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Condition: Pain
Drug: Botox

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Total 28 results found since Jan 2013.

Evidence for therapeutic interventions for hemiplegic shoulder pain during the chronic stage of stroke: a review.
CONCLUSIONS: Positive outcomes were noted with the use of corticosteroid injections and electrical stimulation and conflicting results were seen regarding the use of BTx-A. Overall, these targeted therapies provide benefit in the treatment of HSP in individuals who are more than 6 months post stroke. PMID: 23192716 [PubMed - indexed for MEDLINE]
Source: Topics in Stroke Rehabilitation - November 1, 2012 Category: Neurology Authors: Viana R, Pereira S, Mehta S, Miller T, Teasell R Tags: Top Stroke Rehabil Source Type: research

Analysis of a 15-years' experience in including shoulder muscles, when treating upper-limb spasticity post-stroke with botulinum toxin type A.
Conclusion When treating ULS, including shoulder muscles, the most frequent goals were IM, PD e MOB. The most injected muscles were SC and PM. The treatment was successful in a large percentage of cases. Achieving the PD goal was associated with greater success at other goals of treatment. BoNTA demonstrated a positive effect in controlling symptoms and improving function. PMID: 29322885 [PubMed - as supplied by publisher]
Source: Topics in Stroke Rehabilitation - January 11, 2018 Category: Neurology Authors: Carvalho MP, Pinto D, Gorayeb M, Jacinto J Tags: Top Stroke Rehabil Source Type: research

Assessing the efficacy of different upper limb hemiparesis interventions on improving health-related quality of life in stroke patients: a systematic review.
CONCLUSION: The review demonstrates the need for upper limb intervention studies to focus on QOL as a primary outcome measure in addition to the functional outcomes currently used. PMID: 23611858 [PubMed - in process]
Source: Topics in Stroke Rehabilitation - March 1, 2013 Category: Neurology Authors: Pulman J, Buckley E Tags: Top Stroke Rehabil Source Type: research

Early versus late injections of Botulinumtoxin type A in post-stroke spastic movement disorder: A literature review
Toxicon. 2023 May 3:107150. doi: 10.1016/j.toxicon.2023.107150. Online ahead of print.ABSTRACTPost-stroke spastic movement disorder (PS-SMD) is one of the main causes of severe disability in the chronic phase after stroke. The prevalence of SMD rises up with time after stroke to more than 28% in the chronic phase, and its secondary complications such as contracture, abnormal postures and/or movement patterns, spasticity-associated pain, also increases with time after stroke when physical and medical management of PS-SMD had been delayed in the early stroke phase. It has been published by several controlled studies that the...
Source: Toxicon - May 5, 2023 Category: Toxicology Authors: J örg Wissel Songjin Ri Anatol Kivi Source Type: research

Botuloscope: 1-year follow-up of upper-limb post-stroke spasticity treated with botulinum toxin
Conclusion. This is the first long-term follow-up of BoNT-A treatment for upper-limb spasticity involving a large cohort independent of industry. Quality of life was improved by treating upper-limb spasticity with BoNT-A, even at 5 years post-stroke. Personalizing objectives of the treatment amplified its efficacy. BoNT-A was a powerful analgesic when pain was spasticity-related. Treating the spastic upper limb also improved balance and gait abilities.
Source: Annals of Physical and Rehabilitation Medicine - June 22, 2019 Category: Rehabilitation Source Type: research

Botuloscope: 1-year follow-up of upper limb post-stroke spasticity treated with botulinum toxin
ConclusionThis is the first long-term follow-up of BoNT-A treatment for upper limb spasticity involving a large cohort independent of industry. Quality of life was improved by treating upper limb spasticity with BoNT-A, even at 5 years post-stroke. Personalizing objectives of the treatment amplified its efficacy. BoNT-A was a powerful analgesic when pain was spasticity-related. Treating the spastic upper limb also improved balance and gait abilities.
Source: Annals of Physical and Rehabilitation Medicine - June 25, 2019 Category: Rehabilitation Source Type: research

Efficacy and safety of botulinum toxin type A (Dysport) for the treatment of post-stroke arm spasticity: Results of the German–Austrian open-label post-marketing surveillance prospective study
Abstract: The current practice in Germany and Austria, and the safety and efficacy of botulinum toxin type A (BoNT-A; Dysport) in the treatment of patients with post-stroke arm spasticity (with no fixed upper-limb contractures), were assessed in this observational prospective non-interventional study. One treatment cycle was documented with assessments at baseline, approximately week 4 (optional), and approximately week 12. Pattern of spasticity, treatment goal, safety and efficacy were recorded. Overall response and goal achievement was rated on a 4-point scale (‘no goal achievement’, ‘goal achievement’, ‘good g...
Source: Journal of the Neurological Sciences - December 23, 2013 Category: Neurology Authors: Wolfgang H. Jost, Harald Hefter, Andrea Reissig, Katja Kollewe, Joerg Wissel Tags: Original Articles Source Type: research

SBOTE Study: Extracorporeal Shock Wave Therapy Versus Electrical Stimulation After Botulinum Toxin Type A Injection for Post-Stroke Spasticity–A Prospective Randomized Trial
Abstract: Research is on-going to identify new methods of biostimulation to increase the effect of botulinum toxin type A (BTX-A) in the treatment of spasticity. The Spasticity treated by Botulinum Toxin and ESWT (SBOTE) study is a prospective, randomized controlled trial assessing the effectiveness of extracorporeal shock wave therapy (ESWT) given immediately after BTX-A injections compared with electrical stimulation (ES) given immediately after BTX-A therapy for the management of focal upper limb spasticity in stroke patients. ES was given for 30 min twice a day for 5 days starting at 5 Hz; ESWT was given once a day for...
Source: Ultrasound in Medicine and Biology - December 17, 2012 Category: Radiology Authors: Andrea Santamato, Angela Notarnicola, Francesco Panza, Maurizio Ranieri, Maria Francesca Micello, Paolo Manganotti, Biagio Moretti, Francesca Fortunato, Serena Filoni, Pietro Fiore Tags: Original Contributions Source Type: research

Effect of Ultrasound-Guided Injection Of Botulinum Toxin Type A for Shoulder Pain On Post-Stroke Patients
To study the effect of ultrasound-guided injection of botulinum toxin type A for shoulder pain on patients with stroke.
Source: Archives of Physical Medicine and Rehabilitation - September 24, 2017 Category: Rehabilitation Authors: Xiao Bao, Howe Liu, Hao Liu, Jiewen Tan, Ying Long, Myles Quiben Source Type: research

Pain and muscles properties modifications after botulinum toxin type A (BTX-A) and radial Extracorporeal Shock Wave (rESWT) combined treatment.
CONCLUSIONS: Radial Extracorporeal Shock Wave Therapy could be an effective physical treatment aimed at the reduction of upper and lower limbs spasticity and could lead to the improvement of trophic conditions of the spastic muscles in post-stroke. PMID: 30843498 [PubMed - as supplied by publisher]
Source: Endocrine, Metabolic and Immune Disorders Drug Targets - March 8, 2019 Category: Drugs & Pharmacology Tags: Endocr Metab Immune Disord Drug Targets Source Type: research

Clinical efficacy of botulinum toxin type A in patients with traumatic brain injury, spinal cord injury, or multiple sclerosis: An observational longitudinal study
This study aims to clarify the role of BoNT-A in the context of non-stroke spasticity (NSS). We enrolled 86 patients affected by multiple sclerosis, spinal cord injury, and traumatic brain injury with clinical indication to perform BoNT-A treatment. Subjects were evaluated before injection and after 1, 3, and 6 months. At every visit, spasticity severity using the modified Ashworth scale, pain using the numeric rating scale, QoL using the Euro Qol Group EQ-5D-5L, and the perceived treatment effect using the Global Assessment of Efficacy scale were recorded. In our population BoNT-A demonstrated to have a significant effect...
Source: Frontiers in Neurology - April 6, 2023 Category: Neurology Source Type: research

Top medicine articles for April 2014
A collection of some interesting medical articles published recently:A Big Bet on Gluten-Free: 11% of households reporting purchases of gluten-free foods in 2013 (doubled in 3 yrs). 30% of the public says it would like to cut back on the amount of gluten it’s eating. "There is a growing population of people who have somehow heard that gluten-free is healthier or think of it as fashionable, and when they remove gluten from their diet, they’re inadvertently taking out a lot of processed foods and are really feeling the benefits of eating healthier foods.” http://buff.ly/1mt9phmNew nomenclature and classifications are p...
Source: Clinical Cases and Images - April 23, 2014 Category: Journals (General) Tags: Health News of the Day Source Type: news

A survey of the current practice of intramuscular Botulinum toxin injections for hemiplegic shoulder pain in the UK.
CONCLUSIONS: Current UK practice of Botulinum Toxin type A injections for hemiplegic shoulder pain associated with spasticity is highly variable. There are large gaps between current practice and available evidence with regards to muscle selection and doses used. A number of areas for further investigation have been identified to progress current understanding of this intervention. Implications for rehabilitation There are wide variations in practice for this complex intervention and clinicians should consider that their individual decision-making could be based on their own beliefs rather than available evidence. Pectoral...
Source: Disability and Rehabilitation - November 10, 2017 Category: Rehabilitation Authors: Holmes RJ, Connell LA Tags: Disabil Rehabil Source Type: research

Clinical effectiveness of ultrasound guided subacromial-subdeltoid bursa injection of botulinum toxin type A in hemiplegic shoulder pain: A retrospective cohort study
Hemiplegic shoulder pain (HSP), which occurs in most patients with hemiplegia, causes considerable distress and worsens outcomes in rehabilitation. Although they have received the treatments such as anti-inflammatory drugs or physical therapy, many of the individuals remain suffering from shoulder pain 6 months after acute stroke event. In this retrospective study, we evaluated the effectiveness of ultrasound guided subacromial-subdeltoid (SASD) bursa injections with botulinum toxin type A (BoNT/A) compared to steroids for refractory HSP. The data were collected retrospectively by reviewing the patient's medical records a...
Source: Medicine - November 1, 2019 Category: Internal Medicine Tags: Research Article: Observational Study Source Type: research