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Total 750 results found since Jan 2013.

Carotid free-floating thrombus in COVID-19: a cerebrovascular disorder of cytokine storm-related immunothrombosis
CONCLUSIONS: COVID-19-induced immunothrombosis possibly played a significant pathogenic role in CFFT.PMID:36807242 | DOI:10.1007/s10072-023-06682-3
Source: Atherosclerosis - February 22, 2023 Category: Cardiology Authors: Umberto Pensato Stefano Forlivesi Mauro Gentile Michele Romoli Lorenzo Muccioli Francesca Ambrosi Maria Pia Foschini Carmine Gallo Maria Sandra Ballestrazzi Paolo Teutonico Gianluca Faggioli Mauro Gargiulo Simone Galluzzo Francesco Taglialatela Luigi Simo Source Type: research

A Retrospective Observational Study of Neurological Manifestations in COVID-19 (SON-CoV)
Conclusion: CNS symptoms of COVID-19 are more common than PNS symptoms. Stroke is the most frequent (46%) COVID-CNS symptom, which occurs in people of age above 35 years and is associated with high mortality.PMID:37355862 | DOI:10.5005/japi-11001-0107
Source: Journal of the Association of Physicians of India - June 25, 2023 Category: General Medicine Authors: Neetu Ramrakhiani Neeraj Bhutani Deepak Chaudhary Pooja Parab Karni Singh Priya Agrawal Vikas Gupta Source Type: research

E-241 Clinicopathologic analysis of COVID-19 associated thrombi in the setting of large vessel occlusion: a prospective case control study
ConclusionThrombi retrieved from COVID-19 positive stroke patients demonstrated RBC predominance. This finding requires further investigation using appropriate immunohistochemical techniques in a larger cohort of patients.Abstract E-241 Figure 1Abstract E-241 Figure 2COVID-19 positive patient thrombus; stained with H&E demonstrating predominantly RBCs (solid yellow arrow) with interspersed fibrin (solid black arrow) and platelets. Original magnification X100Disclosures R. Floresca: None. F. Sheriff: None. J. Lavezo: None. M. Chaudhury: None. G. Colina: None. R. Regenhardt: None. V. Gupta: None. G. Rodriguez: None. A. Maud: None.
Source: Journal of NeuroInterventional Surgery - July 30, 2023 Category: Neurosurgery Authors: Floresca, R., Sheriff, F., Lavezo, J., Chaudhury, M., Colina, G., Regenhardt, R., Gupta, V., Rodriguez, G., Maud, A. Tags: SNIS 20th annual meeting electronic poster abstracts Source Type: research

COVID-19 related strokes, other neurological impact under study
(Medical College of Georgia at Augusta University) Traditional stroke treatments like clot-dissolving tPA and surgical removal of big clots in the brain are good choices as well when the stroke results from SARS-CoV-2 infection, investigators report.
Source: EurekAlert! - Infectious and Emerging Diseases - May 20, 2020 Category: Infectious Diseases Source Type: news

Severe acute respiratory syndrome coronavirus 2 is penetrating to dementia research.
Abstract 1. Introduction Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) causes coronavirus infectious disease 2019 (COVID-19), which was first reported in Wuhan, China, in late December, 2019. Despite the tremendous efforts to control the disease, SARS-CoV-2 has infected 1,5 million people and caused the death of more than a hundred thousand people across the globe as of writing. Recently, Mao et al. [1] investigated the penetration potential of SARS-CoV-2 into the central nervous system in 214 patients. They reported that 36.4% of the patients had some neurologic findings which are ranged from nonsp...
Source: Current Neurovascular Research - May 21, 2020 Category: Neurology Authors: Bostanciklioglu M, Temiz E Tags: Curr Neurovasc Res Source Type: research

Neurologic aspects of covid-19: a concise review.
In conclusion, nervous system symptoms can be observed during SARS-CoV2 infection of which headache and smell and taste disturbance are the main symptoms reported. Cerebrovascular complications can complicate the course of COVID-19 in apparently low-risk patients. GBS is a life-threatening manifestation of COVID-19. PMID: 32532937 [PubMed - as supplied by publisher]
Source: Infezioni in Medicina - June 14, 2020 Category: Infectious Diseases Tags: Infez Med Source Type: research

Neurological consultations and diagnoses in a large, dedicated COVID-19 university hospital
Conclusions: Most neurological consultations in a COVID-19-dedicated hospital were requested for severe conditions that could have an impact on the outcome. First-line doctors should be able to recognize neurological symptoms; neu rologists are important members of the medical team in COVID-19 hospital care.RESUMO Introdu ção: Mais de um terço dos pacientes com COVID-19 apresentam sintomas neurológicos que variam de anosmia a AVC e encefalopatia. Além disso, doenças neurológicas prévias podem exigir tratamento especial e estar associadas a piores desfechos. Não obstante, o papel dos neurologistas na COVID-1 9 é p...
Source: Arquivos de Neuro-Psiquiatria - September 2, 2020 Category: Neurology Source Type: research

Neurological reasons for consultation and hospitalization during the COVID-19 pandemic
ConclusionNeurological disturbances represent a significant and severe burden in COVID-19 patients, and they can be the presenting condition that leads to the diagnosis of the viral infection in a high percentage of patients. Evidence of direct viral mechanisms was scarce, but the pathogenesis of the diverse manifestations remains enigmatic.
Source: Neurological Sciences - October 16, 2020 Category: Neurology Source Type: research

UCLA researchers study genetics ’ role in COVID-19 susceptibility, severity
“One of the most troubling things about COVID-19 is that we have a limited ability to predict how sick a specific individual will get,” said Dr. Daniel Geschwind.Geschwind is the MacDonald Distinguished Professor in Human Genetics at theDavid Geffen School of Medicine at UCLA and a member of theEli and Edythe Broad Center of  Regenerative Medicine and Stem Cell Research at UCLA. And he ’s part of a team of UCLA scientists conducting research to learn why certain people get sick from the virus that causes COVID-19 — and why others don’t.Millions of people around the world have been infected with SARS-CoV-2, the v...
Source: UCLA Newsroom: Health Sciences - October 26, 2020 Category: Universities & Medical Training Source Type: news

Neuronal and Cerebrovascular Complications in Coronavirus Disease 2019
Coronavirus disease 2019 (COVID-19) is a pandemic disease resulting from severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) infection, primarily in the respiratory tract. This pandemic disease has affected the entire world, and the pathobiology of this disease is not yet completely known. The Interactions of SARS-CoV-2 proteins with different cellular components in the host cell may be necessary for understanding the disease mechanism and identifying crucial pharmacological targets in COVID-19. Studies have suggested that the effect of SARS-CoV-2 on other organs, including the brain, maybe critical for understand...
Source: Frontiers in Pharmacology - November 20, 2020 Category: Drugs & Pharmacology Source Type: research

Neurological Associations of COVID-19 —Do We Know Enough: A Tertiary Care Hospital Based Study
This study will discuss the detailed systematically evaluated clinical profile and relevant investigations and outcome of 14 laboratory confirmed SARS-CoV-2 positive patients presenting with neurological signs and symptoms. The patients were further categorized into confirmed, probable, and possible neurological associations. The probable association was found in meningoencephalitis (n = 4), stroke (n = 2), Guillain-Barré syndrome (n = 1), and anosmia (n = 1). The other six patients had coexisting neurological diseases with SARS-CoV-2. One patient with a large artery stroke succumbed to the illness due to respiratory comp...
Source: Frontiers in Neurology - November 24, 2020 Category: Neurology Source Type: research

High Prevalence of Deep Venous Thrombosis in Non-Severe COVID-19 Patients Hospitalized for a Neurovascular Disease
Conclusion: Despite thromboprophylaxis, systematic bedside DUS showed a high prevalence (38.5%) of asymptomatic DVT in non-severe COVID-19 patients suffering from a neurovascular disease. In the absence of a reliable marker of DVT, we suggest that this non-invasive investigation could be an interesting tool to monitor peripheral venous thrombotic complications in such patients.Cerebrovasc Dis Extra 2020;10:174 –180
Source: Cerebrovascular Diseases Extra - December 7, 2020 Category: Neurology Source Type: research

Does a history of cardiovascular disease or cancer affect mortality after SARS-CoV-2 infection?
Abstract BACKGROUND: Cardiovascular disease and cancer have been described as possible risk factors for COVID-19 mortality. The purpose of this study was to investigate whether a history of cardiovascular disease or cancer affects the risk of dying after a COVID-19 diagnosis in Norway. MATERIAL AND METHOD: Data were compiled from the Norwegian Surveillance System for Communicable Diseases, the Norwegian Cardiovascular Disease Registry and the Cancer Registry of Norway. Univariable and multivariable regression models were used to calculate both relative and absolute risk. RESULTS: In the first half of 20...
Source: Tidsskrift for den Norske Laegeforening - February 2, 2021 Category: General Medicine Authors: Kvåle R, Bønaa KH, Forster R, Gravningen K, Júlíusson PB, Myklebust TÅ Tags: Tidsskr Nor Laegeforen Source Type: research