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Condition: Allergy
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Total 381 results found since Jan 2013.
Acute camptocormia as the presenting symptom of tetanus
We report an unusual case of tetanus with camptocormia as the initial symptom. Case presentation A 77-year-old female farmer with unremarkable medical history arrived at our hospital due to difficulty in swallowing and a dropped head which were noticed 4 days prior to the visit. On examination at arrival, she had camptocormia with increased tonus of rectus abdominis muscle. She also had hoarseness in speech and mild limitation in opening her mouth. No wound was observed. Investigation On laryngoscopy, saliva was pooling around the epiglottis with decreased mobility. Therefore, she was admitted to the intensive care un...
Source: Journal of Neurology, Neurosurgery and Psychiatry - July 9, 2014 Category: Neurosurgery Authors: Kaji, S., Shibayama, H., Sato, S., Fukutake, T. Tags: Immunology (including allergy), Muscle disease, Neuromuscular disease, Pain (neurology), Stroke, Ophthalmology, Radiology, Drugs: musculoskeletal and joint diseases, Musculoskeletal syndromes, Surgical diagnostic tests, Radiology (diagnostics), Ear, nose Source Type: research
Lung cancer screening with low-dose CT (LDCT) is ready for prime time in the USA
Commentary on: Humphrey LL, Deffebach M, Pappas M, et al.. Screening for lung cancer with low-dose computed tomography: a systematic review to update the US Preventive Services Task Force recommendation. Ann Intern Med 2013;159:411–20. Context The US Preventative Services Task Force (USPSTF) has published their long-awaited, updated systematic review of low-dose CT (LDCT) screening for lung cancer. Last reviewed in 2004, lung cancer screening has been under intense study worldwide for the past decade. The issue of lung cancer screening is important because lung cancer is the leading cause of cancer mortality in the U...
Source: Evidence-Based Medicine - July 18, 2014 Category: Internal Medicine Authors: Wilson, D. O. Tags: Smoking and tobacco, Health policy, Clinical trials (epidemiology), Epidemiologic studies, Immunology (including allergy), Stroke, Screening (oncology), Radiology, Clinical diagnostic tests, Radiology (diagnostics), Screening (epidemiology), Health econom Source Type: research
Adverse outcomes after major surgery in patients with systemic lupus erythematosus: a nationwide population-based study
Conclusions
SLE significantly increased the risks of surgical patients for overall major complications and mortality after major surgery. Our findings demonstrated the need for integrated care and revised protocols for perioperative management to improve outcomes for surgical patients with SLE.
Source: Annals of the Rheumatic Diseases - July 31, 2014 Category: Rheumatology Authors: Lin, J.-A., Liao, C.-C., Lee, Y.-J., Wu, C.-H., Huang, W.-Q., Chen, T.-L. Tags: Immunology (including allergy), Connective tissue disease, Systemic lupus erythematosus, Epidemiology Clinical and epidemiological research Source Type: research
Prevalence and risk factors of dry eye disease in a British female cohort.
CONCLUSIONS: DED is common and increases with age within this cohort of female twins. We confirmed established risk factors for the first time in a British population, and found important risk factors that might relate to an underlying aetiology involving chronic pain predisposition or somatisation.
PMID: 25185440 [PubMed - as supplied by publisher]
Source: The British Journal of Ophthalmology - September 3, 2014 Category: Opthalmology Authors: Vehof J, Kozareva D, Hysi PG, Hammond CJ Tags: Br J Ophthalmol Source Type: research
Association between indices of clinically‐defined periodontitis and self‐reported history of systemic medical conditions
ConclusionsThe findings confirm the results from previous investigations in which a number of systemic medical conditions were significantly associated with probing pocket depth and/or CAL.
Source: Journal of Investigative and Clinical Dentistry - July 22, 2014 Category: Dentistry Authors: Nikolaos A. Chrysanthakopoulos, Panagiotis A. Chrysanthakopoulos Tags: Original Article Source Type: research
When less is more: primary immunodeficiency with an autoinflammatory kick
Purpose of reviewNext-generation sequencing is revolutionizing the molecular taxonomy of human disease. Recent studies of patients with unexplained autoinflammatory disorders reveal germline genetic mutations that target important regulators of innate immunity.
Recent findingsWhole-exome analyses of previously undiagnosed patients have catalyzed the recognition of two new disease genes. First, a phenotypic spectrum, including livedo racemosa, fever with early-onset stroke, polyarteritis nodosa, and Sneddon syndrome, is caused by loss-of-function mutations in cat eye syndrome chromosome region, candidate 1 (CECR1), encoding...
Source: Current Opinion in Allergy and Clinical Immunology - October 24, 2014 Category: Allergy & Immunology Tags: PRIMARY IMMUNE DEFICIENCY DISEASE: Edited by Ramsay L. Fuleihan and Bruce D. Mazer Source Type: research
NIH-led study explores prevention of heart disease in HIV-infected people
(NIH/National Institute of Allergy and Infectious Diseases) The National Institutes of Health has launched a clinical trial to assess the effects of aspirin and cholesterol-lowering drugs, or statins, on preventing cardiovascular disease in people with long-term HIV infections. This group, which includes people on antiretroviral therapy as well as 'elite controllers' who can limit the virus without antiretroviral therapy, have a higher risk of developing heart disease and stroke compared to the general population.
Source: EurekAlert! - Medicine and Health - October 28, 2014 Category: Global & Universal Source Type: news
Prevalence and risk factors of dry eye disease in a British female cohort
Conclusions
DED is common and increases with age within this cohort of female twins. We confirmed established risk factors for the first time in a British population, and found important risk factors that might relate to an underlying aetiology involving chronic pain predisposition or somatisation.
Source: British Journal of Ophthalmology - November 14, 2014 Category: Opthalmology Authors: Vehof, J., Kozareva, D., Hysi, P. G., Hammond, C. J. Tags: Lens and zonules, Press releases, Neurology Original articles - Clinical science Source Type: research
The link between hyperoxia, delayed cerebral ischaemia and poor outcome after aneurysmal SAH: association or therapeutic endeavour
In this study, Jeon et al1 assess the association between exposure to hyperoxia in ventilated patients following aneurysmal subarachnoid haemorrhage (SAH) and both delayed cerebral ischaemia (DCI) and functional outcome. Prospective data from an observational cohort of patients with available partial pressure of oxygen (PaO2) was retrospectively assessed. Hyperoxia was defined as the highest quartile of PaO2 (≥173 mm Hg) and poor outcome as modified Rankin scale 4–6 three months after SAH. Of 252 included patients, there were no significant differences in baseline characteristics between patients with an...
Source: Journal of Neurology, Neurosurgery and Psychiatry - November 17, 2014 Category: Neurosurgery Authors: Starke, R. M., Kassell, N. F. Tags: Immunology (including allergy), Neurological injury, Stroke, Trauma CNS / PNS, Trauma, Injury Editorial commentaries Source Type: research
Study concludes L. reuteri not effective for infant colic, but findings may be limited by participants' heterogeneity
Commentary on: Sung V, Hiscock H, Tang ML, et al.. Treating infant colic with the probiotic Lactobacillus reuteri: double blind, placebo controlled randomised trial. BMJ 2014;348:g2107. Context Colic is a common problem in healthy, thriving infants that is associated with excessive crying over a regular period during the day and is sustained for the first few months of life.1 Colic affects between 5% and 19% of young infants, remains difficult to treat and may result in significant psychosocial consequences. Despite 40 years of research, the aetiology of infantile colic remains elusive. Recently, the composition of in...
Source: Evidence-Based Medicine - November 19, 2014 Category: Internal Medicine Authors: Indrio, F. Tags: Clinical trials (epidemiology), Immunology (including allergy), Pain (neurology), Stroke, Childhood nutrition, Pregnancy, Child and adolescent psychiatry, Mood disorders (including depression) Therapeutics Source Type: research
ACE inhibitors are associated with a reduction in all-cause mortality versus angiotensin II receptor blockers in patients with diabetes mellitus
Commentary on: Cheng J, Zhang W, Zhang X, et al.. Effect of angiotensin-converting enzyme inhibitors and angiotensin II receptor blockers on all-cause mortality, cardiovascular deaths, and cardiovascular events in patients with diabetes mellitus: a meta-analysis. JAMA Intern Med 2014;174:773–85. Context Renin-angiotensin system blockade has been proven to reduce mortality and morbidity in populations at high risk for cardiovascular events. This extends to the patients with diabetes mellitus, where evidence-based guidelines recommend first -line treatment with ACE inhibitors (ACEIs) or angiotensin II receptor blockers...
Source: Evidence-Based Medicine - November 19, 2014 Category: Internal Medicine Authors: Harel, Z., Silver, S. A. Tags: Epidemiologic studies, Immunology (including allergy), Drugs: cardiovascular system, Drugs: CNS (not psychiatric), Stroke, Hypertension, Ischaemic heart disease, Diabetes, Guidelines Therapeutics Source Type: research
A fine neuroscience vintage
I recently bumped into a cardiologist mate who had just won a silver medal for his first wild barrel ferment Chardonnay from the vineyard he started with a haematologist, their wine label aptly named Blood Brothers. He told me his approach to cultivating a fine harvest. While many factors play a role he said, the raw product and how it is nurtured, remains the key. The grape variety and how it responds to the prevailing climate at the time of harvest are the critical factors in producing a fine wine vintage. After our conversation, I was impelled to draw a parallel between his wine making and the process of extracting prac...
Source: Journal of Neurology, Neurosurgery and Psychiatry - December 17, 2014 Category: Neurosurgery Authors: Kiernan, M. C. Tags: Genetics, Long term care, Immunology (including allergy), Dementia, Epilepsy and seizures, Motor neurone disease, Movement disorders (other than Parkinsons), Multiple sclerosis, Neuromuscular disease, Peripheral nerve disease, Spinal cord, Stroke, Memory Source Type: research
Metabolic diseases in parents and grandparents predict asthma and hay fever in offspring
Conclusion: This is the first study to show that familial cardio-metabolic disease predicts specific asthma phenotypes and hay fever, independent of familial asthma, suggesting that two distinct pathways carry asthma risk across generations, via familial asthma as well as cardio-metabolic disease.
Source: European Respiratory Journal - December 23, 2014 Category: Respiratory Medicine Authors: Carsin, A.-E., Svanes, C., Sunyer, J., Dratva, J., Norback, D., Holm, M., Lindberg, E., Benediktsdottir, B., Forsberg, B., Jogi, R., Schlunssen, V., Franklin, K., Gislason, T., Sigsgaard, T., Heinrich, J., Janson, C., Dharmage, S., Johannessen, A., Gomez Tags: 10.1 Respiratory Infections Source Type: research
Epinephrine in Anaphylaxis: Higher Risk of Cardiovascular Complications and Overdose After Administration of Intravenous Bolus Epinephrine Compared with Intramuscular Epinephrine
Conclusion The risk of overdose and adverse CV events is significantly higher with IV bolus epinephrine administration. Analysis of the data supports the safety of IM epinephrine and a need for extreme caution and further education about IV bolus epinephrine in anaphylaxis.
Source: The Journal of Allergy and Clinical Immunology: In Practice - January 7, 2015 Category: Allergy & Immunology Source Type: research
Psoriasis, psoriatic arthritis and cardiovascular risk: are we closer to a clinical recommendation?
The issue of vascular risk in chronic arthropathies and especially the magnitude of such risk and its clinical implications in daily practice are of considerable current importance. Similarly, the relative risk across distinct arthropathies and other chronic inflammatory conditions is debated. Ogdie et al1 report associations between psoriasis, psoriatic arthritis (PsA), rheumatoid arthritis (RA) and an increased risk of major adverse cardiovascular events (MACE—myocardial infarction, stroke and cardiovascular death) in data derived from the UK primary care registry. Results are stratified by use of disease-modifying...
Source: Annals of the Rheumatic Diseases - January 7, 2015 Category: Rheumatology Authors: Kristensen, S. L., McInnes, I. B., Sattar, N. Tags: Immunology (including allergy), Inflammation, Biological agents, Connective tissue disease, Degenerative joint disease, Drugs: musculoskeletal and joint diseases, Musculoskeletal syndromes, Rheumatoid arthritis, Epidemiology Editorials Source Type: research
