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Condition: Anemia
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Total 684 results found since Jan 2013.

Daily Aspirin No Longer Recommended To Prevent Heart Attacks In Older Adults
(CNN) — If you’re a healthy older adult looking for ways to reduce your risk of heart attack and stroke, don’t turn to that age-old standby: daily low-dose aspirin. It’s no longer recommended as a preventative for older adults who don’t have a high risk or existing heart disease, according to guidelines announced Sunday by the American College of Cardiology and the American Heart Association. “For the most part, we are now much better at treating risk factors such as hypertension, diabetes and especially high cholesterol,” said North Carolina cardiologist Dr. Kevin Campbell, who wa...
Source: WBZ-TV - Breaking News, Weather and Sports for Boston, Worcester and New Hampshire - March 18, 2019 Category: Consumer Health News Authors: Health – CBS Boston Tags: Health News aspirin CNN Source Type: news

Cognitive Function in Sickle Cell Disease Across Domains, Cerebral Infarct Status, and the Lifespan: A Meta-Analysis
ConclusionIndividuals with SCD are at risk for cognitive deficits across domains, infarct status, and the lifespan. More research is necessary to determine unbiased effects for cognitive function in adults with SCD.
Source: Journal of Pediatric Psychology - May 3, 2019 Category: Pediatrics Source Type: research

Bleeding in the Elderly: Risk Factors and Impact on Clinical Outcomes After an Acute Coronary Syndrome, a Sub-study of the Randomized ANTARCTIC Trial
ConclusionsClinically relevant bleeding events were observed in one out of five elderly patients undergoing stenting for an ACS and were strongly associated with further stroke occurrence. Rather than the antiplatelet therapy, comorbidities and an age>  85 years predicted bleeding outcomes in this elderly population.Clinical Trial RegistrationClinicaltrials.gov identifier: NCT01538446.https://www.clinicaltrials.gov.
Source: American Journal of Cardiovascular Drugs - June 30, 2021 Category: Cardiology Source Type: research

Transfusion thresholds for guiding red blood cell transfusion
CONCLUSIONS: Transfusion at a restrictive haemoglobin concentration decreased the proportion of people exposed to RBC transfusion by 41% across a broad range of clinical contexts. Across all trials, no evidence suggests that a restrictive transfusion strategy impacted 30-day mortality, mortality at other time points, or morbidity (i.e. cardiac events, myocardial infarction, stroke, pneumonia, thromboembolism, infection) compared with a liberal transfusion strategy. Despite including 17 more randomised trials (and 8846 participants), data remain insufficient to inform the safety of transfusion policies in important and sele...
Source: Cochrane Database of Systematic Reviews - December 21, 2021 Category: General Medicine Authors: Jeffrey L Carson Simon J Stanworth Jane A Dennis Marialena Trivella Nareg Roubinian Dean A Fergusson Darrell Triulzi Carolyn Dor ée Paul C H ébert Source Type: research

Medicare Bundled Payment Policy on Anemia Care, Major Adverse Cardiovascular Events, and Mortality among Adults Undergoing Hemodialysis
CONCLUSIONS: The Medicare reimbursement policy and Food and Drug Administration-recommended erythropoietin-stimulating agent dosing changes were associated with lower erythropoietin-stimulating agent use and lower hemoglobin levels. These changes in anemia care were associated with lower risks of major adverse cardiovascular event, stroke, mortality, and heart failure but higher risk of acute myocardial infarction among adults receiving hemodialysis.PMID:35589388 | DOI:10.2215/CJN.14361121
Source: Clinical Journal of the American Society of Nephrology : CJASN - May 19, 2022 Category: Urology & Nephrology Authors: Haesuk Park Raj Desai Xinyue Liu Steven M Smith Juan Hincapie-Castillo Linda Henry Amie Goodin Saraswathi Gopal Carl J Pepine Raj Mohandas Source Type: research

A Retrospective Observational Study of Neurological Manifestations in COVID-19 (SON-CoV)
Conclusion: CNS symptoms of COVID-19 are more common than PNS symptoms. Stroke is the most frequent (46%) COVID-CNS symptom, which occurs in people of age above 35 years and is associated with high mortality.PMID:37355862 | DOI:10.5005/japi-11001-0107
Source: Journal of the Association of Physicians of India - June 25, 2023 Category: General Medicine Authors: Neetu Ramrakhiani Neeraj Bhutani Deepak Chaudhary Pooja Parab Karni Singh Priya Agrawal Vikas Gupta Source Type: research

Stem Cells for Cell-Based Therapies
The world of stem cells We know the human body comprises many cell types (e.g., blood cells, skin cells, cervical cells), but we often forget to appreciate that all of these different cell types arose from a single cell—the fertilized egg. A host of sequential, awe-inspiring events occur between the fertilization of an egg and the formation of a new individual: Embryonic stem (ES) cells are also called totipotent cells. The first steps involve making more cells by simple cell division: one cell becomes two cells; two cells become four cells, etc. Each cell of early development is undifferentiated; that is, it is...
Source: ActionBioscience - December 28, 2012 Category: Science Authors: Ali Hochberg Source Type: news

Usefulness of Hemoglobin Level to Predict Long-term Mortality in Patients With Asymptomatic Carotid Narrowing by Ultrasonography
In this study, the authors tested the long-term influence of hemoglobin level on all-cause and cardiovascular mortality in patients with atherosclerotic disease. They prospectively studied 1065 of 1286 consecutive patients identified with asymptomatic carotid stenosis. Of these, 275 patients (25.8%) died during a median follow-up of 6.2 years, corresponding to 5551 person-years. Continuous measures of hemoglobin displayed a significant inverse effect on all-cause mortality and cardiovascular mortality, with adjusted hazard ratio (HR) for increase of 1 standard deviation of hemoglobin of 0.73 (95% confidence interval [CI], 0.64-0.83; P
Source: Journal of Vascular Surgery - May 29, 2013 Category: Surgery Authors: G. Goliasch, M. Schillinger, F.J. Mayer Florian Tags: Abstracts Source Type: research

Physical comorbidity and its relevance on mortality in schizophrenia: a naturalistic 12-year follow-up in general hospital admissions.
Authors: Schoepf D, Uppal H, Potluri R, Heun R Abstract Schizophrenia is a major psychotic disorder with significant comorbidity and mortality. Patients with schizophrenia are said to suffer more type-2 diabetes mellitus (T2DM) and diabetogenic complications. However, there is little consistent evidence that comorbidity with physical diseases leads to excess mortality in schizophrenic patients. Consequently, we investigated whether the burden of physical comorbidity and its relevance on hospital mortality differed between patients with and without schizophrenia in a 12-year follow-up in general hospital admissions....
Source: European Archives of Psychiatry and Clinical Neuroscience - August 15, 2013 Category: Psychiatry Tags: Eur Arch Psychiatry Clin Neurosci Source Type: research

Transcranial doppler ultrasonography in children with sickle cell anemia: Clinical and laboratory correlates for elevated blood flow velocities
ConclusionsLow hematocrit, low hemoglobin concentration, young age, and low arterial oxygen desaturation predicted elevated cerebral blood flow velocities and, invariably, increased stroke risk, in children with SCA. Children who exhibit these features should be given high priority for TCD examination in the setting of limited resources. © 2013 Wiley Periodicals, Inc. J Clin Ultrasound 00:XX–XX, 2013; Published online in Wiley Online Library (www.wileyonlinelibrary.com). DOI: 10.1002/jcu.20XXX © 2013 Wiley Periodicals, Inc. J Clin Ultrasound, 2013
Source: Journal of Clinical Ultrasound - October 26, 2013 Category: Radiology Authors: IkeOluwa Lagunju, Olugbemiro Sodeinde, Biobele Brown, Felix Akinbami, Babatunde Adedokun Tags: Research Article Source Type: research

Clinical Outcomes of Erythropoietin Use in Heart Failure Patients With Anemia of Chronic Kidney Disease
Conclusions: We found that in CRAS patients, EPO use was associated with increased risk of mortality and a trend toward increased cardiovascular events. Therefore, clinicians considering EPO use in CRAS patients should assess whether any potential benefits outweigh the risks of use.
Source: Journal of Cardiac Failure - February 13, 2014 Category: Cardiology Authors: Cynthia A. Jackevicius, Cindy Shutieng Fan, Alberta Warner Tags: Clinical Investigations Source Type: research