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Condition: Sleep Disorders
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Total 140 results found since Jan 2013.

Sleep biology discovery could lead to new insomnia treatments that don ’t target the brain
UCLA scientists report the first evidence that a gene outside the brain controls the ability to rebound from sleep deprivation — a surprising discovery that could eventually lead to greatly improved treatments for insomnia and other sleep disorders that do not involve getting a drug into the brain.The scientists report that increasing the level of Bmal1 — a critical master gene that regulates sleep patterns — in skeletal muscle makes mice resistant to sleep deprivation.“When we first saw the importance of the muscle, we were surprised,” said senior author Ketema Paul, UCLA associate professor of integrative biolo...
Source: UCLA Newsroom: Health Sciences - August 10, 2017 Category: Universities & Medical Training Source Type: news

Sleep-Disordered Breathing
ABSTRACT: Purpose of Review: Sleep-disordered breathing encompasses a broad spectrum of sleep-related breathing disorders, including obstructive sleep apnea (OSA), central sleep apnea, as well as sleep-related hypoventilation and hypoxemia. Diagnostic criteria have been updated in the International Classification of Sleep Disorders, Third Edition and the American Academy of Sleep Medicine Manual for Scoring Sleep and Associated Events. Neurologic providers should have basic knowledge and skills to identify at-risk patients, as these disorders are associated with substantial morbidity, the treatment of which is largely reve...
Source: CONTINUUM: Lifelong Learning in Neurology - August 1, 2017 Category: Neurology Tags: Review Articles Source Type: research

Targeted Memory Reactivation During Sleep, But Not Wake, Enhances Sensorimotor Skill Performance: A Pilot Study.
In conclusion, this pilot study indicates that it is feasible to influence sensorimotor skill performance through TMR during sleep and may serve as a future adjunct to physical rehabilitation. Future studies will aim to confirm the present results with a larger sample size as well as investigate the effects of TMR during sleep on older adults both with and without a history of stroke. PMID: 28644921 [PubMed - as supplied by publisher]
Source: Journal of Motor Behavior - June 24, 2017 Category: Neurology Tags: J Mot Behav Source Type: research

Sleep Deprivation Is Killing You (And Making You Fat In The Process)
The next time you tell yourself that you'll sleep when you're dead, realize that you're making a decision that can make that day come much sooner. Pushing late into the night is a health and productivity killer. According to the Division of Sleep Medicine at the Harvard Medical School, the short-term productivity gains from skipping sleep to work are quickly washed away by the detrimental effects of sleep deprivation on your mood, ability to focus, and access to higher-level brain functions for days to come. The negative effects of sleep deprivation are so great that people who are drunk outperform those lacking sleep. Why...
Source: Healthy Living - The Huffington Post - June 24, 2017 Category: Consumer Health News Source Type: news

Poor Sleep Hygiene Is Killing You And Your Career
The next time you tell yourself that you'll sleep when you're dead, realize that you're making a decision that can make that day come much sooner. Pushing late into the night is a health and productivity killer. According to the Division of Sleep Medicine at the Harvard Medical School, the short-term productivity gains from skipping sleep to work are quickly washed away by the detrimental effects of sleep deprivation on your mood, ability to focus, and access to higher-level brain functions for days to come. The negative effects of sleep deprivation are so great that people who are drunk outperform those lacking sleep. Why...
Source: Healthy Living - The Huffington Post - April 22, 2017 Category: Consumer Health News Source Type: news

Executive Function Is Associated With Off-Line Motor Learning in People With Chronic Stroke
Conclusions: This is the first study to demonstrate that better performance on an executive function test of attention and set-shifting predicts a higher magnitude of off-line motor learning in individuals with chronic stroke. This emphasizes the need to consider attention and set-shifting abilities of individuals following stroke as these abilities are associated with motor learning. This in turn could affect learning of activities of daily living and impact functional recovery following stroke. Video Abstract available for more insights from the authors (see Video, Supplemental Digital Content 1, http://links.lww.com/JNPT/A166 ).
Source: Journal of Neurologic Physical Therapy - March 25, 2017 Category: Physiotherapy Tags: Research Articles Source Type: research

How to Boost Your Stem Cells
A California man named Kris Boesen was completely paralyzed after breaking his neck in a terrible car crash last March. But now he can brush his teeth and hug his family again… He's even started to regain sensation in his legs. And it's all because of a simple procedure he underwent about a month after his accident: stem cell therapy. During Kris' procedure, researchers at the University of Southern California injected 10 million stem cells into his spinal cord. Within two weeks, he could wiggle his fingers. Three months later, he was able to feed himself, write his name and operate his wheelchair. His re...
Source: Al Sears, MD Natural Remedies - March 23, 2017 Category: Complementary Medicine Authors: Al Sears Tags: Anti-Aging Source Type: news

Executive Function Is Associated With Off-Line Motor Learning in People With Chronic Stroke.
CONCLUSIONS: This is the first study to demonstrate that better performance on an executive function test of attention and set-shifting predicts a higher magnitude of off-line motor learning in individuals with chronic stroke. This emphasizes the need to consider attention and set-shifting abilities of individuals following stroke as these abilities are associated with motor learning. This in turn could affect learning of activities of daily living and impact functional recovery following stroke.Video Abstract available for more insights from the authors (see Video, Supplemental Digital Content 1, http://links.lww.com/JNPT...
Source: Physical Therapy - March 2, 2017 Category: Physiotherapy Authors: Al-Dughmi M, Al-Sharman A, Stevens S, Siengsukon CF Tags: J Neurol Phys Ther Source Type: research

The Four Questions You Should Ask Yourself About Brain Health
I don’t watch much TV, and when I do, I rarely pay attention to commercials. But a new ad caught my eye the other day: in it, a middle-aged accountant talks frankly about his passion for his work. Numbers, he says, just come naturally to him, and he feels like his brain is firing on all cylinders when he’s working at something he loves. Then, the CEO of AARP walks into the frame and announces a new website featuring quizzes, games, and other applications designed to promote the brain health of older Americans. Having spent a good portion of my career working to make brain health as well-known a term as heart h...
Source: Science - The Huffington Post - February 3, 2017 Category: Science Source Type: news

CNS Summit 2016 Abstracts of Poster Presentations
Conclusion: Subjects with acutely exacerbated schizophrenia who were eligible for discharge from the inpatient setting and who completed the study demonstrated high rates of adherence using the mobile AI application. Subjects were able to easily use the technology. Use of the platform did not appear to increase the dropout rate. This study demonstrates the feasibility of using AI platforms to ensure high adherence, provide reliable adherence data, and rapidly detect nonadherence in CNS trials. Disclosures/funding: Adam Hanina and Laura Shafner are employees of AiCure, New York, New York, and consultants to Takeda. Xinxin D...
Source: Innovations in Clinical Neuroscience - February 1, 2017 Category: Neuroscience Authors: ICN Online Editor Tags: Assessment Tools biomarkers Cognition Current Issue Devices Drug Development Evaluations Genetics Medical Issues Neurology Patient Assessment Proceedings Psychiatry Psychopharmacology Scales Supplements Technology Trial M Source Type: research

Stroke Epidemiology and Risk Factor Management
This article reviews the current recommendations for the management of each of these modifiable risk factors. Recent Findings: It has been documented that some blood pressure medications may increase variability of blood pressure and ultimately increase the risk for stroke. Stroke prevention typically includes antiplatelet therapy (unless an indication for anticoagulation exists), so the most recent evidence supporting use of these drugs is reviewed. In addition, emerging risk factors, such as obstructive sleep apnea, electronic cigarettes, and elevated lipoprotein (a), are discussed. Summary: Overall, secondary stroke p...
Source: CONTINUUM: Lifelong Learning in Neurology - February 1, 2017 Category: Neurology Tags: Review Articles Source Type: research

Patient, Doctor, and the Data: Emergence of the Third Player
Amith Vikramr The conventional model of medicine had only two players. The doctor alone had access to all medical information and his encounter with the patient was the only way to obtain health-related information. The dawn of the information age led to a change in the dynamics in this relationship. A consumerist model of healthcare has emerged where doctors partner with patients in managing the patient’s illness. The advances in systems biology, big data and consumer health care electronics will add patient data as a new element to the patient-physician interface. In the next decade, individual patients will generate ...
Source: Society for Participatory Medicine - December 6, 2016 Category: Journals (General) Authors: Nanette Mattox Tags: Newsletter e-patient movement empowered patient Moral Injury participatory medicine Patient Participation Source Type: news

Are You Getting Older - Or Are You Getting Sleep Apnea?
By Brandon R. Peters, MD As my 81-year-old grandma likes to remind me on occasion, "It's hell to get old." More than a nuisance, the cumulative decline that comes with aging can significantly compromise one's quality of life and health. What if some of the problems so often associated with growing older didn't need to occur? Better yet, what if some of these physical and mental impairments could be reversed? Consider the role of sleep apnea as an unexpected contributor to many ailments erroneously attributed to aging and the reversals possible with effective treatment. Sleep Changes with Age It is clear that sleep chang...
Source: Healthy Living - The Huffington Post - November 15, 2016 Category: Consumer Health News Source Type: news