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Anxiety in Patients With Acute Ischemic Stroke: Risk Factors and Effects on Functional Status
Conclusion: Depressive symptoms are the major correlates of PSA while more severe PSA is associated with poorer ADL and health-related QOL. Acute lesions involving CHWM may correlate with PSA in ischemic stroke patients with mild-to-moderate neurologic deficits, supporting a lesion-location hypothesis in PSA.IntroductionAnxiety is prevalent after stroke and occurs in about one-quarter of stroke survivors (1, 2). Poststroke anxiety (PSA) may have a negative impact on quality of life (QOL) of stroke survivors, affecting their rehabilitation (3). Furthermore, one prospective study found that severe anxiety symptoms were assoc...
Source: Frontiers in Psychiatry - April 16, 2019 Category: Psychiatry Source Type: research

Stroke impairment categories: A new way to classify the effects of stroke based on stroke-related impairments.
CONCLUSIONS: A classification system of seven Stroke Impairment Categories has been presented. PMID: 33131321 [PubMed - as supplied by publisher]
Source: Clinical Rehabilitation - November 1, 2020 Category: Rehabilitation Authors: Gittins M, Lugo-Palacios D, Vail A, Bowen A, Paley L, Bray B, Tyson S Tags: Clin Rehabil Source Type: research

Rehabilitation using virtual gaming for Hospital and hOMe-Based training for the Upper limb post Stroke (RHOMBUS II): protocol of a feasibility randomised controlled trial
Introduction Upper limb (UL) rehabilitation is most effective early after stroke, with higher doses leading to improved outcomes. For the stroke survivor, the repetition may be monotonous. For clinicians, providing a clinically meaningful level of input can be challenging. As such, time spent engaged in UL activity among subacute stroke survivors remains inadequate. Opportunities for the stroke survivor to engage with UL rehabilitation in a safe, accessible and engaging way are essential to improving UL outcomes following stroke. The NeuroBall is a non-immersive virtual reality (VR) digital system designed for stroke rehab...
Source: BMJ Open - June 7, 2022 Category: General Medicine Authors: Kilbride, C., Warland, A., Stewart, V., Aweid, B., Samiyappan, A., Ryan, J., Butcher, T., Athanasiou, D. A., Baker, K., Singla-Buxarrais, G., Anokye, N., Pound, C., Gowing, F., Norris, M. Tags: Open access, Rehabilitation medicine Source Type: research

130 Improving the implementation of anti-coagulation therapy in AF patients at risk of stroke in a primary care setting
Background: Atrial fibrillation (AF) is the most common sustained arrhythmia of the heart and is of increasing prevalence1. There are strong implications of increased stroke risk in AF patients2. In particular, AF related stroke carries a near 50% risk of persisting disability and directly increases costs for treatment by over a third in comparison with non AF stroke patients3,4. As an estimated contributing cause of 15-20% of all strokes, the economic and societal impact of AF is of extreme importance5. To monitor how efficiently stroke prevention is implemented in a primary care setting we will identify those ‘at riskâ...
Source: Europace - October 5, 2017 Category: Cardiology Source Type: research

Population-based stroke surveillance using big data: state-wide epidemiological trends in admissions and mortality in New South Wales, Australia.
DISCUSSION: Improved prevention may have underpinned declining intracerebral haemorrhage rates while survival gains suggest that innovations in care are being successfully translated. Mortality in patients surviving the acute period is unchanged and may be increasing for subarachnoid haemorrhage warranting investment in post-discharge care and secondary prevention. PMID: 32449879 [PubMed - as supplied by publisher]
Source: Neurological Research - May 26, 2020 Category: Neurology Tags: Neurol Res Source Type: research

Investigating the association between inpatient stroke therapy and disability, destination on discharge, length of stay and mortality: a prospective cohort study using the Sentinel Stroke National Audit Programme
Conclusions Our findings suggest for stroke inpatients requiring therapy, ‘More is better’ may be overly simplistic. Strong limitations associated with analysis of routine data restrict further robust investigation of the therapy–response relationship. Robust prospective work is urgently needed to further investigate the relationships observed here.
Source: BMJ Open - April 1, 2022 Category: General Medicine Authors: Gittins, M., Lugo-Palacios, D. G., Vail, A., Bowen, A., Paley, L., Bray, B., Gannon, B., Tyson, S. Tags: Open access, Rehabilitation medicine Source Type: research

IJERPH, Vol. 19, Pages 14587: Returning to Leisure Activity Post-Stroke: Barriers and Facilitators to Engagement
Conclusions: Physical difficulties and lack of energy are problematic for stroke and TIA survivors who want to return to or participate in leisure activity. Healthcare support alone cannot overcome all practical and emotional issues related to leisure activity engagement. Family support and improving well-being are important facilitators and future research should explore these mechanisms further.
Source: International Journal of Environmental Research and Public Health - November 7, 2022 Category: Environmental Health Authors: Joanna Harrison Clare Thetford Matthew J. Reeves Christopher Brown Miland Joshi Caroline Watkins Tags: Article Source Type: research

Stroke patients in Wales ‘could die’ because thrombectomy not available
Acute shortage in NHS of specialist doctors who undertake life-saving treatment means hospitals cannot provide itStroke patients in Wales are being denied a life-saving pioneering treatment after the surgical team providing it had to be mothballed because of an acute NHS shortage of the specialist doctors who undertake the procedure.Internal NHS emails obtained by the Guardian reveal that health service bosses in Wales are pleading with hospitals in England to perform mechanical thrombectomy on their patients to save them from disability and death.Continue reading...
Source: Guardian Unlimited Science - October 1, 2017 Category: Science Authors: Denis Campbell Health policy editor Tags: Stroke NHS Wales Health Medical research Society Doctors Science UK news Source Type: news

Glutamate Transport and Preterm Brain Injury
Silvia Pregnolato1*, Elavazhagan Chakkarapani1, Anthony R. Isles2 and Karen Luyt1 1Department of Neonatal Neurology, Translational Health Sciences, Bristol Medical School, University of Bristol, Bristol, United Kingdom 2Behavioural Genetics Group, MRC Centre for Neuropsychiatric Genetics and Genomics, School of Medicine, Cardiff University, Cardiff, United Kingdom Preterm birth complications are the leading cause of child death worldwide and a top global health priority. Among the survivors, the risk of life-long disabilities is high, including cerebral palsy and impairment of movement, cognition, and beh...
Source: Frontiers in Physiology - April 23, 2019 Category: Physiology Source Type: research

Age-Dependence of Flow Homeostasis in the Left Ventricle
Conclusions: In average, blood spends 1 to 3 beats inside the LV with very low shear stress rates. The apical region is the most prone to blood stasis, particularly in mid-aged adults. The washout of blood in the normal LV is age-dependent due to physiological changes in the degree of apical penetration of the filling waves. Introduction Cardioembolic stroke is a major source of mortality and disability worldwide and blood stasis one of its major determinants (Adams et al., 1986). Left ventricular (LV) function has evolved to maximize mechanical efficiency and ensure organ perfusion at a low cost of energy and fill...
Source: Frontiers in Physiology - April 25, 2019 Category: Physiology Source Type: research

Nanomaterials Versus Ambient Ultrafine Particles: An Opportunity to Exchange Toxicology Knowledge
Conclusion: There is now an opportunity to apply knowledge from NM toxicology and use it to better inform PM health risk research and vice versa. https://doi.org/10.1289/EHP424 Received: 17 December 2015 Revised: 12 August 2016 Accepted: 30 August 2016 Published: 10 October 2017 Address correspondence to V. Stone, School of Life Sciences, Heriot-Watt University, Edinburgh, UK. Telephone: +44 131 451 3460. Email: v.stone@hw.ac.uk V.S. currently receives grant funding from Byk Altana and from The European Ceramic Fibre Industry Association (ECFIA). In the past, V.S. has received funding from Unilever and GlaxoSmithKline....
Source: EHP Research - October 10, 2017 Category: Environmental Health Authors: Daniil Lyalko Tags: Review Source Type: research

Associations between Ambient Fine Particulate Oxidative Potential and Cardiorespiratory Emergency Department Visits
Conclusions: Lag 0–2 OPDTT was associated with ED visits for multiple cardiorespiratory outcomes, providing support for the utility of OPDTT as a measure of fine particle toxicity. https://doi.org/10.1289/EHP1545 Received: 23 December 2016 Revised: 4 August 2017 Accepted: 12 August 2017 Published: 26 October 2017 Please address correspondence to J.Y. Abrams, Centers for Disease Control and Prevention, NCEZID/DHCPP, 1600 Clifton Rd. NE, CDC Mailstop A30, Atlanta, GA 30333 USA. Telephone: (404) 639-5121. Email: jabrams@cdc.gov Supplemental Material is available online (https://doi.org/10.1289/EHP1545). The authors ...
Source: EHP Research - October 26, 2017 Category: Environmental Health Authors: Daniil Lyalko Tags: Research Source Type: research

Evaluation of the MCAST, a multidisciplinary toolkit to improve mental capacity assessment.
Conclusions: The MCAST is the first toolkit to support the needs of individuals with communication disabilities during mental capacity assessments. It enables assessors to deliver high quality, legally compliant and confident practice.IMPLICATIONS FOR REHABILITATIONMental capacity assessment practice needs to be improved to maximise patient autonomy, safety and well-being.The MCAST is a paper-based toolkit designed to facilitate and improve mental capacity practice in England and Wales.This study suggests the MCAST would be easy and acceptable to use in healthcare settings and could lead to improvements in assessment quali...
Source: Disability and Rehabilitation - May 22, 2020 Category: Rehabilitation Authors: Jayes M, Palmer R, Enderby P Tags: Disabil Rehabil Source Type: research

How are adults with capacity-affecting conditions and associated communication difficulties included in ethically sound research? A documentary-based survey of ethical review and recruitment processes under the research provisions of the Mental Capacity Act (2005) for England and Wales
Conclusions People with capacity-affecting conditions and associated communication difficulties continue to be excluded from research, with recruitment efforts largely concentrated around participant-facing documentation. There is a need for a more nuanced approach if such individuals are to be included in ethically sound research.
Source: BMJ Open - March 31, 2022 Category: General Medicine Authors: Bunning, K., Jimoh, O. F., Heywood, R., Killett, A., Ryan, H., Shiggins, C., Langdon, P. E. Tags: Open access, Ethics Source Type: research