Mandibular Advancement Devices in Patients with Symptoms of Obstructive Sleep Apnea: A Review.

Mandibular Advancement Devices in Patients with Symptoms of Obstructive Sleep Apnea: A Review. Adv Exp Med Biol. 2019 Jan 29;: Authors: Wojda M, Jurkowski P, Lewandowska A, Mierzwińska-Nastalska E, Kostrzewa-Janicka J Abstract Obstructive sleep apnea (OSA) is a sleep disorder resulting from the repetitive narrowing and collapse of the upper respiratory tract. The results of previous epidemiological studies confirm a significant impact of OSA on the health situation around the world. Untreated OSA is associated with many adverse health effects, such as hypertension, coronary artery disease, stroke, atrial fibrillation, congestive heart failure, and daytime sleepiness. Excessive mortality of OSA patients, especially in men under 50 years of age, associated with advanced disease, obesity, cardiovascular complications, and a greater risk of road accidents, requires an urgent extension of the diagnostic-therapeutic database dealing with this problem. It is estimated that in the adult population, OSA occurs in 4% of men and in 2% of women. In recent years, intraoral devices have become an increasingly common method of OSA and snoring treatment. Nevertheless, the use of devices producing continuous positive airway pressure (CPAP) remains the most effective treatment method. However, intraoral devices have the advantage of not requiring a source of electricity and are less troublesome in everyday use. Intraoral devices are well tolerated by the majority of ...
Source: Advances in Experimental Medicine and Biology - Category: Research Tags: Adv Exp Med Biol Source Type: research

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Authors: Finley JR, Wixted JT, Roediger HL Abstract Recent research in the eyewitness identification literature has investigated whether simultaneous or sequential lineups yield better discriminability. In standard eyewitness identification experiments, subjects view a mock-crime video and then are tested only once, requiring large samples for adequate power. However, there is no reason why theories of simultaneous versus sequential lineup performance cannot be tested using more traditional recognition memory tasks. In two experiments, subjects studied DRM (Deese-Roediger-McDermott) word lists (e.g., bed, rest, tir...
Source: Memory and Cognition - Category: Neuroscience Tags: Mem Cognit Source Type: research
Conclusion: Here, we reveal several Nrf2 dose-responsive miRNA loci harboring putative upstream antioxidant response elements (AREs). Intriguingly, Nrf2-mediated miRNA responses were distinctly enriched for post-transcriptional regulation of cardiac-specific mRNAs. Altogether, these data reveal Nrf2 as a potent regulator of cardiac miRNA expression and provide novel candidates for future mechanistic investigation into the relationship between myocardial redox status and pathophysiology.
Source: GEO: Gene Expression Omnibus - Category: Genetics & Stem Cells Tags: Non-coding RNA profiling by high throughput sequencing Mus musculus Source Type: research
Conclusion: Here, we reveal several Nrf2 dose-responsive miRNA loci harboring putative upstream antioxidant response elements (AREs). Intriguingly, Nrf2-mediated miRNA responses were distinctly enriched for post-transcriptional regulation of cardiac-specific mRNAs. Altogether, these data reveal Nrf2 as a potent regulator of cardiac miRNA expression and provide novel candidates for future mechanistic investigation into the relationship between myocardial redox status and pathophysiology.
Source: GEO: Gene Expression Omnibus - Category: Genetics & Stem Cells Tags: Expression profiling by high throughput sequencing Mus musculus Source Type: research
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Source: GEO: Gene Expression Omnibus - Category: Genetics & Stem Cells Tags: Expression profiling by array Mus musculus Source Type: research
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Source: GEO: Gene Expression Omnibus - Category: Genetics & Stem Cells Tags: Expression profiling by array Non-coding RNA profiling by array Mus musculus Source Type: research
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Source: GEO: Gene Expression Omnibus - Category: Genetics & Stem Cells Tags: Expression profiling by high throughput sequencing Mus musculus Source Type: research
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Source: GEO: Gene Expression Omnibus - Category: Genetics & Stem Cells Tags: Expression profiling by high throughput sequencing Mus musculus Source Type: research
The 2020 Kidney Disease: Improving Global Outcomes (KDIGO) Clinical Practice Guideline on the Evaluation and Management of Candidates for Kidney Transplantation is intended to assist health care professionals worldwide who evaluate and manage potential candidates for deceased or living donor kidney transplantation. This guideline addresses general candidacy issues such as access to transplantation, patient demographic and health status factors, immunological and psychosocial assessment. The roles of various risk factors and comorbid conditions governing an individual’s suitability for transplantation such as adherenc...
Source: Transplantation - Category: Transplant Surgery Tags: Reviews Source Type: research
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Source: Transplantation - Category: Transplant Surgery Tags: Original Clinical Science—General Source Type: research
Source: Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy - Category: Endocrinology Tags: Diabetes, Metabolic Syndrome and Obesity: Targets and Therapy Source Type: research
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