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Diffuse low-grade glioma misdiagnosed as acute cerebral infarction: A case report
We report a case of DLGG detected by computed tomography and magnetic resonance imaging (MRI). Patient concerns: A 58-year-old man suddenly phantom smells for half an hour and was previously healthy. Diagnoses: Computed tomography findings showed a leaf-shaped slightly hypodense shadow in the right temporal lobe with no obvious mass effect and an unclear boundary. MRI findings showed diffuse and slightly longer T1-weighted imaging (T1WI)/T2-weighted imaging (T2WI)signal in the right temporal lobe and hippocampus, slight hyperintensity on diffusion-weighted imaging, diffuse swelling in the right temporal lobe ...
Source: Medicine - September 2, 2022 Category: Internal Medicine Tags: Research Article: Clinical Case Report Source Type: research

A Stroke Alert With Unexpected Outcome
Conclusion: We report a case of thrombolysis administered in a patient with high-grade glioma with no apparent complications.
Source: The Neurologist - September 1, 2022 Category: Neurology Tags: Case Report/Case Series Source Type: research

Verbal and memory deficits caused by aphasic status epilepticus after resection of a left temporal lobe glioma
CONCLUSION: Prolonged ASE can induce verbal and memory deficits. Early intervention with intravenous anesthetics is required to obtain a favorable neurological prognosis.PMID:34992930 | PMC:PMC8720448 | DOI:10.25259/SNI_1120_2021
Source: Surgical Neurology International - January 7, 2022 Category: Neurosurgery Authors: Misaki Kamogawa Naoki Ikegaya Yohei Miyake Takahiro Hayashi Hidetoshi Murata Kensuke Tateishi Tetsuya Yamamoto Source Type: research

Unilateral basal ganglia restricted diffusion in anti ‐leucine‐rich glioma‐inactivated 1 encephalitis mimicking cerebral infarction: A report on two cases and literature review
ConclusionOur report adds to the heterogeneity of anti-leucine-rich glioma-inactivated  1 encephalitis and highlights the need to consider this diagnosis in patients who present atypically.
Source: Clinical and Experimental Neuroimmunology - July 23, 2021 Category: Neurology Authors: Mervyn Q. W. Poh, Hui Jin Chiew, Zheyu Xu, Kevin Tan, Tchoyoson C. C. Lim, Tianrong Yeo Tags: CASE REPORT Source Type: research

Common genetic variation influencing human white matter microstructure
Brain regions communicate with each other through tracts of myelinated axons, commonly referred to as white matter. We identified common genetic variants influencing white matter microstructure using diffusion magnetic resonance imaging of 43,802 individuals. Genome-wide association analysis identified 109 associated loci, 30 of which were detected by tract-specific functional principal components analysis. A number of loci colocalized with brain diseases, such as glioma and stroke. Genetic correlations were observed between white matter microstructure and 57 complex traits and diseases. Common variants associated with whi...
Source: Science: Current Issue - June 17, 2021 Category: Science Authors: Zhao, B., Li, T., Yang, Y., Wang, X., Luo, T., Shan, Y., Zhu, Z., Xiong, D., Hauberg, M. E., Bendl, J., Fullard, J. F., Roussos, P., Li, Y., Stein, J. L., Zhu, H. Tags: Genetics, Online Only r-articles Source Type: research

Clinical and radiological aspects of bilateral temporal abnormalities: pictorial essay
Abstract The temporal lobes are vulnerable to several diseases, including infectious, immune-mediated, degenerative, vascular, metabolic, and neoplastic processes. Therefore, lesions in the temporal lobes can pose a diagnostic challenge for the radiologist. The temporal lobes are connected by structures such as the anterior commissure, corpus callosum, and hippocampal commissure. That interconnectedness favors bilateral involvement in various clinical contexts. This pictorial essay is based on a retrospective analysis of case files from a tertiary university hospital and aims to illustrate some of the conditions that simul...
Source: Radiologia Brasileira - March 26, 2021 Category: Radiology Source Type: research

Stroke Mimics and Chameleons from the Radiological Viewpoint of Glioma Diagnosis.
This study enrolled 214 patients who underwent tumor resection for suspected glioma. Clinical characteristics and radiological findings of the patients were compared between the masquerade findings group, which was further divided into two groups: the stroke chameleons and stroke mimics according to their final diagnosis, and the intelligible findings group.Stroke chameleons and stroke mimics were significantly higher in age and smaller in lesion size than the intelligible findings group. In the multivariate analysis, the predictive factor of the masquerade finding group was higher age and smaller size. Stroke mimics group...
Source: Neurologia Medico-Chirurgica - January 6, 2021 Category: Neurosurgery Tags: Neurol Med Chir (Tokyo) Source Type: research

Delayed radiation-induced stroke mimics recurrent tumor in and adolescent with remote history of low-grade brainstem glioma
A 13-year-old female was diagnosed with a ponto- medullary brainstem glioma and following unsuccessful treatment with chemotherapy, underwent focal photon intensity modulated radiation therapy that resulted in a favorable response. Ten years later, the patient presented with acute onset left-sided hemiplegia and headaches. Magnetic resonance imaging (MRI) at presentation showed a large contrast- enhancing lesion with surrounding vasogenic edema and reduced diffusivity on diffusion- weighted imaging most concerning for a high grade secondary malignancy (Figure 1).
Source: Pediatric Neurology - June 4, 2019 Category: Neurology Authors: Lianne Q. Chau, Michael L. Levy, John Ross Crawford Tags: Short Communication Source Type: research

Delayed Radiation-Induced Stroke Mimics Recurrent Tumor in an Adolescent With Remote History of Low-Grade Brainstem Glioma
This 13-year-old girl was diagnosed with a ponto-medullary brainstem glioma, and following unsuccessful treatment with chemotherapy, she underwent focal photon intensity-modulated radiation therapy that resulted in a favorable response. Ten years later, she presented with acute left hemiplegia and headaches. Magnetic resonance imaging (MRI) at presentation showed a large contrast-enhancing lesion with surrounding vasogenic edema and reduced diffusivity on diffusion-weighted imaging, most concerning for a high-grade secondary malignancy (Fig 1).
Source: Pediatric Neurology - June 4, 2019 Category: Neurology Authors: Lianne Q. Chau, Michael L. Levy, John R. Crawford Tags: Clinical Letter Source Type: research

Why is Clinical fMRI in a Resting State?
Conclusions Despite some perceived impediments to expanding clinical rs-fMRI use, neuroradiologists were generally enthusiastic about rs-fMRI in research and clinical applications, believing that their current workplace MRI systems are suitable for rs-fMRI acquisition. Many of the concerns associated with using rs-fMRI in clinical contexts are related to: (1) developing better methods for minimizing physiological noise effects, (2) improving methods for detecting the spatial characteristics of clinically-relevant brain processing systems in individual patients, and (3) overcoming remaining standardization, training, and r...
Source: Frontiers in Neurology - April 23, 2019 Category: Neurology Source Type: research

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