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Condition: Diabetic Ulcers

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Total 231 results found since Jan 2013.

First patient receives innovative new treatment to tackle combined diabetes and obesity in NHS approved trial initiated by the ABCD, UK
Combined diabetes and obesity, 'diabesity', is a serious health problem with considerably increased risks of premature heart attack, stroke and death. If not controlled, it can also affect the eyes leading to blindness, the kidneys leading to kidney failure and the feet leading to ulcers and amputation. The number of patients with diabesity is increasing rapidly, both in the UK and world-wide...
Source: Health News from Medical News Today - July 26, 2013 Category: Consumer Health News Tags: Diabetes Source Type: news

Taking over the counter pain relievers safely
For aching joints or a throbbing head, millions of Americans turn to aspirin, ibuprofen (Advil, Motrin), or other nonsteroidal anti-inflammatory drugs (NSAIDs) every day. They are generally safe, but if not used carefully NSAIDs can have a dark side, according to the September 2013 Harvard Women's Health Watch. NSAIDs are widely used because they perform double duty. “They not only relieve pain, but they reduce inflammation too,” says Dr. Lucy Chen, an assistant professor at Harvard Medical School and attending physician in the anesthesia, critical care, and pain medicine department at Massachusetts General Hos...
Source: New Harvard Health Information - August 23, 2013 Category: Consumer Health News Source Type: news

The association between self-reported history of physical diseases and psychological distress in a community-dwelling Japanese population: the Ohsaki Cohort 2006 Study
Conclusions: Subjects with a history of physical disease were significantly and positively associated with psychological distress, and social support did not modify this association for most physical diseases. Even after patients have left hospital following treatment for physical disease, they require continuous monitoring for psychological distress by doctors and paramedics.
Source: The European Journal of Public Health - January 24, 2014 Category: Journals (General) Authors: Nakaya, N., Kogure, M., Saito-Nakaya, K., Tomata, Y., Sone, T., Kakizaki, M., Tsuji, I. Tags: Mental health Source Type: research

Metabolic consequences of Helicobacter pylori infection and eradication.
Abstract Helicobacter pylori (H. pylori) is still the most prevalent infection of the world. Colonization of the stomach by this agent will invariably induce chronic gastritis which is a low-grade inflammatory state leading to local complications (peptic ulcer, gastric cancer, lymphoma) and remote manifestations. While H. pylori does not enter circulation, these extragastric manifestations are probably mediated by the cytokines and acute phase proteins produced by the inflammed mucosa. The epidemiologic link between the H. pylori infection and metabolic changes is inconstant and controversial. Growth delay was des...
Source: World Journal of Gastroenterology : WJG - May 14, 2014 Category: Gastroenterology Authors: Buzás GM Tags: World J Gastroenterol Source Type: research

Peripheral Arterial Disease Screening Within a Hispanic Community
Peripheral arterial disease (PAD) affects 8-12 million Americans annually. By 2050, PAD is estimated to affect 9.6-16 million Americans over age 65. PAD develops when the arteries supplying blood to the extremities become narrowed, largely due to atherosclerosis. Typically PAD refers to diseases of the arteries in the legs which are plagued by fatty deposits that progress and result in varying degrees of stenosis. With decreased blood flow to the leg muscles, individuals with PAD experience a cramp or ache which causes them to stop and rest. As PAD advances, infections and ulcers may develop. Additionally, individuals wit...
Source: Journal of Vascular Nursing - June 1, 2014 Category: Nursing Authors: Kathleen M. Large, M. Eileen Walsh Tags: 2014 SVN National Conference Poster Abstracts Source Type: research

Agent Orange exposure and disease prevalence in Korean Vietnam veterans: The Korean veterans health study.
In conclusion, Agent Orange exposure increased the prevalence of endocrine disorders, especially in the thyroid and pituitary gland; various neurologic diseases; COPD; and liver cirrhosis. Overall, this study suggests that Agent Orange/2,4-D/TCDD exposure several decades earlier may increase morbidity from various diseases, some of which have rarely been explored in previous epidemiologic studies. PMID: 24906069 [PubMed - as supplied by publisher]
Source: Environmental Research - June 3, 2014 Category: Environmental Health Authors: Yi SW, Hong JS, Ohrr H, Yi JJ Tags: Environ Res Source Type: research

Prevalence of diabetic foot disorders and related risk factors among Egyptian subjects with diabetes.
CONCLUSION: In Egypt, a mosaic of risk factors contributes to the high prevalence of diabetic foot disease in type 2 diabetes. These findings call for regular assessment of vascular, neuropathic and skin status to prevent these serious foot complications. PMID: 25543864 [PubMed - as supplied by publisher]
Source: Primary Care - December 17, 2014 Category: Primary Care Authors: Assaad-Khalil SH, Zaki A, Rehim AA, Megallaa MH, Gaber N, Gamal H, Rohoma KH Tags: Prim Care Diabetes Source Type: research

Population norms for the EQ-5D index scores using Singapore preference weights
Conclusions These findings support the use of the Singapore preference weights for EQ-5D valuations when measuring health-related quality of life and comparing the health burden of psychiatric and chronic physical conditions among adults in Singapore.
Source: Quality of Life Research - June 1, 2015 Category: Health Management Source Type: research

Preventing amputation in adults with diabetes: identifying the risks.
Abstract Good management of diabetes can reduce the risk of complications of the disease. When not well managed, diabetes is associated with the complications of heart disease, stroke, blindness, kidney disease and amputations. Diabetes can reduce the blood supply to the feet and cause a loss of feeling. As a result, foot injuries do not heal well and the person may not realise that their foot is sore or injured. Damage to the foot may lead to the development of foot ulcers, which if left untreated may result in amputation of the limb. Preventive care is a priority, but when complications occur the next step is to...
Source: Nursing Standard - June 3, 2015 Category: Nursing Authors: Thomas E Tags: Nurs Stand Source Type: research

Glucose stimulates chondrocyte differentiation of vascular smooth muscle cells and calcification: a possible role for IL-1β
Medial arterial calcification is a feature of diabetic individuals. In 4,553 subjects examined in a 20- year longitudinal study, calcification was shown to first appear in the feet and develop proximally [1]. It is believed to be an independent predictor of cardiovascular abnormalities in diabetic patients and is associated with trophic foot ulceration and peripheral artery occlusive disease [2–4]. For instance, in a study of 1,059 patients with type 2 diabetes mellitus (T2DM), vascular calcification, especially in the media, was found to be a strong independent predictor of total cardiovascular and coronary heart diseas...
Source: FEBS Letters - August 12, 2015 Category: Biochemistry Authors: Laurence Bessueille, Maya Fakhry, Eva Hamade, Bassam Badran, David Magne Source Type: research

Chronic disease and lifestyle factors associated with change in sleep duration among older adults in the Singapore Chinese Health Study
This study aimed to identify factors associated with change in sleep duration in a large sample of older adults (≥ 60 years) residing in Singapore (n = 10 335). These adults were monitored as part of the Singapore Chinese Health Study, which collected information regarding daily sleep duration at baseline (assessed in 1993–1998) and at a follow‐up wave conducted over a mean of 12.7 years later (assessed in 2006–2010). Among adults sleeping 6–8 h at baseline (n = 8265), most participants (55.6%) remained 6–8 h sleepers at follow‐up, while 8.4% became short (< 6 h) and 36.0% became long (> 8...
Source: Journal of Sleep Research - September 28, 2015 Category: Neurology Authors: Stephen F. Smagula, Woon‐Puay Koh, Renwei Wang, Jian‐Min Yuan Tags: Regular Research Paper Source Type: research

Prescription patterns of traditional Chinese medicine for peptic ulcer disease in Taiwan: A nationwide population-based study
Conclusions Our study identified the core prescription patterns of TCM for patients with peptic ulcer disease in Taiwan. Further basic and clinical studies are necessary to elucidate the efficacy and mechanisms. Graphical abstract
Source: Journal of Ethnopharmacology - November 18, 2015 Category: Drugs & Pharmacology Source Type: research

Outcomes of Chopart Amputation in a Tertiary Referral Diabetic Foot Clinic: Data From a Consecutive Series of 83 Hospitalized Patients
The purpose of the present retrospective study was to evaluate the outcomes (ie, ulcer recurrence, major amputation, death) in diabetic patients undergoing Chopart amputation because of deep infection or gangrene extending to the midfoot. From 2009 to 2011, 83 patients, aged 71.4 ± 9.3 years, underwent a midtarsal amputation and were followed up until December 31, 2012 (mean follow-up 2.8 ± 0.8 years). Of the 83 patients, 26 were female, 61 required insulin, 47 had renal insufficiency, 19 underwent hemodialysis, 65 had hypertension, 34 had a history of cardiac disease, and 4 had a history of stroke.
Source: Journal of Foot and Ankle Surgery - November 24, 2015 Category: Orthopaedics Authors: Ezio Faglia, Giacomo Clerici, Robert Frykberg, Maurizio Caminiti, Vincenzo Curci, Francesco Cetta, Vincenzo Prisco, Rosaria Greco, Marco Prisco, Alberto Morabito Tags: Original Research Source Type: research

The association between participation in a pay-for-performance program and macrovascular complications in patients with type 2 diabetes in Taiwan: A nationwide population-based cohort study
Conclusions Compared with patients not enrolled in the P4P program, P4P patients had lower risk of developing serious vascular complications. Our empirical findings provide evidence for the potential long-term benefit of P4P programs in reducing risks of macrovascular complications.
Source: Preventive Medicine - January 11, 2016 Category: Global & Universal Source Type: research

Cardiovascular Comorbidities Relate More than Others with Disease Activity in Rheumatoid Arthritis
Conclusions Cardiovascular comorbidities relate more than others with disease activity in RA. Diabetes and hyperlipidemia in particular seem associated with higher and lower disease activity respectively influencing almost all considered outcomes, suggesting a special importance of this pattern of comorbidities in disease activity assessment and clinical management.
Source: PLoS One - January 12, 2016 Category: Biomedical Science Authors: Gloria Crepaldi et al. Source Type: research