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Total 125554 results found since Jan 2013.

Blood Pressure-Lowering Treatment With Candesartan in Patients With Acute Hemorrhagic Stroke Brief Reports
Conclusions— There was no evidence that blood pressure–lowering treatment with candesartan is beneficial during the first week of hemorrhagic stroke. Instead, there were signs that such treatment may be harmful, but this needs to be verified in larger studies. Clinical Trial Registration— URL: http://www.clinicaltrials.gov. Unique identifier: NCT00120003.
Source: Stroke - October 27, 2014 Category: Neurology Authors: Jusufovic, M., Sandset, E. C., Bath, P. M. W., Berge, E., on behalf of the Scandinavian Candesartan Acute Stroke Trial Study Group Tags: Cerebrovascular disease/stroke, Acute Cerebral Hemorrhage, Other Stroke Treatment - Medical Brief Reports Source Type: research

Arterial Tortuosity: An Imaging Biomarker of Childhood Stroke Pathogenesis? Clinical Sciences
Conclusions— In children with dissection and transient cerebral arteriopathy, cerebral arteries demonstrate increased tortuosity. Quantified arterial tortuosity may represent a clinically relevant imaging biomarker of vascular biology in pediatric stroke.
Source: Stroke - April 24, 2016 Category: Neurology Authors: Wei, F., Diedrich, K. T., Fullerton, H. J., deVeber, G., Wintermark, M., Hodge, J., Kirton, A., the Vascular Effects of Infection in Pediatric Stroke (VIPS) Investigators, Dowling, Benedict, Bernard, Fox, Friedman, Lo, Ichord, Tan, Mackay, Hernandez, Hump Tags: Risk Factors, Angiography, Magnetic Resonance Imaging (MRI), Ischemic Stroke, Vascular Disease Clinical Sciences Source Type: research

Family History in Young Patients With Stroke Brief Reports
Conclusions— Although present in about a third of patients, a family history of stroke is not specifically related to stroke pathogenic subtypes in patients with young stroke. Young women with stroke more often report stroke in the maternal lineage. Clinical Trial Registration— URL: http://www.clinicaltrials.gov. Unique identifier: NCT00414583.
Source: Stroke - June 22, 2015 Category: Neurology Authors: Thijs, V., Grittner, U., Dichgans, M., Enzinger, C., Fazekas, F., Giese, A.-K., Kessler, C., Kolodny, E., Kropp, P., Martus, P., Norrving, B., Ringelstein, E. B., Rothwell, P. M., Schmidt, R., Tanislav, C., Tatlisumak, T., von Sarnowski, B., Rolfs, A., on Tags: Clinical genetics, Acute Cerebral Infarction, Embolic stroke, Genetics of Stroke Brief Reports Source Type: research

Family History and Risk of Recurrent Stroke Clinical Sciences
Conclusions— This study suggests that elevated risks of recurrent stroke are associated with having relatives with early-onset stroke and siblings with stroke histories, implying that additional precautions may be needed in such populations.
Source: Stroke - July 24, 2016 Category: Neurology Authors: Chung, J.-W., Kim, B. J., Han, M.-K., Kang, K., Park, J.-M., Park, S.-S., Park, T. H., Cho, Y.-J., Hong, K.-S., Lee, K. B., Kim, J. G., Ko, Y., Lee, S., Nah, H.-W., Kim, D.-H., Cha, J.-K., Oh, M.-S., Yu, K.-H., Lee, B.-C., Jang, M. S., Lee, J. S., Lee, J. Tags: Genetics, Quality and Outcomes, Cerebrovascular Disease/Stroke Clinical Sciences Source Type: research

Increased work and social engagement is associated with increased stroke specific quality of life in stroke survivors at 3  months and 12 months post-stroke: a longitudinal study of an Australian stroke cohort.
CONCLUSION: Engaging in work and social activities is an important factor associated with stroke-specific domains of QOL over time. It is recommended that services focus on improving work and social engagement given their importance related to QOL in the first year of recovery post-stroke. Identifying and treating those with depressive symptoms may enhance QOL in the early months post-stroke. TRIAL REGISTRATION: START-PrePARE Australian New Zealand Clinical Trials, www.anzctr.org.au , Registry number: ACTRN12610000987066. EXTEND ClinicalTrial.gov identifier: NCT00887328. PMID: 28438076 [PubMed - as supplied by publisher]
Source: Topics in Stroke Rehabilitation - April 24, 2017 Category: Neurology Authors: Tse T, Binte Yusoff SZ, Churilov L, Ma H, Davis S, Donnan GA, Carey LM, and the START research team Tags: Top Stroke Rehabil Source Type: research

Factors Influencing the Decline in Stroke Mortality: A Statement From the American Heart Association/American Stroke Association AHA/ASA Scientific Statement
Conclusions— The decline in stroke mortality is real and represents a major public health and clinical medicine success story. The repositioning of stroke from third to fourth leading cause of death is the result of true mortality decline and not an increase in mortality from chronic lung disease, which is now the third leading cause of death in the United States. There is strong evidence that the decline can be attributed to a combination of interventions and programs based on scientific findings and implemented with the purpose of reducing stroke risks, the most likely being improved control of hypertension. Thus, ...
Source: Stroke - December 23, 2013 Category: Neurology Authors: Lackland, D. T., Roccella, E. J., Deutsch, A. F., Fornage, M., George, M. G., Howard, G., Kissela, B. M., Kittner, S. J., Lichtman, J. H., Lisabeth, L. D., Schwamm, L. H., Smith, E. E., Towfighi, A., on behalf of the American Heart Association Stroke Coun Tags: AHA Statements and Guidelines AHA/ASA Scientific Statement Source Type: research

In-Hospital Stroke Recurrence and Stroke After Transient Ischemic Attack: Frequency and Risk Factors Clinical Sciences
Conclusions— In-hospital stroke recurrence was low with optimal current management. Patients with a history of TIA, severe symptomatic carotid stenosis, or uncommon causes of stroke were at higher risk. Pneumonia was associated with a higher risk of stroke recurrence in patients with initial TIA or minor stroke but not in the overall population studied. Aphasia may bias the detection rate by concealing new neurological symptoms.
Source: Stroke - March 23, 2015 Category: Neurology Authors: Erdur, H., Scheitz, J. F., Ebinger, M., Rocco, A., Grittner, U., Meisel, A., Rothwell, P. M., Endres, M., Nolte, C. H. Tags: Acute Cerebral Infarction, Carotid Stenosis, Emergency treatment of Stroke, Antiplatelets Clinical Sciences Source Type: research

Rates and Determinants of 5-Year Outcomes After Atrial Fibrillation-Related Stroke: A Population Study Clinical Sciences
Conclusions— AF-stroke is associated with considerable long-term morbidity, fatality, stroke recurrence, and nursing home requirement. Adequately resourced national AF strategies to improve AF detection and prevention are needed.
Source: Stroke - November 23, 2015 Category: Neurology Authors: Hayden, D. T., Hannon, N., Callaly, E., Ni Chroinin, D., Horgan, G., Kyne, L., Duggan, J., Dolan, E., O'Rourke, K., Williams, D., Murphy, S., Kelly, P. J. Tags: Cerebrovascular Disease/Stroke Clinical Sciences Source Type: research

Diagnostic and prognostic role of resistin and copeptin in acute ischemic stroke.
DISCUSSION: Resistin, but not copeptin levels are higher in acute ischemic stroke patients early after the stroke onset, than in age and gender matched stroke-free controls. Moreover, higher copeptin concentrations are predictive of poor short term functional outcome after ischemic stroke. If confirmed in larger prospective studies, resistin and copeptin could improve clinical diagnosis of stroke and effective management of patient recovery. PMID: 28845746 [PubMed - as supplied by publisher]
Source: Topics in Stroke Rehabilitation - August 28, 2017 Category: Neurology Authors: Perovic E, Mrdjen A, Harapin M, Tesija Kuna A, Simundic AM Tags: Top Stroke Rehabil Source Type: research

Does caregiver well-being predict stroke survivor depressive symptoms? A mediation analysis.
Conclusions: Findings indicate that stroke survivor impairments and problems may affect family caregivers and stroke survivors and a high level of caregiver distress may result in poorer outcomes for stroke survivors. Results highlight the likely importance of intervening with both stroke survivors and family caregivers to optimize recovery after stroke. PMID: 23340070 [PubMed - in process]
Source: Topics in Stroke Rehabilitation - January 1, 2013 Category: Neurology Authors: Grant JS, Clay OJ, Keltner NL, Haley WE, Wadley VG, Perkins MM, Roth DL Tags: Top Stroke Rehabil Source Type: research

Psychosocial Distress and Stroke Risk in Older Adults Original Contributions
Conclusions— Increasing levels of psychosocial distress are related to excess risk of both fatal and nonfatal stroke in older black and white adults. Additional research is needed to examine pathways linking psychosocial distress to cerebrovascular disease risk.
Source: Stroke - January 18, 2013 Category: Neurology Authors: Henderson, K. M., Clark, C. J., Lewis, T. T., Aggarwal, N. T., Beck, T., Guo, H., Lunos, S., Brearley, A., Mendes de Leon, C. F., Evans, D. A., Everson-Rose, S. A. Tags: Behavioral/psychosocial - stroke, Risk Factors for Stroke Original Contributions Source Type: research

17q25 Locus Is Associated With White Matter Hyperintensity Volume in Ischemic Stroke, But Not With Lacunar Stroke Status Clinical Sciences
Conclusions— This study provides support for an association between the 17q25 locus and WMH. In contrast, it is not associated with lacunar stroke, suggesting that the association does not act by promoting small-vessel arteriopathy or the same arteriopathy responsible for lacunar infarction.
Source: Stroke - May 24, 2013 Category: Neurology Authors: Adib-Samii, P., Rost, N., Traylor, M., Devan, W., Biffi, A., Lanfranconi, S., Fitzpatrick, K., Bevan, S., Kanakis, A., Valant, V., Gschwendtner, A., Malik, R., Richie, A., Gamble, D., Segal, H., Parati, E. A., Ciusani, E., Holliday, E. G., Maguire, J., Wa Tags: Genetics of Stroke, Computerized tomography and Magnetic Resonance Imaging Clinical Sciences Source Type: research

Impact of Completeness of Ascertainment of Minor Stroke on Stroke Incidence: Implications for Ideal Study Methods Clinical Sciences
Conclusions— Reliance on routine clinical coding underestimates the incidence of minor stroke. To improve comparability of incidence studies, researchers should assess patients referred with transient ischemic attack, and all studies should stratify incidence rates by stroke severity.
Source: Stroke - June 24, 2013 Category: Neurology Authors: Bejot, Y., Mehta, Z., Giroud, M., Rothwell, P. M. Tags: Cerebrovascular disease/stroke, Epidemiology Clinical Sciences Source Type: research

Onset Headache Predicts Good Outcome in Patients With First-Ever Ischemic Stroke Clinical Sciences
Conclusions— By adopting standard classification criteria, this large-scale study demonstrated that onset headache was associated with modest but significantly better outcomes after ischemic stroke.
Source: Stroke - June 24, 2013 Category: Neurology Authors: Chen, P.-K., Chiu, P.-Y., Tsai, I.-J., Tseng, H.-P., Chen, J.-R., Yeh, S.-J., Yeh, S.-J., Sheu, J.-J., Chung, C.-P., Wu, M.-H., Hu, C.-J., Chang, C.-Y., Wei, C.-Y., Yip, P.-K., Sung, S.-F., Wang, S.-J., Hsu, C. Y., the Taiwan Stroke Registry Investigators Tags: Acute Cerebral Infarction Clinical Sciences Source Type: research

Framingham Stroke Risk Score and Cognitive Impairment for Predicting First-Time Stroke in the Oldest Old Clinical Sciences
Conclusions— In the oldest old, the Framingham stroke risk score is not predictive for first-time stroke. In contrast, cognitive impairment, as assessed by MMSE score, identifies subjects at higher risk for stroke.
Source: Stroke - June 24, 2013 Category: Neurology Authors: Sabayan, B., Gussekloo, J., de Ruijter, W., Westendorp, R. G. J., de Craen, A. J. M. Tags: Behavioral/psychosocial - stroke, Cerebrovascular disease/stroke, Pathophysiology, Risk Factors, Behavioral Changes and Stroke Clinical Sciences Source Type: research