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Specialty: Cardiology
Condition: Heart Failure
Education: Study

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Total 2665 results found since Jan 2013.

Prognostic Significance of Blood Urea Nitrogen in Acute Ischemic Stroke.
CONCLUSIONS: Increased BUN at admission is a significant prognostic factor associated with in-hospital mortality in AIS patients, but not with poor discharge outcome. PMID: 28904257 [PubMed - as supplied by publisher]
Source: Circulation Journal - September 12, 2017 Category: Cardiology Authors: You S, Zheng D, Zhong C, Wang X, Tang W, Sheng L, Zheng C, Cao Y, Liu CF Tags: Circ J Source Type: research

Abstract P454: Does Intensive Pulse Pressure control results in lower rates of cardiovascular events? An Analysis of Systolic BP Intervention Trial (SPRINT) database Session Title: Hypertension and Aging and Cerebrovascular Disease and Stroke
Conclusion: In the SPRINT database of 9347 participants, we found that higher PP conferred an increased risk for multiple adverse cardiovascular event. Our study is among the largest US studies of PP and adds further support to the prognostic utility of PP. In addition, the SPRINT database offers a contemporary analysis of the relationship between PP and DBP, which is important given that nature pathophysiology of blood pressure. Current study also strengthen the possibility that DBP
Source: Hypertension - September 14, 2017 Category: Cardiology Authors: Quan Tran Tags: Poster Abstract Presentations Source Type: research

Right Ventricular Stroke Work Index.
In conclusion, lower RVSWI was significantly associated with HF death or HF readmission in patients with PAH or CTEPH. PMID: 30101854 [PubMed - as supplied by publisher]
Source: International Heart Journal - August 15, 2018 Category: Cardiology Tags: Int Heart J Source Type: research

The 10th Biennial Hatter Cardiovascular Institute workshop: cellular protection —evaluating new directions in the setting of myocardial infarction, ischaemic stroke, and cardio-oncology
AbstractDue to its poor capacity for regeneration, the heart is particularly sensitive to the loss of contractile cardiomyocytes. The onslaught of damage caused by ischaemia and reperfusion, occurring during an acute myocardial infarction and the subsequent reperfusion therapy, can wipe out upwards of a billion cardiomyocytes. A similar program of cell death can cause the irreversible loss of neurons in ischaemic stroke. Similar pathways of lethal cell injury can contribute to other pathologies such as left ventricular dysfunction and heart failure caused by cancer therapy. Consequently, strategies designed to protect the ...
Source: Basic Research in Cardiology - October 11, 2018 Category: Cardiology Source Type: research

Compared with matched controls, patients with postoperative atrial fibrillation (POAF) have increased long-term AF after CABG, and POAF is further associated with increased ischemic stroke, heart failure and mortality even after adjustment for AF
ConclusionsPatients with POAF after CABG had three times the incidence of long-term AF compared with both non-POAF patients and matched controls. POAF was associated with long-term ischemic stroke, heart failure, and corresponding mortality even after adjustment for AF during follow-up. The increased overall mortality was partly explained by morbidities associated with POAF.Graphic abstract
Source: Clinical Research in Cardiology - February 7, 2020 Category: Cardiology Source Type: research

Prevalence and determinants of systolic and diastolic cardiac dysfunction and heart failure in acute ischemic stroke patients: The SICFAIL study
ConclusionsA substantial proportion of the study population exhibited subclinical and clinical cardiac dysfunction. SICFAIL provides reliable data on prevalence and determinants of SD, DD, and clinically overt HF in patients with acute IS according to current guidelines, enabling further clarification of its aetiological and prognostic role.
Source: ESC Heart Failure - December 22, 2020 Category: Cardiology Authors: Peter U. Heuschmann, Felipe A. Montellano, Kathrin Ungeth üm, Viktoria Rücker, Silke Wiedmann, Daniel Mackenrodt, Anika Quilitzsch, Timo Ludwig, Peter Kraft, Judith Albert, Caroline Morbach, Stefan Frantz, Stefan Störk, Karl Georg Haeusler Tags: Original Research Article Source Type: research

The CHA2DS2-VASc Score for Risk Stratification of Stroke in Heart Failure With-vs-Without Atrial Fibrillation
A recent study suggested that the CHA2DS2-VASc score can risk stratify heart failure (HF) patients without atrial fibrillation (AF) for stroke. We performed a retrospective analysis using the national Veteran Affairs database to externally validate the findings. Crude incidence rates of end points were calculated. A Cox proportional model was used to study the association between the CHA2DS2-VASc score and outcomes. In HF patients with AF (n  = 17,481) and without AF (n = 36,935), the 1 year incidence rate for ischemic stroke, thromboembolism, thromboembolism (without MI), and death were 2.7 and 2.0%; 10.3 and 7.9%; 4....
Source: The American Journal of Cardiology - July 14, 2021 Category: Cardiology Authors: George R. Marzouka, Harold Rivner, Vijay Mehta, Juan Lopez, Igor Vaz, Fei Tang, Hemant Ishwaran, Jeffrey J. Goldberger Source Type: research

High ward occupancy, bedspacing, and 60  day mortality for patients with myocardial infarction, stroke, and heart failure
ConclusionsPatients with heart failure had higher risk of admission to alternate wards when home ward occupancy was high. These patients may be negatively affected by full wards.
Source: ESC Heart Failure - March 29, 2022 Category: Cardiology Authors: Andreas Asheim, Sara Marie Nilsen, Stina Aam, Kjartan Sarheim Anthun, Fredrik Carlsen, Imre Janszky, Lars Johan Vatten, Johan H åkon Bjørngaard Tags: Original Article Source Type: research

Serum circulating sirtuin 6 as a novel predictor of mortality after acute ischemic stroke
In this study, we aimed at evaluating the prognostic value of serum SIRT6 levels in patients with acute ischemic stroke (AIS). Serum levels of SIRT6, collected within 72 h from symptom-onset, were measured in 317 consecutively enrolled AIS patients from the COSMOS cohort. The primary endpoint of this analysis was 90-day mortality. The independent prognostic value of SIRT6 was assessed with multivariate logistic and Cox proportional regression models. 35 patients (11%) deceased within 90-day follow-up. After adjustment for established risk factors (age, NIHSS, heart failure, atrial fibrillation, and C reactive protein), SIR...
Source: Atherosclerosis - November 28, 2022 Category: Cardiology Authors: Luca Liberale Stefano Ministrini Markus Arnold Yustina M Puspitasari Thomas Pokorny Georgia Beer Natalie Scherrer Juliane Schweizer Mirjam Christ-Crain Fabrizio Montecucco Giovanni G Camici Mira Katan Kahles Source Type: research

Atrial Myopathy and Ischemic Stroke in Heart Failure With Preserved Ejection Fraction
We examined the hypothesis that atrial myopathy may be associated with ischemic stroke in patients with heart failure with preserved ejection fraction. This is an exploratory, post hoc analysis of the Treatment of Preserved Cardiac Function Heart Failure with an Aldosterone Antagonist (TOPCAT) trial. Patients with sinus rhythm documented at baseline electrocardiogram and without known AF were included in this analysis.
Source: The American Journal of Cardiology - July 27, 2023 Category: Cardiology Authors: Kassem Farhat, Khaled Elkholey, Zain Ul Abideen Asad, Stavros Stavrakis Source Type: research

Influence of preload and afterload on stroke volume response to low-dose dobutamine stress in patients with non-ischemic heart failure: A cardiac MR study
Abstract: Background: Lack of increase in left ventricular (LV) stroke volume (SV) during low-dose dobutamine stress (LDD) is attributed to exhausted cardiac contractile reserve in failing heart. However, the role of the afterload and preload in SV changes is underestimated. The aim of the study was to investigate the effects of LDD on preload reserve and afterload in patients with non-ischemic heart failure.Methods: 58 patients (age 62years) underwent LDD (up to 20μg/kg/min) using cardiac magnetic resonance.Results: LV-SV increased by 27% in 24 patients (p
Source: International Journal of Cardiology - December 12, 2011 Category: Cardiology Authors: Alessandro Pingitore, Giovanni Donato Aquaro, Valentina Lorenzoni, Maddalena Gallotta, Daniele De Marchi, Sabrina Molinaro, Valentina Cospite, Claudio Passino, Michele Emdin, Massimo Lombardi, Vincenzo Lionetti, Antonio L'Abbate Tags: Original Articles Source Type: research

Overnight Effects of Obstructive Sleep Apnea and Its Treatment on Stroke Volume in Patients with Heart Failure
Conclusions In patients with HF, co-existing OSA causes overnight declines in SV and CO that are prevented through reversal of OSA by CPAP.　
Source: Canadian Journal of Cardiology - January 17, 2015 Category: Cardiology Source Type: research

Rationale and design of a randomized, double‐blind, event‐driven, multicentre study comparing the efficacy and safety of oral rivaroxaban with placebo for reducing the risk of death, myocardial infarction or stroke in subjects with heart failure and significant coronary artery disease following an exacerbation of heart failure: the COMMANDER HF trial
ConclusionCOMMANDER HF is the first prospective study of a target‐specific oral antithrombotic agent in HF. It will provide important information regarding rivaroxaban use following an HF event in an HF‐rEF patient population with coronary artery disease.
Source: European Journal of Heart Failure - April 27, 2015 Category: Cardiology Authors: Faiez Zannad, Barry Greenberg, John G.F. Cleland, Mihai Gheorghiade, Dirk J. van Veldhuisen, Mandeep R. Mehra, William M. Byra, Min Fu, Roger M. Mills Tags: Original Article Source Type: research

Influence of Left Ventricular Stroke Volume on Incident Heart Failure in a Population with Preserved Ejection Fraction (From the Strong Heart Study)
At a given level of left ventricular (LV) systolic function, LV pump performance (assessed by stroke index [SVi]) may differ, depending on LV size. We evaluated whether low SVi may be considered a marker of risk for incident congestive heart failure (HF), independent of LV geometry and systolic function, assessed by ejection fraction (EF) or midwall fractional shortening (MFS), in a large population-based sample with normal EF. Clinical and echocardiographic data from the second Strong Heart Study (SHS) exam, including 2,885 American Indians (59 ±8 years; 63% women) with normal EF (EF≥51% in men and EF≥55% in women) a...
Source: The American Journal of Cardiology - January 4, 2017 Category: Cardiology Authors: Marina De Marco, Eva Gerdts, Costantino Mancusi, Mary J. Roman, Mai Tone L ønnebakken, Elisa T. Lee, Barbara V. Howard, Richard B. Devereux, Giovanni de Simone Source Type: research