly one on young rodents. Here, we examined the development of ischemic injury in young (9 –12-week-old) and adult (72-week-old) C57BL/6 and BALB/c mice exposed to 30 min of intraluminal middle cerebral artery occlusion (MCAo). Post-ischemic reperfusion did not differ between young and adult mice. Ischemic injury assessed by infarct area and blood-brain barrier (BBB) integrity assessed by IgG extravasation analysis was smaller in adult compared with young mice. Microvascular viabili...
Source: Molecular Neurobiology - August 1, 2023 Category: Neurology Source Type: research

A novel digital approach for post-stroke cognitive deficits: a pilot study
CONCLUSIONS: These results suggest that combining digital PA with cognitive training using serious games may be added in clinical settings for cognitive rehabilitation of stroke patients, with beneficial effects extending in promoting independency in activities of daily living and reduction of psychiatric symptoms.PMID:37522228 | DOI:10.3233/RNN-231305
Source: Restorative Neurology and Neuroscience - July 31, 2023 Category: Neurology Authors: Massimiliano Oliveri Sergio Bagnato Silvia Rizzo Emilia Imbornone Andreina Giustiniani Angela Catania Patrizia Turriziani Source Type: research

Burden and attributable risk factors of ischemic stroke in China from 1990 to 2019: an analysis from the Global Burden of Disease Study 2019
ConclusionOur study revealed that great changes have occurred in burden and attributable risk factors of ischemic stroke in China in the past three decades. Distinct sex-specific differences are observed in burden and attributable risk factors.
Source: Frontiers in Neurology - July 26, 2023 Category: Neurology Source Type: research

Long-term behavioural alterations in mice following transient cerebral ischemia
The objective of this study was to clarify whether and to what extent mouse behaviour was altered during a 6 months period after cerebral stroke. Experimental stroke was induced in mice by intraluminal filament insertion into the middle cerebral artery (fMCAo). Neurological deficits, recovery rate, motor performance, and circadian activity were evaluated following ischemia. We observed severe neurological deficits, motor impairments, and delay in the recovery rate of mice during the first 14 days after fMCAo. Aberrant circadian activity and distorted space map were seen in fMCAo mice starting one month after ischemia, simi...
Source: Brain Research - July 22, 2023 Category: Neurology Authors: Zane Dzirkale Vladimirs Pilipenko Barbara Pijet Linda Klimaviciusa Jolanta Upite Karolina Protokowicz Leszek Kaczmarek Baiba Jansone Source Type: research