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Total 6681 results found since Jan 2013.

The prevalence and prognosis of asymptomatic intracranial atherosclerosis in a community-based population: Results based on high-resolution magnetic resonance imaging
CONCLUSIONS: We found that ICAD detected using HR-MRI increases the long-term risk of a first-ever ischemic stroke in a stroke-free population, suggesting that the current primary prevention protocol of stroke awaits further optimization.PMID:37738517 | DOI:10.1111/ene.16057
Source: Atherosclerosis - September 22, 2023 Category: Cardiology Authors: Shengde Li Mingyu Tang Dingding Zhang Fei Han Lixin Zhou Ming Yao Mingli Li Liying Cui Shuyang Zhang Bin Peng Zhengyu Jin Yicheng Zhu Jun Ni Source Type: research

Brain MRI correlations with disease burden and biomarkers in Fabry disease
ConclusionBrain MRI revealed progressive lacunar infarctions, white matter hyperintensities, and decreased brain volume in patients with Fabry disease. Brain MRI lesions were closely related to onset-age; disease duration, severity, burden; and plasma  Lyso-Gb3. However, they were not associated with sex, α-galactosidase A activity, orGLA mutation type.
Source: Journal of Neurology - September 20, 2023 Category: Neurology Source Type: research

Pure Sensory Lacunar Infarction in the Thalamus Presented as Bilateral Hypogeusia: A Case Report
CONCLUSION: The exact gustatory pathway in humans remains uncertain nowadays. First, there were few reports about dysgeusia, which might be related to clinical neglect of taste deficits. Second, our knowledge of the human gustatory pathway depends solely on sporadic cases of taste-involved brain lesions. We reported a case of bilateral hypogeusia after right thalamic infarction. This finding indicates that, although there might be laterality of gustatory fibers to the left hemisphere, anatomical variations may exist in the human gustatory system. More research is needed to elucidate the understanding of the gustatory pathw...
Source: Acta Neurologica Taiwanica - September 19, 2023 Category: Neurology Authors: Yu-Chun Wang I-Hsu Chen Poyin Huang Source Type: research

Case report: Heterozygous mutation in HTRA1 causing typical cerebral autosomal recessive arteriopathy with subcortical infarcts and leukoencephalopathy
Conclusion: This case suggests that patients carrying a heterozygous mutation in G905A may also have typical clinical features of CARASIL, which allows us to have a more comprehensive understanding of CARASIL.
Source: Frontiers in Genetics - September 18, 2023 Category: Genetics & Stem Cells Source Type: research

Incidence, characteristics and outcome of post-stroke recrudescence in the Chinese population: a single-centre observational study
Conclusions PSR is not uncommon in patients presenting with stroke symptoms and can be distinguished from TIA and SMs based on a combination of clinical features and trigger in the Chinese population. The neurological deficits of patients with PSR often resolve within several days following the resolution of the trigger.
Source: BMJ Open - September 13, 2023 Category: General Medicine Authors: Pu, M.-J., Yu, J.-L., Hu, X., Deng, L., Chen, C., Lv, X.-N., Li, Z.-Q., Wang, Z.-J., Xie, P., Li, Q. Tags: Open access, Neurology Source Type: research

The Piano Man: A Case Report of Anterior Thalamic Infarct with Dementia and Preserved Music Ability
CONCLUSIONS: The case has implications for understanding the complex integrative functions of the thalamus, including how profound impairment can simultaneously present with cognitive strengths that may not be captured by performance on neuropsychological testing. This case also suggests that magnetic resonance imaging may be indicated in cases presenting with vascular risk factors and sudden onset cognitive impairment, given that computed tomography may not be sensitive to small subcortical infarcts.PMID:37699427 | DOI:10.1093/arclin/acad069
Source: Archives of Clinical Neuropsychology - September 12, 2023 Category: Psychiatry & Psychology Authors: Ashleigh F Parker Theone S E Paterson Tamara Goranson Jodie R Gawryluk Source Type: research

Noninvasive Characterization of Metabolic Changes in Ischemic Stroke Using Z-spectrum-fitted Multiparametric Chemical Exchange Saturation Transfer-weighted Magnetic Resonance Imaging
ConclusionThe Z-spectrum-fitted multiparametric CEST-MRI can comprehensively detect metabolic alterations in ischemic brain tissues.
Source: Journal of Huazhong University of Science and Technology -- Medical Sciences -- - September 11, 2023 Category: Research Source Type: research

Acute and subacute neurovascular impact of cryptogenic air emboli
CONCLUSION: This case highlights that cerebral air emboli can cause delayed ischemia that may not be appreciated on initial imaging. As such, affected patients may require intensive neurocritical care management, close neurologic monitoring, and repeat imaging irrespective of initial radiographic findings.PMID:37680929 | PMC:PMC10481802 | DOI:10.25259/SNI_382_2023
Source: Surgical Neurology International - September 8, 2023 Category: Neurosurgery Authors: Christine E Gummerson Melvin Parasram Teng J Peng John M Picard Peter A Kahn Evan Angelus Shivani Bhatt Adam de Havenon Adam S Jasne Jessica Magid-Bernstein Source Type: research