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Cancer: Glioma
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Total 252 results found since Jan 2013.
Assessment of structural disconnections in gliomas: comparison of indirect and direct approaches
AbstractGliomas are amongst the most common primary brain tumours in adults and are often associated with poor prognosis. Understanding the extent of white matter (WM) which is affected outside the tumoral lesion may be of paramount importance to explain cognitive deficits and the clinical progression of the disease. To this end, we explored both direct (i.e., tractography based) and indirect (i.e., atlas-based) approaches to quantifying WM structural disconnections in a cohort of 44 high- and low-grade glioma patients. While these methodologies have recently gained popularity in the context of stroke and other pathologies...
Source: Anatomy and Embryology - May 3, 2022 Category: Anatomy Source Type: research
Awake Mapping With Transopercular Approach in Right Insular–Centered Low-Grade Gliomas Improves Neurological Outcomes and Return to Work
CONCLUSION:
This is the first study comparing asleep vs awake surgery for right insula–centered LGG. Despite similar extent of resection, functional outcomes were significantly better in awake patients by avoiding permanent neurological impairment and by increasing RTW. These results support the mapping of higher-order functions during awake procedure.
Source: Neurosurgery - June 22, 2022 Category: Neurosurgery Tags: Research—Human—Clinical Studies: Tumor Source Type: research
< mml:math xmlns:mml="http://www.w3.org/1998/Math/MathML" > < mml:mrow > < mml:msubsup > < mml:mi > T < /mml:mi > < mml:mn > 2 < /mml:mn > < mml:mo > ' < /mml:mo > < /mml:msubsup > < /mml:mrow > < /mml:math > mapping of the brain from water-unsuppressed < sup > 1 < /sup > H-MRSI and turbo spin-echo data
CONCLUSIONS: High-quality T 2 ' $$ {\mathrm{T}}_2^{\prime } $$ maps can be obtained from water-unsuppressed 1 H-MRSI and TSE data using the proposed method. With further development, this method may lay a foundation for simultaneously imaging oxygenation and neurometabolic alterations of brain disorders.PMID:35844075 | DOI:10.1002/mrm.29386
Source: Magnetic Resonance in Medicine - July 18, 2022 Category: Radiology Authors: Tianxiao Zhang Rong Guo Yudu Li Yibo Zhao Yao Li Zhi-Pei Liang Source Type: research
Diffuse low-grade glioma misdiagnosed as acute cerebral infarction: A case report
We report a case of DLGG detected by computed tomography and magnetic resonance imaging (MRI).
Patient concerns:
A 58-year-old man suddenly phantom smells for half an hour and was previously healthy.
Diagnoses:
Computed tomography findings showed a leaf-shaped slightly hypodense shadow in the right temporal lobe with no obvious mass effect and an unclear boundary. MRI findings showed diffuse and slightly longer T1-weighted imaging (T1WI)/T2-weighted imaging (T2WI)signal in the right temporal lobe and hippocampus, slight hyperintensity on diffusion-weighted imaging, diffuse swelling in the right temporal lobe ...
Source: Medicine - September 2, 2022 Category: Internal Medicine Tags: Research Article: Clinical Case Report Source Type: research
Tracers progress for positron emission tomography imaging of glial-related disease
J Biomed Res. 2022 Jun 28:1-15. doi: 10.7555/JBR.36.20220017. Online ahead of print.ABSTRACTGlial cells play an essential part in the neuron system. They can not only serve as structural blocks in the human brain but also participate in many biological processes. Extensive studies have shown that astrocytes and microglia play an important role in neurodegenerative diseases, such as Alzheimer's disease, Parkinson's disease, Huntington's disease, as well as glioma, epilepsy, ischemic stroke, and infections. Positron emission tomography is a functional imaging technique providing molecular-level information before anatomic ch...
Source: Biomed Res - September 22, 2022 Category: Research Authors: Haoran Jia Tianwu Xie Source Type: research
Applicability and efficacy of ultrasound elastography in neurosurgery: a systematic review of the literature
CONCLUSIONS: This systematic review showed that, despite the lack of strong evidences, USE is a valid intraoperative tool, especially in oncological neurosurgery.PMID:36239425 | DOI:10.23736/S0390-5616.22.05866-0
Source: Journal of Neurosurgical Sciences - October 14, 2022 Category: Neurosurgery Authors: Ismail Zaed Giuseppe M Della Pepa Delia Cannizzaro Grazia Menna Andrea Cardia Source Type: research
A Chinese female patient with LGI1 and mGluR5 antibodies: A case report
We present a case of AE with dual seropositive antibodies of LGI1 and mGluR5 in a 65-year-old woman who presented with sudden onset left faciobrachial dystonic seizures and unresponsive for 5 hours.
Diagnosis:
The patient was diagnosed with anti-LGI1 AE and anti-mGluR5 AE mainly based on the clinical symptoms and further test of the antibody in serum and cerebral spinal fluid (CSF).
Interventions and outcomes:
The patient was treated with glucocorticoid intravenous drip. We also gave her the therapy of immunoglobulin (25 g q.d) for 5 days and anti-epileptic therapy. She had no more convulsions on the left s...
Source: Medicine - October 28, 2022 Category: Internal Medicine Tags: Research Article: Clinical Case Report Source Type: research
