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Condition: Stroke
Procedure: Perfusion

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Total 4550 results found since Jan 2013.

Increasing Use of Computed Tomographic Perfusion and Computed Tomographic Angiograms in Acute Ischemic Stroke From 2006 to 2010 Clinical Sciences
Conclusions— There was a marked increase in the rate of CTA and CTP studies in setting of acute ischemic stroke from 2006 to 2010, and both modalities were associated with increased reperfusion therapy use.
Source: Stroke - March 24, 2014 Category: Neurology Authors: Vagal, A., Meganathan, K., Kleindorfer, D. O., Adeoye, O., Hornung, R., Khatri, P. Tags: Computerized tomography and Magnetic Resonance Imaging Clinical Sciences Source Type: research

Intervention Stroke Assessment Scale for Eligibility in Endovascular Therapy (ISAS-ET) (P4.213)
Conclusion:In conclusion, the ISAS scoring system might help with the assessment of patient qualification for further endovascular treatment. Further prospective studies are warranted.Disclosure: Dr. Haitham has nothing to disclose. Dr. Bashir has nothing to disclose. Dr. Hussain has nothing to disclose. Dr. Misthal has nothing to disclose. Dr. Moussavi has nothing to disclose. Dr. Kirmani has nothing to disclose.
Source: Neurology - April 9, 2014 Category: Neurology Authors: Haitham, D., Bashir, A., Hussain, M., Misthal, S., Moussavi, M., Kirmani, J. Tags: Cerebrovascular Disease and Interventional Neurology: Acute Stroke Endovascular Source Type: research

Ischemic Stroke in Evolution: Predictive Value of Perfusion Computed Tomography
Background: Various perfusion computed tomography (PCT) parameters have been used to identify tissue at risk of infarction in the setting of acute stroke. The purpose of this study was to examine predictive value of the PCT parameters commonly used in clinical practice to define ischemic penumbra. The patient selection criterion aimed to exclude the effect of thrombolysis from the imaging data.Methods: Consecutive acute stroke patients were screened and a total of 18 patients who initially underwent PCT and CT angiogram (CTA) on presentation but did not qualify to receive thrombolytic therapy were selected. The PCT images ...
Source: Journal of Stroke and Cerebrovascular Diseases - August 19, 2013 Category: Neurology Authors: Amir Kheradmand, Marc Fisher, David Paydarfar Tags: Original Articles Source Type: research

Comparison of Computed Tomographic and Magnetic Resonance Perfusion Measurements in Acute Ischemic Stroke: Back-to-Back Quantitative Analysis Clinical Sciences
Conclusions— MRP and CTP can be used interchangeably if one uses Tmax measurement.
Source: Stroke - May 27, 2014 Category: Neurology Authors: Lin, L., Bivard, A., Levi, C. R., Parsons, M. W. Tags: Computerized tomography and Magnetic Resonance Imaging Clinical Sciences Source Type: research

Systemic Inflammation Impairs Tissue Reperfusion Through Endothelin-Dependent Mechanisms in Cerebral Ischemia Basic Sciences
Conclusions— These data suggest patients with a raised inflammatory profile may have persistent deficits in perfusion after reopening of an occluded vessel. Future therapeutic strategies to interrupt the mechanism identified could lead to enhanced recovery of penumbra in patients with a heightened inflammatory burden and a better outcome after stroke.
Source: Stroke - October 27, 2014 Category: Neurology Authors: Murray, K. N., Girard, S., Holmes, W. M., Parkes, L. M., Williams, S. R., Parry-Jones, A. R., Allan, S. M. Tags: Computerized tomography and Magnetic Resonance Imaging, Pathology of Stroke, Risk Factors for Stroke, Neuroprotectors Basic Sciences Source Type: research

The golden hour of stroke intervention: effect of thrombectomy procedural time in acute ischemic stroke on outcome
Conclusions Our findings suggest that extending mechanical thrombectomy procedure times beyond 60 min increases complications and device cost rates while worsening outcomes. These findings can serve as a time frame of when it is prudent to abort a failed thrombectomy case.
Source: Journal of NeuroInterventional Surgery - August 6, 2014 Category: Neurosurgery Authors: Spiotta, A. M., Vargas, J., Turner, R., Chaudry, M. I., Battenhouse, H., Turk, A. S. Tags: Ischemic stroke Source Type: research

White Matter Ischemic Changes in Hyperacute Ischemic Stroke: Voxel-Based Analysis Using Diffusion Tensor Imaging and MR Perfusion Clinical Sciences
Conclusions— Diffusion tensor imaging-FA was decreased in regions of WM infarction and increased in hypoperfused WM in patients with hyperacute acute ischemic stroke. The significantly increased FA values in the hypoperfused WM with Tmax≥5.4 s are suggestive of early ischemic microstructural changes.
Source: Stroke - January 26, 2015 Category: Neurology Authors: Nael, K., Trouard, T. P., Lafleur, S. R., Krupinski, E. A., Salamon, N., Kidwell, C. S. Tags: CT and MRI, Acute Cerebral Infarction, Computerized tomography and Magnetic Resonance Imaging Clinical Sciences Source Type: research

Limited Reliability of Computed Tomographic Perfusion Acute Infarct Volume Measurements Compared With Diffusion-Weighted Imaging in Anterior Circulation Stroke Clinical Sciences
Conclusions— The poor contrast:noise ratios of CT-CBV and CT-CBF compared with those of DWI result in large measurement error, making it problematic to substitute CTP for DWI in selecting individual acute stroke patients for treatment. CTP could be used for treatment studies of patient groups, but the number of patients needed to identify a significant effect is much higher than the number needed if DWI is used.
Source: Stroke - January 26, 2015 Category: Neurology Authors: Schaefer, P. W., Souza, L., Kamalian, S., Hirsch, J. A., Yoo, A. J., Kamalian, S., Gonzalez, R. G., Lev, M. H. Tags: CT and MRI, Acute Cerebral Infarction Clinical Sciences Source Type: research

Interhospital variation in reperfusion rates following endovascular treatment for acute ischemic stroke
Conclusions Reperfusion rates vary among hospitals, which may be related to differences in treatment protocols and patient characteristics. Additional studies are needed to identify all of the factors that underlie this variability as this could lead to strategies that reduce interhospital variability in reperfusion rates and improve clinical outcomes.
Source: Journal of NeuroInterventional Surgery - March 12, 2015 Category: Neurosurgery Authors: Liggins, J. T. P., Mlynash, M., Jovin, T. G., Straka, M., Kemp, S., Bammer, R., Marks, M. P., Albers, G. W., Lansberg, M. G., on behalf of the DEFUSE 2 Investigators Tags: Ischemic stroke Source Type: research

Human Urinary Kallidinogenase Improves Outcome of Stroke Patients by Shortening Mean Transit Time of Perfusion Magnetic Resonance Imaging
Improving cerebral perfusion remains a good option for ischemic stroke for restoring cerebral blood flow. Human urinary kallidinogenase has been shown promising in treating stroke patients. To investigate whether human urinary kallidinogenase's efficacy in treating stroke patients has relationship with improving cerebral perfusion and possible mechanism.
Source: Journal of Stroke and Cerebrovascular Diseases - June 29, 2015 Category: Neurology Authors: Jingwei Li, Yan Chen, Xin Zhang, Bing Zhang, Meijuan Zhang, Yun Xu Source Type: research

Computed Tomography Perfusion in Acute Ischemic Stroke: Is It Ready for Prime Time? Controversies in Stroke
Source: Stroke - July 27, 2015 Category: Neurology Authors: Liebeskind, D. S., Parsons, M. W., Wintermark, M., Selim, M., Molina, C. A., Lev, M. H., Gonzalez, R. G. Tags: Pathophysiology, Brain Circulation and Metabolism, Computerized tomography and Magnetic Resonance Imaging, Other Stroke Treatment - Surgical Controversies in Stroke Source Type: research

Thrombolysis, Complete Recanalization, Diffusion Reversal, and Luxury Perfusion in Hyperacute Stroke
A 59-year old man was admitted to our stroke care unit 1.8 hours after onset of cardioembolic stroke. Administration of issue-plasminogen activator achieved complete recanalization, and his lesion on diffusion-weighted imaging (DWI) disappeared and single photon emission computed tomography showed luxury perfusion. DWI reversal and luxury perfusion were sometimes observed in hyperacute stroke patients, especially timely reperfusion was achieved. However, the relationships between DWI reversal and luxury perfusion were not well known.
Source: Journal of Stroke and Cerebrovascular Diseases - October 28, 2015 Category: Neurology Authors: Yuki Sakamoto, Takahiro Ouchi, Seiji Okubo, Arata Abe, Junya Aoki, Akane Nogami, Takahiro Sato, Hiroyuki Hokama, Yutaro Ogawa, Shizuka Suzuki, Masahiro Mishina, Kazumi Kimura Tags: Case Report Source Type: research

Reperfusion Beyond 6 Hours Reduces Infarct Probability in Moderately Ischemic Brain Tissue Clinical Sciences
Conclusions— Brain tissue with mild to moderate ischemia can be salvaged by reperfusion even after 6 hours. Such tissue could be targeted for intervention beyond current treatment windows.
Source: Stroke - December 28, 2015 Category: Neurology Authors: An, H., Ford, A. L., Eldeniz, C., Chen, Y., Vo, K. D., Zhu, H., Powers, W. J., Lin, W., Lee, J.-M. Tags: Computerized Tomography (CT), Magnetic Resonance Imaging (MRI), Treatment, Ischemic Stroke Clinical Sciences Source Type: research

Clinical and Procedural Predictors of Outcomes From the Endovascular Treatment of Posterior Circulation Strokes Clinical Sciences
Conclusions— Time to the start of the procedure is an important predictor of clinical success after thrombectomy in patients with posterior circulation strokes. Both stent retriever and aspiration thrombectomy as primary treatment approaches are effective in achieving successful recanalization.
Source: Stroke - February 22, 2016 Category: Neurology Authors: Mokin, M., Sonig, A., Sivakanthan, S., Ren, Z., Elijovich, L., Arthur, A., Goyal, N., Kan, P., Duckworth, E., Veznedaroglu, E., Binning, M. J., Liebman, K. M., Rao, V., Turner, R. D., Turk, A. S., Baxter, B. W., Dabus, G., Linfante, I., Snyder, K. V., Lev Tags: Cerebrovascular Disease/Stroke, Cerebrovascular Procedures Clinical Sciences Source Type: research

Collateral Changes in Various MR Sequences and Their Clinical Implcation in Acute Stroke Patients (P6.024)
CONCLUSION: FHVS and PCA laterality is arterial while SWIHV is venous component of collateral circulation. Patients with these MR changes have smaller stroke size. SWIHV was not seen within large strokes.Disclosure: Dr. Ibrahim has nothing to disclose. Dr. Kamran has nothing to disclose. Dr. SATTAR has nothing to disclose. Dr. Akhtar has nothing to disclose. Dr. Elkhider has nothing to disclose. Dr. BOURKE has nothing to disclose. Dr. Shuaib has received research support from Pharma R11; AstraZeneca, CoAxia, Pfizer, BI, Sanofi, Servier, Merck Frosst, Bayer, NTI, Allphase, BMS, and Aventis.
Source: Neurology - April 3, 2016 Category: Neurology Authors: Ibrahim, F., Kamran, S., Sattar, H., Akhtar, N., Elkhider, H., Bourke, P., Shuaib, A. Tags: Ischemic Stroke Diagnosis Source Type: research