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Total 354 results found since Jan 2013.

Increased frequency of multiple sclerosis among patients with bullous pemphigoid: a population ‐based cohort study on comorbidities anchored around the diagnosis of bullous pemphigoid
ConclusionsWe discovered a significantly increased frequency of MS among patients with BP. At the time of diagnosis, patients with BP had an excessive number of comorbidities and an increased mortality rate over the following years.
Source: British Journal of Dermatology - April 10, 2017 Category: Dermatology Authors: L. Kibsgaard, M. Rasmussen, A. Lamberg, M. Deleuran, A.B. Olesen, C. Vestergaard Tags: Epidemiology Source Type: research

Evaluation of the correlation between severity of acquired idiopathic generalized anhidrosis and quality of life scores
The objective of this study was to evaluate the correlation between AIGA severity and QOL. Study subjects comprised 44 patients diagnosed with AIGA at three registered institutions. AIGA severity assessment was conducted and the Dermatology Life Quality Index (DLQI) questionnaire was administered. Correlations between AIGA severity and DLQI, as well as severity by DLQI subscale, were assessed. We found a positive correlation between total score of AIGA severity criteria and DLQI total scores (R = 0.720, P = 0.001). The impairment increased with the increase in AIGA severity (P < 0.01). In relation to the DLQI subscales,...
Source: The Journal of Dermatology - March 22, 2017 Category: Dermatology Authors: Takichi Munetsugu, Tomoko Fujimoto, Takahiro Satoh, Yoshihiko Nakazato, Yuichiro Ohshima, Masato Asahina, Hiroo Yokozeki Tags: Original Article Source Type: research

Prognostic factors for mortality in patients with bullous pemphigoid: a meta-analysis
This study indicated that BP patients with older age, circulating antibodies, dementia, and stroke are at greater risk of mortality. Clinicians should be aware of this association and utilize this information in patient education and treatment process.
Source: Archives of Dermatological Research - March 18, 2017 Category: Dermatology Source Type: research

Neurodegenerative disorders, bullous pemphigoid and psoriasis: a comparative study in ethnic Poles indicates that Parkinson's disease is more relevant to bullous pemphigoid.
CONCLUSIONS: Thus, regarding population aging and increasing incidence and prevalence of BP corresponding with that phenomenon in various ethnicities, it appears justified to expand studies of a possible immunopathogenic relationship, appearing to be PD-related, between BP and ND. PMID: 28261030 [PubMed - in process]
Source: Advances in Dermatology and Allergology - March 8, 2017 Category: Dermatology Tags: Postepy Dermatol Alergol Source Type: research

Increased frequency of multiple sclerosis among bullous pemphigoid patients. A population-based cohort study on comorbidities anchored around the diagnosis of bullous pemphigoid.
CONCLUSIONS: We discovered a significantly increased frequency of MS among BP patients. At the time of diagnosis, BP patients had an excessive number of comorbidities and an increased mortality rate over the years to follow. This article is protected by copyright. All rights reserved. PMID: 28235244 [PubMed - as supplied by publisher]
Source: The British Journal of Dermatology - February 23, 2017 Category: Dermatology Authors: Kibsgaard L, Rasmussen M, Lamberg A, Deleuran M, Olesen AB, Vestergaard C Tags: Br J Dermatol Source Type: research

Increased frequency of multiple sclerosis among bullous pemphigoid patients. A population ‐based cohort study on comorbidities anchored around the diagnosis of bullous pemphigoid
ConclusionsWe discovered a significantly increased frequency of MS among BP patients. At the time of diagnosis, BP patients had an excessive number of comorbidities and an increased mortality rate over the years to follow.This article is protected by copyright. All rights reserved.
Source: British Journal of Dermatology - February 23, 2017 Category: Dermatology Authors: L. Kibsgaard, M. Rasmussen, A. Lamberg, M. Deleuran, A.B. Olesen, C. Vestergaard Tags: Original Article Source Type: research

Psoriasis and cardiovascular events: updating the evidence
In conclusion, this updated meta-analysis confirmed that patients with psoriasis have an increased risk of CVD, especially those with severe psoriasis.
Source: Archives of Dermatological Research - February 16, 2017 Category: Dermatology Source Type: research

Epidemiology and cardiovascular comorbidities in patients with psoriasis: A Korean nationwide population ‐based cohort study
In conclusion, the prevalence of psoriasis, while within the range of previous reports, tended to increase over time. Patients with PsA had higher burdens of specific comorbid diseases than those with PsV, especially at a comparatively early age.
Source: The Journal of Dermatology - February 12, 2017 Category: Dermatology Authors: Eui Hyun Oh, Young Suck Ro, Jeong Eun Kim Tags: Original Article Source Type: research

Morbidity and Causes of Death in Patients with Cutaneous T-cell Lymphoma in Finland.
Abstract Cutaneous T-cell lymphomas (CTCL), especially mycosis fungoides, can be considered as a state of longstanding low-grade systemic inflammation. Many studies have focused on secondary cancers with CTCL, but information about comorbidities is limited. A total of 144 patients with CTCL at Helsinki University Central Hospital during 2005 to 2015 were studied to determine associated comorbidities and causes of death in this cohort. Compared with an age-standardized control population, the prevalence of type 2 diabetes mellitus was increased among patients with CTCL with no link to obesity. Patients with CTCL ha...
Source: Acta Dermato-Venereologica - February 7, 2017 Category: Dermatology Authors: Väkevä L, Lipsanen T, Sintonen H, Ranki A Tags: Acta Derm Venereol Source Type: research

Neurological diseases and bullous pemphigoid: A case & #8211;control study in Iranian patients
Conclusions: Neurological diseases in general, and stroke and dementia in particular, were significantly associated with bullous pemphigoid in our study.
Source: Indian Journal of Dermatology, Venereology and Leprology - February 2, 2017 Category: Dermatology Authors: Maryam Daneshpazhooh Javad Khorassani Kamran Balighi Narges Ghandi Hamidreza Mahmoudi Hamidreza Tohidinik Shahin Hamzelou Cheyda Chams-Davatchi Source Type: research

Impact of adalimumab treatment on cardiovascular risk biomarkers in psoriasis: Results of a pilot study
Abstract Psoriasis is a chronic systemic immune‐mediated inflammatory dermatosis associated with several comorbidities. Psoriasis patients are at increased risk of developing cardiovascular diseases (CVD), namely, coronary heart disease, stroke or peripheral vascular disease, and psoriasis seems to be an independent cardiovascular risk factor. Antipsoriatic systemic therapy, especially anti‐tumor necrosis factor (TNF)‐α, seems to exert a beneficial effect on these comorbidities. The purpose of this study was: (i) to measure the level of cardiovascular serum markers in psoriasis patients in comparison with healthy vo...
Source: The Journal of Dermatology - October 23, 2016 Category: Dermatology Authors: Spyridon Gkalpakiotis, Monika Arenbergerova, Petra Gkalpakioti, Jana Potockova, Petr Arenberger, Pavel Kraml Tags: Original Article Source Type: research

Risk of incident chronic kidney disease and end-stage renal disease in people with psoriasis: A nationwide population-based cohort study
Background: Psoriasis has been associated with various comorbidities related to chronic inflammation, for example myocardial infarction and stroke. However, the relation between psoriasis and renal disease is less characterised. Objective: To assess the associations of psoriasis with chronic kidney disease (CKD) and end-stage renal disease (ESRD).
Source: Journal of Dermatological Science - September 29, 2016 Category: Dermatology Authors: Ching-Chi Chi, Jui Wang, Yu-Fen Chen, Shu-Hui Wang, Tao-Hsin Tung Tags: P06-01[C06-04] Source Type: research

Scanning electron microscopy of the adhesion of Treponema pallidum subspecies pallidum (Nichol strain) to human brain microvascular endothelial cells in vitro
This article is protected by copyright. All rights reserved.
Source: Journal of the European Academy of Dermatology and Venereology - September 28, 2016 Category: Dermatology Authors: Fan Wu, Jing ‐Ping Zhang, Qian‐Qiu Wang Tags: Letter to Editor Source Type: research

Bullous pemphigoid and its association with neurological diseases: a systematic review and meta ‐analysis
This study aimed to investigate if patients with BP have significantly higher risks for neurological disorders, compared to controls. A comprehensive search was performed using MEDLINE, EMBASE and Cochrane library databases. Case–control and cohort studies that assessed the relationship between BP and neurological diseases were included. DerSimonian and Laird random‐effects models were utilized to calculate the pooled relative risks (RRs). Publication bias was evaluated qualitatively by constructing a funnel plot and quantitatively by conducting Egger's test. Fourteen studies, with 23 369 BP cases and 128 697 controls ...
Source: Journal of the European Academy of Dermatology and Venereology - September 6, 2016 Category: Dermatology Authors: Y.C. Lai, Y.W. Yew, W.C. Lambert Tags: Review Article Source Type: research

Clinical Analysis and Management of Acquired Idiopathic Generalized Anhidrosis.
Authors: Satoh T Abstract Acquired idiopathic generalized anhidrosis (AIGA) is a sweating disorder characterized by inadequate sweating in response to heat stimuli such as high temperature, humidity, and physical exercise. Patients exhibit widespread nonsegmental hypohidrosis/anhidrosis without any apparent cause, but the palms, soles, and axillae are rarely affected. Heat stroke readily develops due to increased body temperature. AIGA commonly affects young males. Approximately 30-60% of patients show complications of cholinergic urticaria, also known as idiopathic pure sudomotor failure or hypohidrotic cholinergi...
Source: Current Problems in Dermatology - September 3, 2016 Category: Dermatology Tags: Curr Probl Dermatol Source Type: research