Botuloscope: 1-year follow-up of upper limb post-stroke spasticity treated with botulinum toxin

Publication date: Available online 20 June 2019Source: Annals of Physical and Rehabilitation MedicineAuthor(s): Philippe Marque, Angelique Denis, David Gasq, Emmanuelle Chaleat-Valayer, Alain Yelnik, Cyrille Colin, Botuloscope Group, Dominic PérennouAbstractBackgroundBotuloscope is a cohort study supported by a French public grant and aiming to evaluate a 1-year treatment of the post-stroke spastic upper limb with botulinum toxin type A (BoNT-A) in terms of individual satisfaction with respect to personalized goals and quality of life.MethodsThis was an open-label prospective, multicentric study (11 French centres) that followed 330 adults [mean (SD) age 53.7 (13.7) years] over 1 year; participants had ranked 5 therapeutic goals at inclusion [mean (SD) 5.1 (7.3) years post-stroke], had severe hemiparesis [median motricity index (MI) 40 (Q1–Q3 24 to 60)], and were assessed at inclusion (M0) and at month 3 (M3) and M12. Outcome criteria were: spasticity, range of motion, pain [visual analog scale (VAS)], motor function [Modified Ashworth Scale (MAS)] and activities (MI; Frenchay Arm Test), and overall satisfaction with the achievement of each goal (VAS) and quality of life (Reintegration to Normal Life Index). Criteria at M0 and M12 were compared. Adverse effects were also collected, as were medication changes.ResultsThe primary goal was comfort and activities for 63% of participants and motor function for 36%. Participants underwent a mean of 2.4 injection session...
Source: Annals of Physical and Rehabilitation Medicine - Category: Rehabilitation Source Type: research

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