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Specialty: Research
Condition: Atrial Fibrillation
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Total 257 results found since Jan 2013.
Impact of methodological choices on a meta-analysis of real-world evidence comparing non-vitamin K antagonist oral anticoagulants with vitamin K antagonists for the treatment of patients with non-valvular atrial fibrillation.
Conclusions Sensitivity analyses showed the impact of similar assumptions was different depending on the outcome, and the drug considered. The development of recommendations and guidelines for the inclusion of RWE in meta-analyses could prove useful in evaluating the effectiveness of health care interventions.
PMID: 31328580 [PubMed - as supplied by publisher]
Source: Current Medical Research and Opinion - July 24, 2019 Category: Research Tags: Curr Med Res Opin Source Type: research
Economic evaluation of prolonged and enhanced ECG Holter monitoring in acute ischemic stroke patients.
Conclusions: EPM yielded reduced not significantly different costs without affecting QoL and may be a useful strategy to detect PAF in acute ischemic stroke patients in time.
PMID: 31315471 [PubMed - as supplied by publisher]
Source: Current Medical Research and Opinion - July 19, 2019 Category: Research Tags: Curr Med Res Opin Source Type: research
The Association Between the Use of Antiarrhythmic Drugs in Non-Valvular Atrial Fibrillation and Patient Prognosis Using Data from the China Atrial Fibrillation (China-AF) Registry.
CONCLUSIONS AAD usage was associated with lower risk of 1-year all-cause mortality and cardiovascular death in "real-world" patients with NVAF.
PMID: 31256190 [PubMed - in process]
Source: Medical Science Monitor - July 1, 2019 Category: Research Tags: Med Sci Monit Source Type: research
Worsening renal function, adverse clinical events, and major determinants for changes of renal function in patients with atrial fibrillation: a Japanese multicenter registry substudy.
Conclusion: Age ≥75 years, body weight ≤50 kg, a history of heart failure, and initially preserved renal function appear to promote renal dysfunction in patients with AF, but a history of AF ablation seems to have a favorable effect. Worsening renal function seems to increase AF patients' risk of adverse clinical events. Renal function can decline quickly; thus, early intervention including AF ablation is warranted.
PMID: 31204852 [PubMed - as supplied by publisher]
Source: Current Medical Research and Opinion - June 18, 2019 Category: Research Tags: Curr Med Res Opin Source Type: research
Warfarin therapy in Chinese patients with atrial fibrillation treated with percutaneous coronary intervention: a 5-year follow-up retrospective cohort study.
Conclusions: Warfarin reduces the incidence of MACCEs but does not increase bleeding events in Chinese patients with AF who underwent PCI. For patients taking warfarin, recurrent myocardial infarction and a baseline CHA2DS2-VASc score >4 were related to MACCE occurrence.
PMID: 31144555 [PubMed - as supplied by publisher]
Source: Current Medical Research and Opinion - June 1, 2019 Category: Research Tags: Curr Med Res Opin Source Type: research
Continuation with apixaban treatment is associated with lower risk for hospitalization and medical costs among elderly patients.
Conclusion: Elderly patients with NVAF in the U.S. who continued with apixaban treatment had a lower risk of MB-related hospitalization and lower MB- and stroke/SE-related medical costs compared to patients who switched to another OAC.
PMID: 31120309 [PubMed - as supplied by publisher]
Source: Current Medical Research and Opinion - May 25, 2019 Category: Research Tags: Curr Med Res Opin Source Type: research
Long-Term Persistence with Newly-Initiated Warfarin or Non-VKA Oral Anticoagulant (NOAC) in Patients with Non-Valvular Atrial Fibrillation: Insights from the Prospective China-AF Registry.
CONCLUSIONS Treatment persistence of NOACs was lower than that of warfarin among Chinese patients with AF. Patients with characteristics of non-persistence predictors need special attention to maintain their therapy.
PMID: 30971681 [PubMed - in process]
Source: Medical Science Monitor - April 12, 2019 Category: Research Tags: Med Sci Monit Source Type: research
Effectiveness and safety of rivaroxaban in nonvalvular atrial fibrillation: data from a contemporary Spanish registry.
CONCLUSIONS: In this contemporary Spanish cohort of NVAF patients on rivaroxaban, patients had many comorbidities, a high thromboembolic risk and a moderate bleeding risk. Overall, rates of stroke and bleeding complications were low and similar to other previous studies. These data suggest that rivaroxaban is effective and safe in routine practice.
PMID: 30912682 [PubMed - as supplied by publisher]
Source: Current Medical Research and Opinion - March 27, 2019 Category: Research Tags: Curr Med Res Opin Source Type: research
Safety and Efficacy of Triple Antithrombotic Therapy with Dabigatran versus Vitamin K Antagonist in Atrial Fibrillation Patients: A Pilot Study.
Conclusion: Dabigatran at the dose used for stroke prevention appears safer than VKA and maintains a similar efficacy profile, when used with DAPT, in AF patients who have undergone PCI with stenting for ACS.
PMID: 30895193 [PubMed - in process]
Source: Biomed Res - March 22, 2019 Category: Research Authors: Russo V, Rago A, Proietti R, Attena E, Rainone C, Crisci M, Papa AA, Calabrò P, D'Onofrio A, Golino P, Nigro G Tags: Biomed Res Int Source Type: research
Big data adds clarity, certainty to clinical trial outcomes for AFib
ROCHESTER, Minn. -- The 33 million people with atrial fibrillation worldwide not only suffer from bothersome symptoms, but also face a fivefold increased risk of stroke and a twofold increased risk of death. Research teams led by Mayo Clinic published three connected studies on Friday, March 15, clarifying the benefits of catheter ablation versus rate- [...]
Source: Mayo Clinic Research News - March 14, 2019 Category: Research Source Type: news
Bioinformatic gene analysis for potential biomarkers and therapeutic targets of atrial fibrillation-related stroke
Atrial fibrillation (AF) is one of the most prevalent sustained arrhythmias, however, epidemiological data may understate its actual prevalence. Meanwhile, AF is considered to be a major cause of ischemic stro...
Source: Journal of Translational Medicine - February 13, 2019 Category: Research Authors: Rongjun Zou, Dingwen Zhang, Lei Lv, Wanting Shi, Zijiao Song, Bin Yi, Bingjia Lai, Qian Chen, Songran Yang and Ping Hua Tags: Research Source Type: research
Mandibular Advancement Devices in Patients with Symptoms of Obstructive Sleep Apnea: A Review.
Authors: Wojda M, Jurkowski P, Lewandowska A, Mierzwińska-Nastalska E, Kostrzewa-Janicka J
Abstract
Obstructive sleep apnea (OSA) is a sleep disorder resulting from the repetitive narrowing and collapse of the upper respiratory tract. The results of previous epidemiological studies confirm a significant impact of OSA on the health situation around the world. Untreated OSA is associated with many adverse health effects, such as hypertension, coronary artery disease, stroke, atrial fibrillation, congestive heart failure, and daytime sleepiness. Excessive mortality of OSA patients, especially in men under 50 years o...
Source: Advances in Experimental Medicine and Biology - January 29, 2019 Category: Research Tags: Adv Exp Med Biol Source Type: research
Evaluation of the Influence of Etiological Factors on the Economic Burden of Ischemic Stroke in Younger Patients in China Using the Trial of Org 10172 in Acute Stroke Treatment (TOAST) Classification.
CONCLUSIONS In the younger patient population in China, etiological factors influenced the economic burden of ischemic stroke.
PMID: 30666992 [PubMed - in process]
Source: Medical Science Monitor - January 24, 2019 Category: Research Tags: Med Sci Monit Source Type: research
Predictive Value of A2HD Scoring for Transient Symptoms Associated with Infarction.
CONCLUSIONS Risk of TSI seems to be highly predictable. The A2HD score can be used in clinical practice to identify high-risk cerebral infarction patients with TIA who need emergency diagnosis and treatment.
PMID: 30601800 [PubMed - in process]
Source: Medical Science Monitor - January 4, 2019 Category: Research Tags: Med Sci Monit Source Type: research
FDA-Catalyst-Using FDA's Sentinel Initiative for large-scale pragmatic randomized trials: Approach and lessons learned during the planning phase of the first trial.
CONCLUSION:: Sentinel infrastructure generated preliminary data that supported planning and implementation of a large pragmatic trial embedded in health plans. This planning identified unanticipated challenges that must be addressed in similar trials.
PMID: 30445835 [PubMed - as supplied by publisher]
Source: Clinical Trials - November 16, 2018 Category: Research Authors: Cocoros NM, Pokorney SD, Haynes K, Garcia C, Al-Khalidi HR, Al-Khatib SM, Archdeacon P, Goldsack JC, Harkins T, Lin ND, Martin D, McCall D, Nair V, Parlett L, Temple R, McMahill-Walraven C, Granger CB, Platt R Tags: Clin Trials Source Type: research
