Delayed Radiation-Induced Stroke Mimics Recurrent Tumor in an Adolescent With Remote History of Low-Grade Brainstem Glioma

This 13-year-old girl was diagnosed with a ponto-medullary brainstem glioma, and following unsuccessful treatment with chemotherapy, she underwent focal photon intensity-modulated radiation therapy that resulted in a favorable response. Ten years later, she presented with acute left hemiplegia and headaches. Magnetic resonance imaging (MRI) at presentation showed a large contrast-enhancing lesion with surrounding vasogenic edema and reduced diffusivity on diffusion-weighted imaging, most concerning for a high-grade secondary malignancy (Fig 1).

Source: Pediatric Neurology - June 4, 2019 Category: Neurology Authors: Lianne Q. Chau, Michael L. Levy, John R. Crawford Tags: Clinical Letter Source Type: research