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Condition: Heatstroke

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Total 1318 results found since Jan 2013.

Emergency Department Visits for Heat Stroke in the United States, 2009 and 2010
Conclusions: Heat stroke results in approximately 4,100 ED visits each year in the United States, with the majority occurring in the summer months and requiring admission to the hospital. Men, the elderly, and people living in the south region are at heightened risk.
Source: Epidemiologic Perspectives and Innovations - April 24, 2014 Category: Epidemiology Authors: Xian WuJoanne E BradyHenry RosenbergGuohua Li Source Type: research

Stress-induced cardiomyopathy accompanied by heat stroke
We describe a case with high body temperature and coma, who also presented with wide QRS tachycardia and shock. He was initially treated for heat stroke and wide QRS tachycardia. Serial electrocardiographic change and echocardiographic findings suggested this was complicated with stress-induced cardiomyopathy. This case demonstrates the importance of recognizing that serious myocardial damage can result from heat stroke. <Learning objective: Heat stroke can cause multiple organ failure and the presentation of circulatory failure in heat stroke may be the sign of myocardial dysfunction. To distinguish acute coronary ...
Source: Journal of Cardiology Cases - May 2, 2015 Category: Cardiology Source Type: research

Current concepts in the management of exertional heat stroke in athletes
Exertional heat stroke is a severe heat illness involving the central nervous system and other organ systems induced by strenuous exercise, usually in hot and humid environments, associated with an elevation in core body temperature. By definition, exertional heat stroke is present when the core body temperature measured rectally exceeds 105 degrees F and central nervous system dysfunction is present. If recognized early and treated promptly, deaths from exertional heat stroke are completely preventable. Despite the well-described management option of cooling the body with ice water immersion, which is affordable and easy ...
Source: Current Orthopaedic Practice - May 1, 2015 Category: Orthopaedics Tags: Review Articles Source Type: research

Quercetin protects against heat stroke-induced myocardial injury in male rats: Antioxidative and antiinflammatory mechanisms.
Abstract Heat stroke is characterilized by hyperthermia, systemic inflammation, and multiple organ failure including arterial hypotension. This definition can be fulfilled by a rat model of heat stroke used in the present study. Anesthetized animals were exposed to heat exposure (43 °C for 70 min) and then returned to room temperature (26 °C) for recovery. One hour before heat exposure, an intraperitoneal dose of quercetin (30 mg/kg) or vehicle (normal saline 1 ml/kg) was administered to the experimental groups of rats. Additional injection was administered immediately after the onset of heat stroke. Immedi...
Source: Chemico-Biological Interactions - January 15, 2017 Category: Molecular Biology Authors: Lin X, Lin CH, Zhao T, Zuo D, Ye Z, Liu L, Lin MT Tags: Chem Biol Interact Source Type: research

Calcitonin gene-related peptide has protective effect on brain injury induced by heat stroke in rats.
Authors: Lu CX, Qiu T, Liu ZF, Su L, Cheng B Abstract Heat stroke often leads to multiple organ dysfunction syndrome (MODS) with a neurological morbidity of 30%. Current studies suggested that pathophysiological responses to heat stroke may be due to a systemic inflammatory response syndrome and a series of peptidergic nerve reactions. The mechanisms underlying the high neurological morbidity in heat stroke have remained largely elusive. In recent years, calcitonin gene-related peptide (CGRP) has been considered to have a positive role in central nervous system injury. The present study investigated the influence o...
Source: Experimental and Therapeutic Medicine - December 6, 2017 Category: General Medicine Tags: Exp Ther Med Source Type: research

Sensors, Vol. 18, Pages 4347: Data Analytics of a Wearable Device for Heat Stroke Detection
ao Chen When exercising in a high-temperature environment, heat stroke can cause great harm to the human body. However, runners may ignore important physiological warnings and are not usually aware that a heat stroke is occurring. To solve this problem, this study evaluates a runner’s risk of heat stroke injury by using a wearable heat stroke detection device (WHDD), which we developed previously. Furthermore, some filtering algorithms are designed to correct the physiological parameters acquired by the WHDD. To verify the effectiveness of the WHDD and investigate the features of these physiological param...
Source: Sensors - December 9, 2018 Category: Biotechnology Authors: Shih-Sung Lin Chien-Wu Lan Hao-Yen Hsu Sheng-Tao Chen Tags: Article Source Type: research

A photostable Si-rhodamine-based near-infrared fluorescent probe for monitoring lysosomal pH during heat stroke.
Abstract Heat stroke is a symptom of hyperthermia with a temperature of more than 40 °C, which usually leads to all kinds of physical discomfort and even death. It is necessary to study the mechanism of action of heat stroke on cells or organelles (such as cytotoxicity of heat) and the processes of cells or organelles during heat stroke. Recent studies have shown that there is a certain correlation between heat stroke and lysosome acidity. In order to clarify their relationship, Lyso-NIR-pH, a photostable Si-rhodamine-based near-infrared fluorescent probe, was developed for sensing pH changes in lysosomes durin...
Source: Analytica Chimica Acta - November 13, 2019 Category: Chemistry Authors: Mao GJ, Liang ZZ, Gao GQ, Wang YY, Guo XY, Su L, Zhang H, Ma QJ, Zhang G Tags: Anal Chim Acta Source Type: research

Myricetin against myocardial injury in rat heat stroke model.
CONCLUSIONS: Our results indicate that myricetin diminishes myocardial injury as well as lethality in heat stroke by up-regulating HSP-72 and show promise as a novel prevention therapeutic for heat stroke. PMID: 32371315 [PubMed - as supplied by publisher]
Source: Biomedicine and pharmacotherapy = Biomedecine and pharmacotherapie - April 30, 2020 Category: Drugs & Pharmacology Authors: Lin X, Lin CH, Liu R, Li C, Jiao S, Yi X, Walker MJ, Xu XM, Zhao T, Huang PC, Sun G Tags: Biomed Pharmacother Source Type: research

Superior antioxidant and anti-ischemic neuroprotective effects of cerebrolysin in heat stroke following intoxication of engineered metal Ag and Cu nanoparticles: A comparative biochemical and physiological study with other stroke therapies
Prog Brain Res. 2021;266:301-348. doi: 10.1016/bs.pbr.2021.06.014. Epub 2021 Oct 6.ABSTRACTMilitary personnel are often exposed to high environmental heat associated with industrial or ambient abundance of nanoparticles (NPs) affecting brain function. We have shown that engineered metal NPs Ag and Cu exacerbate hyperthermia induced brain pathology. Thus, exploration of novel drug therapy is needed for effective neuroprotection in heat stroke intoxicated with NPs. In this investigation neuroprotective effects of cerebrolysin, a balanced composition of several neurotrophic factors and active peptides fragments exhibiting pow...
Source: Brain Research - October 25, 2021 Category: Neurology Authors: Hari Shanker Sharma Dafin F Muresanu Asya Ozkizilcik Seaab Sahib Z Ryan Tian Jos é Vicente Lafuente Rudy J Castellani Ala Nozari Lianyuan Feng Anca D Buzoianu Preeti K Menon Ranjana Patnaik Lars Wiklund Aruna Sharma Source Type: research

Effects of Cooling Interventions with Different Target Temperatures on Heat Stroke Rats
CONCLUSION: The mechanisms of cooling intervention in alleviating heat stroke-induced damage were associated with the expression changes of p-Akt, Caspase-3, Bax and Bcl-2. The better effect of Tc+1°C might be associated with low expression of Bax.PMID:37284704 | PMC:PMC10239648 | DOI:10.2147/JIR.S408316
Source: Cell Research - June 7, 2023 Category: Cytology Authors: Changdong Wu Ping Wang Bin Wang Muyesai Nijiati Ming Hou Source Type: research

Recommended water immersion duration for the field treatment of exertional heat stroke when rectal temperature is unavailable
ConclusionThe reported immersion durations are effective for  >  90% of exertional heat stroke patients with pre-immersion Tre of 39.5 –42.8 °C. When available, real-time Tre monitoring is the standard of care to accurately diagnose and treat exertional heat stroke, avoiding adverse health outcomes associated with under- or over-cooling, and for implementing cool-first transport second exertional heat stroke policies.
Source: European Journal of Applied Physiology - August 8, 2023 Category: Physiology Source Type: research

Life-Threatening Events During Endurance Sports Is Heat Stroke More Prevalent Than Arrhythmic Death?
ConclusionsIn our cohort of athletes participating in endurance sports, for every serious cardiac adverse event, there were 10 serious events related to heat stroke. One of the heat stroke–related fatalities presented with unheralded cardiac arrest. Our results put in a different perspective the ongoing debate about the role of pre-participation electrocardiographic screening for the prevention of sudden death in athletes.
Source: Journal of the American College of Cardiology: Cardiovascular Interventions - July 28, 2014 Category: Cardiology Source Type: research

Clearance of serum solutes by hemofiltration in dogs with severe heat stroke
Background: We have previously reported that hemofiltration (HF) may be an effective additional means of treating heat stroke when rapid cooling is not effective. Methods: Dogs were assigned to a heat stroke (control) or heat stroke?+?hemofiltration (HF) group (n?=?8 each group). After heat stroke induction, dogs in the HF group received HF for 3?h. Serum concentrations of interleukin (IL)-10, tumor necrosis factor (TNF)-?, IL-6, blood urea nitrogen (BUN) and creatinine were measured at baseline and 1, 2, and 3?h after heat stroke. Clearance rates of solutes were determined 1, 2, and 3?h after the start of HF. Results: Ser...
Source: Scandinavian Journal of Trauma, Resuscitation and Emergency Medicine - August 22, 2014 Category: Emergency Medicine Authors: Guang-Ming ChenYu-Ying LanCheng-Feng WangHai-Xia ZhanWen-Rui WangJin-Hua ChenJian Chen Source Type: research