Deep Neural Networks Can Accurately Detect Blood Loss and Hemorrhage Control Task Success From Video
CONCLUSION:
BL and task outcome classification are important components of an automated assessment of surgical performance. DNNs can predict BL and outcome of hemorrhage control from video alone; their performance is improved with surgical instrument presence data. The generalizability of DNNs trained on hemorrhage control tasks should be investigated. (Source: Neurosurgery)
Source: Neurosurgery - May 25, 2022 Category: Neurosurgery Tags: Research—Laboratory: Tumor Source Type: research
Body Mass Index and the Risk of Poor Outcome in Surgically Treated Patients With Good-Grade Aneurysmal Subarachnoid Hemorrhage
CONCLUSION:
Because higher BMI values seem to associate with poor outcomes in surgically treated patients with good-grade aSAH, it seems unlikely that obesity protects patients with aSAH from poor outcomes. (Source: Neurosurgery)
Source: Neurosurgery - May 25, 2022 Category: Neurosurgery Tags: Research—Human—Clinical Studies: Cerebrovascular Source Type: research
Malignant Pineal Parenchymal Tumors in Adults: A National Cancer Database Analysis
BACKGROUND:
Limited retrospective data exist on malignant pineal parenchymal tumors (PPTs) in adults, and there are no large previous studies that review clinical outcomes across the 3 treatment arms of surgery, radiotherapy, and chemotherapy. As a result, optimal disease management has yet to be defined.
OBJECTIVE:
To evaluate treatment trends and perform survival analysis in adult PPT.
METHODS:
The National Cancer Database was queried for histologically confirmed PPT diagnosed from 2007 to 2016. Univariate and multivariate Cox regressions were used to evaluate the prognostic impact of covariates. Kaplan...
Source: Neurosurgery - May 25, 2022 Category: Neurosurgery Tags: Research—Human—Clinical Studies: Tumor Source Type: research
A Data-Driven Approach to Predicting 5-Aminolevulinic Acid–Induced Fluorescence and World Health Organization Grade in Newly Diagnosed Diffuse Gliomas
CONCLUSION:
We demonstrate a strong correlation between enhancement on preoperative MRI and the likelihood of visible fluorescence during surgery in patients with intermediate-grade glioma. Our analysis provides a robust method for predicting 5-ALA–induced fluorescence in patients with grade II and grade III gliomas. (Source: Neurosurgery)
Source: Neurosurgery - May 25, 2022 Category: Neurosurgery Tags: Research—Human—Clinical Studies: Tumor Source Type: research
Multiple Meningiomas as a Criterion for the Diagnosis of Neurofibromatosis Type 2 and Other Tumor Predisposition Syndromes
CONCLUSION:
Patients presenting with UVS and MM are significantly more likely to have a nonrefuted diagnosis of NF2 than patients presenting with UVS and ≥2 NIDS, but significantly less likely to develop bilateral VS. Seven percent of those presenting with MM without meeting NF2 criteria had PV in SMARCE1, and 5% had mosaic NF2. (Source: Neurosurgery)
Source: Neurosurgery - May 25, 2022 Category: Neurosurgery Tags: Research—Human—Clinical Studies: Skull Base Source Type: research
Long-Term Risks of Hemorrhage and Adverse Radiation Effects of Stereotactic Radiosurgery for Brain Arteriovenous Malformations
CONCLUSION:
GKS is associated with reduced hemorrhage risk and high nidus obliteration rates in patients with AVM. The incidence of late AREs tended to increase over time. The most common ARE was CF/CEH, which can be safely removed; however, careful attention should be paid to the long-term development of fatal radiation-induced tumors. (Source: Neurosurgery)
Source: Neurosurgery - May 25, 2022 Category: Neurosurgery Tags: Research—Human—Clinical Studies: Cerebrovascular Source Type: research
Dural Invasion as a Marker of Aggressive Pituitary Adenomas
CONCLUSION:
Dural invasion is associated with larger tumors, suprasellar and sphenoid sinus invasion, and pituitary failure but is not predictive of a more aggressive postoperative course. Routine dural biopsy is therefore of limited benefit in predicting postoperative recurrences. Cofilin expression may be an adjunctive biomarker of invasion in recurrent tumors, but MMP9 expression does not predict tumor behavior. (Source: Neurosurgery)
Source: Neurosurgery - May 25, 2022 Category: Neurosurgery Tags: Research—Human—Clinical Studies: Tumor Source Type: research
Machine Learning for Predicting Discharge Disposition After Traumatic Brain Injury
CONCLUSION:
Our group presents high-performing ML models to predict trichotomized discharge disposition. These models can assist in optimization of patient triage and treatment, especially in cases of mild and moderate TBI. (Source: Neurosurgery)
Source: Neurosurgery - May 25, 2022 Category: Neurosurgery Tags: Research—Human—Clinical Studies: Neurotrauma Source Type: research
Rapid Automated Analysis of Skull Base Tumor Specimens Using Intraoperative Optical Imaging and Artificial Intelligence
BACKGROUND:
Accurate specimen analysis of skull base tumors is essential for providing personalized surgical treatment strategies. Intraoperative specimen interpretation can be challenging because of the wide range of skull base pathologies and lack of intraoperative pathology resources.
OBJECTIVE:
To develop an independent and parallel intraoperative workflow that can provide rapid and accurate skull base tumor specimen analysis using label-free optical imaging and artificial intelligence.
METHODS:
We used a fiber laser–based, label-free, nonconsumptive, high-resolution microscopy method ( (Source: Neurosurgery)
Source: Neurosurgery - May 25, 2022 Category: Neurosurgery Tags: Research—Human—Clinical Studies: Tumor Source Type: research
Stereotactic Radiosurgery Compared With Active Surveillance for Asymptomatic, Parafalcine, and Parasagittal Meningiomas: A Matched Cohort Analysis From the IMPASSE Study
BACKGROUND:
The optimal management of asymptomatic, presumed WHO grade I meningiomas remains controversial.
OBJECTIVE:
To define the safety and efficacy of stereotactic radiosurgery (SRS) compared with active surveillance for the management of patients with asymptomatic parafalcine/parasagittal (PFPS) meningiomas.
METHODS:
Data from SRS-treated patients from 14 centers and patients managed conservatively for an asymptomatic, PFPS meningioma were compared. Local tumor control rate and new neurological deficits development were evaluated in the active surveillance and the SRS-treated cohorts.
RESULTS:
...
Source: Neurosurgery - May 25, 2022 Category: Neurosurgery Tags: Research—Human—Clinical Studies: Tumor Source Type: research
Spine Stereotactic Body Radiotherapy for Prostate Cancer Metastases and the Impact of Hormone Sensitivity Status on Local Control
CONCLUSION:
Favorable LC rates were observed after spine SBRT for PCa metastases; strategies to improve long-term LC in patients with CRPC require further investigation. (Source: Neurosurgery)
Source: Neurosurgery - May 25, 2022 Category: Neurosurgery Tags: Research—Human—Clinical Studies: Spine Source Type: research
Influence of Time of Discharge and Length of Stay on 30-Day Outcomes After Elective Anterior Cervical Spine Surgery
CONCLUSION:
There does not appear to be an association between readmission or return to the emergency department and early TOD after elective spine surgery. Overuse of inpatient physical and occupational therapy consultations may contribute to decreased patient throughput in surgical admissions. (Source: Neurosurgery)
Source: Neurosurgery - May 25, 2022 Category: Neurosurgery Tags: Research—Human—Clinical Studies: Socioeconomics, Health Policy and Law Source Type: research
Characteristics of a COVID-19 Cohort With Large Vessel Occlusion: A Multicenter International Study
BACKGROUND:
The mechanisms and outcomes in coronavirus disease (COVID-19)–associated stroke are unique from those of non–COVID-19 stroke.
OBJECTIVE:
To describe the efficacy and outcomes of acute revascularization of large vessel occlusion (LVO) in the setting of COVID-19 in an international cohort.
METHODS:
We conducted an international multicenter retrospective study of consecutively admitted patients with COVID-19 with concomitant acute LVO across 50 comprehensive stroke centers. Our control group constituted historical controls of patients presenting with LVO and receiving a mechanical thrombectom...
Source: Neurosurgery - May 25, 2022 Category: Neurosurgery Tags: Research—Human—Clinical Studies: Endovascular Source Type: research
Clopidogrel Bolus is Inferior to Sustained Clopidogrel Pretreatment in Patients Undergoing Carotid Artery Stent Placement
BACKGROUND:
Clopidogrel bolus is an option used before carotid artery stent (CAS) placement when sustained clopidogrel pretreatment is not used.
OBJECTIVE:
To compare the effect of clopidogrel bolus (450 mg administered ≥4 hours) with sustained clopidogrel pretreatment (48 hours or greater) before CAS among patients recruited in the Carotid Revascularization Endarterectomy versus Stenting Trial.
METHODS:
We compared the rates of primary end point (either any stroke, myocardial infarction, or death during the periprocedural period or any ipsilateral stroke within 4 years) between patients who received cl...
Source: Neurosurgery - May 25, 2022 Category: Neurosurgery Tags: Research—Human—Clinical Studies: Endovascular Source Type: research
Comparative Therapeutic Effectiveness of Anticoagulation and Conservative Management in Traumatic Cerebral Venous Sinus Thrombosis
CONCLUSION:
Treatment with AC for tCVST due to blunt head trauma may promote higher rates of complete thrombus recanalization when compared with conservative management. (Source: Neurosurgery)
Source: Neurosurgery - May 25, 2022 Category: Neurosurgery Tags: Research—Human—Clinical Studies: Neurotrauma Source Type: research
