Filtered By:
Cancer: Lymphoma

This page shows you your search results in order of date. This is page number 19.

Order by Relevance | Date

Total 355 results found since Jan 2013.

Enlargement of deep medullary veins during the early clinical course of Sturge-Weber syndrome
We report a retrospective case series of patients with relapsed and refractory CNS lymphoma treated with ibrutinib.
Source: Neurology - December 25, 2016 Category: Neurology Authors: Pilli, V. K., Chugani, H. T., Juhasz, C. Tags: MRI, PET, Other cerebrovascular disease/ Stroke, Developmental disorders CLINICAL/SCIENTIFIC NOTES Source Type: research

Neuroprotective effects of polydatin against mitochondrial-dependent apoptosis in the rat cerebral cortex following ischemia/reperfusion injury.
Authors: Gao Y, Chen T, Lei X, Li Y, Dai X, Cao Y, Ding Q, Lei X, Li T, Lin X Abstract The neuroprotective effect of polydatin (PD) against hemorrhagic shock-induced mitochondrial injury has been described previously, and mitochondrial dysfunction and apoptosis were reportedly involved in ischemic stroke. In the present study the neuroprotective effect of PD in preventing apoptosis was evaluated following induction of focal cerebral ischemia by middle cerebral artery occlusion (MCAO) in rats. PD (30 mg/kg) was administered by caudal vein injection 10 min prior to ischemia/reperfusion (I/R) injury. 24 h following...
Source: Molecular Medicine Reports - November 16, 2016 Category: Molecular Biology Tags: Mol Med Rep Source Type: research

Intravascular lymphoma mimicking vasculitis
This report documents the presence of intravascular lymphoma diagnosed on a brain biopsy in a 60-year-old man. He initially presented 6months before brain biopsy with chest pain and hypotension, warranting coronary artery bypass graft surgery. Four months later, he presented with signs attributed to a stroke (diaphoresis, slumped over in a chair and left hand weakness). He subsequently developed a sudden onset wide-based gait, left leg numbness, word finding difficulties and worsening confusion. A MRI study showed multiple infarcts in the brain, including cerebellum. Invasive angiogram suggested vasculitis. He was started ...
Source: Journal of Clinical Neuroscience - November 10, 2016 Category: Neuroscience Source Type: research

Ntox-08. safety of intra-arterial chemotherapy in the treatment of brain tumours
The treatment of brain tumors is greatly limited the delivery impediment caused by the blood-brain barrier and blood-tumor barrier. To circumvent this limitation, different approaches have been studied, including intra-arterial delivery. Because of a significant local increase in plasma-peak concentration, this strategy increases the local area under the curve, and translates into a 3 to 5.5 fold increase in intra-tumoral chemotherapy concentration. However, intra-arterial chemotherapy in the treatment of brain tumors has a notoriously bad name, thanks to prior trials led in past decades showing significant neurotoxicities...
Source: Neuro-Oncology - November 6, 2016 Category: Cancer & Oncology Authors: Fortin, D., Caux, S., Gahide, G. Tags: NEUROTOXICITY OF THERAPY Source Type: research

Rare-33. intracerebral hemorrhage as rare complication of intravascular lymphoma
Intravascular lymphoma (IVL) is an aggressive multifocal large cell lymphoma, characterized by neoplastic proliferation and vascular occlusion within the lumina of arterioles, capillaries and venules with a predilection for the central nervous system and skin. The clinical presentation is frequently non-specific and may consist of changes in mental status, focal neurological deficits, seizures, fevers of unknown origin and skin changes. Due to the rarity and absence of specific diagnostic procedures apart from biopsy, diagnosis is difficult and often post-mortem. Neuroimaging findings vary widely, ranging from normal to di...
Source: Neuro-Oncology - November 6, 2016 Category: Cancer & Oncology Authors: Czap, A., Mantica, M. Tags: RARE TUMORS Source Type: research

Rare-39. intravascular lymphoma affecting the central nervous system: features and outcomes in a case series of the primary cns lymphoma collaborative group (ipcg)
We present a retrospective case series of 72 adults with IVL from 16 cancer centers in 6 countries. IVL was present in the CNS in 55 cases, with a mean age of 61.6 years and more than 90% of patients having neurological deficits at the time of diagnosis. There was a mean diagnostic delay of 20 weeks after presentation of stroke-like symptoms or myelopathy. Eighty-five percent had a poor functional status with an Eastern Cooperative Oncology Group (ECOG) performance status ≥2 with another eight percent diagnosed post-mortem. Serum LDH was elevated in 87% of available patients with no correlation with treatment outco...
Source: Neuro-Oncology - November 6, 2016 Category: Cancer & Oncology Authors: Zukas, A., Bennani, N., Chou, C., Johnston, P., ONeill, B. P., Nijland, M., Batchelor, T., Nayak, L., Mrugala, M., Low, J., Omuro, A., Ferreri, A., Nishikawa, R., Mishima, K., Fox, C., Wilson, W., Houillier, C., Chamberlain, M., Schiff, D. Tags: RARE TUMORS Source Type: research

September Is Childhood Obesity Month -- Get The Facts
The obesity epidemic continues to dominate headlines--and for good reason. Obesity is a leading cause of heart disease, diabetes, high blood pressure, and stroke. Many of these conditions occur in adults but often begin in childhood. This September is National Childhood Obesity Awareness Month. By knowing the facts and taking steps to help your children live a healthier lifestyle, childhood obesity and its resulting complications may be prevented. The Facts According to the Centers for Disease Control & Prevention (CDC), one in three children in the U.S. is overweight or obese. Childhood obesity doubled in children and ...
Source: Healthy Living - The Huffington Post - September 28, 2016 Category: Consumer Health News Source Type: news

OS5.8 Intravascular lymphoma affecting the central nervous system: features and outcomes in a case series of the Primary CNS Lymphoma Collaborative Group (IPCG)
We present a retrospective case series of 65 adults with IVL from 14 cancer centers in 6 countries. IVL was restricted to the CNS in 29 cases, with a mean age of 60 years and 91% of patients having neurological deficits at the time of diagnosis. There was a mean diagnostic delay of 20 weeks after presentation of stroke-like symptoms or myelopathy. Ninety-three percent had a poor functional status with an Eastern Cooperative Oncology Group (ECOG) performance status ≥2. Serum LDH was elevated in 87% of patients with no correlation with treatment outcome. Frontline treatment with intravenous high-dose methotrexate-bas...
Source: Neuro-Oncology - September 20, 2016 Category: Cancer & Oncology Authors: Zukas, A. M., Bennani, N., Chou, C., Johnston, P., ONeill, B., Nijland, M., Batchelor, T., Nayak, L., Mrugala, M., Schiff, D. Tags: OS5 Glioma: Clinical Source Type: research

Diffuse Large B Cell Lymphoma in a Prosthetic Aortic Graft
We describe the case of a 70-year-old man with Marfan Syndrome who was found to have Diffuse Large B Cell Lymphoma (DLBCL) within an ascending aortic graft, his native aortic arch and arch vessels. Ten years previously he had undergone a Bentall's Procedure for a dilated aortic root. He presented with a left middle cerebral artery stroke. Computed tomography (CT) scan revealed multiple filling defects within the aortic arch and branch vessels suggestive of thrombus. Following the stroke, his neurological deficit improved.
Source: Heart, Lung and Circulation - August 29, 2016 Category: Cardiology Authors: David Bell, David Marshman Source Type: research

Comorbidities in patients with Primary Sj ögren's Syndrome and Systemic Lupus Erythematosus: A comparative registries‐based study
Conclusions: pSS patients have consistently less serious CV comorbidity burden and a lower prevalence of severe infection than those with SLE. In contrast, their risk of lymphoma was greater. This article is protected by copyright. All rights reserved.
Source: Arthritis Care and Research - August 25, 2016 Category: Rheumatology Authors: I ñigo Rúa‐Figueroa, Mónica Fernández de Castro, José L. Andreu, Carlos Sanchez‐Piedra, Víctor Martínez‐Taboada, Alejandro Olivé, Javier López‐Longo, José Rosas, María Galindo, Jaime Calvo‐Alén, Antonio Fernández‐Nebro, Fernando A Tags: Original Article Source Type: research

Glioblastoma mimicking meningioma: report of 2 cases
Glioblastoma can mimic various pathologies, including arteriovenous malformation, hemorrhage from ischemic stroke, cerebral contusion, metastatic disease, lymphoma, and infection. The literature is limited regarding diagnostic confusion with meningioma. Herein, we present two patients that exhibited imaging, including cerebral angiography during preoperative embolization, which was consistent with meningioma, but where final surgical diagnosis revealed glioblastoma.
Source: World Neurosurgery - August 22, 2016 Category: Neurosurgery Authors: Mohit Patel, Ha Nguyen, Ninh Doan, Michael Gelsomino, Saman Shabani, Wade Mueller Tags: Case Reports Source Type: research

Calcium/calmodulin ‐dependent protein kinase kinase β is neuroprotective in stroke in aged mice
This study demonstrates that CaMKK β is neuroprotective following stroke in aged mice. Inhibition of CaMKK β worsened stroke outcome by reducing expression of prosurvival factors, as well as the levels of proteins important for the integrity of blood–brain barrier, and increasing proinflammatory cytokines in the serum after stroke. Conversely, the overexpression of CaMKK β reduced infarcts and behavioral deficits in aged mice.
Source: European Journal of Neuroscience - August 16, 2016 Category: Neuroscience Authors: Lin Liu, Hui Yuan, Kyle Denton, Xue ‐jun Li, Louise McCullough, Jun Li Tags: Clinical and Translational Neuroscience Source Type: research

Effects of microRNA-21 and microRNA-24 inhibitors on neuronal apoptosis in ischemic stroke.
CONCLUSION: MiRNA-24 but not miR-21 inhibitor prevents apoptosis in ischemic stroke by regulation of Bcl-xL, Caspase-3 and HSP70. PMID: 27508039 [PubMed]
Source: American Journal of Translational Research - August 13, 2016 Category: Research Tags: Am J Transl Res Source Type: research

Zinc carnosine works with bovine colostrum in truncating heavy exercise-induced increase in gut permeability in healthy volunteers Dietary supplements
Conclusion: ZnC, taken alone or with colostrum, increased epithelial resistance and the TJ structure and may have value for athletes and in the prevention of heat stroke in military personnel. This trial was registered at www.isrctn.com as ISRCTN51159138.
Source: American Journal of Clinical Nutrition - July 31, 2016 Category: Nutrition Authors: Davison, G., Marchbank, T., March, D. S., Thatcher, R., Playford, R. J. Tags: Dietary supplements Source Type: research

Neuroimaging in Central Nervous System Lymphoma
Primary central nervous system lymphoma (PCNSL) is a rare aggressive high-grade type of extranodal lymphoma. PCNSL can have a variable imaging appearance and can mimic other brain disorders such as encephalitis, demyelination, and stroke. In addition to PCNSL, the CNS can be secondarily involved by systemic lymphoma. Computed tomography and conventional MRI are the initial imaging modalities to evaluate these lesions. Recently, however, advanced MRI techniques are more often used in an effort to narrow the differential diagnosis and potentially inform diagnostic and therapeutic decisions.
Source: Hematology/Oncology Clinics of North America - July 28, 2016 Category: Cancer & Oncology Authors: Seyed Ali Nabavizadeh, Arastoo Vossough, Mehrdad Hajmomenian, Reza Assadsangabi, Suyash Mohan Source Type: research