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Total 449 results found since Jan 2013.

Smoking and Atherosclerosis: Mechanisms of Disease and New Therapeutic Approaches.
Abstract It has been clear that at least 1 billion adults worldwide are smokers and at least 700 million children are passive smokers at home. Smoking exerts a detrimental effect to many organ systems and is responsible for illnesses such as lung cancer, pneumonia, chronic obstructive pulmonary disease, cancer of head and neck, cancer of the urinary and gastrointestinal tract, periodontal disease, cataract and arthritis. Additionally, smoking is an important modifiable risk factor for the development of cardiovascular disease such as coronary artery disease, stable angina, acute coronary syndromes, sudden death, s...
Source: Current Medicinal Chemistry - August 26, 2014 Category: Chemistry Authors: Siasos G, Tousoulis D, Michalea S, Oikonomou E, Vavuranakis M, Athanasiou D, Tourikis P, Gouliopoulos N, Miliou A, Mazaris S, Papavassiliou AG, Stefanadis C Tags: Curr Med Chem Source Type: research

The Tell-Tale Heart: Molecular and Cellular Responses to Childhood Anthracycline Exposure.
Abstract Since the modern era of cancer chemotherapy that began in the mid 1940's, survival rates for children afflicted with cancer have steadily improved from 10% to current rates that approach 80%. Unfortunately, many long-term survivors of pediatric cancer develop chemotherapy-related health effects; 25% are afflicted with a severe or life-threatening medical condition, with cardiovascular disease being a primary risk. Childhood cancer survivors have markedly elevated incidences of stroke, congestive heart failure (CHF), coronary artery disease (CAD), and valvular disease. Their cardiac mortality is 8.2 times ...
Source: American Journal of Physiology. Heart and Circulatory Physiology - September 12, 2014 Category: Physiology Authors: Lindsey ML, Lange RA, Parsons H, Andrews T, Aune GJ Tags: Am J Physiol Heart Circ Physiol Source Type: research

A systematic review on discharge care program for patients with sub-acute conditions.
Conclusion: Standard guidelines for discharge care program need to be developed. In addition, well controlled RCT studies with physical outcomes should be further investigated. International Journal of Evidence-Based Healthcare (C) 2014 The Joanna Briggs Institute
Source: International Journal of Evidence-Based Healthcare - September 1, 2014 Category: Nursing Tags: Abstracts of Posters: Evidence Synthesis: PDF Only Source Type: research

Fruit and vegetable intake and rate of heart failure: a population‐based prospective cohort of women
ConclusionsIn this population‐based prospective cohort study of women, higher total consumption of fruit and vegetables was inversely associated with the incidence of heart failure.
Source: European Journal of Heart Failure - November 1, 2014 Category: Cardiology Authors: Susanne Rautiainen, Emily B. Levitan, Murray A. Mittleman, Alicja Wolk Tags: Original Article Source Type: research

The tell-tale heart: molecular and cellular responses to childhood anthracycline exposure
Since the modern era of cancer chemotherapy that began in the mid-1940s, survival rates for children afflicted with cancer have steadily improved from 10% to current rates that approach 80% (60). Unfortunately, many long-term survivors of pediatric cancer develop chemotherapy-related health effects; 25% are afflicted with a severe or life-threatening medical condition, with cardiovascular disease being a primary risk (96). Childhood cancer survivors have markedly elevated incidences of stroke, congestive heart failure (CHF), coronary artery disease, and valvular disease (96). Their cardiac mortality is 8.2 times higher tha...
Source: AJP: Heart and Circulatory Physiology - November 15, 2014 Category: Cardiology Authors: Lindsey, M. L., Lange, R. A., Parsons, H., Andrews, T., Aune, G. J. Tags: REVIEW Source Type: research

Androgen deprivation therapy and cardiovascular risk in chinese patients with nonmetastatic carcinoma of prostate.
Conclusion. ADT in Chinese patients with nonmetastatic prostate cancer with no previously documented cardiovascular disease was associated with subsequent development of cardiovascular events. PMID: 24803931 [PubMed]
Source: Journal of Oncology - November 17, 2014 Category: Cancer & Oncology Tags: J Oncol Source Type: research

Assessment of public awareness on chronic obstructive pulmonary disease in Slovenia
ConclusionsPublic awareness and knowledge about COPD is low and COPD is not considered as relevant public health problem. Strategies to inform and educate Slovenian public about COPD are urgently needed.
Source: European Respiratory Journal - December 23, 2014 Category: Respiratory Medicine Authors: Farkas, J., Lainscak, M. Tags: 1.6 General Practice and Primary Care Source Type: research

Withdrawal of Life-Sustaining Treatment: Patient and Proxy Agreement: A Secondary Analysis of “Contracts, Covenants, and Advance Care Planning”
This study explored patient and proxy decisions related to mechanical ventilator withdrawal in scenarios characterizing 3 distinct disease trajectories (cancer, stroke, and heart failure [HF]) with different prognoses. The relationship between patient directives, modification of directives, prognosis, trust, and EOL decisions were examined. Methods: This secondary analysis of data obtained in the “Contracts, Covenants, and Advance Care Planning” study included a sample of 110 subjects with 50 patient-proxy pairs. Patient and proxy agreement was assessed in response to questions regarding mechanical ventilator withdrawa...
Source: Dimensions of Critical Care Nursing - February 6, 2015 Category: Nursing Tags: Research DIMENSION Source Type: research

Long-term Mortality Risk After Hyperglycemic Crisis Episodes in Geriatric Patients With Diabetes: A National Population-Based Cohort Study.
CONCLUSIONS: Patients with diabetes had a higher mortality risk after HCE during the first 6 years of follow-up. Referral for proper education, better access to medical care, effective communication with a health care provider, and control of comorbidities should be done immediately after HCE. PMID: 25665811 [PubMed - as supplied by publisher]
Source: Diabetes Care - February 9, 2015 Category: Endocrinology Authors: Huang CC, Weng SF, Tsai KT, Chen PJ, Lin HJ, Wang JJ, Su SB, Chou W, Guo HR, Hsu CC Tags: Diabetes Care Source Type: research

Engaging patients to recover life projectuality: an Italian cross-disease framework
Conclusions QoL deeply depends on the patient ability to engage in their care and on the health expectations they have. We propose a model of the relation between patient engagement and patients’ trajectories in critical event responses and use it to illustrate a new perspective on QoL. This research showed the heuristic value patient engagement as a is a key concept in the promotion of a patients’ experience-sensitive QoL interventions and assessment measures.
Source: Quality of Life Research - April 21, 2015 Category: Health Management Source Type: research

Long-term Mortality Risk After Hyperglycemic Crisis Episodes in Geriatric Patients With Diabetes: A National Population-Based Cohort Study
CONCLUSIONS Patients with diabetes had a higher mortality risk after HCE during the first 6 years of follow-up. Referral for proper education, better access to medical care, effective communication with a health care provider, and control of comorbidities should be done immediately after HCE.
Source: Diabetes Care - April 23, 2015 Category: Endocrinology Authors: Huang, C.-C.; Weng, S.-F.; Tsai, K.-T.; Chen, P.-J.; Lin, H.-J.; Wang, J.-J.; Su, S.-B.; Chou, W.; Guo, H.-R.; Hsu, C.-C. Tags: Clinical Care/Education/Nutrition/Psychosocial Research Source Type: research

Hospitalization after fainting can do more harm than good
One morning not long ago, my teenage daughter started to black out. After an ambulance ride to our local hospital’s emergency department, an electrocardiogram, and some bloodwork, she was sent home with a follow-up doctor appointment. We got the good news that Alexa is perfectly healthy, but should avoid getting too hungry or thirsty so she doesn’t faint again. And I’m feeling lucky that she didn’t need to be hospitalized, because a research letter in this week’s JAMA Internal Medicine points out that hospitalization for low-risk fainting can do more harm than good. Doctors use something called th...
Source: New Harvard Health Information - April 22, 2015 Category: Consumer Health News Authors: Heidi Godman Tags: Health fainting San Francisco Syncope Rule Source Type: news

Subsequent mortality after hyperglycemic crisis episode in the non-elderly: a national population-based cohort study
Abstract Hyperglycemic crisis episodes (HCEs)—diabetic ketoacidosis and the hyperosmolar hyperglycemic state—are the most serious acute metabolic complications of diabetes. We aimed to investigate the subsequent mortality after HCE in the non-elderly diabetic which is still unclear. This retrospective national population-based cohort study reviewed, in Taiwan’s National Health Insurance Research Database, data from 23,079 non-elder patients (≤65 years) with new-onset diabetes between 2000 and 2002: 7693 patients with HCE and 15,386 patients without HCE (1:2). Both groups were compared, and follow-up p...
Source: Endocrine - June 27, 2015 Category: Endocrinology Source Type: research

Use of Nonsteroidal Anti-Inflammatory Drugs and Risk of Chronic Kidney Disease in Subjects With Hypertension: Nationwide Longitudinal Cohort Study Kidney
Limited studies have examined the effects of nonsteroidal anti-inflammatory drug (NSAID) use on the risk of chronic kidney disease (CKD), especially in subjects with hypertension. Using National Health Insurance claims data in Taiwan, we conducted a propensity score–matched cohort study to investigate the relationship between NSAID use and CKD in subjects with hypertension. A total of 31976 subjects were included in this study: subjects not taking any NSAIDs in 2007 (n=10782); subjects taking NSAIDs for 1 to 89 days in 2007 (n=10605); and subjects taking NSAIDs for ≥90 days in 2007 (n=10589). We performed multivar...
Source: Hypertension - August 12, 2015 Category: Cardiology Authors: Hsu, C.-C., Wang, H., Hsu, Y.-H., Chuang, S.-Y., Huang, Y.-W., Chang, Y.-K., Liu, J.-S., Hsiung, C. A., Tsai, H.-J. Tags: Clinical Studies Kidney Source Type: research

How Air Pollution Contributes to Millions of Early Deaths
Outdoor air pollution leads to more than 3 million premature deaths each year, and more than two thirds of them occur in China and India, according to new research. The authors estimate that without government intervention, the total number of deaths could double by 2050. The study, published in the journal Nature, identifies particulate matter as the prime pollutant leading to premature mortality. Particulate matter, a substance formed as a combination of different materials released into the air, is thought to be harmful to human health once it exceeds 2.5 micrometers in diameter. Researchers also identified ozone as a c...
Source: TIME.com: Top Science and Health Stories - September 16, 2015 Category: Consumer Health News Authors: Justin Worland Tags: Uncategorized Air Pollution climate change early death Environment fertilizer particulate matter premature death public health Research Source Type: news