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Condition: Stroke
Procedure: Perfusion

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Total 4550 results found since Jan 2013.

Clinical Use of Computed Tomographic Perfusion for the Diagnosis and Prediction of Lesion Growth in Acute Ischemic Stroke
Conclusions: In real-world use, acute imaging with CTP did not predict stroke or DWI lesions with sufficient accuracy. Our findings argue against the use of CTP for screening AIS patients until real-world implementations match the accuracy reported from specialized research centers.
Source: Journal of Stroke and Cerebrovascular Diseases - December 17, 2012 Category: Neurology Authors: Branko N. Huisa, William P. Neil, Ronald Schrader, Marcel Maya, Benedict Pereira, Nhu T. Bruce, Patrick D. Lyden Tags: Original Articles Source Type: research

Physical Activity Correlates with Arterial Stiffness in Community-dwelling Individuals with Stroke
Conclusions: We found that arterial stiffness is elevated in community-dwelling, ambulatory individuals with stroke relative to healthy people. Multivariable regression analysis suggests that aerobic capacity (VO2 peak) may contribute to the variance of cfPWV after accounting for the effects of age and medication use. Whether intense risk modification and augmented physical activity will improve arterial stiffness in this population remains to be determined.
Source: Journal of Stroke and Cerebrovascular Diseases - March 8, 2013 Category: Neurology Authors: Ada Tang, Janice J. Eng, Penelope M. Brasher, Kenneth M. Madden, Azam Mohammadi, Andrei V. Krassioukov, Teresa S.M. Tsang Tags: Original Articles Source Type: research

Intravenous Thrombolysis Resulting In Acute Ischemic Stroke Recanalization Can Lead To Cerebral Hyperperfusion Syndrome (P7.123)
Conclusion- Cerebral hyperperfusion syndrome after intravenous thrombolysis in acute ischemic stroke should be suspected in patients that achieve arterial recanalization and develop unexplained new neuropsychiatric manifestations.Disclosure: Dr. Ong has nothing to disclose. Dr. Yeo has nothing to disclose. Dr. Ting has nothing to disclose. Dr. Sinha has nothing to disclose. Dr. Teoh has nothing to disclose. Dr. Chan has nothing to disclose. Dr. Seet has nothing to disclose. Dr. Sharma has nothing to disclose.
Source: Neurology - April 9, 2014 Category: Neurology Authors: Ong, J., Yeo, L., Ting, E., Sinha, A., Teoh, H. L., Chan, B., Seet, C. S., Sharma, V. Tags: Cerebrovascular Disease and Interventional Neurology: Issues in Acute Stroke Treatment Source Type: research

Optical Bedside Monitoring of Cerebral Blood Flow in Acute Ischemic Stroke Patients During Head-of-Bed Manipulation Clinical Sciences
Conclusions— A lower HOB angle results in an increase in cortical CBF without a significant change in arterial flow velocity in AIS, but there is variability across patients in this response. Bedside CBF monitoring with diffuse correlation spectroscopy provides a potential means to individualize interventions designed to optimize CBF in AIS.
Source: Stroke - April 28, 2014 Category: Neurology Authors: Favilla, C. G., Mesquita, R. C., Mullen, M., Durduran, T., Lu, X., Kim, M. N., Minkoff, D. L., Kasner, S. E., Greenberg, J. H., Yodh, A. G., Detre, J. A. Tags: Brain Circulation and Metabolism, Doppler ultrasound, Transcranial Doppler etc. Clinical Sciences Source Type: research

Vertebral Artery Hypoplasia: Frequency and Effect on Cerebellar Blood Flow Characteristics Clinical Sciences
Conclusions— VAH is a frequent vascular variant that can lead to a relative regional hypoperfusion in the PICA territory. Additional research should clarify the pathophysiological role of VAH in PCI.
Source: Stroke - April 28, 2014 Category: Neurology Authors: Thierfelder, K. M., Baumann, A. B., Sommer, W. H., Armbruster, M., Opherk, C., Janssen, H., Reiser, M. F., Straube, A., von Baumgarten, L. Tags: Brain Circulation and Metabolism, Computerized tomography and Magnetic Resonance Imaging, Pathology of Stroke, Risk Factors for Stroke Clinical Sciences Source Type: research

Improved Hemodynamic Parameters in Middle Cerebral Artery Infarction After Decompressive Craniectomy Clinical Sciences
Conclusions— DC improves cerebral hemodynamics in patients with malignant middle cerebral artery infarction, and the level of improvement is related to outcome. However, some patients did not seem to experience any additional hemodynamic benefit, suggesting that perfusion CT may play a role as a prognostic tool in patients undergoing DC after ischemic stroke.
Source: Stroke - April 28, 2014 Category: Neurology Authors: Amorim, R. L., de Andrade, A. F., Gattas, G. S., Paiva, W. S., Menezes, M., Teixeira, M. J., Bor-Seng-Shu, E. Tags: Acute Cerebral Infarction, Computerized tomography and Magnetic Resonance Imaging, Other Stroke Treatment - Surgical Clinical Sciences Source Type: research

Crossed Cerebellar Diaschisis Detected by Arterial Spin-Labeled Perfusion Magnetic Resonance Imaging in Subacute Ischemic Stroke
Conclusions: With advantages in easy acquisition and no radiation, ASL-MRI seems to be an ideal tool for the detection and follow-up of CCD.
Source: Journal of Stroke and Cerebrovascular Diseases - September 1, 2014 Category: Neurology Authors: Shuai Chen, Min Guan, Hao-Jun Lian, Li-Jia Ma, Jun-Kui Shang, Shuang He, Ming-Ming Ma, Mi-Lan Zhang, Zi-Yuan Li, Mei-Yun Wang, Da-Peng Shi, Jie-Wen Zhang Tags: Original Articles Source Type: research

Pathophysiological Role of Global Cerebral Ischemia following Subarachnoid Hemorrhage: The Current Experimental Evidence.
Authors: Plesnila N Abstract Subarachnoid hemorrhage (SAH) is the subtype of stroke with one of the highest mortality rates and the least well-understood pathophysiologies. One of the very early events which may occur after SAH is a significant decrease of cerebral perfusion pressure (CPP) caused by the excessive increase of intracranial pressure during the initial bleeding. A severely decreased CPP results in global cerebral ischemia, an event also occurring after cardiac arrest. The aim of the current paper is to review the pathophysiological events occurring in experimental models of SAH and global cerebral isch...
Source: Stroke Research and Treatment - December 2, 2014 Category: Neurology Tags: Stroke Res Treat Source Type: research

Primary Acute Stroke Thrombectomy In 3 Hours From Middle Cerebral Artery Occlusion- A pilot Study (P4.291)
Conclusion: Our pilot study demonstrates that primary AIS thrombectomy for MCA occlusion with LCB is not only feasible and safe, but associated with complete recanalization and good functional outcome. Larger randomized controlled studies are needed.Disclosure: Dr. Lodi has nothing to disclose. Dr. Reddy has nothing to disclose. Dr. Devasenapathy has nothing to disclose. Dr. Shehadeh has nothing to disclose. Dr. Hourini has nothing to disclose. Dr. Chou has nothing to disclose.
Source: Neurology - April 8, 2015 Category: Neurology Authors: Lodi, Y., Reddy, V., Devasenapathy, A., Shehadeh, K., Hourini, A., Chou, C.-A. Tags: Cerebrovascular Disease and Interventional Neurology: Acute Ischemic Stroke Treatment Source Type: research

Value of Whole Brain Computed Tomography Perfusion for Predicting Outcome After TIA or Minor Ischemic Stroke
About 15% of patients with transient ischemic attack (TIA) or minor ischemic stroke have functional impairment after 3 months. We studied the role of whole brain computed tomography perfusion (WB-CTP) in the emergency diagnosis of TIA or minor stroke in predicting disability at 3 months.
Source: Journal of Stroke and Cerebrovascular Diseases - July 2, 2015 Category: Neurology Authors: Ido R. van den Wijngaard, Ale Algra, Geert J. Lycklama à Nijeholt, Jelis Boiten, Marieke J.H. Wermer, Marianne A.A. van Walderveen Source Type: research

Clinical and radiologic reversal of stroke-like episodes in MELAS with high-dose L-arginine
Mitochondrial encephalomyopathy, lactic acidosis, and stroke-like episodes (MELAS) syndrome (MT-TL1 gene) is a progressive neurologic disorder with stroke-like episodes (SLEs), which are recurrent neurologic deficits resembling vasoocclusive strokes.1 However, SLEs are not restricted to vascular territories and have a predilection for the occipital and posterior parietal and temporal cortices,2 may evolve subacutely over hours to days,3 and have greater potential for reversibility.4 Their pathophysiology is incompletely understood. Current literature suggests a combination of neuronal mitochondrial energy failure and cereb...
Source: Neurology - July 13, 2015 Category: Neurology Authors: Siddiq, I., Widjaja, E., Tein, I. Tags: MRI, Other cerebrovascular disease/ Stroke, Mitochondrial disorders; see Genetics/Mitochondrial disorders, All Pediatric CLINICAL/SCIENTIFIC NOTES Source Type: research

Influence of Recanalization and Time of Cerebral Ischemia on Tissue Outcome after Endovascular Stroke Treatment on Computed Tomography Perfusion
The Alberta Stroke Program Early Computed Tomography Score (ASPECTS) has been proposed as a straightforward alternative to the less reliable visual estimation of tissue at risk. We evaluated the association between admission ASPECTS on computed tomography perfusion (CTP) parameter maps and final infarct ASPECTS in patients with acute ischemic stroke who were treated by endovascular therapy (eT) and compared the results with thrombolysis candidates treated conservatively.
Source: Journal of Stroke and Cerebrovascular Diseases - July 14, 2015 Category: Neurology Authors: Anselm Angermaier, Alexander V. Khaw, Michael Kirsch, Christof Kessler, Soenke Langner Source Type: research

Response to endovascular reperfusion is not time-dependent in patients with salvageable tissue
Conclusion: The association between endovascular reperfusion and improved functional and radiologic outcomes is not time-dependent in patients with a perfusion-diffusion mismatch. Proof that patients with mismatch benefit from endovascular therapy in the late time window should come from a randomized placebo-controlled trial.
Source: Neurology - August 24, 2015 Category: Neurology Authors: Lansberg, M. G., Cereda, C. W., Mlynash, M., Mishra, N. K., Inoue, M., Kemp, S., Christensen, S., Straka, M., Zaharchuk, G., Marks, M. P., Bammer, R., Albers, G. W., For the Diffusion and Perfusion Imaging Evaluation for Understanding Stroke Evolution 2 ( Tags: MRI, All Cerebrovascular disease/Stroke, Clinical trials Observational study (Cohort, Case control) ARTICLE Source Type: research

Feasibility and Safety of Using External Counterpulsation to Augment Cerebral Blood Flow in Acute Ischemic Stroke—The Counterpulsation to Upgrade Forward Flow in Stroke (CUFFS) Trial
Background: External counterpulsation (ECP) increases perfusion to a variety of organs and may be helpful for acute stroke. Methods: We conducted a single-blinded, prospective, randomized controlled feasibility and safety trial of ECP for acute middle cerebral artery (MCA) ischemic stroke. Twenty-three patients presenting within 48 hours of symptom onset were randomized into one of two groups. One group was treated with ECP for 1 hour at a pressure of up to 300 mmHg (“full pressure”). During the procedure, we also determined the highest possible pressure that would augment MCA mean flow velocity (MFV) by 15%.
Source: Journal of Stroke and Cerebrovascular Diseases - September 5, 2015 Category: Neurology Authors: Kama Z. Guluma, David S. Liebeskind, Rema Raman, Karen S. Rapp, Karin B. Ernstrom, Andrei V. Alexandrov, Reza B. Shahripour, Kristian Barlinn, Sidney Starkman, Ileana D. Grunberg, Thomas M. Hemmen, Brett C. Meyer, Anne W. Alexandrov Source Type: research

A Simple Geometric Assessment of Perfusion Lesion Volume at Hyperacute Stage of Ischemic Stroke in Patients with Symptomatic Steno-Occlusion of Major Cerebral Arteries and Risk of Subsequent Cerebral Ischemic Events
Our objective is to elucidate the association of baseline perfusion lesion volume on perfusion-weighted magnetic resonance imaging (PWI) obtained at hyperacute stage of ischemic stroke with subsequent cerebral ischemic events (SIEs) in patients with symptomatic steno-occlusion of major cerebral arteries. Using a prospective stroke registry database, patients arriving within 24 hours of onset with symptomatic steno-occlusion of major supratentorial cerebral arteries were identified. On baseline PWI, time-to-peak lesion volume (TTP-LV) was determined by a simple geometric method and dichotomized into the highest tertile (la...
Source: Journal of Stroke and Cerebrovascular Diseases - October 14, 2015 Category: Neurology Authors: Jihoon Kang, Cheolkyu Jung, Nayoung Kim, Yoo Ri Son, Byungse Choi, Jae-Hyoung Kim, Ji Sung Lee, Juneyoung Lee, Jun Lee, Myung Suk Jang, Mi Hwa Yang, Moon-Ku Han, Hee-Joon Bae Source Type: research