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Infectious Disease: Meningitis

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Total 603 results found since Jan 2013.

Comment The SeLECT score is inappropriate to predict post-stroke epilepsy
Causes of post-stroke epilepsy are manifold and not just restricted to the stroke itself (primary post-stroke epilepsy). These causes range from premorbid conditions already present before the stroke, to morbidity that develops after the stroke, either as a complication of, or independent of, the stroke. Seizures associated with a pre-existing disposition (eg, meningitis, head trauma, or encephalopathy caused by, for example, diabetes or hypertension) can be triggered by stroke or by co-pathologies developing after a stroke (secondary post-stroke epilepsy).
Source: Lancet Neurology - January 18, 2018 Category: Neurology Authors: Josef Finsterer Tags: Comment Source Type: research

Childhood Stroke: Results of 130 Children From a Reference Center in Central Anatolia, Turkey
Conclusion: Tuberculous meningitis is still a risk factor for arterial ischemic stroke in Turkey. Arterial ischemic stroke in the first year of life and recurrent arterial ischemic stroke represent poor prognostic features.
Source: Pediatric Neurology - January 27, 2014 Category: Neurology Authors: Huseyin Per, Ekrem Unal, Hatice Gamze Poyrazoglu, Mehmet Akif Ozdemir, Halil Donmez, Hakan Gumus, Kazım Uzum, Mehmet Canpolat, Basak Nur Akyildiz, Abdulhakim Coskun, Ali Kurtsoy, Sefer Kumandas Tags: Original Articles Source Type: research

Ischemic stroke and infectious diseases in low-income and middle-income countries
Purpose of review To address the important relationships between stroke and infection, focusing on the most frequent infections found in low-income and middle-income countries. Recent findings Stroke is one of the leading causes of mortality and disability worldwide, with a great proportion of the stroke burden occurring in low-income and middle-income countries. Infectious diseases are still a great health problem in developing countries and it is possible that the proportion of infection-related strokes is greater in these nations. Infectious diseases and stroke have a bidirectional relationship. Common infections m...
Source: Current Opinion in Neurology - January 13, 2019 Category: Neurology Tags: CEREBROVASCULAR DISEASE: Edited by Didier Leys Source Type: research

Antithrombotic Therapy for Secondary Stroke Prevention in Bacterial Meningitis in Children
Conclusion: In this small sample, heparin and ASA appeared to be safe in childhood bacterial meningitis complicated by stroke and may be effective in improving outcome. Heparin may be more effective than aspirin in preventing recurrent infarction.
Source: The Journal of Pediatrics - July 24, 2014 Category: Pediatrics Authors: Cyrus Boelman, Manohar Shroff, Ivanna Yau, Bruce Bjornson, Susan Richrdson, Gabrielle deVeber, Daune MacGregor, Mahendranathn Moharir, Rand Askalan Tags: Original Articles Source Type: research

Early temperature and mortality in critically ill patients with acute neurological diseases: trauma and stroke differ from infection
Conclusions The relationship between peak temperature in the first 24 h after ICU admission and in-hospital mortality differs for TBI/stroke compared to CNS infection. For CNS infection, increased temperature is not associated with increased risk of death.
Source: Intensive Care Medicine - February 2, 2015 Category: Intensive Care Source Type: research

Rheumatoid meningitis: A rare cause of aseptic meningitis with frequently stroke-like episodes
Conclusions RM is a rare manifestation of RA and often presents with stroke-like episodes. It is currently not implemented in the workup of aseptic meningitis in national guidelines. Crucial clues for diagnosis included recurrent stroke-like episodes refractory to antiepileptic treatment, headache and constitutional symptoms, meningeal enhancement on MRI, CSF pleocytosis, and positive serology findings for ACPA and RF. Prognosis is favorable with early immunosuppressive treatment.
Source: Neurology Clinical Practice - October 15, 2018 Category: Neurology Authors: Schuster, S., Braass, H., Iking-Konert, C., Schnoor, U., Matschke, J., Gerloff, C., Thomalla, G., Magnus, T. Tags: Autoimmune diseases, Meningitis, All Clinical Neurology Review Source Type: research

Neonatal posterior cerebral artery stroke: clinical presentation, MRI findings, and outcome
AimTo report the clinical presentation, magnetic resonance imaging (MRI) findings, and follow‐up data of newborn infants with perinatal arterial ischemic stroke in the territory of the posterior cerebral artery (PCA). MethodData on 18 newborn infants from three neonatal intensive care units (11 males, seven females) with an MRI‐confirmed PCA stroke were analysed and reported. Infants were born at a mean gestational age of 38.7 weeks (SD 3.4) with a mean birthweight of 3244g (SD 850). ResultsFourteen infants presented with clinical seizures. Five of these had associated hypoxic–ischemic encephalopathy, four had hypog...
Source: Developmental Medicine and Child Neurology - January 22, 2013 Category: Child Development Authors: Niek E Aa, Jeroen Dudink, Manon J N L Benders, Paul Govaert, Henrica L M Straaten, Giorgio L Porro, Floris Groenendaal, Linda S Vries Tags: Original Article Source Type: research

A Sporadic Case of Fabry Disease Involving Repeated Fever, Psychiatric Symptoms, Headache, and Ischemic Stroke in an Adult Japanese Woman.
We describe the case of a Japanese woman with Fabry disease who presented with ischemic stroke, aseptic meningitis, and psychiatric symptoms. The patient had a mutation in intron 4 of her α-galactosidase A gene, which was not detected in her family. This case suggests that Fabry disease should be considered in young patients who exhibit central nervous system symptoms such as ischemic stroke, even if there is no family history of the condition. The episodes of aseptic meningitis and stroke experienced by our patient suggest that persistent inflammation might be the mechanism underlying Fabry disease. PMID: 26631895 [PubMed - in process]
Source: Internal Medicine - December 6, 2015 Category: Internal Medicine Tags: Intern Med Source Type: research

Administration of Uric Acid in the Emergency Treatment of Acute Ischemic Stroke
Abstract Oxidative stress is one of the main mechanisms implicated in the pathophysiology of inflammatory and neurodegenerative diseases of the central nervous system (CNS). Uric acid (UA) is the end product of purine catabolism in humans, and it is the main endogenous antioxidant in blood. Low circulating UA levels have been associated with an increased prevalence and worse clinical course of several neurodegenerative and inflammatory diseases of the CNS, including Parkinson’s disease and multiple sclerosis. Moreover, the exogenous administration of UA exerts robust neuroprotective properties in experimental m...
Source: Current Neurology and Neuroscience Reports - December 28, 2015 Category: Neuroscience Source Type: research

Clinical and Imaging Characteristics of Arteriopathy Subtypes in Children with Arterial Ischemic Stroke: Results of the VIPS Study PEDIATRICS
CONCLUSIONS: Childhood arteriopathy subtypes have some typical features that aid diagnosis. Better imaging methods, including vessel wall imaging, are needed for improved classification of focal cerebral arteriopathy of childhood.
Source: American Journal of Neuroradiology - November 15, 2017 Category: Radiology Authors: Wintermark, M., Hills, N. K., DeVeber, G. A., Barkovich, A. J., Bernard, T. J., Friedman, N. R., Mackay, M. T., Kirton, A., Zhu, G., Leiva-Salinas, C., Hou, Q., Fullerton, H. J., the VIPS Investigators Tags: PEDIATRICS Source Type: research

Acute bacterial meningitis and stroke.
Abstract INTRODUCTION: Acute bacterial meningitis remains a common disease, especially in developing countries. Although advances over the last century have improved mortality and morbidity, the neurological adverse effects remain high. Specifically, acute ischaemic stroke is a serious comorbidity that represents both disease severity and poor prognosis. This review presents the clinical connection between meningitis and stroke, and discusses the neuroinflammatory components that have direct ties between these diseases. STATE OF THE ART: Ischaemic stroke is the direct result of the inflammatory response produ...
Source: Neurologia i Neurochirurgia Polska - August 22, 2019 Category: Neurology Authors: Siegel J Tags: Neurol Neurochir Pol Source Type: research

Percheron Artery-Plus Syndrome: A Syndrome Beyond Stroke Chameleon
J Nippon Med Sch. 2021;88(4):375-379. doi: 10.1272/jnms.JNMS.2021_88-414.ABSTRACTThe artery of Percheron (AOP) is an anatomical variant of the thalamoperforating arteries. AOP occlusion can cause bilateral paramedian thalamic infarctions and is referred to as a "stroke chameleon" because it lacks the classic signs of stroke. Coexistence of AOP occlusion and other neurologic disease is rare and can cause disturbance of consciousness. A 78-year-old woman had acute onset of left limb weakness and drowsy consciousness. Brain magnetic resonance angiography (MRA) revealed acute bilateral paramedian thalamic infarctions. However,...
Source: Journal of Nippon Medical School - September 2, 2021 Category: Universities & Medical Training Authors: Fu-Yi Yang Jeng-Luen Hung Shinn-Kuang Lin Source Type: research