Safety and Efficacy of the Off-Label Use of Pipeline Embolization Device Based on the 2018 Food and Drug Administration-Approved Indications for Intracranial Aneurysms: A Single-Center Retrospective Cohort Study
BACKGROUND:
The pipeline embolization device (PED; ev3/Covidien) has proven safe and effective for treating selected intracranial aneurysms. This device's versatility and popularity have driven increased interest in expanding the latest 2018 Food and Drug Administration–approved indications.
OBJECTIVE:
To compare “off-label” and “on-label” PED treatment.
METHODS:
Retrospective analysis of aneurysms treated with PED at a single center from 2013 to 2019. Comparisons were made based on the 2018 Food and Drug Administration–approved indications.
RESULTS:
A total of 492 treated aneurysms wer...
Source: Neurosurgery - May 25, 2022 Category: Neurosurgery Tags: Research—Human—Clinical Studies: Cerebrovascular Source Type: research
Measures of Intracranial Injury Size Do Not Improve Clinical Decision Making for Children With Mild Traumatic Brain Injuries and Intracranial Injuries
BACKGROUND:
When evaluating children with mild traumatic brain injuries (mTBIs) and intracranial injuries (ICIs), neurosurgeons intuitively consider injury size. However, the extent to which such measures (eg, hematoma size) improve risk prediction compared with the kids intracranial injury decision support tool for traumatic brain injury (KIIDS-TBI) model, which only includes the presence/absence of imaging findings, remains unknown.
OBJECTIVE:
To determine the extent to which measures of injury size improve risk prediction for children with mild traumatic brain injuries and ICIs.
METHODS:
We included ch...
Source: Neurosurgery - May 25, 2022 Category: Neurosurgery Tags: Research—Human—Clinical Studies: Pediatrics Source Type: research
Time to Steroid Independence After Laser Interstitial Thermal Therapy vs Medical Management for Treatment of Biopsy-Proven Radiation Necrosis Secondary to Stereotactic Radiosurgery for Brain Metastasis
BACKGROUND:
Radiation necrosis (RN) after stereotactic radiosurgery (SRS) for brain metastases (BM) can result in significant morbidity, compounded by the effects of extended steroid therapy. Laser interstitial thermal therapy (LITT) is a minimally invasive procedure that can offer definitive treatment for RN while potentially obviating the need for prolonged steroid use.
OBJECTIVE:
To compare LITT vs medical management (MM) in the treatment of RN.
METHODS:
A multicenter, retrospective study was performed of SRS-treated patients with BM who developed biopsy-proven RN and were treated with LITT or MM. Clin...
Source: Neurosurgery - May 25, 2022 Category: Neurosurgery Tags: Research—Human—Clinical Studies: Radiation Oncology Source Type: research
Angiographic, Cerebral Hemodynamic, and Cognitive Outcomes of Indirect Revascularization Surgery Alone for Adult Patients With Misery Perfusion due to Ischemic Moyamoya Disease
BACKGROUND:
Revascularization surgery for adult patients with ischemic moyamoya disease (MMD) may improve both cognitive function and cerebral perfusion.
OBJECTIVE:
To determine angiographic, cerebral hemodynamic, and cognitive outcomes of indirect revascularization surgery alone for adult patients with misery perfusion due to ischemic MMD (IDR group) and to test the superiority of indirect revascularization surgery for cognitive improvement by conducting comparisons with historical control patients who had undergone direct revascularization surgery (DR group) through prospective cohort study with historical con...
Source: Neurosurgery - May 25, 2022 Category: Neurosurgery Tags: Research—Human—Clinical Studies: Cerebrovascular Source Type: research
Acute Implantation of a Bioresorbable Polymer Scaffold in Patients With Complete Thoracic Spinal Cord Injury: 24-Month Follow-up From the INSPIRE Study
CONCLUSION
In this small group of patients with complete thoracic SCI, acute NSS implantation within the spinal cord appeared to be safe with no long-term neurological issues identified during the 24-month follow-up. Patients remain stable, with additional AIS conversions observed in some patients at 12 months and beyond. These data further support the safety and probable benefit of NSS implantation in this patient population. (Source: Neurosurgery)
Source: Neurosurgery - May 25, 2022 Category: Neurosurgery Tags: Research—Human—Clinical Trials: Spine Source Type: research
Thoracic Outlet Syndrome Part I: Systematic Review of the Literature and Consensus on Anatomy, Diagnosis, and Classification of Thoracic Outlet Syndrome by the European Association of Neurosurgical Societies' Section of Peripheral Nerve Surgery
CONCLUSION:
Because of the lack of level 1 evidence, consensus statements on anatomy, diagnosis, and classification of TOS from experts of the section of peripheral nerve surgery of the European Association of Neurosurgical Societies were developed with the Delphi method. Further work on reporting standards, prospective data collections, therapy, and long-term outcome is necessary. (Source: Neurosurgery)
Source: Neurosurgery - May 25, 2022 Category: Neurosurgery Tags: Review: Peripheral Nerve Source Type: research
Congress of Neurological Surgeons Systematic Review and Evidence-Based Guidelines on the Management of Progressive Glioblastoma in Adults: Update of the 2014 Guidelines
CONCLUSION:
Recent published literature provides new recommendations for the diagnosis and treatment of pGBM. The Central Nervous System Guidelines Committee will continue to pursue timely updates to further improve the care of patients with diagnosis.
https://www.cns.org/guidelines/browse-guidelines-detail/guidelines-management-of-progressive-glioblastoma (Source: Neurosurgery)
Source: Neurosurgery - May 25, 2022 Category: Neurosurgery Tags: CNS Progressive Glioblastoma Guideline Update: Tumor Source Type: research
In Reply: Fluorescence Guidance and Intraoperative Adjuvants to Maximize Extent of Resection
No abstract available (Source: Neurosurgery)
Source: Neurosurgery - April 25, 2022 Category: Neurosurgery Tags: CORRESPONDENCE: Tumor Source Type: research
Letter: Fluorescence Guidance and Intraoperative Adjuvants to Maximize Extent of Resection
No abstract available (Source: Neurosurgery)
Source: Neurosurgery - April 25, 2022 Category: Neurosurgery Tags: CORRESPONDENCE: General Neurosurgery Source Type: research
Letter: The Brown Student Neurosurgery & Neurology Research Conference: A Model for Student-Centric Neurosurgical Research Dissemination in the Virtual Conference Era
No abstract available (Source: Neurosurgery)
Source: Neurosurgery - April 25, 2022 Category: Neurosurgery Tags: CORRESPONDENCE: General Neurosurgery Source Type: research
In Reply: Pearls for Interpreting Neurosurgical Systematic Reviews and Meta-analyses: Lessons From a Collaborative Effort
No abstract available (Source: Neurosurgery)
Source: Neurosurgery - April 25, 2022 Category: Neurosurgery Tags: CORRESPONDENCE: Evidence-based Medicine Source Type: research
Letter: Pearls for Interpreting Neurosurgical Systematic Reviews and Meta-analyses: Lessons From a Collaborative Effort
No abstract available (Source: Neurosurgery)
Source: Neurosurgery - April 25, 2022 Category: Neurosurgery Tags: CORRESPONDENCE: Evidence-based Medicine Source Type: research
Letter: Unforeseen Hurdles Associated With Magnetic Resonance Imaging in Patients With Deep Brain Stimulation Devices
No abstract available (Source: Neurosurgery)
Source: Neurosurgery - April 25, 2022 Category: Neurosurgery Tags: Correspondence: Neuroradiology Source Type: research
Commentary: The Legal and Socioeconomic Considerations in Spine Telemedicine
No abstract available (Source: Neurosurgery)
Source: Neurosurgery - April 25, 2022 Category: Neurosurgery Tags: Commentary: Socioeconomics, Health Policy and Law Source Type: research
