Next Month in Neurosurgery
No abstract available (Source: Neurosurgery)
Source: Neurosurgery - December 1, 2016 Category: Neurosurgery Tags: Departments Source Type: research

Table Of Contents by Topic
No abstract available (Source: Neurosurgery)
Source: Neurosurgery - December 1, 2016 Category: Neurosurgery Tags: Departments Source Type: research

Calendar of Events
No abstract available (Source: Neurosurgery)
Source: Neurosurgery - December 1, 2016 Category: Neurosurgery Tags: Departments Source Type: research

Journal Club: Outpatient Cervical and Lumbar Spine Surgery is Feasible and Safe: A Consecutive Single Center Series of 1449 Patients: Erratum.
No abstract available (Source: Neurosurgery)
Source: Neurosurgery - December 1, 2016 Category: Neurosurgery Tags: Errata Source Type: research

Elevated Baseline C-Reactive Protein as a Predictor of Outcome After Aneurysmal Subarachnoid Hemorrhage: Data From the Simvastatin in Aneurysmal Subarachnoid Hemorrhage (STASH) Trial: Erratum
No abstract available (Source: Neurosurgery)
Source: Neurosurgery - December 1, 2016 Category: Neurosurgery Tags: Errata Source Type: research

In Reply: Can We Rely on Susceptibility-Weighted Imaging (SWI) for Subthalamic Nucleus Identification in Deep Brain Stimulation Surgery?
No abstract available (Source: Neurosurgery)
Source: Neurosurgery - December 1, 2016 Category: Neurosurgery Tags: Correspondence Source Type: research

Can We Rely on Susceptibility-Weighted Imaging (SWI) for Subthalamic Nucleus Identification in Deep Brain Stimulation Surgery?
No abstract available (Source: Neurosurgery)
Source: Neurosurgery - December 1, 2016 Category: Neurosurgery Tags: Correspondence Source Type: research

In Reply: Lower Risk of Intracranial Arteriovenous Malformation Hemorrhage in Patients With Hereditary Hemorrhagic Telangiectasia
No abstract available (Source: Neurosurgery)
Source: Neurosurgery - December 1, 2016 Category: Neurosurgery Tags: Correspondence Source Type: research

Lower Risk of Intracranial Arteriovenous Malformation Hemorrhage in Patients With Hereditary Hemorrhagic Telangiectasia
No abstract available (Source: Neurosurgery)
Source: Neurosurgery - December 1, 2016 Category: Neurosurgery Tags: Correspondence Source Type: research

Book Review: Neurosurgery Knowledge Update: A Comprehensive Review
No abstract available (Source: Neurosurgery)
Source: Neurosurgery - December 1, 2016 Category: Neurosurgery Tags: Book Reviews Source Type: research

Book Review: Atlas of Emergency Neurosurgery
No abstract available (Source: Neurosurgery)
Source: Neurosurgery - December 1, 2016 Category: Neurosurgery Tags: Book Reviews Source Type: research

Book Review: The Special Field: A History of Neurosurgery at Johns Hopkins
No abstract available (Source: Neurosurgery)
Source: Neurosurgery - December 1, 2016 Category: Neurosurgery Tags: Book Reviews Source Type: research

Does the Open Payments Database Provide Sunshine on Neurosurgery?
CONCLUSION: The OPD details physician interactions with industry and has multiple inaccuracies. Publicly availing inaccurate information through a searchable governmental website that can be accessed by patients and journalists alike has the potential to tarnish individual neurosurgeons and undermine professional credibility. ABBREVIATIONS: CMS, Centers for Medicare & Medicaid Services OPD, Open Payments Database (Source: Neurosurgery)
Source: Neurosurgery - December 1, 2016 Category: Neurosurgery Tags: Special Article Source Type: research

Commentary: Statements of Agreement From the Targeted Evaluation and Active Management (TEAM) Approaches to Treating Concussion Meeting Held in Pittsburgh, October 15-16, 2015
No abstract available (Source: Neurosurgery)
Source: Neurosurgery - December 1, 2016 Category: Neurosurgery Tags: Commentaries Source Type: research

Statements of Agreement From the Targeted Evaluation and Active Management (TEAM) Approaches to Treating Concussion Meeting Held in Pittsburgh, October 15-16, 2015
CONCLUSION: Concussions are characterized by diverse symptoms and impairments and evolving clinical profiles; recovery varies on the basis of modifying factors, injury severity, and treatments. Active and targeted treatments may enhance recovery after concussion. Research is needed on concussion clinical profiles, biomarkers, and the effectiveness and timing of treatments. ABBREVIATIONS: ARS, audience response system CDC, Centers for Disease Control and Prevention DoD, Department of Defense mTBI, mild traumatic brain injury NCAA, National Collegiate Athletic Association NFL, National Football League NIH, National In...
Source: Neurosurgery - December 1, 2016 Category: Neurosurgery Tags: Special Article: Editor's Choice Source Type: research

Evaluation of a New Brain Tissue Probe for Cerebral Blood Flow Monitoring in an Experimental Pig Model
BACKGROUND: Bedside monitoring of cerebral blood flow (CBF) may provide new insights into the pathophysiology of brain injury, allow early detection of secondary ischemia, and help guide therapy. OBJECTIVE: To evaluate a new brain tissue probe for serial CBF monitoring using near-infrared spectroscopy and indocyanine green dye dilution (NeMo Probe) compared with the existing thermal diffusion probe (QFlow 500 Probe). METHODS: In 7 pigs, the NeMo Probe and QFlow 500 Probe were inserted into the subcortical white matter. Parallel measurements were recorded during (1) baseline, (2) hypotension, (3) hypertension, and (4) hyp...
Source: Neurosurgery - December 1, 2016 Category: Neurosurgery Tags: Research-Animal Source Type: research

Biomechanical Evaluation of Lumbar Decompression Adjacent to Instrumented Segments
BACKGROUND: Multilevel lumbar stenosis, in which 1 level requires stabilization due to spondylolisthesis, is routinely treated with multilevel open laminectomy and fusion. We hypothesized that a minimally invasive (MI) decompression is biomechanically superior to open laminectomy and may allow decompression of the level adjacent the spondylolisthesis without additional fusion. OBJECTIVE: To study the mechanical effect of various decompression procedures adjacent to instrumented segments in cadaver lumbar spines. METHODS: Conditions tested were (1) L4-L5 instrumentation, (2) L3-L4 MI decompression, (3) addition of partial...
Source: Neurosurgery - December 1, 2016 Category: Neurosurgery Tags: Research-Laboratory Source Type: research

The Association Between Operating Room Personnel and Turnover With Surgical Site Infection in More Than 12 000 Neurosurgical Cases
CONCLUSION: This study found that patient body mass index and male sex were associated with an increased risk of SSI. Operating room personnel turnover, a modifiable, work flow–related factor, was an independent variable positively correlated with SSI. This study suggests that efforts to reduce operating room turnover may be effective in preventing SSI. ABBREVIATIONS: OR, operating room SSI, surgical site infection (Source: Neurosurgery)
Source: Neurosurgery - December 1, 2016 Category: Neurosurgery Tags: Research-Human-Clinical Studies Source Type: research

Long-Term Outcomes in the Treatment of Classical Trigeminal Neuralgia by Gamma Knife Radiosurgery: A Retrospective Study in Patients With Minimum 2-Year Follow-up
CONCLUSION: GKRS achieved favorable outcomes compared with surgery in terms of pain relief and complication rates in our cohort of patients, notwithstanding decreasing pain-free survival rates over time. We consider GKRS to be an initial treatment in the management of medically intractable TN in selected patients. ABBREVIATIONS: CI, confidence interval GKRS, gamma knife radiosurgery MVD, microvascular decompression RS, radiosurgery TN, trigeminal neuralgia (Source: Neurosurgery)
Source: Neurosurgery - December 1, 2016 Category: Neurosurgery Tags: Research-Human-Clinical Studies Source Type: research

Treatment Practices and Outcomes After Blunt Cerebrovascular Injury in Children
BACKGROUND: Pediatric blunt cerebrovascular injury (BCVI) lacks accepted treatment algorithms, and postinjury outcomes are ill defined. OBJECTIVE: To compare treatment practices among pediatric trauma centers and to describe outcomes for available treatment modalities. METHODS: Clinical and radiographic data were collected from a patient cohort with BCVI between 2003 and 2013 at 4 academic pediatric trauma centers. RESULTS: Among 645 pediatric patients evaluated with computed tomography angiography for BCVI, 57 vascular injuries (82% carotid artery, 18% vertebral artery) were diagnosed in 52 patients. Grade I (58%) and ...
Source: Neurosurgery - December 1, 2016 Category: Neurosurgery Tags: Research-Human-Clinical Studies Source Type: research

Intraoperative Near-Infrared Optical Imaging Can Localize Gadolinium-Enhancing Gliomas During Surgery
CONCLUSION: With the use of Second Window ICG, gadolinium-enhancing tumors can be localized through brain parenchyma intraoperatively. Its utility for margin detection is promising but limited by lower specificity. ABBREVIATIONS: 5-ALA, 5-aminolevulinic acid EPR, enhanced permeability and retention FDA, Food and Drug Administration GBM, glioblastoma ICG, indocyanine green NIR, near-infrared NPV, negative predictive value PPV, positive predictive value ROC, receiver operating characteristic ROI, region of interest SBR, signal-to-background ratio WHO, World Health Organization (Source: Neurosurgery)
Source: Neurosurgery - December 1, 2016 Category: Neurosurgery Tags: Research-Human-Clinical Studies: Editor's Choice Source Type: research

The Effect of Lumbar Spinal Muscle on Spinal Sagittal Alignment: Evaluating Muscle Quantity and Quality
BACKGROUND: The majority of earlier studies of the parameters of sagittal balance did not consider the influence of spinal muscles on spinal sagittal alignment. OBJECTIVE: To analyze the relationship between the paraspinal muscle (quantity and quality) and sagittal alignment in elderly patients. METHODS: We reviewed 50 full-spine lateral standing radiographs and lumbar magnetic resonance images of elderly patients at a single center. The radiographic parameters examined were thoracic kyphosis, lumbar lordosis (LL), sagittal vertical axis, pelvic tilt, sacral slope, and pelvic incidence (PI). The lumbar muscularity (LM; q...
Source: Neurosurgery - December 1, 2016 Category: Neurosurgery Tags: Research-Human-Clinical Studies Source Type: research

Diagnostic Value of Fractal Analysis for the Differentiation of Brain Tumors Using 3-Tesla Magnetic Resonance Susceptibility-Weighted Imaging
BACKGROUND: Susceptibility-weighted imaging (SWI) of brain tumors provides information about neoplastic vasculature and intratumoral micro- and macrobleedings. Low- and high-grade gliomas can be distinguished by SWI due to their different vascular characteristics. Fractal analysis allows for quantification of these radiological differences by a computer-based morphological assessment of SWI patterns. OBJECTIVE: To show the feasibility of SWI analysis on 3-T magnetic resonance imaging to distinguish different kinds of brain tumors. METHODS: Seventy-eight patients affected by brain tumors of different histopathology (low- ...
Source: Neurosurgery - December 1, 2016 Category: Neurosurgery Tags: Research-Human-Clinical Studies Source Type: research

Angiographic Characteristics of Pseudo-occlusion of the Internal Carotid Artery Before and After Stenting
CONCLUSION: Stenotic lesions of pseudo-occlusion of the ICA were classified as single channel and multiple channel. Restricted dilatation of the distal ICA after CAS was more prevalent in the multiple-channel group. Because adverse events tended to be more frequent in the multiple-channel group than in the single-channel group, the indications for CAS should be determined carefully in multiple-channel patients. ABBREVIATIONS: CAS, carotid artery stenting ICA, internal carotid artery (Source: Neurosurgery)
Source: Neurosurgery - December 1, 2016 Category: Neurosurgery Tags: Research-Human-Clinical Studies Source Type: research

Functional Gonadotroph Adenomas: Case Series and Report of Literature
CONCLUSION: An FGA can pose both a diagnostic and a therapeutic challenge. The tumor is often diagnosed as a nonfunctioning macroadenoma after presenting with nonspecific symptoms and is the cause of significant morbidity. An FGA should be considered in the differential diagnosis of patients harboring pituitary adenomas with reproductive dysfunction. Transsphenoidal resection is the initial treatment of choice and can reduce endocrine dysfunction, resolve headaches, improve visual impairment, and provide tissue for detailed analysis. ABBREVIATIONS: FGA, functional gonadotroph adenoma FSH, follicle-stimulating hormone LH...
Source: Neurosurgery - December 1, 2016 Category: Neurosurgery Tags: Research-Human-Clinical Studies Source Type: research

Contribution of Lordotic Correction on C5 Palsy Following Cervical Laminectomy and Fusion
CONCLUSION: Lordotic cervical correction, as measured on upright imaging, was statistically larger in patients who had C5 palsy. The role of deformity correction in C5 palsy deserves further study and may inform intraoperative decision making. ABBREVIATION: CLF, cervical laminectomy and fusion (Source: Neurosurgery)
Source: Neurosurgery - December 1, 2016 Category: Neurosurgery Tags: Research-Human-Clinical Studies Source Type: research

Endoventricular Deep Brain Stimulation of the Third Ventricle: Proof of Concept and Application to Cluster Headache
CONCLUSION: This proof of concept demonstrates the feasibility, safety, and potential efficacy of 3rd V DBS using an endoventricular road that could be applied to treat various diseases involving hypothalamic areas. ABBREVIATIONS: CCH, chronic cluster headache CH, cluster headache DBS, deep brain stimulation HAD, hospital anxiety depression ONS, occipital nerve stimulation PAG, periaqueductal gray matter PH, posterior hypothalamus PVG, periventricular gray matter 3rd V, third ventricle (Source: Neurosurgery)
Source: Neurosurgery - December 1, 2016 Category: Neurosurgery Tags: Research-Human-Clinical Studies Source Type: research

Reconstruction of the Internal Carotid Artery After Treatment of Complex Traumatic Direct Carotid-Cavernous Fistulas With the Willis Covered Stent: A Retrospective Study With Long-Term Follow-up
CONCLUSION: The use of Willis covered stents was confirmed to be effective, safe, and a curative approach for endovascular treatment of complex TDCCFs and internal carotid artery reconstruction. ABBREVIATIONS: DB, detachable balloon EVT, endovascular treatment ICA, internal carotid artery n-BCA, N-butyl cyanoacrylate TDCCF, traumatic direct carotid-cavernous fistula (Source: Neurosurgery)
Source: Neurosurgery - December 1, 2016 Category: Neurosurgery Tags: Research-Human-Clinical Studies Source Type: research

Diffusion Tensor Imaging: A Possible Biomarker in Severe Traumatic Brain Injury and Aneurysmal Subarachnoid Hemorrhage?
CONCLUSION: DTI parameters, assessed at approximately day 12 after injury, correlated with mortality at 6 months in patients with severe TBI or aSAH. Similar patterns were found for both TBI and aSAH patients. This supports a potential role of DTI as early endpoint for clinical studies and a predictor of late mortality. ABBREVIATIONS: aSAH, aneurysmal subarachnoid hemorrhage DTI, diffusion tensor imaging FA, fractional anisotropy GOSE, Glasgow Outcome Scale Extended TBI, traumatic brain injury TE, echo time TR, repetition time (Source: Neurosurgery)
Source: Neurosurgery - December 1, 2016 Category: Neurosurgery Tags: Research-Human-Clinical Studies Source Type: research

Decompressive Surgery for Diabetic Neuropathy: Waiting for Incontrovertible Proof
Triple decompression surgery has been advocated as a treatment for diabetic peripheral neuropathy (DPN). A practice advisory published in 2006 by the American Academy of Neurology concluded that “this treatment alternative should be considered unproven.” Since then, multiple cohort studies involving several thousands of patients and 1 nonblind, randomized, controlled trial have been published, suggesting that surgical treatment of DPN has become commonplace in many centers globally. The results of these observational studies suggest that decompressive surgery could result in a substantial reduction of pain and ...
Source: Neurosurgery - December 1, 2016 Category: Neurosurgery Tags: Review Source Type: research

Should Levetiracetam or Phenytoin Be Used for Posttraumatic Seizure Prophylaxis? A Systematic Review of the Literature and Meta-analysis
CONCLUSION: The lack of evidence on which antiepileptic drug to use in PTS is surprising given the number of patients prescribed an antiepileptic drug therapy for TBI. On the basis of currently available Level III evidence, patients treated with either levetiracetam or phenytoin have similar incidences of early seizures after TBI. ABBREVIATIONS: ADE, adverse drug event AED, antiepileptic drug CI, confidence interval OR, odds ratio PTS, posttraumatic seizure TBI, traumatic brain injury (Source: Neurosurgery)
Source: Neurosurgery - December 1, 2016 Category: Neurosurgery Tags: Review Source Type: research

Directionality of Medial Prefrontal Cortex and Hippocampal Interactions Is Task-Dependent
No abstract available (Source: Neurosurgery)
Source: Neurosurgery - December 1, 2016 Category: Neurosurgery Tags: Science Times Source Type: research

Neuroregeneration: North America's First Human Stem Cell Trial for Stroke
No abstract available (Source: Neurosurgery)
Source: Neurosurgery - December 1, 2016 Category: Neurosurgery Tags: Science Times Source Type: research

Abnormal Cerebrospinal Fluid Flow: A New Model of Idiopathic Scoliosis
No abstract available (Source: Neurosurgery)
Source: Neurosurgery - December 1, 2016 Category: Neurosurgery Tags: Science Times Source Type: research

“Tag Team” Glioblastoma Therapy: Results From a Phase 1 Trial of Toca 511 and 5-Fluorocytosine for Recurrent High-Grade Glioma
No abstract available (Source: Neurosurgery)
Source: Neurosurgery - December 1, 2016 Category: Neurosurgery Tags: Science Times Source Type: research

A Randomized Clinical Trial of Aggressive Blood Pressure Control in Patients With Acute Cerebral Hemorrhage
No abstract available (Source: Neurosurgery)
Source: Neurosurgery - December 1, 2016 Category: Neurosurgery Tags: Science Times Source Type: research

Human Cerebral Cortex Map 2.0
No abstract available (Source: Neurosurgery)
Source: Neurosurgery - December 1, 2016 Category: Neurosurgery Tags: Science Times Source Type: research

IL-21 Receptor Modulates Ischemic Severity in Stroke
No abstract available (Source: Neurosurgery)
Source: Neurosurgery - December 1, 2016 Category: Neurosurgery Tags: Science Times Source Type: research

Long-term Training With a Brain-Machine Interface-Based Gait Protocol Induces Partial Neurological Recovery in Paraplegic Patients
No abstract available (Source: Neurosurgery)
Source: Neurosurgery - December 1, 2016 Category: Neurosurgery Tags: Science Times Source Type: research

Gross Total Resection of Glioblastoma Improves Overall Survival and Progression-Free Survival Compared to Subtotal Resection or Biopsy Alone
No abstract available (Source: Neurosurgery)
Source: Neurosurgery - December 1, 2016 Category: Neurosurgery Tags: Science Times Source Type: research

Focused Ultrasound Enhances Central Nervous System Delivery of Bevacizumab for Malignant Glioma Treatment
No abstract available (Source: Neurosurgery)
Source: Neurosurgery - December 1, 2016 Category: Neurosurgery Tags: Science Times Source Type: research

Next Month in Neurosurgery
No abstract available (Source: Neurosurgery)
Source: Neurosurgery - October 28, 2016 Category: Neurosurgery Tags: Departments Source Type: research

Table of Contents by Topic
No abstract available (Source: Neurosurgery)
Source: Neurosurgery - October 28, 2016 Category: Neurosurgery Tags: Departments Source Type: research

Calendar of Events
No abstract available (Source: Neurosurgery)
Source: Neurosurgery - October 28, 2016 Category: Neurosurgery Tags: Departments Source Type: research

Surfer’s Myelopathy: A Rare Form of Spinal Cord Infarction in Novice Surfers: A Systematic Review: Erratum
No abstract available (Source: Neurosurgery)
Source: Neurosurgery - October 28, 2016 Category: Neurosurgery Tags: Erratum Source Type: research

In Reply: High-Risk Factors in Symptomatic Patients Undergoing Carotid Artery Stenting With Distal Protection: Buffalo Risk Assessment Scale (BRASS)
No abstract available (Source: Neurosurgery)
Source: Neurosurgery - October 28, 2016 Category: Neurosurgery Tags: Correspondence Source Type: research

Letter: High-Risk Factors in Symptomatic Patients Undergoing Carotid Artery Stenting With Distal Protection: Buffalo Risk Assessment Scale (BRASS)
No abstract available (Source: Neurosurgery)
Source: Neurosurgery - October 28, 2016 Category: Neurosurgery Tags: Correspondence Source Type: research

Letter: Is Intracranial Pressure Monitoring of Patients With Diffuse Traumatic Brain Injury Valuable? An Observational Multicenter Study
No abstract available (Source: Neurosurgery)
Source: Neurosurgery - October 28, 2016 Category: Neurosurgery Tags: Correspondence Source Type: research

Book Review: Handbook of Bleeding and Coagulation for Neurosurgery
No abstract available (Source: Neurosurgery)
Source: Neurosurgery - October 28, 2016 Category: Neurosurgery Tags: Book Reviews Source Type: research