Autonomic function may mediate the neuroprotection of remote ischemic postconditioning in stroke: A randomized controlled trial
Acute ischemic stroke(AIS) is one of the leading causes of death and long-lasting disability on a global level, with an increased global burden in the past two decades.1,2 Early restoration of blood flow is currently recognized as the most effective therapy for AIS. However, rapid reperfusion after a certain period of ischemia could paradoxically induce ischemia-perfusion injury (IRI), which can promote neurovascular inflammation by inducing the generation of cytokines, and thus aggravate stroke severity and adverse neurological outcomes.
Source: Journal of Stroke and Cerebrovascular Diseases - Category: Neurology Authors: Hao Liang, Richun Ye, Xiaopei Zhang, Huanwen Ye, Wenwei Ouyang, Shuang Cai, Lin Wei Source Type: research