Filtered By:
Condition: Stroke
Procedure: Perfusion

This page shows you your search results in order of relevance. This is page number 13.

Order by Relevance | Date

Total 4550 results found since Jan 2013.

Reduced Ischemic Lesion Growth with Heparin in Acute Ischemic Stroke
Objective: The role of heparin in acute ischemic stroke is controversial. We investigated the effect of heparin on ischemic lesion growth. Methods: Data were analyzed on nonthrombolyzed ischemic stroke patients in whom diffusion-weighted imaging (DWI)/perfusion-weighted imaging (PWI) MRI was performed less than 12hours of last known well and showed a PWI-DWI lesion mismatch, and who underwent follow-up neuroimaging at least 4days after admission. Lesion growth was assessed by (1) absolute lesion growth and (2) percentage mismatch lost (PML).
Source: Journal of Stroke and Cerebrovascular Diseases - March 28, 2019 Category: Neurology Authors: Eva A. Rocha, Ruijun Ji, Hakan Ay, Zixiao Li, Ethem Murat Arsava, Gisele S. Silva, Alma Gregory Sorensen, Ona Wu, Aneesh B. Singhal Source Type: research

Impaired Collateral Flow in Pial Arterioles of Aged Rats During Ischemic Stroke
AbstractCerebral collateral circulation and age are critical factors in determining outcome from acute ischemic stroke. Aging may lead to rarefaction of cerebral collaterals, and thereby accelerate ischemic injury by reducing penumbral blood flow. Dynamic changes in pial collaterals after onset of cerebral ischemia may vary with age but have not been extensively studied. Here, laser speckle contrast imaging (LSCI) and two-photon laser scanning microscopy (TPLSM) were combined to monitor cerebral pial collaterals between the anterior cerebral artery (ACA) and the middle cerebral artery (MCA) in young adult and aged male Spr...
Source: Translational Stroke Research - June 14, 2019 Category: Neurology Source Type: research

Impaired Cerebrovascular Autoregulation in Large Vessel Occlusive Stroke after Successful Mechanical Thrombectomy: A Prospective Cohort Study
Introduction: Successful thrombectomy improves morbidity and mortality after stroke. The present prospective, observational cohort study investigated a potential correlation between the successful restoration of tissue perfusion by mechanical thrombectomy and intact cerebrovascular autoregulation (CA). Objective: Status of CA in patients with large vessel occlusive stroke after thrombectomy. Methods: After thrombectomy CA was measured using transcranial Doppler ultrasound. For this purpose a moving correlation index (Mxa) based on spontaneous arterial blood pressure fluctuations and corresponding cerebral blood flow veloci...
Source: Journal of Stroke and Cerebrovascular Diseases - January 1, 2020 Category: Neurology Authors: Marco Meyer, Martin Juenemann, Tobias Braun, Ingo Schirotzek, Christian Tanislav, Kristin Engelhard, Patrick Schramm Source Type: research

The Value of Whole-Brain Perfusion Parameters Combined with Multiphase Computed Tomography Angiography in Predicting Hemorrhagic Transformation in Ischemic Stroke
Objective: To explore the value of whole-brain perfusion parameters combined with multiphase computed tomography angiography (MP-CTA) in predicting the hemorrhagic transformation (HT) of ischemic stroke. Methods: A total of 64 patients with ischemic stroke who underwent noncontrast computed tomography, computed tomography perfusion imaging, and computed tomography angiography before treatment from August 2017 to June 2019 were included retrospectively. The perfusion parameters cerebral blood volume (CBV), cerebral blood flow (CBF), time to peak (TTP), mean transit time (MTT), time to maximum (Tmax), and permeability surfac...
Source: Journal of Stroke and Cerebrovascular Diseases - February 13, 2020 Category: Neurology Authors: Xiang Li, Huan Liu, Wenbing Zeng, Xinghua Liu, Yun Wen, Qiuxia Xiong, Ran Yang Source Type: research

Hemichorea as Presentation of Acute Cortical Ischemic Stroke. Case Series and Review of the Literature
We report 4 cases of acute ischemic cortical strokes presenting as hemichorea, with the infarction being limited to the parietal and insular cortex in perfusion computed tomography scans and magnetic resonance imaging.
Source: Journal of Stroke and Cerebrovascular Diseases - August 11, 2020 Category: Neurology Authors: Álvaro Carbayo, Jordi Sarto, Daniel Santana, Yaroslau Compta, Xabier Urra Source Type: research

Asymmetry of medullary veins on multiphase CT-angiography in patients with acute ischemic stroke
The management of acute ischemic stroke (AIS) has rapidly evolved over the last decade with the advancement in neuroimaging selection methods and endovascular treatment techniques. CT perfusion (CTP) with automated post-processing is the most widely used technique for extended-time window selection of patients for intra-arterial interventions based on recent clinical trials.1,2 CTP provides predictive information about stroke outcome, however the predictive ability remains moderate with area under the curve (AUC) approximately 0.6.
Source: Journal of Stroke and Cerebrovascular Diseases - August 11, 2020 Category: Neurology Authors: A.A. Drozdov, R. Javan, C.R. Leon Guerrero, A.D. Sparks, M.R. Taheri Source Type: research

Standardized Fabrication Method of Human-Derived Emboli with Histologic and Mechanical Quantification for Stroke Research
Rapid and immediate perfusion of ischemic brain tissue with mechanical thrombectomy devices has become the cornerstone treatment in large vessel occlusion (LVO) stroke.1 Although stent retrievers and suction catheters have proven their value in large clinical trials, they have several limitations, including low rates of first-pass recanalization2 and low overall rates of complete recanalization.3 The development of new technologies to more rapidly and completely recanalize LVO in stroke relies on accurate testing phantoms and embolus analogs (EAs).
Source: Journal of Stroke and Cerebrovascular Diseases - October 14, 2020 Category: Neurology Authors: Yang Liu, Adithya S. Reddy, Joshua Cockrum, Miranda C. Ajulufoh, Yihao Zheng, Albert J. Shih, Aditya S. Pandey, Luis E. Savastano Source Type: research

Effect of Sex on Clinical Outcome and Imaging after Endovascular Treatment of Large-Vessel Ischemic Stroke
In this study we assess the effect of sex on radiological and functional outcomes in EVT-treated acute stroke patients and determine if differences in baseline perfusion status between men and women might account for differences in outcomes.
Source: Journal of Stroke and Cerebrovascular Diseases - November 21, 2020 Category: Neurology Authors: Jelle Demeestere, S ören Christensen, Michael Mlynash, Christian Federau, Gregory W. Albers, Robin Lemmens, Maarten G. Lansberg Source Type: research

Caveats to Acute Imaging for Acute Stroke in the Setting of Venoarterial Extracorporeal Membrane Oxygenation
Venoarterial extracorporeal membrane oxygenation (VA-ECMO) is increasingly used for cardiorespiratory support in medically refractory cases. The high rate of neurologic complications, specifically cerebrovascular disorders such as acute ischemic stroke, in VA-ECMO patients frequently prompts the acquisition of neuroimaging studies such as CT with angiography and perfusion imaging. Clinicians must be familiar with the ECMO-related artifacts when interpreting such studies. Here, we describe a case of asymmetric contrast opacification in a VA-ECMO patient with axillary artery cannulation.
Source: Neurology Clinical Practice - December 13, 2021 Category: Neurology Authors: Viamonte, M. A., Yu, J., Echevarria, F. D., Nagae, L., Youn, T. S., Tahsili-Fahadan, P., Simpkins, A. N. Tags: Stroke in young adults, CT, All Cerebrovascular disease/Stroke Case Source Type: research

Endovascular reperfusion outcomes in patients with a stroke and low ASPECTS is highly dependent on baseline infarct volumes
Conclusions Outcomes may vary significantly in the same ASPECTS category depending on infarct volume. Patients with ASPECTS ≤5 but baseline infarct volumes ≤70 cc may achieve independence in nearly 40% of the cases and thus should not be excluded from treatment.
Source: Journal of NeuroInterventional Surgery - January 18, 2022 Category: Neurosurgery Authors: Bouslama, M., Barreira, C. M., Haussen, D. C., Rodrigues, G. M., Pisani, L., Frankel, M. R., Nogueira, R. G. Tags: Ischemic stroke Source Type: research

CT Perfusion Maps Improve Detection of M2-MCA Occlusions in Acute Ischemic Stroke
A growing body of literature supports mechanical thrombectomy-based endovascular therapy for M2-MCA occlusions in eligible patients with acute ischemic stroke (AIS).1 –5 This is because endovascular treatment for M2-MCA occlusions is technically feasible and leads to improved patient outcomes, despite a potential increased risk of hemorrhage.4,5 Not uncommonly, these patients undergo a single or multi-phase CT angiogram (CTA) study for LVO detection. In patient s who present in the late stroke window (6–24 h since last known normal), the CT Perfusion (CTP) study is generally performed along with a CTA study to aid in patient triage.
Source: Journal of Stroke and Cerebrovascular Diseases - April 14, 2022 Category: Neurology Authors: Girish Bathla, Ravishankar Pillenahalli Maheshwarappa, Neetu Soni, Minako Hayakawa, Sarv Priya, Edgar Samaniego, Santiago Ortega-Gutierrez, Colin P. Derdeyn Source Type: research

Hypoperfusion Intensity Ratio is Associated with Stroke Mechanism in Patients Undergoing Mechanical Thrombectomy
Hypoperfusion Intensity Ratio (HIR), defined as Tmax>10s/Tmax>6s on computed tomography perfusion (CTP), and stroke mechanisms have been independently correlated with angiographic collaterals and patient outcomes. Slowly developing atherosclerotic stenosis may foster collateral development, whereas cardioembolic occlusion may occur before collaterals mature. We hypothesized that favorable HIR is associated with large artery atherosclerosis (LAA) stroke mechanism and good clinical outcome.
Source: Journal of Stroke and Cerebrovascular Diseases - May 9, 2022 Category: Neurology Authors: Ahmad A. Ballout, Richard B Libman, Julia R. Schneider, Marc S. Ayoub, Jason J. Wang, Athos Patsalides, Jeffrey M Katz Source Type: research

Collateral-Core Ratio as a Novel Predictor of Clinical Outcomes in Acute Ischemic Stroke
AbstractThe interaction effect between collateral circulation and ischemic core size on stroke outcomes has been highlighted in acute ischemic stroke (AIS). However, biomarkers that assess the magnitude of this interaction are still lacking. We aimed to present a new imaging marker, the collateral-core ratio (CCR), to quantify the interaction effect between these factors and evaluate its ability to predict functional outcomes using machine learning (ML) in AIS. Patients with AIS caused by anterior circulation large vessel occlusion (LVO) were recruited from a prospective multicenter study. CCR was calculated as collateral ...
Source: Translational Stroke Research - July 25, 2022 Category: Neurology Source Type: research

Feasibility of deconvolution-based multiphase CT angiography perfusion maps in acute ischemic stroke: Simulation and concordance with CT perfusion
Integration of CT perfusion (CTP) with requisite non-contrast CT and CT angiography (CTA) stroke imaging may allow efficient stroke lesion volume measurement. Using surrogate images from CTP, we simulated the feasibility of using multiphase CTA (mCTA) to generate perfusion maps and assess target mismatch profiles.
Source: Journal of Stroke and Cerebrovascular Diseases - October 29, 2022 Category: Neurology Authors: Kevin J. Chung, Alexander V. Khaw, Sachin K. Pandey, Donald H. Lee, Jennifer L. Mandzia, Ting-Yim Lee Source Type: research

Autonomic function may mediate the neuroprotection of remote ischemic postconditioning in stroke: A randomized controlled trial
Acute ischemic stroke(AIS) is one of the leading causes of death and long-lasting disability on a global level, with an increased global burden in the past two decades.1,2 Early restoration of blood flow is currently recognized as the most effective therapy for AIS. However, rapid reperfusion after a certain period of ischemia could paradoxically induce ischemia-perfusion injury (IRI), which can promote neurovascular inflammation by inducing the generation of cytokines, and thus aggravate stroke severity and adverse neurological outcomes.
Source: Journal of Stroke and Cerebrovascular Diseases - June 15, 2023 Category: Neurology Authors: Hao Liang, Richun Ye, Xiaopei Zhang, Huanwen Ye, Wenwei Ouyang, Shuang Cai, Lin Wei Source Type: research