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Infectious Disease: Malaria
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Total 148 results found since Jan 2013.
Mortality and morbidity from infectious and non-communicable diseases in Greece during Axis/Nazi military occupation (1941-1944)
In conclusion, we found that the Axis/Nazi military occupation of Greece had considerable health effects on infectious diseases and hemorrhagic stroke mortality. Deaths ostensibly due to infectious diseases (e.g. tuberculosis or malaria), were expedited by the hunger famine of the period under investigation. With regard to the elevated mortality due to hemorrhagic stroke, we believe that the stressful events of occupation and famine have triggered increased psychosocial stress which in turn may have increased the risk of hemorrhagic stroke mortality during the period of Axis/Nazi occupation of Greece.PMID:35350253 | PMC:PM...
Source: Infezioni in Medicina - March 30, 2022 Category: Infectious Diseases Authors: Georgios Rachiotis Dimitrios Papagiannis Theodoros Dardavesis Panagiotis Behrakis Source Type: research
Nitrone-based Therapeutics for Neurodegenerative Diseases. Their use alone or in Combination with Lanthionines.
Abstract
The possibility of free radical reactions occurring in biological processes led to the development and employment of novel methods and techniques focused on determining their existence and importance in normal and pathological conditions. For this reason the use of Nitrones for spin trapping free radicals came into widespread use in the 1970s and 1980s when surprisingly the first evidence of their potent biological properties was first noted. Since then wide-spread exploration and demonstration of the potent biological properties of phenyl-tert-butylnitrone (PBN) and derivatives were shown in preclinical ...
Source: Free Radical Biology and Medicine - February 15, 2013 Category: Biology Authors: Floyd RA, Castro Faria Neto HC, Zimmerman GA, Hensley K, Towner RA Tags: Free Radic Biol Med Source Type: research
Screening of cerebral vasculopathy in sickle cell anemia children using transcranial Doppler.
Abstract
Cerebral vasculopathy exposes patients to a high risk of stroke, a major complication of sickle cell disease (SCD) associated with a high risk of death and disability. Transcranial doppler (TCD) ultrasonography used to identify SCD patients at risk of stroke may contribute to significantly reducing morbidity and mortality in these patients by indicating appropriate treatment. From March 2008 to February 2013, we conducted systematic screening for cerebral vasculopathy using TCD in 572 SCD patients (including 375 SS, 144 SC, 26 S/β(0), and 27 S/β(+) thalassemia patients) aged 1-17 years in a compre...
Source: Archives de Pediatrie - January 27, 2015 Category: Pediatrics Authors: Dorie A, Guindo A, Saro YS, Touré BA, Fané B, Dembelé AK, Diallo DA Tags: Arch Pediatr Source Type: research
Environmental Pollution: An Under-recognized Threat to Children’s Health, Especially in Low- and Middle-Income Countries
Conclusions
Patterns of disease are changing rapidly in LMICs. Pollution-related chronic diseases are becoming more common. This shift presents a particular problem for children, who are proportionately more heavily exposed than are adults to environmental pollutants and for whom these exposures are especially dangerous. Better quantification of environmental exposures and stepped-up efforts to understand how to prevent exposures that cause disease are needed in LMICs and around the globe.
To confront the global problem of disease caused by pollution, improved programs of public health monitoring and environmental protecti...
Source: EHP Research - March 1, 2016 Category: Environmental Health Authors: Web Admin Tags: Brief Communication March 2016 Source Type: research
KCA Board Member to Participate in LIVESTRONG ® Global Cancer Summit in Dublin, Ireland
FOR IMMEDIATE RELEASE Kidney Cancer Association CONTACT NAME: Carrie Konosky PHONE NUMBER: 847-655-4495 x104 EMAIL ADDRESS: ckonosky@kidneycancer.org Eric Perakslis, Kidney Cancer Association Board Member, Selected to Participate in Premiere LIVE ST...
Source: Kidney Cancer Association - July 17, 2009 Category: Urology & Nephrology Source Type: news
CNS Summit 2017 Abstracts of Poster Presentations
Conclusion: This novel technology discriminates and quantifies subtle differences in behavior and neurological impairments in subjects afflicted with neurological injury/disease. KINARM assessments can be incorporated into multi-center trials (e.g., monitoring stroke motor recovery: NCT02928393). Further studies will determine if KINARM Labs can demonstrate a clinical effect with fewer subjects over a shorter trial period.
Disclosures/funding: Dr. Stephen Scott is the inventor of KINARM and CSO of BKIN Technologies.
Multiplexed mass spectrometry assay identifies neurodegeneration biomarkers in CSF
Presenter: Chelsky...
Source: Innovations in Clinical Neuroscience - November 1, 2017 Category: Neuroscience Authors: ICNS Online Editor Tags: Assessment Tools biomarkers Cognition Current Issue Drug Development General Genetics Medical Issues Neurology Patient Assessment Psychopharmacology Scales Special Issues Supplements Trial Methodology clinical trials CNS Su Source Type: research
Cause-specific mortality in the Kombewa health and demographic surveillance systems site, rural Western Kenya from 2011-2015.
CONCLUSIONS: The analysis established the main CODs among people of all ages within the area served by the Kombewa HDSS. We hope that information generated from this study will help better address preventable deaths in the surveyed community as well as help mitigate negative health impacts in other rural communities throughout the Western Kenya region.
PMID: 29502491 [PubMed - in process]
Source: Global Health Action - March 7, 2018 Category: International Medicine & Public Health Tags: Glob Health Action Source Type: research
What Causes Facial Nerve Palsy?
Discussion
Facial nerve palsy has been known for centuries, but in 1821 unilateral facial nerve paralysis was described by Sir Charles Bell. Bell’s palsy (BP) is a unilateral, acute facial paralysis that is clinically diagnosed after other etiologies have been excluded by appropriate history, physical examination and/or laboratory testing or imaging. Symptoms include abnormal movement of facial nerve. It can be associated with changes in facial sensation, hearing, taste or excessive tearing. The right and left sides are equally affected but bilateral BP is rare (0.3%). Paralysis can be complete or incomplete at prese...
Source: PediatricEducation.org - June 3, 2019 Category: Pediatrics Authors: pediatriceducationmin Tags: Uncategorized Source Type: news
Bioinformatics analysis of a long non ‑coding RNA and mRNA regulation network in rats with middle cerebral artery occlusion based on RNA sequencing.
Bioinformatics analysis of a long non‑coding RNA and mRNA regulation network in rats with middle cerebral artery occlusion based on RNA sequencing.
Mol Med Rep. 2019 May 27;:
Authors: Duan X, Han L, Peng D, Peng C, Xiao L, Bao Q, Peng H
Abstract
Long non‑coding RNAs (lncRNAs) have been proven to be critical gene regulators of development and disease. The main aim of the present study was to elucidate the lncRNA‑mRNA regulation network in ischemic stroke induced by middle cerebral artery occlusion (MCAO) using RNA sequencing (RNA‑seq) in rats. lncRNA expression profiles were screened in brain ti...
Source: Molecular Medicine Reports - June 12, 2019 Category: Molecular Biology Tags: Mol Med Rep Source Type: research
Activated protein C in neuroprotection and malaria
Purpose of review
Activated protein C (APC) is a homeostatic coagulation protease with anticoagulant and cytoprotective activities. Focusing on APC's effects in the brain, this review discusses three different scenarios that illustrate how APC functions are intimately affecting the physiology and pathophysiology of the brain.
Recent findings
Cytoprotective APC therapy holds promise for the treatment of ischemic stroke, and a recently completed trial suggested that cytoprotective-selective 3K3A-APC reduced bleeding in ischemic stroke patients. In contrast, APC's anticoagulant activity contributes to brain bleeding as s...
Source: Current Opinion in Hematology - August 2, 2019 Category: Hematology Tags: HEMOSTASIS AND THROMBOSIS: Edited by Alvin H. Schmaier Source Type: research
Health Worker Training Is Improving Hypertension Care and Prevention in Senegal
October 31, 2019During interviews with almost 2,000 health workers and clients in Dakar, Senegal, IntraHealth International found that some 40% of health workers had not been trained to care for clients with hypertension, and 83% of clients who did not have hypertension knew no more than a single warning sign. But a 2019 evaluation reveals significant progress in under two years.The results from our 2017-2018 situational analysis uncovered gaps in hypertension care and prevention in Dakar, including insufficiencies in equipment, hypertension management skills, and patient education.Those results helped guide theBetter Hear...
Source: IntraHealth International - October 31, 2019 Category: International Medicine & Public Health Authors: mnathe Tags: Senegal Neema Noncommunicable Diseases Human Resources Management Primary Health Care Source Type: news
Albumin: Pathophysiologic basis of its role in the treatment of cirrhosis and its complications
Abstract
Since the introduction of human serum albumin as a plasma expander in the 1940s, considerable research has allowed a better understanding of its biochemical properties and potential clinical benefits. Albumin has a complex structure, which is responsible for a variety of biological functions. In disease, albumin molecule is susceptible to modifications that may alter its biological activity. During the last decades, different methods to measure albumin function have been developed. Recent studies have shown that not only albumin concentration but also albumin function is reduced in liver failure. This observation ...
Source: Hepatology - February 19, 2013 Category: Internal Medicine Authors: Rita Garcia‐Martinez, Paolo Caraceni, Mauro Bernardi, Pere Gines, Vicente Arroyo, Rajiv Jalan Tags: Liver Failure, Cirrhosis and Portal Hypertension Source Type: research
Australia faces increased risk of disease from climate change, reports find
A number of recent studies have shown a clear connection between a warming planet and increased health risksAustralia has been warned of the rising threat of dengue fever and heat stroke deaths in the wake of a study that found climate change is aiding the spread of infectious diseases around the world. The report, part-funded by the US National Science Foundation and published in Science, found that climate change is already abetting diseases in wildlife and agriculture, with humans at heightened risk from dengue fever, malaria and cholera. Wealthy countries will do much better at predicting and tackling new disease threa...
Source: Guardian Unlimited Science - August 2, 2013 Category: Science Authors: Oliver Milman Tags: theguardian.com News Climate change Environment Australia Source Type: news
Neurocognitive sequelae following hippocampal and callosal lesions associated with cerebral malaria in an immune-naive adult
We report a case of a 36-year-old immune-naive Caucasian female who sustained a brain injury with neurocognitive sequelae, after a severe bout of falciparum malaria. On admission, she was unconscious, febrile, hypoglycaemic and passing black urine. She had returned from Ghana 2 days earlier. Her initial parasite count was 22%,...
Source: Postgraduate Medical Journal - October 15, 2013 Category: Journals (General) Authors: Laverse, E., Nashef, L., Brown, S. Tags: Immunology (including allergy), Drugs: infectious diseases, Travel medicine, Tropical medicine (infectious diseases), Epilepsy and seizures, Stroke, Memory disorders (psychiatry), Adult intensive care, Epidemiology, Diabetes, Metabolic disorders Images Source Type: research
