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The Racial Gap in U.S. Stroke Deaths Got Worse During the Pandemic
NEW YORK — The longstanding racial gap in U.S. stroke death rates widened dramatically during the COVID-19 pandemic, government researchers said Thursday. Stroke death rates increased for both Black and white adults in 2020 and 2021, according to the Centers for Disease Control and Prevention study. But the difference between the two groups grew about 22%, compared with the five years before the pandemic. “Any health inequity that existed before seems to have been made larger during the pandemic,” said Dr. Bart Demaerschalk, a stroke researcher at the Mayo Clinic in Phoenix who was not involved in the new...
Source: TIME: Health - April 20, 2023 Category: Consumer Health News Authors: Mike Stobbe/AP Tags: Uncategorized COVID-19 healthscienceclimate Source Type: news

Knowledge, health‐promoting behaviors, and biological risks of recurrent stroke among stroke patients in Korea
ConclusionStroke patients exhibited appropriate stroke knowledge and performed moderate to high levels of health‐promoting behaviors. However, 73.2% of patients had uncontrolled risk factor(s) in one or more of the five biological risk factors for stroke recurrence. Nurses should be aware that stroke patients seeking treatments from clinics and hospitals are still at risk of stroke recurrence.
Source: Japan Journal of Nursing Science - March 26, 2013 Category: Nursing Authors: Hei Ryun Lee, Ok Kyung Ham, Young Whee Lee, Insook Cho, Hyun Soo Oh, Joung‐Ho Rha Tags: Original Article Source Type: research

Reduction in Early Stroke Risk in Carotid Stenosis With Transient Ischemic Attack Associated With Statin Treatment
In patients with acute symptomatic carotid stenosis, statin pretreatment is associated with reduced stroke risk. Carotid endarterectomy (CEA) in patients with associated symptoms is highly effective for secondary stroke prevention. Maximum benefit appears to be in those who undergo surgery ≤2 weeks of symptom onset; however, the safety of very early CEA has been questioned. Data from the Swedish Vascular Registry indicated an 11.5% stroke and death rate in patients undergoing CEA ≤48 hours of symptom onset. This is a fourfold increase in the odds of a poor outcome compared with those undergoing CEA from 3 to 7 days (S...
Source: Journal of Vascular Surgery - January 24, 2014 Category: Surgery Authors: Á. Merwick, G.W. Albers, E.M. Arsava Tags: Abstracts Source Type: research

Stroke Literacy in Singapore: Data From a Survey of Public Housing Estate Residents.
Conclusion: In a sample of Singaporean adults residing in a public housing estate, we found evidence of poor stroke literacy, highlighting the need for comprehensive population-based education efforts. There is a role for opportunistic education among those at higher risk of stroke. PMID: 25341630 [PubMed - as supplied by publisher]
Source: Annals of the Academy of Medicine, Singapore - September 1, 2014 Category: Journals (General) Authors: Lim W, Chuang DF, Chue KM, Lee DZ, Leong NJ, Ng ZG, Peng K, Shen X, Tham YN, Wang K, De Silva DA Tags: Ann Acad Med Singapore Source Type: research

Statins in stroke prevention: present and future.
CONCLUSION: Traditionally, there has been no clear data demonstrating that adding other lipid-modifying drugs to statins results in a further decrease in stroke or other cardiovascular event, but now things have changed and future directions include combinations with ezetimibe and new treatments such as PCSK9 inhibitors. Only time will tell the real roll of these new promising non-statin lipid-modifying therapies on stroke prevention. PMID: 27160755 [PubMed - as supplied by publisher]
Source: Current Pharmaceutical Design - May 9, 2016 Category: Drugs & Pharmacology Authors: Castilla-Guerra L, Del Carmen Fernandez-Moreno M, Colmenero-Camacho MA Tags: Curr Pharm Des Source Type: research

Global burden of stroke and risk factors in 188 countries, during 1990–2013: a systematic analysis for the Global Burden of Disease Study 2013
Publication date: Available online 9 June 2016 Source:The Lancet Neurology Author(s): Valery L Feigin, Gregory A Roth, Mohsen Naghavi, Priya Parmar, Rita Krishnamurthi, Sumeet Chugh, George A Mensah, Bo Norrving, Ivy Shiue, Marie Ng, Kara Estep, Kelly Cercy, Christopher J L Murray, Mohammad H Forouzanfar Background The contribution of modifiable risk factors to the increasing global and regional burden of stroke is unclear, but knowledge about this contribution is crucial for informing stroke prevention strategies. We used data from the Global Burden of Disease Study 2013 (GBD 2013) to estimate the populati...
Source: The Lancet Neurology - June 9, 2016 Category: Neurology Source Type: research

Global burden of stroke and risk factors in 188 countries, during 1990 –2013: a systematic analysis for the Global Burden of Disease Study 2013
Publication date: August 2016 Source:The Lancet Neurology, Volume 15, Issue 9 Author(s): Valery L Feigin, Gregory A Roth, Mohsen Naghavi, Priya Parmar, Rita Krishnamurthi, Sumeet Chugh, George A Mensah, Bo Norrving, Ivy Shiue, Marie Ng, Kara Estep, Kelly Cercy, Christopher J L Murray, Mohammad H Forouzanfar Background The contribution of modifiable risk factors to the increasing global and regional burden of stroke is unclear, but knowledge about this contribution is crucial for informing stroke prevention strategies. We used data from the Global Burden of Disease Study 2013 (GBD 2013) to estimate the popul...
Source: The Lancet Neurology - July 20, 2016 Category: Neurology Source Type: research

Sex differences in outcomes after stroke among patients with low total cholesterol levels: a large hospital-based prospective study
ConclusionsThese findings suggest that patients (both men and women) with atherothrombotic infarction who have low TC levels would not benefit from receiving statin treatment. Therefore, it is crucial to explore the impact of statin treatment on outcomes in Asian patients, especially Chinese patients with atherothrombotic and low TC levels, in order to improve outcomes after stroke and reduce the disease burden.
Source: Biology of Sex Differences - November 23, 2016 Category: Biology Source Type: research

Transient ischemic attack and ischemic stroke patients with or without prior stroke
ConclusionsBoth in TIA and IS, vascular risk factors were more common in patients with a history of stroke compared with those without. In contrast to other secondary preventive medications, OAC treatment in the presence of AF was underutilized in patients with a history of stroke.
Source: Acta Neurologica Scandinavica - June 1, 2017 Category: Neurology Authors: F. Buchwald, B. Norrving, J. Petersson Tags: ORIGINAL ARTICLE Source Type: research

Anti-inflammatory treatment and risk for depression after first-time stroke in a cohort of 147 487 Danish patients.
CONCLUSION: Anti-inflammatory treatment is associated with a lower risk for depression shortly after stroke but a higher risk for late depression. This suggests that inflammation contributes differently to the development of depression after stroke depending on the time of onset. PMID: 28632121 [PubMed - as supplied by publisher]
Source: Journal of Psychiatry and Neuroscience - June 22, 2017 Category: Psychiatry Tags: J Psychiatry Neurosci Source Type: research

Stroke-Related Disease Comorbidity and Secondary Stroke Prevention Practices Among Young Stroke Survivors
Conclusions: Many young stroke survivors exhibit comorbid disease conditions that are similar to older stroke survivors. A large percentage are engaged in general chronic disease and secondary stroke prevention practices, yet less than two-thirds had seen a general doctor in the past 12 months. Primary care doctors and other health professionals are critical to the implementation of disease management strategies that consider their age, secondary stroke risk, expected life spans, and other issues that differ from older adult stroke survivors.
Source: Journal of Neuroscience Nursing - September 8, 2017 Category: Neuroscience Tags: Article Source Type: research

Suboptimal lipid management before and after ischaemic stroke and TIA —the North Dublin Population Stroke Study
ConclusionsIn this population-based study, LLT recommended by international guidelines was under-used, before and after index stroke/TIA. Strategies to improve adherence are needed.
Source: Irish Journal of Medical Science - January 24, 2018 Category: General Medicine Source Type: research

Relationship of Familial Hypercholesterolemia and High LDL Cholesterol to Ischemic Stroke: The Copenhagen General Population Study.
Conclusions -FH and high LDL cholesterol did not confer an increased risk of ischemic stroke. A positive association with ischemic stroke observed for some clinical FH criteria and high LDL cholesterol appears to be due by previous ischemic heart disease, rather than by high LDL cholesterol per se. PMID: 29593013 [PubMed - as supplied by publisher]
Source: Circulation - March 28, 2018 Category: Cardiology Authors: Beheshti S, Madsen CM, Varbo A, Benn M, Nordestgaard BG Tags: Circulation Source Type: research

Statin treatment before stroke reduces pro-inflammatory cytokine levels after stroke.
CONCLUSION: Stroke induces changes in the RhoA-ROCK pathway in T-cells. CRP and NIHSS score correlated positively in the study. Statins may have an anti-inflammatory effect as statin treatment before stroke reduces post-stroke pro-inflammatory levels. RhoA GTPase and its downstream effectors are possibly the key to improve statin treatment in stroke. PMID: 30574850 [PubMed - as supplied by publisher]
Source: Neurological Research - December 24, 2018 Category: Neurology Tags: Neurol Res Source Type: research

Egg consumption, cholesterol intake, and risk of incident stroke in men: the Kuopio Ischaemic Heart Disease Risk Factor Study.
CONCLUSION: Neither egg nor cholesterol intakes were associated with stroke risk in this cohort, regardless of apoE phenotype.This trial was registered at www.clinicaltrials.gov as NCT03221127. PMID: 31095282 [PubMed - as supplied by publisher]
Source: The American Journal of Clinical Nutrition - May 15, 2019 Category: Nutrition Authors: Abdollahi AM, Virtanen HEK, Voutilainen S, Kurl S, Tuomainen TP, Salonen JT, Virtanen JK Tags: Am J Clin Nutr Source Type: research