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Questionnaire-based exposome-wide association studies (ExWAS) reveal expected and novel risk factors associated with cardiovascular outcomes in the Personalized Environment and Genes Study
In conclusion, using statistics and machine learning, these findings identify novel potential risk factors for CVD, enable hypothesis generation, provide insights into the complex relationships between risk factors and CVD, and highlight the importance of considering multiple exposures when examining CVD outcomes.PMID:35605674 | DOI:10.1016/j.envres.2022.113463
Source: Environmental Research - May 23, 2022 Category: Environmental Health Authors: Eunice Y Lee Farida Akhtari John S House Ross J Simpson Charles P Schmitt David C Fargo Shepherd H Schurman Janet E Hall Alison A Motsinger-Reif Source Type: research

Cardiovascular Outcomes Post Percutaneous Coronary Intervention in Patients with Obstructive Sleep Apnea and Type  2 Diabetes Mellitus: A Systematic Review and Meta-Analysis
ConclusionOSA was associated with a significant increase in all-cause mortality and MACEs post PCI in these patients with T2DM. Therefore, special care and continuous follow-up might be required for patients with T2DM with associated OSA after PCI. However, as a result of the limited number of participants, further larger studies would be required to confirm these hypotheses.
Source: Diabetes Therapy - June 25, 2020 Category: Endocrinology Source Type: research

Diabetes mellitus is associated with high sleep-time systolic blood pressure and non-dipping pattern.
Conclusion: DM is independently associated with suboptimal 24-hour BP control. This association is mainly attributed to a high sleep-time systolic BP. PMID: 32208051 [PubMed - as supplied by publisher]
Source: Postgraduate Medicine - March 26, 2020 Category: Internal Medicine Tags: Postgrad Med Source Type: research

12 Innovations That Will Change Health Care and Medicine in the 2020s
Pocket-size ultrasound devices that cost 50 times less than the machines in hospitals (and connect to your phone). Virtual reality that speeds healing in rehab. Artificial intelligence that’s better than medical experts at spotting lung tumors. These are just some of the innovations now transforming medicine at a remarkable pace. No one can predict the future, but it can at least be glimpsed in the dozen inventions and concepts below. Like the people behind them, they stand at the vanguard of health care. Neither exhaustive nor exclusive, the list is, rather, representative of the recasting of public health and medic...
Source: TIME: Health - October 25, 2019 Category: Consumer Health News Authors: TIME Staff Tags: Uncategorized HealthSummit19 technology Source Type: news

Obstructive sleep apnea is associated with increased coronary plaque instability: an optical frequency domain imaging study
AbstractObstructive sleep apnea (OSA) is associated with coronary artery disease (CAD) and with an increased risk for myocardial infarction, stroke or death due to cardiovascular disease. Optical frequency-domain imaging (OFDI) is a useful modality for evaluating the characteristics of atherosclerotic plaque. The purpose of the study was to use OFDI to investigate the association of OSA with coronary plaque characteristics in patients undergoing percutaneous coronary intervention (PCI). We retrospectively analyzed OFDI data for coronary artery plaques from 15 patients with OSA and 35 non –OSA patients treated between Oct...
Source: Heart and Vessels - July 10, 2019 Category: Cardiology Source Type: research

Association of obstructive sleep apnea with cardiovascular outcomes after percutaneous coronary intervention: A systematic review and meta-analysis
The relationship between obstructive sleep apnea (OSA) and adverse cardiovascular outcomes in patients undergoing percutaneous coronary intervention (PCI) remains unclear. We performed a systematic review and meta-analysis to assess the impact of OSA on subsequent cardiovascular events after PCI. We searched the PubMed, EMBASE, and Cochrane library from their inceptions to August 5, 2017. We included cohort studies that described the association between OSA (based on apnea-hypopnea index) and cardiovascular outcomes after PCI with stenting. The primary endpoint was major adverse cardiovascular event (MACE), including all-...
Source: Medicine - April 1, 2018 Category: Internal Medicine Tags: Research Article: Meta-Analysis of Observ Studies in Epidemiology Source Type: research

Influence of sleep-disordered breathing assessed by pulse oximetry on long-term clinical outcomes in patients who underwent percutaneous coronary intervention
ConclusionsSDB determined by nocturnal pulse oximetry was associated with worse clinical outcomes in patients who underwent PCI. Screening for SDB with nocturnal pulse oximetry was considered to be important for risk stratification in patients with CAD.
Source: Clinical Research in Cardiology - March 31, 2018 Category: Cardiology Source Type: research

Obstructive sleep apnea increases the risk of cardiac events after percutaneous coronary intervention: a meta-analysis of prospective cohort studies
ConclusionsIn patients after PCI, OSA appears to increase the risk of cardiac death, non-fatal MI, and coronary revascularization.
Source: Sleep and Breathing - April 18, 2017 Category: Respiratory Medicine Source Type: research

Obstructive sleep apnea increases the risk of cardiac events after percutaneous coronary intervention: a meta-analysis of prospective cohort studies.
CONCLUSIONS: In patients after PCI, OSA appears to increase the risk of cardiac death, non-fatal MI, and coronary revascularization. PMID: 28421375 [PubMed - as supplied by publisher]
Source: Sleep and Breathing - April 18, 2017 Category: Sleep Medicine Authors: Qu H, Guo M, Zhang Y, Shi DZ Tags: Sleep Breath Source Type: research

Abstract 236: Coronary Artery Procedures in the Cardiac Catheterization Laboratory After Overnight Call: Are Patients at Higher Risk? Session Title: Poster Session II
Conclusion: There were greater procedural complications when performed post-call compared to no post-call; however, when adjusting for significant baseline variables, there was no significant difference seen between groups. Taking into consideration factors that contributed to procedural complications most likely will improve patient outcomes.
Source: Circulation: Cardiovascular Quality and Outcomes - March 31, 2017 Category: Cardiology Authors: Boudoulas, K. D., Pederzolli, A., Nagaraja, H., Kahaly, O., Magorien, R., Mazzaferri, E. Tags: Session Title: Poster Session II Source Type: research

Sleep disorders may predict heart events after angioplasty
People who have had procedures to open blocked heart arteries after acute coronary syndrome (ACS) may have a higher risk of death, heart failure, heart attack and stroke if they have sleep disorders, such as sleep apnea, compared to those who don't. The presence of sleep disorders in ACS patients is an important predictor of major cardiovascular events after angioplasty.
Source: ScienceDaily Headlines - June 16, 2016 Category: Science Source Type: news

Sleep Apnea Tied to Complications After Angioplasty
Nightly breathing troubles may increase risk of heart attack, stroke following the coronary procedure
Source: WebMD Health - June 15, 2016 Category: Consumer Health News Source Type: news

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