Filtered By:
Specialty: Dermatology

This page shows you your search results in order of date. This is page number 17.

Order by Relevance | Date

Total 354 results found since Jan 2013.

Sturge Weber syndrome: A rare clinical presentation with bilateral port wine stain and leptomenigeal angiomatosis
Introduction: Sturge-Weber syndrome (SWS) is a neurocutaneous syndrome that has a heterogeneous spectrum of manifestations, characterized by facial port-wine stain (PWS) within the trigeminal nerve distribution, ipsilateral leptomeningeal angiomatosis, glaucoma, seizures, stroke-like episodes, hemiparesis, and mental retardation. The diagnosis is based on clinical presentation and cranial imaging features. Treatment is a challenge and multidisciplinary approach is required to control ophthalmic, neurologic and dermatologic manifestations.
Source: Journal of the American Academy of Dermatology - August 2, 2018 Category: Dermatology Source Type: research

The bacteria stroke: Leclercia adecarboxylata folliculitis in a healthy swimmer —an emerging aquatic pathogen?
A 12-year-old healthy boy presented with a 2-month painful acneiform eruption. On exam erythematous follicular papules and pustules were scattered over bilateral shoulders and back. These surfaces were moderately tender to light palpation; the patient even complained that clothing in contact with his skin elicited pain. Doxycycline 75 mg po qd × 10 days was prescribed to cover common Staphylococcus aureus folliculitis. Due to the atypical presentation of significant pain, a bacterial culture was collected.
Source: Journal of the American Academy of Dermatology - August 2, 2018 Category: Dermatology Source Type: research

Prevalence of smoking, alcohol consumption and metabolic syndrome in patients with psoriasis
Conclusions: Our results indicate that MBS is a risk factor for psoriasis patients with advanced age. The relationship between disease severity and obesity, diabetes, and smoking in psoriasis patients indicates that the patients should be informed about the potential metabolic risks and receive therapies for behavioral changes besides anti-psoriatic treatment in order to minimize these risks.
Source: Anais Brasileiros de Dermatologia - May 3, 2018 Category: Dermatology Source Type: research

096 Demographic and serologic features differentiate bullous pemphigoid with and without preceding neurologic disease
This study aimed to identify features that may differentiate BP patients with and without neurologic disease. 105 patients with BP were enrolled in this study: 75 control BP patients with no neurologic disease (CON), 10 patients with BP and a prior diagnosis of Parkinson ’s disease (BP+PD), 11 BP with dementia patients (BP+DEM), and 9 BP with stroke (BP+STR).
Source: Journal of Investigative Dermatology - April 27, 2018 Category: Dermatology Authors: A. Miller, K. Messingham, N. Narayanan, S. Connell, J. Fairley Tags: Adaptive and Auto-Immunity Source Type: research

830 Fabry rat skin findings demonstrate potential roles of inflammation and lipoatrophy in Fabry disease
Fabry disease is an X-linked lysosomal disease caused by α-galactosidase A deficiency. Patients experience distal extremity pain and often develop renal failure, cardiomyopathy, and stroke. Dermatological manifestations include sweating abnormalities and angiokeratomas. To gain a better understanding of disease mechanisms, we generated a Fabry rat model using CRISPR/Cas9 technology and confirmed the absence of α-galactosidase A activity in tissues. Wild type (WT) and Fabry rats were indistinguishable at young ages (weaning-6 months), but aging (9 months+) Fabry rats developed an unkempt appearance, alopecia, and xeroderma.
Source: Journal of Investigative Dermatology - April 27, 2018 Category: Dermatology Authors: J.J. Miller, O. Sokumbi, P.E. North, N.M. Dahms Tags: Genetic Disease, Gene Regulation, and Gene Therapy Source Type: research

755 Mosaic RAS/MAPK variants cause sporadic vascular malformations which respond to targeted therapy
Sporadic vascular malformations (VMs) are complex congenital anomalies of blood vessels which lead to disfigurement, overgrowth, stroke, pain and/or life-threatening bleeding, depending on the vessel size and the body site. Therapeutic options are severely limited and multi-disciplinary management remains challenging. To investigate the pathogenesis of 160 sporadic intracranial and extracranial VMs in which known genetic causes had been excluded, sequencing of affected tissue DNA was undertaken using next generation sequencing optimised for detection of low mutant allele frequency.
Source: Journal of Investigative Dermatology - April 27, 2018 Category: Dermatology Authors: S. Polubothu, L. Al-Olabi, K. Dowsett, K. Andrews, P. Stadnik, R. Knox, W. Baird, M. Glover, C. Moss, A. Thomas, L. Biesecker, R. Semple, E. Patton, V. Kinsler Tags: Genetic Disease, Gene Regulation, and Gene Therapy Source Type: research

Psoriasis as a cardiovascular risk factor: updates and algorithmic approach.
Authors: Cozzani E, Rosa G, Burlando M, Parodi A Abstract Although psoriasis is predominantly a chronic inflammatory skin disorder, it has been known to be associated with cardiovascular disease. Patients with psoriasis, particularly with moderate to severe forms, present an increased rate of cardiovascular mortality, myocardial infarction and stroke. However the pathophysiology of the relationship between psoriasis and cardiovascular risk and comorbidities has not yet completely known. Chronic inflammation may be considered a solid link between psoriasis and related cardiovascular events. Several cytokines and inf...
Source: Giornale Italiano di Dermatologia e Venereologia - April 24, 2018 Category: Dermatology Tags: G Ital Dermatol Venereol Source Type: research

096 Demographic and serologic features differentiate bullous pemphigoid with and without preceding neurologic disease
This study aimed to identify features that may differentiate BP patients with and without neurologic disease. 105 patients with BP were enrolled in this study: 75 control BP patients with no neurologic disease (CON), 10 patients with BP and a prior diagnosis of Parkinson ’s disease (BP+PD), 11 BP with dementia patients (BP+DEM), and 9 BP with stroke (BP+STR).
Source: Journal of Investigative Dermatology - April 19, 2018 Category: Dermatology Authors: A. Miller, K. Messingham, N. Narayanan, S. Connell, J. Fairley Tags: Adaptive and Auto-Immunity Source Type: research

830 Fabry rat skin findings demonstrate potential roles of inflammation and lipoatrophy in Fabry disease
Fabry disease is an X-linked lysosomal disease caused by α-galactosidase A deficiency. Patients experience distal extremity pain and often develop renal failure, cardiomyopathy, and stroke. Dermatological manifestations include sweating abnormalities and angiokeratomas. To gain a better understanding of disease mechanisms, we generated a Fabry rat model using CRISPR/Cas9 technology and confirmed the absence of α-galactosidase A activity in tissues. Wild type (WT) and Fabry rats were indistinguishable at young ages (weaning-6 months), but aging (9 months+) Fabry rats developed an unkempt appearance, alopecia, and xeroderma.
Source: Journal of Investigative Dermatology - April 19, 2018 Category: Dermatology Authors: J.J. Miller, O. Sokumbi, P.E. North, N.M. Dahms Tags: Genetic Disease, Gene Regulation, and Gene Therapy Source Type: research

755 Mosaic RAS/MAPK variants cause sporadic vascular malformations which respond to targeted therapy
Sporadic vascular malformations (VMs) are complex congenital anomalies of blood vessels which lead to disfigurement, overgrowth, stroke, pain and/or life-threatening bleeding, depending on the vessel size and the body site. Therapeutic options are severely limited and multi-disciplinary management remains challenging. To investigate the pathogenesis of 160 sporadic intracranial and extracranial VMs in which known genetic causes had been excluded, sequencing of affected tissue DNA was undertaken using next generation sequencing optimised for detection of low mutant allele frequency.
Source: Journal of Investigative Dermatology - April 19, 2018 Category: Dermatology Authors: S. Polubothu, L. Al-Olabi, K. Dowsett, K. Andrews, P. Stadnik, R. Knox, W. Baird, M. Glover, C. Moss, A. Thomas, L. Biesecker, R. Semple, E. Patton, V. Kinsler Tags: Genetic Disease, Gene Regulation, and Gene Therapy Source Type: research

Blood vessel occlusion with erythrocyte aggregates causes burn injury progression: microvasculature dilation as a possible therapy
This article is protected by copyright. All rights reserved.
Source: Experimental Dermatology - February 25, 2018 Category: Dermatology Authors: Richard A. F. Clark, Justine Fenner, Arielle Sasson, Steve A. McClain, Adam J. Singer, Marcia G. Tonnesen Tags: Viewpoint Source Type: research

Mortality and Comorbidity Profiles of Patients with Bullous Pemphigoid in Korea.
Conclusion: The mortality rate of patients with BP is higher than that of the general Korean population. Korean patients with BP are more likely to have dementia, Parkinson's disease, diabetes, and stroke. Risk factors for increased 5-year mortality include old age at the time of diagnosis and medical comorbidities, especially cardiac disease and renal disease. PMID: 29386827 [PubMed]
Source: Annals of Dermatology - February 2, 2018 Category: Dermatology Tags: Ann Dermatol Source Type: research

Hidradenitis suppurativa is associated with myocardial infarction, but not stroke or peripheral arterial disease of the lower extremities
British Journal of Dermatology, EarlyView.
Source: British Journal of Dermatology - January 8, 2018 Category: Dermatology Source Type: research

Generalized Net-Like Erythema and Stroke in a Young Female
A woman in her 40s with Raynaud syndrome and a medical history of stroke presented with erythema, ataxia, and left-sided hemidysesthesia. What is your diagnosis?
Source: JAMA Dermatology - January 1, 2018 Category: Dermatology Source Type: research

Local heat urticaria.
We present a 38-year-old woman with local heat urticaria confirmed by heat provocation testing. Heat urticaria is a rare form of physical urticaria that istriggered by exposure to a heat source, such as hot water or sunlight. Although it is commonly localized and immediate, generalized and delayed onset forms exist. Treatment options include antihistamines and heat desensitization. A brisk, mechanical stroke elicited a linear wheal. Five minutes after exposure to hot water, she developed well-demarcated,erythematous blanching wheals that covered the distal forearm and entire hand. PMID: 29447656 [PubMed - in process]
Source: Dermatol Online J - December 15, 2017 Category: Dermatology Authors: White F, Cobos G, Soter NA Tags: Dermatol Online J Source Type: research