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Condition: Stroke
Procedure: Perfusion

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Total 4550 results found since Jan 2013.

Postischemic hyperperfusion on arterial spin labeled perfusion MRI is linked to hemorrhagic transformation in stroke
Noriko Salamon & Danny JJ Wang
Source: Journal of Cerebral Blood Flow and Metabolism - March 31, 2015 Category: Neuroscience Authors: Songlin YuDavid S LiebeskindSumit DuaHolly WilhalmeDavid ElashoffXin J QiaoJeffry R AlgerNerses SanossianSidney StarkmanLatisha K AliFabien ScalzoXin LouBryan YooJeffrey L SaverNoriko SalamonDanny JJ Wang Tags: arterial spin labeling (ASL) acute ischemic stroke (AIS) hemorrhagic transformation (HT) hyperperfusion Source Type: research

Why are most stroke patients deemed poor candidates for intraaterial therapy? A prospective study (P4.306)
Conclusion: The majority of patients presenting to a large tertiary referral center with AIS due to a large vessel occlusion were found to be poor IA candidates, with more than half excluded for a single reason. Such data addressing the volume and proportion of patients found ineligible for IA therapy in real-world practice can help target efforts to develop new interventional options and improve future clinical trial design.Disclosure: Dr. Damania has nothing to disclose. Dr. Noto has nothing to disclose. Dr. Kung has nothing to disclose. Dr. Liew has nothing to disclose. Dr. Finley has nothing to disclose. Dr. Mangla has...
Source: Neurology - April 8, 2015 Category: Neurology Authors: Damania, D., Noto, A., Kung, N., Liew, J., Finley, H., Mangla, R., Miranpuri, A., Sahin, B., Jahromi, B. Tags: Cerebrovascular Disease and Interventional Neurology: Acute Interventional Treatment for Ischemic Stroke Source Type: research

M2 occlusions as targets for endovascular therapy: comprehensive analysis of diffusion/perfusion MRI, angiography, and clinical outcomes
Conclusions If suitable as targets of ET, M2 occlusions should be given the same consideration as M1 occlusions.
Source: Journal of NeuroInterventional Surgery - June 11, 2015 Category: Neurosurgery Authors: Sheth, S. A., Yoo, B., Saver, J. L., Starkman, S., Ali, L. K., Kim, D., Gonzalez, N. R., Jahan, R., Tateshima, S., Duckwiler, G., Vinuela, F., Liebeskind, D. S., for the UCLA Comprehensive Stroke Center Tags: Ischemic stroke Source Type: research

Multimodal imaging reveals temporal and spatial microglia and matrix metalloproteinase activity after experimental stroke
chäfers, Lydia M Sorokin, Michael T Kuhlmann & Andreas H Jacobs
Source: Journal of Cerebral Blood Flow - July 1, 2015 Category: Neurology Authors: Bastian ZinnhardtThomas VielLydia WachsmuthAlexis VrachimisStefan WagnerHans-Jörg BreyholzAndreas FaustSven HermannKlaus KopkaCornelius FaberFrédéric DolléSabina PappataAnna M PlanasBertrand TavitianMichael SchäfersLydia M SorokinMichael T KuhlmannAn Tags: microglia matrix metalloproteases perfusion positron emission tomography stroke Source Type: research

Therapeutically Targeting Tumor Necrosis Factor-{alpha}/Sphingosine-1-Phosphate Signaling Corrects Myogenic Reactivity in Subarachnoid Hemorrhage Basic Sciences
Conclusions— Vascular smooth muscle cell TNFα and sphingosine-1-phosphate signaling significantly enhance cerebral artery tone in SAH; anti-TNFα and anti–sphingosine-1-phosphate treatment may significantly improve clinical outcome.
Source: Stroke - July 27, 2015 Category: Neurology Authors: Yagi, K., Lidington, D., Wan, H., Fares, J. C., Meissner, A., Sumiyoshi, M., Ai, J., Foltz, W. D., Nedospasov, S. A., Offermanns, S., Nagahiro, S., Macdonald, R. L., Bolz, S.-S. Tags: Animal models of human disease, Acute Cerebral Hemorrhage, Brain Circulation and Metabolism, Other Stroke Treatment - Medical, Other Vascular biology Basic Sciences Source Type: research

Noninvasive cerebral oximetry during endovascular therapy for acute ischemic stroke: an observational study
Julian Bösel
Source: Journal of Cerebral Blood Flow - August 5, 2015 Category: Neurology Authors: Christian HametnerPredrag StanarcevicSibylle StampflStefan RohdeRoland VeltkampJulian Bösel Tags: acute ischemic stroke medial cerebral artery occlusion near-infrared spectroscopy perfusion regional oxygen saturation thrombectomy Source Type: research

Maximal Admission Core Lesion Compatible With Favorable Outcome in Acute Stroke Patients Undergoing Endovascular Procedures Clinical Sciences
Conclusions— Admission lesion core is associated with final infarct volume and is a strong predictor of favorable outcome. MALCOM according to imaging modality and patient age could be set and used on admission to select candidates for endovascular procedures.
Source: Stroke - September 28, 2015 Category: Neurology Authors: Ribo, M., Tomasello, A., Lemus, M., Rubiera, M., Vert, C., Flores, A., Coscojuela, P., Pagola, J., Rodriguez-Luna, D., Bonet, S., Muchada, M., Rovira, A., Molina, C. A. Tags: CT and MRI, Emergency treatment of Stroke, Computerized tomography and Magnetic Resonance Imaging Clinical Sciences Source Type: research

Multimodal imaging reveals temporal and spatial microglia and matrix metalloproteinase activity after experimental stroke
chäfers, Lydia M Sorokin, Michael T Kuhlmann & Andreas H Jacobs
Source: Journal of Cerebral Blood Flow and Metabolism - October 30, 2015 Category: Neuroscience Authors: Bastian ZinnhardtThomas VielLydia WachsmuthAlexis VrachimisStefan WagnerHans-Jörg BreyholzAndreas FaustSven HermannKlaus KopkaCornelius FaberFrédéric DolléSabina PappataAnna M PlanasBertrand TavitianMichael SchäfersLydia M SorokinMichael T KuhlmannAn Tags: microglia matrix metalloproteases perfusion positron emission tomography stroke Source Type: research

Noninvasive cerebral oximetry during endovascular therapy for acute ischemic stroke: an observational study
Julian Bösel
Source: Journal of Cerebral Blood Flow and Metabolism - October 30, 2015 Category: Neuroscience Authors: Christian HametnerPredrag StanarcevicSibylle StampflStefan RohdeRoland VeltkampJulian Bösel Tags: acute ischemic stroke medial cerebral artery occlusion near-infrared spectroscopy perfusion regional oxygen saturation thrombectomy Source Type: research

Fluid-Attenuated Inversion Recovery Vascular Hyperintensities-Diffusion-Weighted Imaging Mismatch Identifies Acute Stroke Patients Most Likely to Benefit From Recanalization Clinical Sciences
Conclusion— The FVH-DWI mismatch may rapidly identify patients with proximal occlusion most likely to benefit from recanalization.
Source: Stroke - January 25, 2016 Category: Neurology Authors: Legrand, L., Tisserand, M., Turc, G., Edjlali, M., Calvet, D., Trystram, D., Roca, P., Naggara, O., Mas, J.-L., Meder, J.-F., Baron, J.-C., Oppenheim, C. Tags: Computerized Tomography (CT), Magnetic Resonance Imaging (MRI), Treatment, Ischemic Stroke Clinical Sciences Source Type: research

Inter-rater Agreement in Three Perfusion-Computed Tomography Evaluation Methods before Endovascular Therapy for Acute Ischemic Stroke
There is ongoing debate on which method of perfusion computed tomography (PCT) evaluation in ischemic stroke is the most appropriate for improved selection of patients for endovascular treatment. We sought to test different assessment methods for inter-rater reliability.
Source: Journal of Stroke and Cerebrovascular Diseases - February 2, 2016 Category: Neurology Authors: A.V. Khaw, A. Angermaier, P. Michel, M. Kirsch, C. Kessler, S. Langner Source Type: research

Good Clinical and Radiological Correlation from Standard Perfusion Computed Tomography Accurately Identifies Salvageable Tissue in Ischemic Stroke
It has been debated whether the penumbral pattern, as identified using multimodal imaging, is a specific marker of tissue viability in ischemic stroke. We assessed whether perfusion computed tomography (PCT) accurately identifies salvageable tissue and helps predict postreperfusion outcomes.
Source: Journal of Stroke and Cerebrovascular Diseases - February 5, 2016 Category: Neurology Authors: Michal M. Kawiorski, Agustina Vicente, Daniel Lourido, Alfonso Muriel, Eduardo Fandiño, José C. Méndez, Víctor Sánchez-González, Alba Aguado, Rodrigo Álvarez-Velasco, María Alonso de Leciñana Source Type: research

Thrombus Length Estimation on Delayed Gadolinium-Enhanced T1 Clinical Sciences
Conclusions— The dGE-T1, obtained by simply adjusting scanning order in multimodal magnetic resonance imaging protocol, is a useful tool for thrombus length estimation and middle cerebral artery recanalization prediction after IVT.
Source: Stroke - February 22, 2016 Category: Neurology Authors: Yan, S., Chen, Q., Xu, M., Sun, J., Liebeskind, D. S., Lou, M. Tags: Angiography, Ischemic Stroke Clinical Sciences Source Type: research

Cerebral perfusion in stroke-like migraine attacks after radiation therapy syndrome
We present 2 patients with recurrent attacks of SMART syndrome with increased cerebral blood volume in affected regions and abnormal vascular reactivity on transcranial Doppler ultrasound, suggesting a potential mechanism.
Source: Neurology - February 22, 2016 Category: Neurology Authors: Olsen, A. L., Miller, J. J., Bhattacharyya, S., Voinescu, P. E., Klein, J. P. Tags: MRI, All Clinical Neurology, All Cerebrovascular disease/Stroke, Radiation therapy-tumor CLINICAL/SCIENTIFIC NOTES Source Type: research

Stroke Presentation of Acute Type A Aortic Dissection with 100% Perfusion-Weighted Imaging–Diffusion-Weighted Imaging Mismatch: A Call for Urgent Action
Acute stroke in the setting of acute type A aortic dissection is not rare and may contraindicate immediate surgery. Evaluating irreversible brain damage is critical in this setting and magnetic resonance imaging is a key determinant in the decision of selecting surgical over medical treatment for these patients.
Source: Journal of Stroke and Cerebrovascular Diseases - March 7, 2016 Category: Neurology Authors: Gilles Amr, Gregoire Boulouis, Nicolas Bricout, Thomas Modine, Georges Fayad, Pierre Aguettaz, Mohamad Koussa Tags: Case Studies Source Type: research