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Condition: Spinal Cord Injury

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Total 1255 results found since Jan 2013.

Efficacy of rehabilitation interventions evaluated in common neurological conditions in improving participation outcomes: A systematic review
CONCLUSION: There is a limited evidence of the identified rehabilitation interventions to improve participation in common neurological conditions. However, there was a paucity of articles involving individual with Parkinson's disease that met the inclusion criteria.PMID:37501621 | DOI:10.1177/02692155231191383
Source: Clinical Rehabilitation - July 28, 2023 Category: Rehabilitation Authors: Oy éné Kossi Joke Raats Jonas Wellens Mathias Duckaert Stijn De Baets Dominique Van de Velde Peter Feys Source Type: research

Capsaicin, The Vanilloid Receptor TRPV1 Agonist in Neuroprotection: Mechanisms Involved and Significance
Neurochem Res. 2023 Jul 26. doi: 10.1007/s11064-023-03983-z. Online ahead of print.ABSTRACTHot peppers, also called chilli, chilli pepper, or paprika of the plant genus Capsicum (family Solanaceae), are one of the most used vegetables and spices worldwide. Capsaicin (8-methyl N-vanillyl-6-noneamide) is the main pungent principle of hot green and red peppers. By acting on the capsaicin receptor or transient receptor potential cation channel vanilloid subfamily member 1 (TRPV1), capsaicin selectively stimulates and in high doses defunctionalizes capsaicin-sensitive chemonociceptors with C and Aδ afferent fibers. This channe...
Source: Neurochemical Research - July 26, 2023 Category: Neuroscience Authors: Omar M E Abdel-Salam Gyula M ózsik Source Type: research

Sovateltide: First Approval
This article summarizes the milestones in the development of sovateltide leading to this first approval for use in patients with ACIS.
Source: Drugs - July 24, 2023 Category: Drugs & Pharmacology Source Type: research

A review of combined neuromodulation and physical therapy interventions for enhanced neurorehabilitation
Rehabilitation approaches for individuals with neurologic conditions have increasingly shifted toward promoting neuroplasticity for enhanced recovery and restoration of function. This review focuses on exercise strategies and non-invasive neuromodulation techniques that target neuroplasticity, including transcranial magnetic stimulation (TMS), vagus nerve stimulation (VNS), and peripheral nerve stimulation (PNS). We have chosen to focus on non-invasive neuromodulation techniques due to their greater potential for integration into routine clinical practice. We explore and discuss the application of these interventional stra...
Source: Frontiers in Human Neuroscience - July 21, 2023 Category: Neuroscience Source Type: research

Identifying priorities for balance interventions through a participatory co-design approach with end-users - Benn NL, Jervis-Rademeyer H, Benson K, Chan K, Lee JW, Inness EL, Wolfe DL, Alizadeh-Meghrazi M, Masani K, Musselman KE.
BACKGROUND: Most individuals living with spinal cord injuries/diseases (SCI/D) or stroke experience at least one fall each year; hence, the development of interventions and technologies that target balance control is needed. The purpose of this study was t...
Source: SafetyLit - July 19, 2023 Category: International Medicine & Public Health Tags: Economics of Injury and Safety, PTSD, Injury Outcomes Source Type: news

Identifying priorities for balance interventions through a participatory co-design approach with end-users
Most individuals living with spinal cord injuries/diseases (SCI/D) or stroke experience at least one fall each year; hence, the development of interventions and technologies that target balance control is need...
Source: BMC Neurology - July 13, 2023 Category: Neurology Authors: Natasha L. Benn, Hope Jervis-Rademeyer, Kayla Benson, Katherine Chan, Jae W. Lee, Elizabeth L. Inness, Dalton L. Wolfe, Milad Alizadeh-Meghrazi, Kei Masani and Kristin E. Musselman Tags: Research Source Type: research

Bone Marrow-Derived Mononuclear Cells in the Treatment of Neurological Diseases: Knowns and Unknowns
Cell Mol Neurobiol. 2023 Jun 25. doi: 10.1007/s10571-023-01377-x. Online ahead of print.ABSTRACTBone marrow-derived mononuclear cells (BMMNCs) have been used for decades in preclinical and clinical studies to treat various neurological diseases. However, there is still a knowledge gap in the understanding of the underlying mechanisms of BMMNCs in the treatment of neurological diseases. In addition, prerequisite factors for the efficacy of BMMNC administration, such as the optimal route, dose, and number of administrations, remain unclear. In this review, we discuss known and unknown aspects of BMMNCs, including the cell ha...
Source: Cellular and Molecular Neurobiology - June 25, 2023 Category: Cytology Authors: Quyen Thi Nguyen Liem Nguyen Thanh Van T Hoang Trang T K Phan Michael Heke Duc M Hoang Source Type: research

Sensors, Vol. 23, Pages 5827: Development of a Control Strategy in an Isokinetic Device for Physical Rehabilitation
lo Robotic-assisted rehabilitation is currently being applied to improve the effectiveness of human gait rehabilitation and recover the mobility and strength after a stroke or spinal cord injury; a robotic assistant can allow the active participation of the patient and the supervision of the collected data and decrease the labor required from therapists during the patient’s training exercises. The goal of gait rehabilitation with robotic-based assistance is to restore motor function by using diverse control strategies, taking account of the physical interaction with the lower limbs of the patient. Over th...
Source: Sensors - June 22, 2023 Category: Biotechnology Authors: Jorge Andr és Peñaloza-González Sergey Gonz ález-Mejía Jos é Isidro García-Melo Tags: Article Source Type: research

Growth factors and their peptide mimetics for treatment of traumatic brain injury
Bioorg Med Chem. 2023 Jun 10;90:117368. doi: 10.1016/j.bmc.2023.117368. Online ahead of print.ABSTRACTTraumatic brain injury (TBI) is a leading cause of disability in adults, caused by a physical insult damaging the brain. Growth factor-based therapies have the potential to reduce the effects of secondary injury and improve outcomes by providing neuroprotection against glutamate excitotoxicity, oxidative damage, hypoxia, and ischemia, as well as promoting neurite outgrowth and the formation of new blood vessels. Despite promising evidence in preclinical studies, few neurotrophic factors have been tested in clinical trials ...
Source: Bioorganic and Medicinal Chemistry - June 18, 2023 Category: Chemistry Authors: Emily Atkinson Rachael Dickman Source Type: research