In-Stent Stenosis After Pipeline Embolization Device in Intracranial Aneurysms: Incidence, Predictors, and Clinical Outcomes
CONCLUSION: ISS occurs in approximately 10.03% of cases at a mean follow-up of 9 months. Statistically, current smoking history and cerebral atherosclerosis are the main predictors of ISS. Severe ISS may be associated with higher risk of neurological ischemic events in patients with IA after pipeline embolization device implantation. (Source: Neurosurgery)
Source: Neurosurgery - November 22, 2022 Category: Neurosurgery Tags: Research—Human—Clinical Studies: Endovascular Source Type: research

National Institutes of Health Stroke Scale Score Less Than 10 at 24 hours After Stroke Onset Is a Strong Predictor of a Favorable Outcome After Mechanical Thrombectomy
CONCLUSION: NIHSS score (Source: Neurosurgery)
Source: Neurosurgery - November 22, 2022 Category: Neurosurgery Tags: Research—Human—Clinical Studies: Endovascular Source Type: research

Development of Risk Stratification Predictive Models for Cervical Deformity Surgery
CONCLUSION: Revisions were predicted using a predominance of radiographic parameters while the occurrence of major complications relied on baseline bone health, radiographic, and surgical characteristics. (Source: Neurosurgery)
Source: Neurosurgery - November 22, 2022 Category: Neurosurgery Tags: Research—Human—Clinical Studies: Spine Source Type: research

Risk for Hemorrhage the First 2 Years After Gamma Knife Surgery for Arteriovenous Malformations: An Update
CONCLUSION: Large AVMs (>5 cm3) treated with low doses (≤16 Gy) had higher and small AVMs treated with high doses a lower risk for hemorrhage as compared with untreated AVMs. This was detectable within the first 6 months after GKS. No difference in hemorrhage rate could be detected for the other AVMs. Based on our findings, it is advisable to prescribe>16 Gy to larger AVMs, assuming that the risk for radiation-induced complications can be kept at an acceptable level. (Source: Neurosurgery)
Source: Neurosurgery - November 22, 2022 Category: Neurosurgery Tags: Research—Human—Clinical Studies: Cerebrovascular Source Type: research

First-Pass Effect Predicts Clinical Outcome and Infarct Growth After Thrombectomy for Distal Medium Vessel Occlusions
CONCLUSION: The mFPE may be associated with better clinical outcomes and lower stroke progression in DMVO. (Source: Neurosurgery)
Source: Neurosurgery - November 22, 2022 Category: Neurosurgery Tags: Research—Human—Clinical Studies: Endovascular Source Type: research

External Validation of the HATCH (Hemorrhage, Age, Treatment, Clinical State, Hydrocephalus) Score for Prediction of Functional Outcome After Subarachnoid Hemorrhage
CONCLUSION: This multicenter external validation analysis confirms the HATCH score to be a strong independent predictor for functional outcome. Its incorporation into daily practice may be of benefit for goal-directed patient care in aSAH. (Source: Neurosurgery)
Source: Neurosurgery - November 22, 2022 Category: Neurosurgery Tags: Research—Human—Clinical Studies: Cerebrovascular Source Type: research

Risk Factors for Fracture Nonunion and Transverse Atlantal Ligament Injury After Isolated Atlas Fractures: A Case Series of 97 Patients
CONCLUSION: LMD> 7 mm on CT is not sensitive for TAL injury. Some atlas fractures with TAL injury can be managed with a cervical collar. Nonunion rates are not different between halo immobilization and cervical collar, but a strong selection bias precludes directly comparing the efficacy of these modalities. Age independently predicts nonunion. (Source: Neurosurgery)
Source: Neurosurgery - November 22, 2022 Category: Neurosurgery Tags: Research—Human—Clinical Studies: Spine Source Type: research

Nationwide Readmission Rates and Hospital Charges for Patients With Surgical Evacuation of Nontraumatic Subdural Hematomas: Part 2—Burr Hole Craniostomy
CONCLUSION: These national trends in 30-day readmission rates after nontraumatic SDH evacuation by BHC not otherwise published provide quality benchmarks that can aid national quality improvement efforts. (Source: Neurosurgery)
Source: Neurosurgery - November 22, 2022 Category: Neurosurgery Tags: Research—Human—Clinical Studies: Cerebrovascular Source Type: research

Natural History of Brachial Plexus, Peripheral Nerve, and Spinal Schwannomas
BACKGROUND: Management of sporadic schwannomas is often dictated by a patient's clinical presentation and the tumor's behavior. For patients who are managed nonsurgically, there are little data available about the expected natural history. OBJECTIVE: To evaluate the natural history and growth patterns of extracranial schwannomas including tumors of the distal peripheral nerves, spine, and brachial plexus. METHODS: A retrospective review was performed to identify patients with nonsyndromic extracranial schwannomas at a single tertiary care institution diagnosed between 2002 and 2019. Patient data and tumor...
Source: Neurosurgery - November 22, 2022 Category: Neurosurgery Tags: Research—Human—Clinical Studies: Peripheral Nerve Source Type: research

Concurrent Administration of Immune Checkpoint Inhibitors and Stereotactic Radiosurgery Is Well-Tolerated in Patients With Melanoma Brain Metastases: An International Multicenter Study of 203 Patients
CONCLUSION: Concurrent administration of ICIs and SRS are not associated with an increased risk of RN. Tumors harboring BRAF mutation, or perhaps prior exposure to targeted agents, may increase this risk. Radiosurgical optimization to maintain V12 (Source: Neurosurgery)
Source: Neurosurgery - November 22, 2022 Category: Neurosurgery Tags: Research—Human—Clinical Studies: Radiation Oncology Source Type: research

Targeted Temperature Management for Severe Subarachnoid Hemorrhage Using Endovascular and Surface Cooling Systems: A Nonrandomized Interventional Study Using Historical Control
CONCLUSION: Endovascular TTM at 36 to 38 °C after surface cooling was feasible and safely performed in patients with severe SAH. Combined TTM for 2 weeks was associated with a lower incidence of vasospasm-related infarction and may improve outcomes. (Source: Neurosurgery)
Source: Neurosurgery - November 22, 2022 Category: Neurosurgery Tags: Research—Human—Clinical Studies: Cerebrovascular Source Type: research

Reverse End-to-Side Nerve Transfer for Severe Ulnar Nerve Injury: A Western Canadian Multicentre Prospective Nonrandomized Cohort Study
BACKGROUND: Reverse end-to-side (RETS) nerve transfer has become increasingly popular in patients with severe high ulnar nerve injury, but the reported outcomes have been inconsistent. OBJECTIVE: To evaluate the “babysitting effect,” we compared outcomes after anterior interosseous nerve RETS transfer with nerve decompression alone. To evaluate the source of regenerating axons, a group with end-to-end (ETE) transfer was used for comparisons. METHODS: Electrophysiology measures were used to quantify the regeneration of anterior interosseous nerve (AIN) and ulnar nerve fibers while functional recovery w...
Source: Neurosurgery - November 22, 2022 Category: Neurosurgery Tags: Research—Human—Clinical Trials: Peripheral Nerve Source Type: research

Management of Chronic Subdural Hematoma: A Systematic Review and Component Network Meta-analysis of 455 Studies With 103 645 Cases
CONCLUSION: Recurrence after evacuation occurs in approximately 10% of cSDHs, and the various surgical interventions are approximately equivalent. Corticosteroids are associated with reduced recurrence but also increased morbidity. Drains reduce the risk of recurrence, but the position of drain (subdural vs subgaleal) did not influence recurrence. Middle meningeal artery embolization is a promising treatment warranting further evaluation in randomized trials. (Source: Neurosurgery)
Source: Neurosurgery - November 22, 2022 Category: Neurosurgery Tags: Review: General Neurosurgery Source Type: research

A Systematic Review of Neuropsychological Outcomes After Treatment of Intracranial Aneurysms
CONCLUSION: The current available data and published studies demonstrate a trend toward improved neurocognitive and psychological outcomes after endovascular treatment. Although these findings should be considered when deciding on the optimal treatment method for each patient, drawing definitive conclusions is difficult because of heterogeneity between patients and studies. (Source: Neurosurgery)
Source: Neurosurgery - November 22, 2022 Category: Neurosurgery Tags: Review: Cerebrovascular Source Type: research

Neurostimulation for Functional Recovery After Traumatic Brain Injury: Current Evidence and Future Directions for Invasive Surgical Approaches
We aim to provide a comprehensive review of the current scientific evidence supporting the use of invasive neurostimulation in the treatment of deficits associated with traumatic brain injury (TBI), as well as to identify future directions for research and highlight important questions that remain unaddressed. Neurostimulation is a treatment modality with expanding applications in modern medical practice. Targeted electrical stimulation of specific brain regions has been shown to increase synaptogenesis and enhance structural reorganization of neuronal networks. This underlying therapeutic effect might be of high value for...
Source: Neurosurgery - November 22, 2022 Category: Neurosurgery Tags: Review: Stereotactic Functional Source Type: research