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Procedure: Liver Transplant

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Total 197 results found since Jan 2013.

What Causes Hyperammonemia?
Discussion Reye’s syndrome (RS)is named for Dr. Douglas Reye who along with Drs. G. Morgan and J. Baral described encephalopathy and fatty accumulation and degeneration in children in a 1963 Lancet article. RS usually affects children but can occur at all ages. All organs can be affected but the liver and brain are primarily affected causing liver failure and encephalopathy as toxic metabolites (especially ammonia) accumulate, and intracranial hypertension and cerebral edema occurs. As the ammonia levels begin to rise (> 100 mg/dL) patients lose their appetite, have nausea and emesis and mental status changes whic...
Source: PediatricEducation.org - February 20, 2017 Category: Pediatrics Authors: pediatriceducationmin Tags: Uncategorized Source Type: news

Heat Stroke Leading to Acute Liver Injury & Failure: A Case Series from the Acute Liver Failure Study Group
ConclusionsManagement of ALI and ALF secondary to heat stroke should focus on cooling protocols and supportive care, with consideration of liver transplantation in refractory patients.This article is protected by copyright. All rights reserved.
Source: Liver International - January 26, 2017 Category: Gastroenterology Authors: Brian C. Davis, Holly Tillman, Raymond T. Chung, R. Todd Stravitz, K. Rajender Reddy, Robert J. Fontana, Brendan McGuire, Timothy Davern, William M. Lee, Tags: Rapid Communication Source Type: research

ABCA1/ApoE/HDL Pathway Mediates GW3965-Induced Neurorestoration After Stroke Basic Sciences
Conclusions—ABCA1/ApoE/HDL pathway, at least partially, contributes to GW3965-induced neurorestoration after stroke.
Source: Stroke - January 22, 2017 Category: Neurology Authors: Xu Cui, Michael Chopp, Zhenggang Zhang, Rongwen Li, Alex Zacharek, Julie Landschoot-Ward, Poornima Venkat, Jieli Chen Tags: Ischemia, Lipids and Cholesterol, Metabolism Original Contributions Source Type: research

A machine learning approach to measure and monitor physical activity in children
Publication date: 8 March 2017 Source:Neurocomputing, Volume 228 Author(s): Paul Fergus, Abir J. Hussain, John Hearty, Stuart Fairclough, Lynne Boddy, Kelly Mackintosh, Gareth Stratton, Nicky Ridgers, Dhiya Al-Jumeily, Ahmed J. Aljaaf, Jenet Lunn The growing trend of obesity and overweight worldwide has reached epidemic proportions with one third of the global population now considered obese. This is having a significant medical impact on children and adults who are at risk of developing osteoarthritis, coronary heart disease and stroke, type 2 diabetes, cancers, respiratory problems, and non-alcoholic fatty liver disease...
Source: Neurocomputing - January 16, 2017 Category: Neuroscience Source Type: research

Autosomal dominant polycystic kidney disease: Study of clinical characteristics in an Indian population.
Abstract Autosomal dominant polycystic kidney disease (ADPKD) is the most common hereditary form of kidney disease. Clinical data on this multisystem disorder are scarce from developing countries. We conducted a prospective observational study of the clinical profile of ADPKD patients at a single center over a period of six years. A total of 208 patients were studied. Majority were male (60.6%) and the mean age was 45.8 ± 14.5 years. About 61.5% had early stage (Stages 1-3) of chronic kidney disease (CKD) and 38.5% had advanced CKD (Stages 4 and 5). Clinical features observed included pain abdomen (46.2%), noctur...
Source: Saudi Journal of Kidney Diseases and Transplantation - December 31, 2016 Category: Urology & Nephrology Authors: Vikrant S, Parashar A Tags: Saudi J Kidney Dis Transpl Source Type: research

Outcomes in patients with diabetes 10 years after liver transplantation
ConclusionsIn our study, diabetes was associated with a higher risk of liver graft rejection and cardiovascular events. There was also a trend to higher mortality, although the effect was not statistically significant. These findings suggest that patients with diabetes require a more rigorous pretransplant evaluation and closer monitoring after transplantation, in order to try to reduce associated complications.
Source: Journal of Diabetes - December 31, 2016 Category: Endocrinology Authors: Agust ín Ramos‐prol, David Hervás‐marín, Alia GarcÍa‐castell, Juan Francisco Merino‐torres Tags: Original Article Source Type: research

Chronic hepatothorax due to right diaphragmatic rupture: an anesthetic challenge in a rare case
Conclusions Hepatothorax is a rare condition and its repair may represent an anesthetic challenge. After liver replacement in the abdominal cavity during corrective surgery under general anesthesia complications may occur, particularly associated with pulmonary re-expansion. Effective teamwork and careful planning of surgery, between the surgical and anesthetic teams, are the key to success.
Source: Brazilian Journal of Anesthesiology - November 25, 2016 Category: Anesthesiology Source Type: research

The Role of the Model of End-Stage Liver Disease Score in Predicting Outcomes of Carotid Endarterectomy
Conclusion: High MELD score places asymptomatic patients undergoing carotid endarterectomy at a higher risk of adverse outcomes in the 30 days following surgery. This provides further empirical evidence for risk stratification when considering treatment for these patients. Outcomes of medical management or carotid stenting should be investigated in high-risk patients.
Source: Vascular and Endovascular Surgery - September 13, 2016 Category: Surgery Authors: Krafcik, B. M., Farber, A., Eslami, M. H., Kalish, J. A., Rybin, D., Doros, G., King, E. G., Siracuse, J. J. Tags: Original Manuscripts Source Type: research

Transmission of Balamuthia mandrillaris by Organ Transplantation
Conclusions. Balamuthia can be transmitted through organ transplantation with an observed incubation time of 17–24 days. Clinicians should be aware of Balamuthia as a cause of encephalitis with high rate of fatality, and should notify public health departments and evaluate transplant recipients from donors with signs of possible encephalitis to facilitate early diagnosis and targeted treatment. Organ procurement organizations and transplant centers should be aware of the potential for Balamuthia infection in donors with possible encephalitis and also assess donors carefully for signs of neurologic infection that...
Source: Clinical Infectious Diseases - September 11, 2016 Category: Infectious Diseases Authors: Farnon, E. C., Kokko, K. E., Budge, P. J., Mbaeyi, C., Lutterloh, E. C., Qvarnstrom, Y., da Silva, A. J., Shieh, W.-J., Roy, S. L., Paddock, C. D., Sriram, R., Zaki, S. R., Visvesvara, G. S., Kuehnert, M. J., for the Balamuthia Transplant Investigation Te Tags: ARTICLES AND COMMENTARIES Source Type: research

Cerebrovascular events in 20 years of follow ‐up after liver transplantation: an underestimated issue?
ConclusionLT recipients seem to have a considerably increased risk of CBVE. Long‐term surveillance should take this into account, and screening may be extended accordingly. The progressive impairment of renal function in the long‐term LT survivors may be one reason for the underestimation of CBVE in this patient group.
Source: Clinical Transplantation - August 16, 2016 Category: Transplant Surgery Authors: Wenzel Schoening, Niklas Buescher, Nadja Neidel, Michael Helbig, Andreas Andreou, Andreas Pascher, Marcus Bahra, Johann Pratschke, Daniel Seehofer Tags: Original Article Source Type: research

HDACi Valproic Acid (VPA) and Suberoylanilide Hydroxamic Acid (SAHA) Delay but Fail to Protect against Warm Hepatic Ischemia-Reperfusion Injury
ConclusionsVPA and SAHA delay warm hepatic I/R injury at least in part through modulation of SAPK-activation. However, these HDACi fail to exert organoprotective effects, in this setting. For VPA, belated damage is even aggravated.
Source: PLoS One - August 10, 2016 Category: Biomedical Science Authors: Dietrich A. Ruess Source Type: research

Evaluation of pleth variability index as a predictor of fluid responsiveness during orthotopic liver transplantation
This study was designed to examine whether the PVI can reliably predict fluid responsiveness in OLT and to compare PVI with other hemodynamic indexes that are measured using the PiCCO2 monitoring system. Twenty-five patients were enrolled in this study. Each patient was monitored using the noninvasive Masimo and PiCCO2 monitoring system. PVI was obtained with a Masimo pulse oximeter. Cardiac index was obtained using a transpulmonary thermodilution technique (CITPTD). Stroke volume variation (SVV), pulse pressure variation, and systemic vascular resistance index were measured using the PiCCO2 system. Fluid loading (10 mL/k...
Source: The Kaohsiung Journal of Medical Sciences - August 8, 2016 Category: Universities & Medical Training Source Type: research

Effective evaluation of arterial pulse waveform analysis by two-dimensional stroke volume variation –stroke volume index plots
In this study, we analyzed how we visually interpret hemodynamic data, including stroke volume variation (SVV) and stroke volume (SV) derived from APWA. We performed arithmetic estimation of the SVV –SV relationship and applied measured values to this estimation. We then collected measured values in six anesthesia cases, including three liver transplantations and three other types of surgeries, to apply them to this SVV–SVI (stroke volume variation index) plot. Arithmetic analysis showed th at the relationship between SVV and SV can be drawn as hyperbolic curves. Plotting SVV-SV values in the semi-logarithmic scale sho...
Source: Journal of Clinical Monitoring and Computing - August 3, 2016 Category: Information Technology Source Type: research

Evaluation of cardiac output by bioreactance technique in patients undergoing liver transplantation.
CONCLUSIONS: NICOM provided a comparable CI and SVI trend when compared to the gold standard PiCCO, but it raises concerns as an effective CO monitor because of its tendency to overestimate CI and SVI especially during the state of high cardiac output. PMID: 27461188 [PubMed - as supplied by publisher]
Source: Acta Anaesthesiologica Taiwanica - July 22, 2016 Category: Anesthesiology Authors: Shih PY, Lin WY, Hung MH, Cheng YJ, Chan KC Tags: Acta Anaesthesiol Taiwan Source Type: research

Cerebrovascular Events in 20 ‐years of Follow‐Up after Liver Transplantation. An Underestimated Issue?
ConclusionLT recipients seem to have a considerably increased risk of CBVE. Long‐term surveillance should take this into account and screening may be extended accordingly. The progressive impairment of renal function in the long‐term LT survivors may be one reason for the underestimation of CBVE in this patient group.This article is protected by copyright. All rights reserved.
Source: Clinical Transplantation - July 21, 2016 Category: Transplant Surgery Authors: Wenzel Schoening, Niklas Buescher, Nadja Neidel, Michael Helbig, Andreas Andreou, Andreas Pascher, Marcus Bahra, Johann Pratschke, Daniel Seehofer Tags: Original Article Source Type: research