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Total 125554 results found since Jan 2013.

Atrial Fibrillation Is Associated With a Worse 90-Day Outcome Than Other Cardioembolic Stroke Subtypes Clinical Sciences
Conclusions— AF is associated with an unfavorable 90-day outcome among patients with a CES independent of established risk factors and initial stroke severity. This suggests that AF-specific mechanisms affect CES severity and functional status after CES. If confirmed in future studies, further investigation into the underlying pathophysiological mechanisms may provide novel avenues to AF detection and treatment.
Source: Stroke - May 22, 2016 Category: Neurology Authors: Henninger, N., Goddeau, R. P., Karmarkar, A., Helenius, J., McManus, D. D. Tags: Atrial Fibrillation, Etiology, Ischemic Stroke Clinical Sciences Source Type: research

External Validation of the ASTRAL and DRAGON Scores for Prediction of Functional Outcome in Stroke Clinical Sciences
Conclusions— The ASTRAL and DRAGON scores show an acceptable predictive performance. ASTRAL does not require imaging-data and therefore may have an advantage for the use in prehospital patient assessment. Prospective studies of both scores evaluating the impact of their use on patient outcomes after intravenous thrombolysis and endovascular therapy are needed.
Source: Stroke - May 22, 2016 Category: Neurology Authors: Cooray, C., Mazya, M., Bottai, M., Dorado, L., Skoda, O., Toni, D., Ford, G. A., Wahlgren, N., Ahmed, N. Tags: Prognosis, Cerebrovascular Disease/Stroke, Ischemic Stroke Clinical Sciences Source Type: research

Determinants and Outcomes of Stroke Following Percutaneous Coronary Intervention by Indication Clinical Sciences
Conclusions— Hemorrhagic and ischemic stroke complications are uncommon, but serious complications can occur after PCI and are independently associated with worse mortality and major adverse cardiovascular events outcomes in both the elective and acute coronary syndrome setting irrespective of stroke type. Our study provides a better understanding of the risk factors and prognosis of stroke after PCI by procedure type, allowing physicians to provide more informed advice around stroke risk after PCI and counsel patients and their families around outcomes if such neurological complications occur.
Source: Stroke - May 22, 2016 Category: Neurology Authors: Myint, P. K., Kwok, C. S., Roffe, C., Kontopantelis, E., Zaman, A., Berry, C., Ludman, P. F., de Belder, M. A., Mamas, M. A., on behalf of the British Cardiovascular Intervention Society and the National Institute for Cardiovascular Outcomes Research Tags: Percutaneous Coronary Intervention, Intracranial Hemorrhage, Ischemic Stroke Clinical Sciences Source Type: research

First-Ever Stroke and Transient Ischemic Attack Incidence and 30-Day Case-Fatality Rates in a Population-Based Study in Argentina Brief Reports
Conclusions— This study provides the first prospective population-based stroke and TIA incidence and case-fatality estimate in Argentina. First-ever stroke incidence was lower than that reported in previous Latin-American studies, but first-ever TIA incidence was higher. Thirty-day case-fatality rates were similar to those of other population-based Latin-American studies.
Source: Stroke - May 22, 2016 Category: Neurology Authors: Bahit, M. C., Coppola, M. L., Riccio, P. M., Cipriano, L. E., Roth, G. A., Lopes, R. D., Feigin, V. L., Borrego Guerrero, B., De Martino, M., Diaz, A., Ferrante, D., Funaro, F., Lavados, P., Lewin, M. L., Lopez, D. H., Macarrone, P., Marciello, R., Marino Tags: Epidemiology, Race and Ethnicity, Mortality/Survival, Cerebrovascular Disease/Stroke, Transient Ischemic Attack (TIA) Brief Reports Source Type: research

Low Circulating Acute Brain-Derived Neurotrophic Factor Levels Are Associated With Poor Long-Term Functional Outcome After Ischemic Stroke Brief Reports
Conclusions— Circulating concentrations of BDNF protein are lowered in the acute phase of ischemic stroke, and low levels are associated with poor long-term functional outcome. Further studies are necessary to confirm these associations and to determine the predictive value of BDNF in stroke outcomes.
Source: Stroke - June 26, 2016 Category: Neurology Authors: Stanne, T. M., Aberg, N. D., Nilsson, S., Jood, K., Blomstrand, C., Andreasson, U., Blennow, K., Zetterberg, H., Isgaard, J., Svensson, J., Jern, C. Tags: Biomarkers, Etiology, Ischemic Stroke Brief Reports Source Type: research

Association of Major Depressive Episodes With Stroke Risk in a Prospective Study of 0.5 Million Chinese Adults Clinical Sciences
Conclusions— Findings from this large prospective study suggest that the presence of MDE is a risk factor for stroke, especially in smokers.
Source: Stroke - August 21, 2016 Category: Neurology Authors: Sun, J., Ma, H., Yu, C., Lv, J., Guo, Y., Bian, Z., Yang, L., Chen, Y., Shen, H., Chen, Z., Hu, Z., Li, L., on behalf of the China Kadoorie Biobank Collaborative Group Tags: Mental Health, Cerebrovascular Disease/Stroke Clinical Sciences Source Type: research

The effect of water-based exercises on balance in persons post-stroke: a randomized controlled trial.
This study examined the effect of water-based exercises compared to land-based exercises on the balance of people with sub-acute stroke. METHODS: In this single-blind randomized controlled study, 32 patients with first-time stroke discharged from inpatient rehabilitation at West Park Healthcare Centre were recruited. Participants were randomized into W (water-based + land; n = 17) or L (land only; n = 15) exercise groups. Both groups attended therapy two times per week for six weeks. Initial and progression protocols for the water-based exercises (a combination of balance, stretching, and strengthening and endur...
Source: Topics in Stroke Rehabilitation - November 2, 2016 Category: Neurology Authors: Chan K, Phadke CP, Stremler D, Suter L, Pauley T, Ismail F, Boulias C Tags: Top Stroke Rehabil Source Type: research

Changes in caregiver burden among informal caregivers of stroke patients in Mongolia.
This study aimed to define the changes in CGB in the first year of caregiving among the caregivers of stroke patients and to identify associated factors. METHODS: A prospective, multi-centered observational study was conducted in nine public hospitals in Mongolia. We used the Montgomery CGB Scale for assessing CGB, and repeated the assessment after 1 year. Stroke patient characteristics were included in the analyses. Multinomial logistic regressions were conducted to analyze changes in CGB. RESULTS: A paired t-test analysis revealed that demand burden increased (from 12.61 to 11.50, p = 0.034), whereas stress ...
Source: Topics in Stroke Rehabilitation - January 17, 2017 Category: Neurology Authors: Chuluunbaatar E, Pu C, Chou YJ Tags: Top Stroke Rehabil Source Type: research

The effect of self-management education following mild stroke: an exploratory randomized controlled trial.
CONCLUSIONS: The results did not identify a positive effect that would support the use of the CDSMP with individual's post-mild stroke; however, the generalizability of these results is limited secondary to several limitations in this exploratory study. PMID: 28191861 [PubMed - as supplied by publisher]
Source: Topics in Stroke Rehabilitation - February 12, 2017 Category: Neurology Authors: Wolf TJ, Spiers MJ, Doherty M, Leary EV Tags: Top Stroke Rehabil Source Type: research

Coexistent Sickle Cell Disease Has No Impact on the Safety or Outcome of Lytic Therapy in Acute Ischemic Stroke Clinical Sciences
Conclusions—Coexistent SCD had no significant impact on the safety or outcome of thrombolytic therapy in acute ischemic stroke. Although the sample size is relatively small, these data suggest that adults with SCD and acute ischemic stroke should be treated with thrombolysis, if they otherwise qualify. Addition studies, however, should track the intracranial hemorrhage rate and provide information on other SCD-related care such as transfusion.
Source: Stroke - February 26, 2017 Category: Neurology Authors: Robert J. Adams, Margueritte Cox, Shelly D. Ozark, Julie Kanter, Phillip J. Schulte, Ying Xian, Gregg C. Fonarow, Eric E. Smith, Lee H. Schwamm Tags: Ischemic Stroke, Transient Ischemic Attack (TIA) Original Contributions Source Type: research

How does sex affect the care dependency risk one year after stroke? A study based on claims data from a German health insurance fund.
DISCUSSION: It may be assumed that women have a higher risk of becoming care-dependent after stroke than men because they are older and suffer more often from geriatric conditions such as urinary incontinence at onset of stroke. Preventive strategies should therefore focus on geriatric conditions in order to reduce the post-stroke care dependency risk for women. PMID: 28330419 [PubMed - as supplied by publisher]
Source: Topics in Stroke Rehabilitation - March 22, 2017 Category: Neurology Authors: Schnitzer S, Deutschbein J, Nolte CH, Kohler M, Kuhlmey A, Schenk L Tags: Top Stroke Rehabil Source Type: research

Promoting physical activity after stroke via self-management: a feasibility study.
CONCLUSION: Self-management appears to be feasible and has the potential to increase physical activity in people with mild disability after stroke. A Phase II randomized trial is warranted. PMID: 28335690 [PubMed - as supplied by publisher]
Source: Topics in Stroke Rehabilitation - March 23, 2017 Category: Neurology Authors: Preston E, Dean CM, Ada L, Stanton R, Brauer S, Kuys S, Waddington G Tags: Top Stroke Rehabil Source Type: research

The FAST-ED App: A Smartphone Platform for the Field Triage of Patients With Stroke Clinical Sciences
Conclusions—The FAST-ED smartphone application has great potential to improve the triage of patients with acute ischemic stroke, as it seems capable to optimize resources, reduce hospital arrivals times, and maximize the use of both intravenous tissue-type plasminogen activator and endovascular treatment ultimately leading to better clinical outcomes. Future field studies are needed to properly evaluate the impact of this tool in stroke outcomes and resource utilization.
Source: Stroke - April 24, 2017 Category: Neurology Authors: Raul G. Nogueira, Gisele S. Silva, Fabricio O. Lima, Yu-Chih Yeh, Carol Fleming, Daniel Branco, Arthur H. Yancey, Jonathan J. Ratcliff, Robert Keith Wages, Earnest Doss, Mehdi Bouslama, Jonathan A. Grossberg, Diogo C. Haussen, Teppei Sakano, Michael R. Fr Tags: Quality and Outcomes, Cerebrovascular Procedures, Ischemic Stroke Original Contributions Source Type: research

Clinical and psychosocial predictors of exceeding target length of stay during inpatient stroke rehabilitation.
CONCLUSIONS: Findings suggest that social and stroke-specific factors may be helpful to adjust LOS expectations and promote efficient resource allocation. This exploratory study was limited to findings from one inpatient rehabilitation hospital. Cross-validation of results using data-sets from multiple rehabilitation hospitals across Ontario is recommended. PMID: 28486861 [PubMed - as supplied by publisher]
Source: Topics in Stroke Rehabilitation - May 9, 2017 Category: Neurology Authors: Lai W, Buttineau M, Harvey JK, Pucci RA, Wong APM, Dell'Erario L, Bosnyak S, Reid S, Salbach NM Tags: Top Stroke Rehabil Source Type: research

Serum Insulin-Like Growth Factor 1 and the Risk of Ischemic Stroke Clinical Sciences
We examined prospectively the association between serum IGF-1 levels and incident ischemic stroke.Methods—We measured serum IGF-1 levels in 757 elderly individuals (mean age 79±5, 62% women), free of prevalent stroke, from the Framingham original cohort participants at the 22nd examination cycle (1990–1994) and were followed up for the development of ischemic stroke. Cox models were used to relate IGF-1 levels to the risk for incident ischemic stroke, adjusted for potential confounders.Results—During a mean follow-up of 10.2 years, 99 individuals developed ischemic stroke. After adjustment for age, sex, and potentia...
Source: Stroke - June 26, 2017 Category: Neurology Authors: Hamidreza Saber, Jayandra J. Himali, Alexa S. Beiser, Ashkan Shoamanesh, Aleksandra Pikula, Ronenn Roubenoff, Jose R. Romero, Carlos S. Kase, Ramachandran S. Vasan, Sudha Seshadri Tags: Risk Factors, Ischemic Stroke Original Contributions Source Type: research