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Total 45 results found since Jan 2013.

Combining Human Umbilical Cord Blood Cells With Erythropoietin Enhances Angiogenesis/Neurogenesis and Behavioral Recovery After Stroke
In conclusion, our results suggest that hUCBC infusion in combination with EPO administration demonstrates therapeutic efficacy in the treatment of stroke-induced injury by promoting neurogenesis and angiogenesis. Further research that delineates the therapeutic mechanism of systemically administered hUCBC and EPO is required. Ethics Statement All experimental procedures involving animals were performed in accordance with the Guide for the Care and Use of Laboratory Animals as adopted and promulgated by the U. S. National Institutes of Health and were approved by CHA University Institutional Animal Care & Use Com...
Source: Frontiers in Neurology - April 9, 2019 Category: Neurology Source Type: research

Stroke and syphilis: A retrospective study of 53 patients.
CONCLUSION: A diagnosis of syphilitic stroke should be suspected in young patients as a manifestation of syphilis, and tests for neurosyphilis should be routine in neurology departments to make a prompt diagnosis, thereby preventing psychological sequelae. PMID: 29631855 [PubMed - as supplied by publisher]
Source: Revue Neurologique - April 12, 2018 Category: Neurology Tags: Rev Neurol (Paris) Source Type: research

Young male with syphilitic cerebral arteritis presents with signs of acute progressive stroke: A case report
Conclusion Progressive stroke was the initial symptom of the neurosyphilis. Disease progression is rapid and difficult to control with a single course of penicillin.
Source: Medicine - November 1, 2019 Category: Internal Medicine Tags: Research Article: Clinical Case Report Source Type: research

Cor Triatriatum and Stroke: A Case Report and Review of Literature (P3.294)
Conclusions:This is the largest review of CTS cases with associated stroke. The review showed neuroimaging results consistent with a cardioembolic mechanism. All but two of the cases made use of anticoagulation. Three cases underwent surgery. This case has the longest follow-up and the first to demonstrate failure of anti-platelet therapy and anticoagulation. The need for further investigations regarding optimal stroke prevention in this subset of patients is emphasized.Disclosure: Dr. Diestro has nothing to disclose. Dr. Espiritu has nothing to disclose. Dr. Dorotan has nothing to disclose. Dr. Regalado has nothing to dis...
Source: Neurology - April 17, 2017 Category: Neurology Authors: Diestro, J. D., Espiritu, A., Dorotan, M. K., Regalado, J., Pascual, J. L. Tags: Cerebrovascular Disease Case Reports II Source Type: research

Meningovascular Neurosyphilis Presenting as Ischemic Stroke in an HIV Positive Patient (P2.297)
CONCLUSIONS: MVNS should be considered in AIS patients without known risk factors, especially in patients who are HIV positive. Prompt treatment can halt progression of and possibly improve symptomatology. Diagnosis and improvement can be monitored with intracranial arterial wall imaging using contrast-enhanced MRI.Disclosure: Dr. Tipirneni has nothing to disclose. Dr. Gordon-Perue has nothing to disclose. Dr. DeSousa has nothing to disclose. Dr. Koch has nothing to disclose. Dr. Romano has received personal compensation for activities with NovaVision. Dr. Malik has nothing to disclose.
Source: Neurology - April 8, 2015 Category: Neurology Authors: Tipirneni, A., Gordon-Perue, G., DeSousa, K., Koch, S., Romano, J., Malik, A. Tags: Cerebrovascular Disease and Interventional Neurology: Inflammation and Immunology Source Type: research

Lactobacillus Endocarditis Complicated by Presumed Vertebral Osteomyelitis and Embolic Stroke
In this report, we describe a case in which a 47-year old man with no past medical history develops native aortic valve endocarditis complicated by embolic stroke and presumed lumbar vertebral osteomyelitis.
Source: Infectious Diseases in Clinical Practice - November 1, 2021 Category: Infectious Diseases Tags: Case Reports Source Type: research

How To Avoid China ’ s Medicine Monopoly
I want to share a shocking statistic with you… Around 80% of all the pharmaceuticals sold in America — both prescription and over-the-counter — are manufactured in China. I’m talking about drugs for Parkinson’s and Alzheimer’s, blood pressure and blood thinners, diuretics, aspirin, antibiotics, and a big chunk of the world’s insulin and diabetes drugs — just to name a few.1 We don’t even make penicillin anymore. The last penicillin plant in the U.S. closed its doors in 2004. Americans who rely on medicine are now almost entirely at the mercy of a country whose relations with the U.S. have become more ...
Source: Al Sears, MD Natural Remedies - September 19, 2023 Category: Complementary Medicine Authors: Jacob Tags: Health Source Type: news

One night with venus, a lifetime with mars
I present a case of neurosyphilis presenting as acute stroke in a 44-year-old male; I review the current literature, with a particular emphasis on diagnostics and the pitfalls of serological testing. Neurosyphilis is an imprecise term and subsumes meningitic, meningovascular, parenchymatous and gummatous syphilis. Of these, meningovascular syphilis is most commonly associated with large vessel arteritis and stroke, particularly of the middle cerebral artery. Although syphilis rates have increased since the latter part of the 20th century, neurosyphilis remains a rare disease and epidemiological estimates are marred by impr...
Source: Journal of Neurology, Neurosurgery and Psychiatry - September 9, 2014 Category: Neurosurgery Authors: Johnson, J. Tags: Abstracts Source Type: research

Canagliflozin Inhibits Human Endothelial Cell Proliferation and Tube Formation
In conclusion, the present study identified canagliflozin as a potent inhibitor of human EC proliferation. The anti-proliferative action of canagliflozin is observed in ECs isolated from both the venous and arterial circulation, and is partly due to the blockade of cyclin A expression. In addition, this study found that canagliflozin inhibits tube formation in cultured ECs and mouse aortic rings. Notably, these actions are specific for canagliflozin and not seen with other SGLT2 inhibitors. The ability of canagliflozin to exert these pleiotropic effects on EC function may contribute to both the adverse and salutary actions...
Source: Frontiers in Pharmacology - April 15, 2019 Category: Drugs & Pharmacology Source Type: research

Comprehensive integrated care for patients with sickle cell disease in a remote aboriginal tribal population in southern India
ConclusionHigh quality comprehensive care for SCD can be delivered for a low income, aboriginal population in India through a community driven network of care. This model can serve as a template for healthcare delivery for SCD in low‐income communities. Pediatr Blood Cancer © 2013 Wiley Periodicals, Inc.
Source: Pediatric Blood and Cancer - December 18, 2013 Category: Cancer & Oncology Authors: Vivek Nimgaonkar, Lakshmanan Krishnamurti, Hari Prabhakar, Nandakumar Menon Tags: Research Article Source Type: research

Have antibiotic changes upped heart infections?
Conclusion This is valuable and timely research, which has looked at trends before and after NICE's 2008 guidance on the prevention of infective endocarditis in people undergoing invasive procedures. This examined: changes in the prescription of antibiotics for the prevention of infective endocarditis changes in the number of cases of infective endocarditis diagnosed NICE's recommendation was based on an examination of the evidence of the effectiveness of antibiotics in preventing infective endocarditis, weighing the benefits and health outcomes (such as reduction in illness and deaths), risks and costs.   The ...
Source: NHS News Feed - November 19, 2014 Category: Consumer Health News Tags: Heart/lungs Medical practice Source Type: news

Acute rheumatic Fever and rheumatic heart disease among children - american samoa, 2011-2012.
Abstract Acute rheumatic fever is a nonsuppurative, immune-mediated consequence of group A streptococcal pharyngitis (strep throat). Recurrent or severe acute rheumatic fever can cause permanent cardiac valve damage and rheumatic heart disease, which increases the risk for cardiac conditions (e.g., infective endocarditis, stroke, and congestive heart failure). Antibiotics can prevent acute rheumatic fever if administered no more than 9 days after symptom onset. Long-term benzathine penicillin G (BPG) injections are effective in preventing recurrent acute rheumatic fever attacks and are recommended to be administer...
Source: MMWR Morb Mortal Wkl... - May 29, 2015 Category: Epidemiology Authors: Beaudoin A, Edison L, Introcaso CE, Goh L, Marrone J, Mejia A, Beneden CV Tags: MMWR Morb Mortal Wkly Rep Source Type: research

Management of Sickle Cell Disease: Recommendations from the 2014 Expert Panel Report.
Abstract Family physicians are the primary and sometimes only health care resource for families affected by sickle cell disease. Recently published guidelines provide important recommendations for health maintenance, acute care, and monitoring of disease-modifying therapy in persons with this condition. This overview highlights some of the most important clinical activities that can and should be carried out in the community care setting. Children with sickle cell anemia should receive prophylactic penicillin from birth through at least five years of age, and all persons with sickle cell disease require vaccinatio...
Source: American Family Physician - December 15, 2015 Category: Primary Care Authors: Yawn BP, John-Sowah J Tags: Am Fam Physician Source Type: research

Seven key actions to eradicate rheumatic heart disease in Africa: the Addis Ababa communiqué.
nedy N, Lwabi P, Mamo Y, Mntla P, Sutton C, Mocumbi AO, Mondo C, Mtaja A, Musuku J, Mucumbitsi J, Murango L, Nel G, Ogendo S, Ogola E, Ojji D, Olunuga TO, Redi MM, Rusingiza KE, Sani M, Sheta S, Shongwe S, van Dam J, Gamra H, Carapetis J, Lennon D, Mayosi BM Abstract Acute rheumatic fever (ARF) and rheumatic heart disease (RHD) remain major causes of heart failure, stroke and death among African women and children, despite being preventable and imminently treatable. From 21 to 22 February 2015, the Social Cluster of the Africa Union Commission (AUC) hosted a consultation with RHD experts convened by the Pan-Africa...
Source: Cardiovascular Journal of Africa - January 12, 2016 Category: Cardiology Authors: Watkins D, Zuhlke L, Engel M, Daniels R, Francis V, Shaboodien G, Kango M, Abul-Fadl A, Adeoye A, Ali S, Al-Kebsi M, Bode-Thomas F, Bukhman G, Damasceno A, Goshu DY, Elghamrawy A, Gitura B, Haileamlak A, Hailu A, Hugo-Hamman C, Justus S, Karthikeyan G, Ke Tags: Cardiovasc J Afr Source Type: research

Complications of sickle cell anaemia in children in Northwestern Tanzania.
Conclusion Children with SCA receiving care in Tanzania are diagnosed late, hospitalized frequently, and have severe complications. Opportunities exist to improve care through wider access to screening and diagnosis as well as better coordination of comprehensive care. PMID: 26868490 [PubMed - as supplied by publisher]
Source: Hematology - February 14, 2016 Category: Hematology Tags: Hematology Source Type: research