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Condition: Chlamydia

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Total 43 results found since Jan 2013.

Novel Inflammatory Biomarkers and Their Correlation to Chlamydia pneumoniae Titres in Acute Ischemic Stroke
Conclusions: The study demonstrated high levels of hsp 65 and neopterin levels in AIS correlated to significantly elevated IgA titres of C pneumoniae. Elevated levels of hsp 65 were associated with stroke severity.
Source: Journal of Stroke and Cerebrovascular Diseases - September 29, 2014 Category: Neurology Authors: M.V. Padma Srivastava, Ashu Bhasin, Rama Chaudhry, Sakshi Sharma, Vivekanandhan Subbaiah, Rohit Bhatia, Manjari Tripathi Tags: Original Articles Source Type: research

Novel Inflammatory Biomarkers and Their Correlation to Titres in Acute Ischemic Stroke
Young stroke patients constitute 15%-30% of all stroke patients in India as against 3.0%-8.5% reported from the West. The mechanisms for stroke in the young may include unconventional risk factors such as infections. We aimed to investigate the role (if any) of Chlamydia pneumoniae antibodies in young patients with acute ischemic stroke (AIS). Several proinflammatory cytokines and biomarkers are released early after the onset of brain ischemia. We assessed the role of heat shock protein (hsp) 65, neopterin, and myeloperoxidase upregulation after AIS in predicting stroke severity.
Source: Journal of Stroke and Cerebrovascular Diseases - October 1, 2014 Category: Neurology Authors: M.V. Padma Srivastava, Ashu Bhasin, Rama Chaudhry, Sakshi Sharma, Vivekanandhan Subbaiah, Rohit Bhatia, Manjari Tripathi Tags: Original Article Source Type: research

Potential association between bacterial infections and ischemic stroke based on fifty case-control studies: A systematic review and meta-analysis
CONCLUSIONS: In this meta-analysis, a significant relationship was observed between infection by three bacteria such as C. pneumoniae, H. pylori, and M. tuberculosis with the occurrence of ischemic stroke. Furthermore, due to the similarity between TLRVYK domain in β2-glycoprotein-I and TLRVYK peptide in various of microorganisms, produced antibodies against pathogens interact with β2-glycoprotein-I, hence the cross-reaction phenomenon increases the positive relationship between infectious diseases and ischemic stroke.PMID:35592534 | PMC:PMC9112101 | DOI:10.1016/j.nmni.2022.100980
Source: Atherosclerosis - May 20, 2022 Category: Cardiology Authors: M Keikha M Karbalaei Source Type: research

Previous infection and the risk of ischaemic stroke in Italy: the IN2 study
ConclusionsEarly previous infections and persistent chronic infection of C. pneumoniae could contribute to increase the risk of ischaemic stroke significantly, in the elderly especially.
Source: European Journal of Neurology - December 2, 2014 Category: Neurology Authors: D. Consoli, S. Vidale, U. Aguglia, P. Bassi, A. Cavallini, F. Galati, D. Guidetti, N. Marcello, G. Micieli, G. Pracucci, M. Rasura, A. Siniscalchi, R. Sterzi, D. Toni, D. Inzitari Tags: Original Article Source Type: research

The influence of previous infections and antichlamydia pneumoniae seropositivity on functional outcome in ischemic stroke patients: results from the IN2 study
Abstract Although a growing attention is being paid to acute ischemic stroke patients, the correlation between clinical outcome and infectious events in this population has been poorly investigated. 749 ischemic stroke (mean age 71 years old, males 56 %) patients were enrolled in this prospective case–control study by 11 Italian Stroke Units. Demographic data, vascular risk factors, previous infections and post-stroke infections (PSIs) were recorded. Blood samples were collected and the enzyme-linked immunoassay was chosen to measure Chlamydia pneumoniae IgG and IgA plasma antibodies (antibody titers were clas...
Source: Journal of Neurology - March 25, 2015 Category: Neurology Source Type: research

Cross-Reactivity as a Mechanism Linking Infections to Stroke
The relevance of infections as risk factor for cerebrovascular disease is being increasingly recognized. Nonetheless, the pathogenic link between the two entities remains poorly understood. Consistent with recent advances in medicine, the present work addresses the hypothesis that infection-induced immune responses may affect human proteins associated with stroke. Applying established procedures in bioinformatics, the pathogen antigens and the human proteins were searched for common sequences using pentapeptides as probes. The data reported demonstrate massive peptide sharing between infectious pathogens—such as Chlamydi...
Source: Frontiers in Neurology - May 13, 2019 Category: Neurology Source Type: research

Carotid intima media thickness and blood biomarkers of atherosclerosis in patients after stroke or myocardial infarction.
CONCLUSIONS: Our study supports linear correlations between CIMT and IC and hs-CRP levels. However, these associations seem to depend on the type of vascular burden. PMID: 28051279 [PubMed - in process]
Source: Croatian Medical Journal - December 30, 2016 Category: Journals (General) Authors: Kurkowska-Jastrzebska I, Karlinski MA, Błazejewska-Hyzorek B, Sarzynska-Dlugosz I, Filipiak KJ, Czlonkowska A Tags: Croat Med J Source Type: research

Infectious burden and cognitive function: The Northern Manhattan Study
Conclusion: A measure of IB associated with stroke risk and atherosclerosis was independently associated with cognitive performance in this multiethnic cohort. Past infections may contribute to cognitive impairment.
Source: Neurology - March 25, 2013 Category: Neurology Authors: Katan, M., Moon, Y. P., Paik, M. C., Sacco, R. L., Wright, C. B., Elkind, M. S. V. Tags: All Infections, All Cerebrovascular disease/Stroke, All Cognitive Disorders/Dementia ARTICLE Source Type: research

Infections and Chlamydia pneumoniae antibodies influence the functional outcome in thrombolysed strokes
Thrombolysis is effective in ischemic stroke patients, but some factors influence its benefit. Previous infections could increase the risk of ischemic stroke by an activation of systemic inflammation. We analysed the influence of previous infections and Chlamydia pneumoniae serology on functional outcome in thrombolysed stroke patients. Methods: Consecutive thrombolysed stroke patients admitted during calendar year 2011 were analysed. Demographics, vascular risk factors, clinical and aetiological data were registered.
Source: Journal of the Neurological Sciences - August 2, 2017 Category: Neurology Authors: Domenico Consoli, Simone Vidale, Marco Arnaboldi, Anna Cavallini, Arturo Consoli, Franco Galati, Donata Guidetti, Giuseppe Micieli, Maurizia Rasura, Roberto Sterzi, Danilo Toni, Domenico Inzitari Source Type: research

Chlamydia pneumoniae infection and cerebrovascular disease: a systematic review and meta-analysis
Conclusion: Association between C.pneumoniae infection and CV disease depends on the analytical method adopted, which seems stronger with stroke due to large artery atherosclerosis. Establishing a causal relationship between C.peumoniae infection and CV disease will require more prospective studies with combination of techniques and stratified by etiological subtypes.
Source: BMC Neurology - November 21, 2013 Category: Neurology Authors: Juan ChenMeijia ZhuGaoting MaZhangning ZhaoZhongwen Sun Source Type: research

Intracranial Large Artery Stenosis and Past Infectious Exposures: Results From the NOMAS Cohort
CONCLUSIONS: Chronic infectious exposures, specifically herpes simplex virus 2 and cytomegalovirus were associated with asymptomatic ILAS as seen on magnetic resonance angiogram imaging. This may represent an additional target of intervention in the ongoing effort to stem the substantial global burden of strokes related to ILAS.PMID:35105181 | DOI:10.1161/STROKEAHA.121.036793
Source: Herpes - February 2, 2022 Category: Infectious Diseases Authors: Amol Mehta Farid Khasiyev Clinton B Wright Tatjana Rundek Ralph L Sacco Mitchell S V Elkind Jose Gutierrez Source Type: research

Infectious Burden and Cognitive Decline in the Northern Manhattan Study
ConclusionA quantitative stroke risk‐weighted measure of IB explained variability in baseline executive function performance and associated with decline in memory. Past exposure to common infections may contribute to vascular cognitive impairment and warrants further study.
Source: Journal of the American Geriatrics Society - August 20, 2015 Category: Geriatrics Authors: Clinton B. Wright, Hannah Gardener, Chuanhui Dong, Mitsuhiro Yoshita, Charles DeCarli, Ralph L. Sacco, Yaakov Stern, Mitchell S. V. Elkind Tags: Clinical Investigations Source Type: research

Pivotal pathogenic and biomarker role of Chlamydia Pneumoniae in neurovascular diseases.
Abstract Chlamydia pneumoniae(C.Pn) is an obligatory intracellular bacterium that is associated with respiratory tract infections like pneumonia, pharyngitis and bronchitis. It has also been implicated in cerebrovascular (stroke) as well as cardiovascular diseases. The most possible pathway via which C.Pn elicits its pathogenesis could be via activation of human vascular smooth muscle cells (VSMCs) proliferation resulting in the stimulation of toll like receptor-4 (TLR-4) and/or phospho-44/42(p44/p42) mitogen-activated protein kinases (MAPK). It is also established that tyrosine phosphorylation of IQ domain GTPase...
Source: Current Neurovascular Research - July 17, 2018 Category: Neurology Authors: Richard SA Tags: Curr Neurovasc Res Source Type: research

Health maintenance in women.
Abstract The health maintenance examination is an opportunity to focus on disease prevention and health promotion. The patient history should include screening for tobacco use, alcohol misuse, intimate partner violence, and depression. Premenopausal women should receive preconception counseling and contraception as needed, and all women planning or capable of pregnancy should take 400 to 800 mcg of folic acid per day. High-risk sexually active women should be counseled on reducing the risk of sexually transmitted infections, and screened for chlamydia, gonorrhea, and syphilis. All women should be screened for huma...
Source: American Family Physician - January 1, 2013 Category: Primary Care Authors: Riley M, Dobson M, Jones E, Kirst N Tags: Am Fam Physician Source Type: research