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Specialty: Endocrinology
Condition: Heart Failure
Education: Study
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Total 271 results found since Jan 2013.
Cardiovascular outcomes and rates of fractures and falls among patients with brand-name versus generic L-thyroxine use
ConclusionsWe found no significant differences in cardiovascular outcomes and rates of falls and fractures for patients who filled brand versus generic L-thyroxine.
Source: Endocrine - June 5, 2021 Category: Endocrinology Source Type: research
Electronic Medical Record Risk Modeling of Cardiovascular Outcomes Among Patients with Type 2 Diabetes
ConclusionsThe Ochsner model overestimated 5-year CHD risk, but had relatively higher calibration than the other models in CHD. Risk equations fitted for local populations improved cardiovascular risk stratification for patients with T2DM. Application of machine learning simplified the models compared to “generalized” risk equations.
Source: Diabetes Therapy - June 18, 2021 Category: Endocrinology Source Type: research
Nonalcoholic Fatty Liver Disease, Liver Fibrosis and Cardiovascular Disease in the Adult US Population
ConclusionsIn this population-based study, we did not identify an independent association between steatosis and fibrosis and CVD. Large prospective cohort studies are needed to provide a more definitive evidence on this topic.
Source: Frontiers in Endocrinology - July 26, 2021 Category: Endocrinology Source Type: research
Predictive Value of Free Triiodothyronine to Free Thyroxine Ratio in Euthyroid Patients With Myocardial Infarction With Nonobstructive Coronary Arteries
ConclusionsLow level of fT3/fT4 ratio was strongly associated with a poor prognosis in euthyroid patients with MINOCA. Routine assessment of fT3/fT4 ratio may facilitate risk stratification in this specific population.
Source: Frontiers in Endocrinology - July 28, 2021 Category: Endocrinology Source Type: research
Hypothyroidism is associated with clinical outcomes in patients with acute myocardial infarction: subgroup analysis of China PEACE study
ConclusionCompared with euthyroid status, hypothyroid status has an independent predicting value for adverse cardiovascular events in AMI patients. Further investigations are required to illustrate whether treatment of thyroid dysfunction could improve the prognosis of AMI patients.
Source: Endocrine - September 15, 2021 Category: Endocrinology Source Type: research
Triglyceride and Glucose Index and Sex Differences in Relation to Major Adverse Cardiovascular Events in Hypertensive Patients Without Diabetes
ConclusionWe found the TyG index was associated with MACEs in the hypertensive patients, and there was no gender difference between the TyG index and MACEs.
Source: Frontiers in Endocrinology - November 5, 2021 Category: Endocrinology Source Type: research
Rating the importance of outcomes from diabetes trials. A survey of patients ’ and doctors’ opinions
ConclusionThe current study suggest that patients and doctors weigh some diabetic outcomes used as part of composite endpoints in clinical diabetes trials differently. These findings call for more studies on patient reported outcomes and patient education for improved personal care.Highlights• We performed this study to assess how patients and practicing physicians rate the importance of outcomes commonly used in diabetes trials.• We found that patients and doctors rate the importance of some outcomes used in clinical diabetes trials differently.• These findings suggest that shared decision making is pivotal when tak...
Source: Journal of Diabetes and Metabolic Disorders - November 25, 2021 Category: Endocrinology Source Type: research
Challenges in the Management of Atrial Fibrillation With Subclinical Hyperthyroidism
Subclinical thyroid disorders have a high prevalence among older individuals and women. Subclinical hypothyroidism is diagnosed by elevated serum levels of thyroid-stimulating hormone (TSH) with thyroxine levels within the reference range, and subclinical hyperthyroidism is diagnosed by low TSH in conjunction with thyroxine and triiodothyronine levels within reference ranges. Atrial fibrillation is the most commonly diagnosed cardiac arrhythmia and has been associated with an increased risk of mortality, heart failure, stroke, and depression. Mechanistic data from animal and human physiology studies as well as observationa...
Source: Frontiers in Endocrinology - January 4, 2022 Category: Endocrinology Source Type: research
Cardiovascular risk prediction in type 2 diabetes: a comparison of 22 risk scores in primary care settings
Conclusions/interpretationCVD risk prediction scores could not accurately identify individuals with type 2 diabetes who experienced a CVD event in the 10 years of follow-up. All 22 evaluated models had a comparable and modest discriminative ability.Graphical abstract
Source: Diabetologia - January 15, 2022 Category: Endocrinology Source Type: research
Gestational Diabetes Mellitus and the Risks of Overall and Type-Specific Cardiovascular Diseases: A Population- and Sibling-Matched Cohort Study
CONCLUSIONSA history of GDM was associated with increased risks of overall and specific CVDs. Increased risks were partly explained by subsequent type 2 diabetes, and the need to identify other pathways remains important. Continuous monitoring of women with a history of GDM, especially those with prepregnancy obesity or maternal history of CVD, may provide better opportunities to reduce their cardiovascular risk.
Source: Diabetes Care - November 11, 2021 Category: Endocrinology Source Type: research
Cluster Analysis of Cardiovascular Phenotypes in Patients With Type 2 Diabetes and Established Atherosclerotic Cardiovascular Disease: A Potential Approach to Precision Medicine
CONCLUSIONSIn patients with T2DM and ASCVD, cluster analysis identified four clinically distinct groups. Further cardiovascular phenotyping is warranted to inform patient care and optimize clinical trial designs.
Source: Diabetes Care - October 29, 2021 Category: Endocrinology Source Type: research
Causal associations between circulating adipokines and cardiovascular disease: A Mendelian randomization study
CONCLUSIONS: Our findings reveal the causal association between resistin and AF, probably acting through blood pressure, and suggest potential causal associations between chemerin and CAD, RBP4 and HF.PMID:35134201 | DOI:10.1210/clinem/dgac048
Source: The Journal of Clinical Endocrinology and Metabolism - February 8, 2022 Category: Endocrinology Authors: Delong Chen Yuxuan Zhang Abuduwufuer Yidilisi Yi Xu Qichao Dong Jun Jiang Source Type: research
HDL cholesterol is a protective predictor in the development and progression of retinopathy in type 1 diabetes: a 15-year follow-up study
Despite the declining trend of new visual impairment and blindness due to diabetes in developed countries by the increasing use of anti-vascular endothelial growth factor (anti-VEGF) agents and telemedicine implementation in its systematic screening over the past decade [1,2], diabetic retinopathy (DR), a common and specific microvascular complication of diabetes, is still the leading cause of blindness in patients with type 1 diabetes (T1DM) and also related to increased risk of life-threatening systemic vascular complications, including stroke, coronary heart disease, and heart failure [3,4,5].
Source: Diabetes Research and Clinical Practice - March 2, 2022 Category: Endocrinology Authors: Martina Tomi ć, Romano Vrabec, Tomislav Bulum, Spomenka Ljubić Source Type: research
Cardiovascular risk prediction in type 2 diabetes: a comparison of 22 risk scores in primary care settings
Conclusions/interpretationCVD risk prediction scores could not accurately identify individuals with type 2 diabetes who experienced a CVD event in the 10 years of follow-up. All 22 evaluated models had a comparable and modest discriminative ability.Graphical abstract
Source: Diabetologia - March 13, 2022 Category: Endocrinology Source Type: research
Impact of diabetes mellitus on the outcomes of subjects with hypertrophic cardiomyopathy: a nationwide cohort study
Hypertrophic cardiomyopathy (HCM) is a relatively common genetic cardiomyopathy caused by sarcomeric gene mutations with an assumed prevalence of 1 in 200 persons,[1] and is characterized by left ventricular hypertrophy unexplained by other secondary causes. The clinical course of HCM is complicated by sudden cardiac death, heart failure, atrial fibrillation, and embolic stroke.[2 –4] With advances in management strategies including implantable cardioverter-defibrillators and anticoagulation, subjects with hypertrophic cardiomyopathy (HCM) are benefiting from extended longevity.
Source: Diabetes Research and Clinical Practice - March 18, 2022 Category: Endocrinology Authors: Hyun-Jung Lee, Hyung-Kwan Kim, Bong-Seong Kim, Kyung-Do Han, Tae-Min Rhee, Jun-Bean Park, Heesun Lee, Seung-Pyo Lee, Yong-Jin Kim Source Type: research
