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Condition: Heart Failure
Procedure: Heart Valve Surgery

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Total 447 results found since Jan 2013.

Workup and Management of Native and Prosthetic Valve Endocarditis
AbstractInfective endocarditis (IE) is associated with significant serious adverse outcomes including death. IE usually presents with diverse clinical picture and syndromic diagnoses including heart failure, stroke, and peripheral embolization. Given variable, vague, and syndromic presentations, the diagnosis of IE may be delayed for days to weeks. Maintaining a high index of suspicion among clinicians is the key to early recognition of the disease and prompt initiation of antimicrobial therapy to prevent IE-associated mortality and morbidity. Blood culture and echocardiography remain essential tools in the diagnosis of in...
Source: Current Treatment Options in Cardiovascular Medicine - August 7, 2018 Category: Cardiology Source Type: research

Neutrophil to Lymphocyte Ratio Predicts Heart Failure Readmissions and Outcomes in Patients Undergoing Transcatheter Aortic Valve Replacement
ConclusionNLR predicts all-cause mortality, MACE, and HF hospitalization 1-year post-TAVR. NLR with TAVR risk score improved predictability for MACE. Further studies for prognostication utilizing NLR are warranted.
Source: Indian Heart Journal - August 18, 2018 Category: Cardiology Source Type: research

MicroRNA 199a Is Downregulated in Patients After Coronary Artery Bypass Graft Surgery and Is Associated with Increased Levels of Sirtuin 1 (SIRT 1) Protein and Major Adverse Cardiovascular Events at 3-Year Follow-Up.
CONCLUSIONS Altered expression of miR-199a in myocardial tissue was found to be associated with SIRT 1 upregulation in patients with CAD undergoing CABG and was associated with an increased MACCEs rate at mid-term follow-up. PMID: 30192743 [PubMed - in process]
Source: Medical Science Monitor - September 8, 2018 Category: Research Tags: Med Sci Monit Source Type: research

Trans-catheter paravalvular leak closure: a single-centre experience
ConclusionsPatients with PVL represent a high-risk patient cohort. Percutaneous PVL offers a safe alternative to surgical PVL repair and appears particularly effective in those patients who present primarily with HF.
Source: Irish Journal of Medical Science - September 12, 2018 Category: General Medicine Source Type: research

Red Cell Distribution Width as a Prognostic Marker in Patients Undergoing Valve Surgery.
CONCLUSIONS: An elevated RDW is associated with a worse outcome following valve surgery. The predictive ability of the RDW, when assessed by the area under the ROC curve, improved the predictive ability of the EuroSCORE II calculator. PMID: 30207123 [PubMed - in process]
Source: Journal of Heart Valve Disease - September 13, 2018 Category: Cardiology Tags: J Heart Valve Dis Source Type: research

Neutrophil-to-lymphocyte ratio predicts heart failure readmissions and outcomes in patients undergoing transcatheter aortic valve replacement
ConclusionNLR predicts all-cause mortality, MACE, and HF hospitalization 1 year after TAVR. NLR with TAVR risk score improved predictability for MACE. Further studies for prognostication using NLR are warranted.
Source: Indian Heart Journal - September 14, 2018 Category: Cardiology Source Type: research

Preoperative Venoarterial Extracorporeal Membrane Oxygenation Slashes Risk Score in Advanced Structural Heart Disease
ConclusionsECMO can be used as a bridge to heart valve or septal defect surgery in severely decompensated patients. Through recovery of end-organ function, ECMO may allow surgical correction of structural heart disease in patients considered inoperable or convert a salvage situation to an elective operation.
Source: The Annals of Thoracic Surgery - September 18, 2018 Category: Cardiovascular & Thoracic Surgery Source Type: research

Preoperative Venoarterial Extracorporeal Membrane Oxygenation Slashes Risk Score in Advanced Structural Heart Disease.
CONCLUSIONS: ECMO can be used as a bridge to heart valve or septal defect surgery in severely decompensated patients. Through recovery of end-organ function, ECMO may allow surgical correction of structural heart disease in patients considered inoperable or convert a salvage situation to an elective operation. PMID: 30236527 [PubMed - as supplied by publisher]
Source: The Annals of Thoracic Surgery - September 17, 2018 Category: Cardiovascular & Thoracic Surgery Authors: Watkins AC, Maassel NL, Ghoreishi M, Dawood MY, Pham SM, Kon ZN, Taylor BS, Griffith BP, Gammie JS Tags: Ann Thorac Surg Source Type: research

Mitral repair in symptom-free patients with normal ventricles: Becoming the new normal?
We have all been there. A young, vigorous woman referred to you with severe asymptomatic mitral regurgitation is in your office to discuss surgical repair. You proceed to describe the incision you are going to make somewhere on her chest; the 1% to 2% risk of bleeding, stroke, infection, heart failure, and death; the fact that she may end up with a prosthetic mitral valve requiring lifelong anticoagulation; and the fact that she is going to have to miss a month or more of her Pilates classes because the American College of Cardiology and American Heart Association Task Force on Practice Guidelines (ACC/AHA) says that it is...
Source: The Journal of Thoracic and Cardiovascular Surgery - September 5, 2018 Category: Cardiovascular & Thoracic Surgery Authors: David D. Yuh Tags: Editorial Commentary Source Type: research

Risk stratification and clinical outcomes after surgical pulmonary valve replacement
ConclusionPatients undergoing PVR at larger RV volumes had similar survival but more overall CAE. A larger study population with a longer follow-up will be required to determine if early PVR provides survival benefit in the long-term.
Source: American Heart Journal - October 4, 2018 Category: Cardiology Source Type: research

Workup and Management of Native and Prosthetic Valve Endocarditis
AbstractInfective endocarditis (IE) is associated with significant serious adverse outcomes including death. IE usually presents with diverse clinical picture and syndromic diagnoses including heart failure, stroke, and peripheral embolization. Given variable, vague, and syndromic presentations, the diagnosis of IE may be delayed for days to weeks. Maintaining a high index of suspicion among clinicians is the key to early recognition of the disease and prompt initiation of antimicrobial therapy to prevent IE-associated mortality and morbidity. Blood culture and echocardiography remain essential tools in the diagnosis of in...
Source: Current Treatment Options in Cardiovascular Medicine - August 7, 2018 Category: Cardiology Source Type: research

Trans-catheter paravalvular leak closure: a single-centre experience
ConclusionsPatients with PVL represent a high-risk patient cohort. Percutaneous PVL offers a safe alternative to surgical PVL repair and appears particularly effective in those patients who present primarily with HF.
Source: Irish Journal of Medical Science - September 12, 2018 Category: General Medicine Source Type: research

Clinical Outcomes of Mitral Valve Reoperations in the United States: An Analysis of the Society of Thoracic Surgeons National Database
ConclusionsDespite a high-risk patient profile, surgical outcomes of reoperative MVS were acceptable, particularly in elective cases with prior mitral valve surgery and without endocarditis.
Source: The Annals of Thoracic Surgery - October 24, 2018 Category: Cardiovascular & Thoracic Surgery Source Type: research

Clinical Outcomes of Mitral Valve Reoperations in the United States: An Analysis of the Society of Thoracic Surgeons National Database.
CONCLUSIONS: Despite a high-risk patient profile, surgical outcomes of reoperative MVS were acceptable, particularly in elective cases with prior mitral valve surgery and without endocarditis. PMID: 30365952 [PubMed - as supplied by publisher]
Source: The Annals of Thoracic Surgery - October 23, 2018 Category: Cardiovascular & Thoracic Surgery Authors: Kilic A, Acker MA, Gleason TG, Sultan I, Vemulapalli S, Thibault D, Ailawadi G, Badhwar V, Thourani V, Kilic A Tags: Ann Thorac Surg Source Type: research

Clinical Leaflet Thrombosis in Transcatheter and Surgical Bioprosthetic Aortic Valves by Four-Dimensional Computed Tomography
ConclusionsOne-third of patients with clinical or echocardiographic indications suggestive of leaflet thrombosis were found to have evidence of leaflet thrombosis using 4DCT. This allowed tailored anticoagulation therapy with resolution of the thrombus in most patients and avoiding unnecessary anticoagulation in the remaining two-thirds of patients.Visual Abstract
Source: The Annals of Thoracic Surgery - November 16, 2018 Category: Cardiovascular & Thoracic Surgery Source Type: research