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Nutrition: Selenium

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Total 69 results found since Jan 2013.

Sex difference in the association between plasma selenium and first stroke: a community-based nested case-control study
ConclusionOur study indicated a significant,non-linear, negative association between plasma selenium and first stroke in males but not in females.Trial registrationChiCTR1800017274.
Source: Biology of Sex Differences - May 29, 2021 Category: Biology Source Type: research

Evident lower blood levels of multiple nutritional compounds and highly prevalent malnutrition in sub-acute stroke patients with or without dysphagia
This study shows that malnutrition is highly prevalent in sub-acute stroke patients during rehabilitation. Even though patients with OD were more likely to be malnourished, blood levels of specific nutritional compounds were similarly lower in stroke patients with or without OD compared to healthy reference subjects. Furthermore, subgroup analysis showed similarly lower blood levels of specific nutritional compounds in patients that are normal nourished vs. patients with (risk of) malnutrition. This might imply disease-specific changes in blood levels on top of overall protein-energy malnutrition. The results of the curren...
Source: Frontiers in Neurology - January 10, 2023 Category: Neurology Source Type: research

Serum mercury concentration and the risk of ischemic stroke: The REasons for Geographic and Racial Differences in Stroke Trace Element Study.
CONCLUSION: This study does not support an association between mercury and the incidence of ischemic stroke within a population with low-to-moderate level of exposure. Further studies are needed to explore the possibility of mercury-induced ischemic stroke toxicity in other populations at higher exposure levels. PMID: 29738916 [PubMed - as supplied by publisher]
Source: Environment International - May 4, 2018 Category: Environmental Health Authors: Chen C, Xun P, McClure LA, Brockman J, MacDonald L, Cushman M, Cai J, Kamendulis L, Mackey J, He K Tags: Environ Int Source Type: research

Dietary and blood selenium are inversely associated with the prevalence of stroke among Inuit in Canada
In conclusion, blood and dietary selenium are reversely associated with the prevalence of stroke in Inuit, which follows an L-shaped relationship. Whether this relationship applies to other population needs further investigation.
Source: Journal of Trace Elements in Medicine and Biology - September 7, 2017 Category: Biochemistry Source Type: research

Plasma selenium and the risk of first stroke in adults with hypertension: a secondary analysis of the China Stroke Primary Prevention Trial
CONCLUSIONS: In summary, there was a significant inverse association between plasma Se and risk of first stroke in Chinese adults with hypertension, especially among those with higher baseline folate concentrations and those with higher time-averaged SBP over the treatment period.Trial registration number: NCT00794885URL of registration: https://www.clinicaltrials.gov/ct2/show/NCT00794885?term=NCT00794885&draw=2&r.PMID:34549258 | DOI:10.1093/ajcn/nqab320
Source: The American Journal of Clinical Nutrition - September 22, 2021 Category: Nutrition Authors: Zhuo Wang Hai Ma Yun Song Tengfei Lin Lishun Liu Ziyi Zhou Yaping Wei Xiao Huang Ping Chen Chengzhang Liu Youbao Li Binyan Wang Jianping Li Yan Zhang Yong Huo Hao Zhang Xiping Xu Xianhui Qin Huiyuan Guo Source Type: research

Correlation between dietary selenium intake and stroke in the National Health and Nutrition Examination Survey 2003-2018
CONCLUSIONS: Dietary selenium had a negative and non-linear correlation with the risk of stroke in adults. The correlation varied across different population subgroups.KEY MESSAGESDietary selenium had a negative and non-linear correlation with the risk of stroke in adults.Non-linear negative correlation trends were observed in subpopulations of females, age <60 years, poverty-income ratio <2.14, overweight and obesity, hypertension, non-diabetes, and non-anaemia.Dietary selenium intake of approximately 105 μg per day has an optimum effect on stroke.PMID:35594240 | DOI:10.1080/07853890.2022.2058079
Source: Annals of Medicine - May 20, 2022 Category: Internal Medicine Authors: Wenrui Shi Liang Su Jian Wang Fangze Wang Xu Liu Jianxin Dou Source Type: research

In silico identification of molecular mechanisms for stroke risk caused by heavy metals and their mixtures: sponges and drugs involved
This study used various approaches and databases to evaluate the molecular processes and identify miRNA sponges and drugs associated with the development of stroke caused by heavy metals and their combinations. We found that the genes ALB (albumin), IL1B (Interleukin-1β), F2 (coagulation factor II), APOA1 (apolipoprotein A1), IL6 (Interleukin 6), and NOS2 (nitric oxide synthase 2) were linked to the development of strokes by 18 chemicals and a combination of cadmium, copper, and lead. These results may point to the significance of detoxification and neuroinflammation in stroke as well as the potential for targeting these ...
Source: Neurotoxicology - April 30, 2023 Category: Neurology Authors: Hai Duc Nguyen Min-Sun Kim Source Type: research

Evaluation of Selenium Supplementation in Acute Ischemic Stroke Outcome: An Outcome Assessor Blind, Randomized, Placebo-Controlled, Feasibility Study
Conclusions: Selenium selenite supplementation in acute ischemic stroke can improve short-term outcome but cannot influence the long-term outcome.
Source: Neurology India - February 28, 2022 Category: Neurology Authors: Athena Sharifi-Razavi Narges Karimi Hamed Jafarpour Source Type: research

Association Between Blood Selenium Levels and Stroke: A Study Based on the NHANES (2011-2018)
Biol Trace Elem Res. 2023 Apr 1. doi: 10.1007/s12011-023-03649-5. Online ahead of print.ABSTRACTAt present, the association between circulating selenium and stroke is still in dispute. Thus, this study aimed to ascertain the association with a larger sample size than the previous study, based on the National Health and Nutrition Examination Survey (NHANES) from 2011 to 2018. In total, 13755 adults over the age of 20 years were included in our study. Multivariate logistic regression models were applied to analyze the correlation between blood selenium levels and stroke. The smooth curve fitting was performed to test the dos...
Source: Biological Trace Element Research - April 2, 2023 Category: Biology Authors: Kunsheng Zhao Yun Zhang Wenhai Sui Source Type: research

A specific dietary intervention to restore brain structure and function after ischemic stroke
Occlusion of the middle cerebral artery (MCAo) is among the most common causes of ischemic stroke in humans. Cerebral ischemia leads to brain lesions existing of an irreversibly injured core and an ischemic boundary zone, the penumbra, containing damaged but potentially salvageable tissue. Using a transient occlusion (30 min) of the middle cerebral artery (tMCAo) mouse model in this cross-institutional study we investigated the neurorestorative efficacy of a dietary approach (Fortasyn) comprising docosahexaenoic acid, eicosapentaenoic acid, uridine, choline, phospholipids, folic acid, vitamins B12, B6, C, and E, and seleni...
Source: Theranostics - September 12, 2017 Category: Molecular Biology Authors: Maximilian Wiesmann, Bastian Zinnhardt, Dirk Reinhardt, Sarah Eligehausen, Lydia Wachsmuth, Sven Hermann, Pieter J Dederen, Marloes Hellwich, Michael T Kuhlmann, Laus M Broersen, Arend Heerschap, Andreas H Jacobs, Amanda J Kiliaan Tags: Research Paper Source Type: research