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Condition: Spinal Cord Injury

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Total 1255 results found since Jan 2013.

Scoping Review on Brain-Computer Interface-Controlled Electrical Stimulation Interventions for Upper Limb Rehabilitation in Adults: A Look at Participants, Interventions, and Technology
CONCLUSIONS: Future BCI-ES interventional studies could address this gap. Additionally, standardization of device and rehabilitation modalities, and study-appropriate involvement with therapists, can be considered to advance this intervention towards clinical implementation.PMID:37736411 | PMC:PMC10510539 | DOI:10.3138/ptc-2021-0074
Source: Physiotherapy Canada - September 22, 2023 Category: Physiotherapy Authors: Lazar I Jovanovic Hope Jervis Rademeyer Maureen Pakosh Kristin E Musselman Milos R Popovic Cesar Marquez-Chin Source Type: research

Current practice of outpatient rehabilitation services in patients with mobility-impaired paralysis due to stroke or spinal cord injury: a qualitative interview study in Germany
CONCLUSION: Areas of improvement identified focused on: setting rehabilitation goals towards participation, training therapists on evidence-based treatments and shared decision-making, updating the outpatient service catalogue, and implementing coordination actions. Implementation of these recommendations should be evaluated.PMID:37732606 | DOI:10.1080/09638288.2023.2259301
Source: Disability and Rehabilitation - September 21, 2023 Category: Rehabilitation Authors: Tiziana Daniel Tamara Spingler Andreas Hug Norbert Weidner Michel Wensing Charlotte Ullrich Source Type: research

Methods to Study Inflammasome Activation in the Central Nervous System: Immunoblotting and Immunohistochemistry
Methods Mol Biol. 2023;2696:223-238. doi: 10.1007/978-1-0716-3350-2_15.ABSTRACTThe inflammasome is a multiprotein complex that is responsible for mounting an innate immune response through the activation of caspase-1 and the cleavage of interleukin-1β. This multiprotein complex plays an important role in a variety of central nervous system (CNS) diseases and conditions such as Alzheimer's disease, Parkinson's disease, multiple sclerosis, stroke, and traumatic brain injury, among others. Here we describe methodological procedures to carry out immunoblotting and immunohistochemical techniques used to study inflammasome sign...
Source: Molecular Medicine - August 14, 2023 Category: Molecular Biology Authors: Brianna Cyr Juan Pablo de Rivero Vaccari Source Type: research

The Role of Progranulin (PGRN) in the Pathogenesis of Ischemic Stroke
Cell Mol Neurobiol. 2023 Aug 10. doi: 10.1007/s10571-023-01396-8. Online ahead of print.ABSTRACTStroke is a life-threatening medical condition and is a leading cause of disability. Cerebral ischemia is characterized by a distinct inflammatory response starting with the production of various cytokines and other inflammation-related agents. Progranulin (PGRN), a multifunctional protein, is critical in diverse physiological reactions, such as cell proliferation, inflammation, wound healing, and nervous system development. A mature PGRN is anti-inflammatory, while granulin, its derivative, conversely induces pro-inflammatory c...
Source: Cellular and Molecular Neurobiology - August 10, 2023 Category: Cytology Authors: Daryush Purrahman Ali Shojaeian Łukasz A Poniatowski Bart łomiej Piechowski-Jóźwiak Mohammad-Reza Mahmoudian-Sani Source Type: research

Exclusive: For the First Time, New Tech Enables Paralyzed Man To Move and Feel Again
A cluster of researchers surround 45-year-old Keith Thomas, their eyes fixed on his right hand. “Open, open, open,” they urge, cheering when his fingers flutter out to mirror an image on a computer screen and again when they begin to curl back inward. [time-brightcove not-tgx=”true”] Thomas, who was paralyzed from the chest down after a diving accident in July 2020, is able to move his hand again thanks to a cutting-edge clinical trial led by researchers from Northwell Health’s Feinstein Institutes for Medical Research in New York. Chad Bouton, a bioengineer at the Feinstein Institutes who...
Source: TIME: Health - July 28, 2023 Category: Consumer Health News Authors: Jamie Ducharme Tags: Uncategorized feature healthscienceclimate Innovation TIME 2030 Source Type: news

Efficacy of rehabilitation interventions evaluated in common neurological conditions in improving participation outcomes: A systematic review
CONCLUSION: There is a limited evidence of the identified rehabilitation interventions to improve participation in common neurological conditions. However, there was a paucity of articles involving individual with Parkinson's disease that met the inclusion criteria.PMID:37501621 | DOI:10.1177/02692155231191383
Source: Clinical Rehabilitation - July 28, 2023 Category: Rehabilitation Authors: Oy éné Kossi Joke Raats Jonas Wellens Mathias Duckaert Stijn De Baets Dominique Van de Velde Peter Feys Source Type: research