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Condition: Heart Failure
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Total 35 results found since Jan 2013.

Cell-Based Therapies for Stroke: Promising Solution or Dead End? Mesenchymal Stem Cells and Comorbidities in Preclinical Stroke Research
Conclusion The high prevalence of comorbidities in patients with stroke indicates the need for therapies in preclinical studies that take into account these comorbidities in order to avoid failures in translation to the patient. Preclinical studies are beginning to evaluate the efficacy of MSC treatment in stroke associated with comorbidities, especially hypertension, for ischemic and hemorrhagic stroke. Regarding aging and diabetes, only ischemic stroke studies have been performed. For the moment, few studies have been performed and contradictory results are being reported. These contradictory results may be due to the u...
Source: Frontiers in Neurology - April 8, 2019 Category: Neurology Source Type: research

Cerebrolysin for acute ischaemic stroke.
CONCLUSIONS: Moderate-quality evidence indicates that Cerebrolysin probably has little or no beneficial effect on preventing all-cause death in acute ischaemic stroke, or on the total number of people with serious adverse events. Moderate-quality evidence also indicates a potential increase in non-fatal serious adverse events with Cerebrolysin use. PMID: 32662068 [PubMed - in process]
Source: Cochrane Database of Systematic Reviews - July 13, 2020 Category: General Medicine Authors: Ziganshina LE, Abakumova T, Hoyle CH Tags: Cochrane Database Syst Rev Source Type: research

Potential Applications of Remote Limb Ischemic Conditioning for Chronic Cerebral Circulation Insufficiency
Conclusion Due to its long-term and often invisible course, CCCI has received less attention than acute cerebral ischemic stroke. However, without appropriate intervention, CCCI may lead to a variety of adverse events. Because the pathophysiological changes associated with CCCI are complex, pharmacological research in this area has been disappointing. Recent research suggests that RLIC, which is less invasive and more well-tolerated than drug treatment, can activate endogenous protective mechanisms during CCCI. In the present report, we reviewed studies related to CCCI (Table 1), as well as those related to stroke and sta...
Source: Frontiers in Neurology - May 2, 2019 Category: Neurology Source Type: research

Association of Ambient Air Pollution with Depressive and Anxiety Symptoms in Older Adults: Results from the NSHAP Study
Conclusion: PM2.5 was associated with depressive and anxiety symptoms, with associations the strongest among individuals with lower SES or among those with certain health-related characteristics. Citation: Pun VC, Manjourides J, Suh H. 2017. Association of ambient air pollution with depressive and anxiety symptoms in older adults: results from the NSHAP study. Environ Health Perspect 125:342–348; http://dx.doi.org/10.1289/EHP494 Address correspondence to H. Suh, Department of Civil and Environmental Engineering, Tufts University, Medford, MA 02153 USA. Telephone: (617) 627-2941. Email: Helen.Suh@tufts.edu We acknowl...
Source: EHP Research - March 1, 2017 Category: Environmental Health Authors: Web Admin Tags: Research Articles March 2017 Source Type: research

A pattern of brain activity may link stress to heart attacks
Conclusion This intriguing study sets out a possible pathway by which the effects of stress on the brain could translate into inflammation in the blood vessels, and so raise the risks of cardiovascular disease. This would help to explain why people living in stressful situations, or with illnesses such as depression and anxiety, are more at risk of heart attacks and strokes. However, there are important limitations to the study which mean we should treat the findings with caution. The main study of 293 people was relatively small for a long-term study looking at cardiovascular disease, and only 22 people had a cardiovascul...
Source: NHS News Feed - January 12, 2017 Category: Consumer Health News Tags: Neurology Mental health Source Type: news

Missed Opportunities for Appropriate Anticoagulation Among Emergency Department Patients With Uncomplicated Atrial Fibrillation or Flutter
Conclusion: In this cohort of ED patients with uncomplicated atrial fibrillation or flutter who were discharged without cardiology involvement, many were not appropriately anticoagulated before ED arrival, and more than half of such patients did not appear to have corrective measures initiated by the emergency physician. This may represent a potential opportunity to improve patient care and outcomes.
Source: Annals of Emergency Medicine - May 28, 2013 Category: Emergency Medicine Authors: Frank X. Scheuermeyer, Grant Innes, Reza Pourvali, Chris Dewitt, Eric Grafstein, Claire Heslop, Jan MacPhee, John Ward, Brett Heilbron, Lorraine McGrath, Jim Christenson Tags: Cardiology Source Type: research

Long-Term Exposure to Road Traffic Noise and Nitrogen Dioxide and Risk of Heart Failure: A Cohort Study
Conclusions: Long-term exposure to NO2 and road traffic noise was associated with higher risk of heart failure, mainly among men, in both single- and two-pollutant models. High exposure to both pollutants was associated with highest risk. https://doi.org/10.1289/EHP1272 Received: 25 October 2016 Revised: 09 August 2017 Accepted: 09 August 2017 Published: 26 September 2017 Address correspondence to M. Sørensen. Diet, Genes and Environment, Danish Cancer Society, Strandboulevarden 49, 2100 Copenhagen, Denmark. Telephone: +45 35257626. Email: mettes@cancer.dk Supplemental Material is available online (https://doi.org/1...
Source: EHP Research - September 26, 2017 Category: Environmental Health Authors: Daniil Lyalko Tags: Research Source Type: research

Combination of Dexmedetomidine and Ketamine for Magnetic Resonance Imaging Sedation
Conclusions: The efficacy of DEX–KET sedation was comparable to that of midazolam for MRI examination. DEX–KET was related to shorter scan time and lower occurrence of complications compared to midazolam. Introduction Neurocritically ill patients often require brain magnetic resonance imaging (MRI) in addition to conventional neurological evaluations. Brain MRI can reveal structural lesions with a high sensitivity due to its excellent spatial resolution and enhanced soft tissue contrast (1–3). To acquire MRI images, patients' cooperation is imperative. However, keeping patients with ...
Source: Frontiers in Neurology - April 23, 2019 Category: Neurology Source Type: research

Harnessing the Four Elements for Mental Health
DiscussionAs detailed above, the “elements” in both a classical and a contemporary sense have effects on our mental health and are potentially modifiable aspects that can be harnessed as therapeutic interventions. The most robust interventional evidence currently available shows tentative support for several use of the elements via horticultural and nature-exposure therapy, green exercise/physical activity, sauna and heat therapy, balneotherapy, and breathing exercises. It should be noted that, in many cases, these interventions were not studied in definitive diagnosed psychiatric disorders and thus it is pre...
Source: Frontiers in Psychiatry - April 23, 2019 Category: Psychiatry Source Type: research

Age-Dependence of Flow Homeostasis in the Left Ventricle
Conclusions: In average, blood spends 1 to 3 beats inside the LV with very low shear stress rates. The apical region is the most prone to blood stasis, particularly in mid-aged adults. The washout of blood in the normal LV is age-dependent due to physiological changes in the degree of apical penetration of the filling waves. Introduction Cardioembolic stroke is a major source of mortality and disability worldwide and blood stasis one of its major determinants (Adams et al., 1986). Left ventricular (LV) function has evolved to maximize mechanical efficiency and ensure organ perfusion at a low cost of energy and fill...
Source: Frontiers in Physiology - April 25, 2019 Category: Physiology Source Type: research

Le développement actuel de la télémédecine en Allemagne
Conclusion La promulgation récente d’une loi sur l’organisation des soins en Allemagne, incluant la pratique de la télémédecine, et la mise en place d’une stratégie nationale de développement par le ministère fédéral de la Santé sont des signes en faveur d’un développement plus rapide de la télémédecine. Objectives To assess the state of development of telemedicine in Germany in 2013, identify the strengths and weaknesses of existing organisations, as well as the medium-term outlook. Methods Collection of data from the registry established by the institute für Arbeit und Technik and the statistics ...
Source: European Research in Telemedicine - November 1, 2014 Category: Information Technology Source Type: research

'Dying of heartache?' Heart problems linked to bereavement
Conclusion The study found that people were more likely to have AF for the first time in the weeks immediately after a bereavement, but that this raised risk does not last. Despite the headlines, this does not mean that anyone who's had a bereavement is at immediate risk of "dying of a broken heart". Atrial fibrillation is treatable and not usually life-threatening. Because this was an observational study, we cannot rule out the possibility that factors such as family history of atrial fibrillation or lifestyle factors could have affected the results, although the researcher's conclusion that this is a small poss...
Source: NHS News Feed - April 6, 2016 Category: Consumer Health News Tags: Heart/lungs Mental health Source Type: news

Advice For A Happy, Healthy Life From A Man Dedicated To Those Pursuits
Why do you what you do? Can you trace the source of your professional motivation to a single event or person? As CEO of the American Heart Association and American Stroke Association, I'm privileged to interact with many amazing leaders in cardiovascular medicine, technology, business and beyond. I'm always fascinated by the backstory of how each chose the path into a particular field. When it comes to medical professionals, some simply love the science. Others are drawn by the desire to help people. And then there are those to whom it's personal. Dr. Steven Houser fits all three categories. After four years of playin...
Source: Healthy Living - The Huffington Post - November 22, 2016 Category: Consumer Health News Source Type: news

Viagra could double up as heart failure drug
ConclusionThis systematic review of 24 RCTs indicated PDE5is were more effective than placebos at improving specific measures of heart health and were broadly safe.PDE5is lower blood pressure, so these drugs are currently contraindicated or used with caution in people with cardiovascular disease, including those with low blood pressure and a history of stroke or heart attack, as the effects are unknown. However, various research studies have continued to investigate the possibility that these drugs could have a beneficial effect on heart function. This review has looked into their effect on cardiovascular outcomes further ...
Source: NHS News Feed - October 20, 2014 Category: Consumer Health News Tags: Heart/lungs Medication Source Type: news

Smoking status, clinical presentation and outcomes in obstructive sleep apnoea
Conclusions. Smoking habits seems to be associated with the severity of OSA and CVS outcomes. These results underline the importance of smoking cessation in the treatment of patients with OSA.Supported by ISCIII grant PI12/02175, SADAR/2013 and SEPAR/2013.
Source: European Respiratory Journal - December 23, 2014 Category: Respiratory Medicine Authors: Boldova, A., Carrizo, S., Minchole, E., Moya, V., Forcen, E., Marin, J. M. Tags: 4.2 Sleep and Control of Breathing Source Type: research