Commentary: The Association of Language Barriers With Process Outcomes After Craniotomy for Brain Tumor
No abstract available (Source: Neurosurgery)
Source: Neurosurgery - October 20, 2022 Category: Neurosurgery Tags: Commentary: Socioeconomics, Health Policy and Law Source Type: research

Book Review: Perioperative Neuroscience: Translational Research
No abstract available (Source: Neurosurgery)
Source: Neurosurgery - October 20, 2022 Category: Neurosurgery Tags: Book Review: Neuroscience Source Type: research

Commentary: Intellectual Property Protection in Neurosurgery: An Overview
No abstract available (Source: Neurosurgery)
Source: Neurosurgery - October 20, 2022 Category: Neurosurgery Tags: Commentary: Socioeconomics, Health Policy and Law Source Type: research

The Impact of Frailty on Traumatic Brain Injury Outcomes: An Analysis of 691 821 Nationwide Cases
BACKGROUND: Frailty, a decline in physiological reserve, prognosticates poorer outcomes for several neurosurgical conditions. However, the impact of frailty on traumatic brain injury outcomes is not well characterized. OBJECTIVE: To analyze the association between frailty and traumatic intracranial hemorrhage (tICH) outcomes in a nationwide cohort. METHODS: We identified all adult admissions for tICH in the National Trauma Data Bank from 2007 to 2017. Frailty was quantified using the validated modified 5-item Frailty Index (mFI-5) metric (range = 0-5), with mFI-5 ≥2 denoting frailty. Analyzed outcomes i...
Source: Neurosurgery - October 20, 2022 Category: Neurosurgery Tags: Research—Human—Clinical Studies: Neurotrauma Source Type: research

Automated Detection and Surgical Planning for Focal Cortical Dysplasia with Multicenter Validation
BACKGROUND: In patients with surgically amenable focal cortical dysplasia (FCD), subtle neuroimaging representation and the risk of open surgery lead to gaps in surgical treatment and delays in surgery. OBJECTIVE: To construct an integrated platform that can accurately detect FCD and automatically establish trajectory planning for magnetic resonance–guided laser interstitial thermal therapy. METHODS: This multicenter study included retrospective patients to train the automated detection model, prospective patients for model evaluation, and an additional cohort for construction of the automated trajector...
Source: Neurosurgery - October 20, 2022 Category: Neurosurgery Tags: Research—Human—Clinical Studies: Stereotactic Functional Source Type: research

Serum Levels of Myo-inositol Predicts Clinical Outcome 1 Year After Aneurysmal Subarachnoid Hemorrhage
BACKGROUND: Early prognostication of long-term outcome in patients suffering from spontaneous subarachnoid hemorrhage (SAH) remains a challenge. No biomarkers are routinely used for prognostication. A previous study has indicated that the metabolite myo-inositol (MI) may be used to predict long-term outcome. OBJECTIVE: To investigate if MI measured in serum correlates with long-term clinical outcome in patients suffering from SAH. METHODS: We conducted an observational cohort study including 88 patients treated for SAH at Umeå University Hospital. Serum samples were collected in the hospital, and a gas c...
Source: Neurosurgery - October 20, 2022 Category: Neurosurgery Tags: Research—Human—Clinical Studies: Cerebrovascular Source Type: research

Angioarchitectural Analysis of Arteriovenous Shunts in Dural Arteriovenous Fistulas and Its Clinical Implications
CONCLUSION: The 4 shunt patterns of DAVFs demonstrate distinct characteristics for the fistula, sinus and cortical vein connection. Meticulous analysis of the angioarchitectural characteristics and clinical implications is warranted for safe and effective treatment. (Source: Neurosurgery)
Source: Neurosurgery - October 20, 2022 Category: Neurosurgery Tags: Research—Human—Clinical Studies: Endovascular Source Type: research

Resection of the Cavernous Sinus Medial Wall Improves Remission Rate in Functioning Pituitary Tumors: Retrospective Analysis of 248 Consecutive Cases
CONCLUSION: MWCS invasion occurred in 57% of cases confirmed histologically where it was unclear during surgery, and its resection can improve the overall complete remission rate in FPT cases. (Source: Neurosurgery)
Source: Neurosurgery - October 20, 2022 Category: Neurosurgery Tags: Research—Human—Clinical Studies: Tumor Source Type: research

Comparison of Fusion versus Nonunion After 4-Level and 5-Level Anterior Cervical Diskectomy and Fusion With Anterior Plate Fixation
BACKGROUND: Nonunion remains a concern in multilevel anterior cervical discectomy and fusion (ACDF), yet there are limited data on nonunion after 4 to 5-level ACDF. In fact, the largest series on 4-level or 5-level ACDF focused specifically on the swallowing outcomes. OBJECTIVE: To assess nonunion after 4 to 5-level ACDF. METHODS: Forty-one patients treated with 4 to 5-level ACDF with minimum of 12-month radiographic follow-up were retrospectively reviewed. Nonunion was found in 25 patients (61%) and 42 levels (25%) and complete fusion in 16 (39%) patients and 126 levels (75%). The 2 groups were further c...
Source: Neurosurgery - October 20, 2022 Category: Neurosurgery Tags: Research—Human—Clinical Studies: Spine Source Type: research

Factors Affecting Stiffness-Related Functional Disability After Long Segmental Fusion for Adult Spinal Deformity
CONCLUSION: This study showed that female sex, higher American Society of Anesthesiology grades, and longer fusion length influenced SRFD after long segmental fusion for ASD. Sagittal parameters related to the degree of deformity correction did not significantly affect SRFD. (Source: Neurosurgery)
Source: Neurosurgery - October 20, 2022 Category: Neurosurgery Tags: Research—Human—Clinical Studies: Spine Source Type: research

Endovascular Therapy for Cerebral Vein Thrombosis: A Propensity-Matched Analysis of Anticoagulation in the Treatment of Cerebral Venous Thrombosis
CONCLUSION: In this large observational cohort, there was no evidence of benefit with EVT for CVT. These findings corroborate the results from the TO-ACT trial. (Source: Neurosurgery)
Source: Neurosurgery - October 20, 2022 Category: Neurosurgery Tags: Research—Human—Clinical Studies: Endovascular Source Type: research

Early Diagnosis and Surgical Intervention Within 3 Weeks From Symptom Onset Are Associated With Prolonged Survival of Patients With Glioblastoma
CONCLUSION: Early diagnosis within 2 weeks and surgical interventions within 3 weeks from the symptom onset are associated with prolonged patient survival. Early GBM treatment will benefit patients with GBM. (Source: Neurosurgery)
Source: Neurosurgery - October 20, 2022 Category: Neurosurgery Tags: Research—Human—Clinical Studies: Tumor Source Type: research

Venous Sinus Stenting for Low Pressure Gradient Stenoses in Idiopathic Intracranial Hypertension
CONCLUSION: Patients with IH with low venous pressure gradient venous sinus stenosis seem to benefit equally from venous stenting compared with their higher gradient counterparts. Re-evaluation of our restrictive criteria for this potentially vision sparing intervention is warranted. Future prospective confirmatory studies are needed. (Source: Neurosurgery)
Source: Neurosurgery - October 20, 2022 Category: Neurosurgery Tags: Research—Human—Clinical Studies: Endovascular Source Type: research

Long-Term Outcomes of Bilateral Subthalamic Nucleus Deep Brain Stimulation for Patients With Parkinson's Disease: 10 Years and Beyond
CONCLUSION: STN DBS is a safe and effective treatment for patients with advanced PD. This study based on the long-term follow-up of large patient populations can be used to elucidate the long-term fate of patients who underwent bilateral STN DBS for PD. (Source: Neurosurgery)
Source: Neurosurgery - October 20, 2022 Category: Neurosurgery Tags: Research—Human—Clinical Studies: Stereotactic Functional Source Type: research

Targeting Accuracy and Clinical Outcomes of Awake versus Asleep Interventional Magnetic Resonance Imaging-Guided Deep Brain Stimulation for Parkinson's Disease: The University of California, San Francisco Experience
BACKGROUND: Interventional MRI (iMRI)-guided implantation of deep brain stimulator (DBS) leads has been developed to treat patients with Parkinson's disease (PD) without the need for awake testing. OBJECTIVE: Direct comparisons of targeting accuracy and clinical outcomes for awake stereotactic with asleep iMRI-DBS for PD are limited. METHODS: We performed a retrospective review of patients with PD who underwent awake or iMRI-guided DBS surgery targeting the subthalamic nucleus or globus pallidus interna between 2013 and 2019 at our institution. Outcome measures included Unified Parkinson's Disease Rating ...
Source: Neurosurgery - October 20, 2022 Category: Neurosurgery Tags: Research—Human—Clinical Studies: Stereotactic Functional Source Type: research