Modafinil attenuates the neuroinflammatory response after experimental traumatic brain injury
This study aimed to explore if Modafinil can attenuate the neuroinflammatory phase of TBI and clarify the possible underlying mechanisms.METHODS: A weight drop model was used to induce experimental TBI on 30 Wistar albino rats. The treatment group received Modafinil on the day of the trauma and the following 5 days. Garcia Test was used to assess for neurological status and histopathological examination along with biochemical analysis of NSE, S-100B, CASP3, and TBARS levels were performed.RESULTS: Rats treated with Modafinil after the trauma had a statistically significant higher Garcia test score (p
Source: Journal of Neurosurgical Sciences - September 21, 2021 Category: Neurosurgery Authors: Yasar Ozturk Ismail Bozkurt Yahya Guvenc Umit Kepoglu Mehmet Cingirt Ozlem Gulbahar Tugba Ozcerezci Salim Senturk Mesut E Yaman Source Type: research

An early analysis of Codman ® CerebroFlo® Endexo coated ventricular catheters in the setting of intraventricular hemorrhage
CONCLUSIONS: the CerebroFlo® catheter is a novel and effective tool in the management of IVH that should be widely considered for the management of IVH.PMID:34545731 | DOI:10.23736/S0390-5616.21.05421-7 (Source: Journal of Neurosurgical Sciences)
Source: Journal of Neurosurgical Sciences - September 21, 2021 Category: Neurosurgery Authors: Brian Fiani Ryan Jarrah Source Type: research

Brain low-grade gliomas with high-grade spinal localization. Report of a clinical case and systematic literature review
CONCLUSIONS: Spinal metastasis of intracranial LGGs is an adverse prognostic factor. Surgical violation of ventricles can play a role in the pathophysiology of CSF spread of tumor cells in LGGs.PMID:34545732 | DOI:10.23736/S0390-5616.21.05446-1 (Source: Journal of Neurosurgical Sciences)
Source: Journal of Neurosurgical Sciences - September 21, 2021 Category: Neurosurgery Authors: Francesca Battista Giovanni Muscas Silvia Scoccianti Anna Maria Buccoliero Davide Gadda Alessandro Della Puppa Source Type: research

Quantitative analysis of exposure and surgical maneuverability of three purely endoscopic keyhole approaches to the floor of the third ventricle
The objective of the study is to quantitatively assess and compare the exposure and microsurgical maneuverability of three absolutely endoscopic keyhole approaches, including interhemispheric transcallosal transchoroidal (TCTC), frontal transforminal transchoroidal (TFTC) and supraorbital subfrontal translamina terminalis (SFTL) approaches.METHODS: Anatomical dissections and exposure of the important structures of the third ventricle were performed using six formalin-fixed cadaveric human heads (twelve sides) under endoscope. Tubular retractor system was used in the TFTC approach. Quantitative anatomical relationship betwe...
Source: Journal of Neurosurgical Sciences - September 21, 2021 Category: Neurosurgery Authors: Changfu Zhang Zhengcun Yan Xiaodong Wang Yuping Li Hengzhu Zhang Source Type: research

Intraoperative MR Imaging in epilepsy surgery: systematic review of the literature and meta-analysis
CONCLUSIONS: This work presents the first meta-analysis of the value of iopMRI in epilepsy surgery. Its use resulted in an improvement of the desired extent of resection and led to a better seizure outcome compared to conventional surgery. Understanding its benefits might help improve surgical strategies in traditional, open epilepsy surgery.PMID:34545734 | DOI:10.23736/S0390-5616.21.05460-6 (Source: Journal of Neurosurgical Sciences)
Source: Journal of Neurosurgical Sciences - September 21, 2021 Category: Neurosurgery Authors: Matthias Tomschik Julia Shawarba Petra A Mercea Christian Dorfer Karl R össler Source Type: research

Artificial intelligence-enhanced intraoperative neurosurgical workflow: state of the art and future perspectives
CONCLUSIONS: In this review, we summarize the state-of-art applications of AI for the intraoperative augmentation of neurosurgical workflows across multiple subspecialties. ML models may boost surgical team performances by reducing human errors and providing patient-tailored surgical plans, but further and higher-quality studies need to be conducted.PMID:34545735 | DOI:10.23736/S0390-5616.21.05483-7 (Source: Journal of Neurosurgical Sciences)
Source: Journal of Neurosurgical Sciences - September 21, 2021 Category: Neurosurgery Authors: Leonardo Tariciotti Paolo Palmisciano Martina Giordano Giulia Remoli Eleonora Lacorte Giulio Bertani Marco Locatelli Francesco Dimeco Valerio M Caccavella Francesco Prada Source Type: research

Modafinil attenuates the neuroinflammatory response after experimental traumatic brain injury
This study aimed to explore if Modafinil can attenuate the neuroinflammatory phase of TBI and clarify the possible underlying mechanisms.METHODS: A weight drop model was used to induce experimental TBI on 30 Wistar albino rats. The treatment group received Modafinil on the day of the trauma and the following 5 days. Garcia Test was used to assess for neurological status and histopathological examination along with biochemical analysis of NSE, S-100B, CASP3, and TBARS levels were performed.RESULTS: Rats treated with Modafinil after the trauma had a statistically significant higher Garcia test score (p
Source: Journal of Neurosurgical Sciences - September 21, 2021 Category: Neurosurgery Authors: Yasar Ozturk Ismail Bozkurt Yahya Guvenc Umit Kepoglu Mehmet Cingirt Ozlem Gulbahar Tugba Ozcerezci Salim Senturk Mesut E Yaman Source Type: research

An early analysis of Codman ® CerebroFlo® Endexo coated ventricular catheters in the setting of intraventricular hemorrhage
CONCLUSIONS: the CerebroFlo® catheter is a novel and effective tool in the management of IVH that should be widely considered for the management of IVH.PMID:34545731 | DOI:10.23736/S0390-5616.21.05421-7 (Source: Journal of Neurosurgical Sciences)
Source: Journal of Neurosurgical Sciences - September 21, 2021 Category: Neurosurgery Authors: Brian Fiani Ryan Jarrah Source Type: research

Brain low-grade gliomas with high-grade spinal localization. Report of a clinical case and systematic literature review
CONCLUSIONS: Spinal metastasis of intracranial LGGs is an adverse prognostic factor. Surgical violation of ventricles can play a role in the pathophysiology of CSF spread of tumor cells in LGGs.PMID:34545732 | DOI:10.23736/S0390-5616.21.05446-1 (Source: Journal of Neurosurgical Sciences)
Source: Journal of Neurosurgical Sciences - September 21, 2021 Category: Neurosurgery Authors: Francesca Battista Giovanni Muscas Silvia Scoccianti Anna Maria Buccoliero Davide Gadda Alessandro Della Puppa Source Type: research

Quantitative analysis of exposure and surgical maneuverability of three purely endoscopic keyhole approaches to the floor of the third ventricle
The objective of the study is to quantitatively assess and compare the exposure and microsurgical maneuverability of three absolutely endoscopic keyhole approaches, including interhemispheric transcallosal transchoroidal (TCTC), frontal transforminal transchoroidal (TFTC) and supraorbital subfrontal translamina terminalis (SFTL) approaches.METHODS: Anatomical dissections and exposure of the important structures of the third ventricle were performed using six formalin-fixed cadaveric human heads (twelve sides) under endoscope. Tubular retractor system was used in the TFTC approach. Quantitative anatomical relationship betwe...
Source: Journal of Neurosurgical Sciences - September 21, 2021 Category: Neurosurgery Authors: Changfu Zhang Zhengcun Yan Xiaodong Wang Yuping Li Hengzhu Zhang Source Type: research

Intraoperative MR Imaging in epilepsy surgery: systematic review of the literature and meta-analysis
CONCLUSIONS: This work presents the first meta-analysis of the value of iopMRI in epilepsy surgery. Its use resulted in an improvement of the desired extent of resection and led to a better seizure outcome compared to conventional surgery. Understanding its benefits might help improve surgical strategies in traditional, open epilepsy surgery.PMID:34545734 | DOI:10.23736/S0390-5616.21.05460-6 (Source: Journal of Neurosurgical Sciences)
Source: Journal of Neurosurgical Sciences - September 21, 2021 Category: Neurosurgery Authors: Matthias Tomschik Julia Shawarba Petra A Mercea Christian Dorfer Karl R össler Source Type: research

Artificial intelligence-enhanced intraoperative neurosurgical workflow: state of the art and future perspectives
CONCLUSIONS: In this review, we summarize the state-of-art applications of AI for the intraoperative augmentation of neurosurgical workflows across multiple subspecialties. ML models may boost surgical team performances by reducing human errors and providing patient-tailored surgical plans, but further and higher-quality studies need to be conducted.PMID:34545735 | DOI:10.23736/S0390-5616.21.05483-7 (Source: Journal of Neurosurgical Sciences)
Source: Journal of Neurosurgical Sciences - September 21, 2021 Category: Neurosurgery Authors: Leonardo Tariciotti Paolo Palmisciano Martina Giordano Giulia Remoli Eleonora Lacorte Giulio Bertani Marco Locatelli Francesco Dimeco Valerio M Caccavella Francesco Prada Source Type: research

Modafinil attenuates the neuroinflammatory response after experimental traumatic brain injury
This study aimed to explore if Modafinil can attenuate the neuroinflammatory phase of TBI and clarify the possible underlying mechanisms.METHODS: A weight drop model was used to induce experimental TBI on 30 Wistar albino rats. The treatment group received Modafinil on the day of the trauma and the following 5 days. Garcia Test was used to assess for neurological status and histopathological examination along with biochemical analysis of NSE, S-100B, CASP3, and TBARS levels were performed.RESULTS: Rats treated with Modafinil after the trauma had a statistically significant higher Garcia test score (p
Source: Journal of Neurosurgical Sciences - September 21, 2021 Category: Neurosurgery Authors: Yasar Ozturk Ismail Bozkurt Yahya Guvenc Umit Kepoglu Mehmet Cingirt Ozlem Gulbahar Tugba Ozcerezci Salim Senturk Mesut E Yaman Source Type: research

An early analysis of Codman ® CerebroFlo® Endexo coated ventricular catheters in the setting of intraventricular hemorrhage
CONCLUSIONS: the CerebroFlo® catheter is a novel and effective tool in the management of IVH that should be widely considered for the management of IVH.PMID:34545731 | DOI:10.23736/S0390-5616.21.05421-7 (Source: Journal of Neurosurgical Sciences)
Source: Journal of Neurosurgical Sciences - September 21, 2021 Category: Neurosurgery Authors: Brian Fiani Ryan Jarrah Source Type: research

Brain low-grade gliomas with high-grade spinal localization. Report of a clinical case and systematic literature review
CONCLUSIONS: Spinal metastasis of intracranial LGGs is an adverse prognostic factor. Surgical violation of ventricles can play a role in the pathophysiology of CSF spread of tumor cells in LGGs.PMID:34545732 | DOI:10.23736/S0390-5616.21.05446-1 (Source: Journal of Neurosurgical Sciences)
Source: Journal of Neurosurgical Sciences - September 21, 2021 Category: Neurosurgery Authors: Francesca Battista Giovanni Muscas Silvia Scoccianti Anna Maria Buccoliero Davide Gadda Alessandro Della Puppa Source Type: research

Quantitative analysis of exposure and surgical maneuverability of three purely endoscopic keyhole approaches to the floor of the third ventricle
The objective of the study is to quantitatively assess and compare the exposure and microsurgical maneuverability of three absolutely endoscopic keyhole approaches, including interhemispheric transcallosal transchoroidal (TCTC), frontal transforminal transchoroidal (TFTC) and supraorbital subfrontal translamina terminalis (SFTL) approaches.METHODS: Anatomical dissections and exposure of the important structures of the third ventricle were performed using six formalin-fixed cadaveric human heads (twelve sides) under endoscope. Tubular retractor system was used in the TFTC approach. Quantitative anatomical relationship betwe...
Source: Journal of Neurosurgical Sciences - September 21, 2021 Category: Neurosurgery Authors: Changfu Zhang Zhengcun Yan Xiaodong Wang Yuping Li Hengzhu Zhang Source Type: research

Intraoperative MR Imaging in epilepsy surgery: systematic review of the literature and meta-analysis
CONCLUSIONS: This work presents the first meta-analysis of the value of iopMRI in epilepsy surgery. Its use resulted in an improvement of the desired extent of resection and led to a better seizure outcome compared to conventional surgery. Understanding its benefits might help improve surgical strategies in traditional, open epilepsy surgery.PMID:34545734 | DOI:10.23736/S0390-5616.21.05460-6 (Source: Journal of Neurosurgical Sciences)
Source: Journal of Neurosurgical Sciences - September 21, 2021 Category: Neurosurgery Authors: Matthias Tomschik Julia Shawarba Petra A Mercea Christian Dorfer Karl R össler Source Type: research

Artificial intelligence-enhanced intraoperative neurosurgical workflow: state of the art and future perspectives
CONCLUSIONS: In this review, we summarize the state-of-art applications of AI for the intraoperative augmentation of neurosurgical workflows across multiple subspecialties. ML models may boost surgical team performances by reducing human errors and providing patient-tailored surgical plans, but further and higher-quality studies need to be conducted.PMID:34545735 | DOI:10.23736/S0390-5616.21.05483-7 (Source: Journal of Neurosurgical Sciences)
Source: Journal of Neurosurgical Sciences - September 21, 2021 Category: Neurosurgery Authors: Leonardo Tariciotti Paolo Palmisciano Martina Giordano Giulia Remoli Eleonora Lacorte Giulio Bertani Marco Locatelli Francesco Dimeco Valerio M Caccavella Francesco Prada Source Type: research

Modafinil attenuates the neuroinflammatory response after experimental traumatic brain injury
This study aimed to explore if Modafinil can attenuate the neuroinflammatory phase of TBI and clarify the possible underlying mechanisms.METHODS: A weight drop model was used to induce experimental TBI on 30 Wistar albino rats. The treatment group received Modafinil on the day of the trauma and the following 5 days. Garcia Test was used to assess for neurological status and histopathological examination along with biochemical analysis of NSE, S-100B, CASP3, and TBARS levels were performed.RESULTS: Rats treated with Modafinil after the trauma had a statistically significant higher Garcia test score (p
Source: Journal of Neurosurgical Sciences - September 21, 2021 Category: Neurosurgery Authors: Yasar Ozturk Ismail Bozkurt Yahya Guvenc Umit Kepoglu Mehmet Cingirt Ozlem Gulbahar Tugba Ozcerezci Salim Senturk Mesut E Yaman Source Type: research

An early analysis of Codman ® CerebroFlo® Endexo coated ventricular catheters in the setting of intraventricular hemorrhage
CONCLUSIONS: the CerebroFlo® catheter is a novel and effective tool in the management of IVH that should be widely considered for the management of IVH.PMID:34545731 | DOI:10.23736/S0390-5616.21.05421-7 (Source: Journal of Neurosurgical Sciences)
Source: Journal of Neurosurgical Sciences - September 21, 2021 Category: Neurosurgery Authors: Brian Fiani Ryan Jarrah Source Type: research

Brain low-grade gliomas with high-grade spinal localization. Report of a clinical case and systematic literature review
CONCLUSIONS: Spinal metastasis of intracranial LGGs is an adverse prognostic factor. Surgical violation of ventricles can play a role in the pathophysiology of CSF spread of tumor cells in LGGs.PMID:34545732 | DOI:10.23736/S0390-5616.21.05446-1 (Source: Journal of Neurosurgical Sciences)
Source: Journal of Neurosurgical Sciences - September 21, 2021 Category: Neurosurgery Authors: Francesca Battista Giovanni Muscas Silvia Scoccianti Anna Maria Buccoliero Davide Gadda Alessandro Della Puppa Source Type: research

Quantitative analysis of exposure and surgical maneuverability of three purely endoscopic keyhole approaches to the floor of the third ventricle
The objective of the study is to quantitatively assess and compare the exposure and microsurgical maneuverability of three absolutely endoscopic keyhole approaches, including interhemispheric transcallosal transchoroidal (TCTC), frontal transforminal transchoroidal (TFTC) and supraorbital subfrontal translamina terminalis (SFTL) approaches.METHODS: Anatomical dissections and exposure of the important structures of the third ventricle were performed using six formalin-fixed cadaveric human heads (twelve sides) under endoscope. Tubular retractor system was used in the TFTC approach. Quantitative anatomical relationship betwe...
Source: Journal of Neurosurgical Sciences - September 21, 2021 Category: Neurosurgery Authors: Changfu Zhang Zhengcun Yan Xiaodong Wang Yuping Li Hengzhu Zhang Source Type: research

Intraoperative MR Imaging in epilepsy surgery: systematic review of the literature and meta-analysis
CONCLUSIONS: This work presents the first meta-analysis of the value of iopMRI in epilepsy surgery. Its use resulted in an improvement of the desired extent of resection and led to a better seizure outcome compared to conventional surgery. Understanding its benefits might help improve surgical strategies in traditional, open epilepsy surgery.PMID:34545734 | DOI:10.23736/S0390-5616.21.05460-6 (Source: Journal of Neurosurgical Sciences)
Source: Journal of Neurosurgical Sciences - September 21, 2021 Category: Neurosurgery Authors: Matthias Tomschik Julia Shawarba Petra A Mercea Christian Dorfer Karl R össler Source Type: research

Artificial intelligence-enhanced intraoperative neurosurgical workflow: state of the art and future perspectives
CONCLUSIONS: In this review, we summarize the state-of-art applications of AI for the intraoperative augmentation of neurosurgical workflows across multiple subspecialties. ML models may boost surgical team performances by reducing human errors and providing patient-tailored surgical plans, but further and higher-quality studies need to be conducted.PMID:34545735 | DOI:10.23736/S0390-5616.21.05483-7 (Source: Journal of Neurosurgical Sciences)
Source: Journal of Neurosurgical Sciences - September 21, 2021 Category: Neurosurgery Authors: Leonardo Tariciotti Paolo Palmisciano Martina Giordano Giulia Remoli Eleonora Lacorte Giulio Bertani Marco Locatelli Francesco Dimeco Valerio M Caccavella Francesco Prada Source Type: research

Modafinil attenuates the neuroinflammatory response after experimental traumatic brain injury
This study aimed to explore if Modafinil can attenuate the neuroinflammatory phase of TBI and clarify the possible underlying mechanisms.METHODS: A weight drop model was used to induce experimental TBI on 30 Wistar albino rats. The treatment group received Modafinil on the day of the trauma and the following 5 days. Garcia Test was used to assess for neurological status and histopathological examination along with biochemical analysis of NSE, S-100B, CASP3, and TBARS levels were performed.RESULTS: Rats treated with Modafinil after the trauma had a statistically significant higher Garcia test score (p
Source: Journal of Neurosurgical Sciences - September 21, 2021 Category: Neurosurgery Authors: Yasar Ozturk Ismail Bozkurt Yahya Guvenc Umit Kepoglu Mehmet Cingirt Ozlem Gulbahar Tugba Ozcerezci Salim Senturk Mesut E Yaman Source Type: research

An early analysis of Codman ® CerebroFlo® Endexo coated ventricular catheters in the setting of intraventricular hemorrhage
CONCLUSIONS: the CerebroFlo® catheter is a novel and effective tool in the management of IVH that should be widely considered for the management of IVH.PMID:34545731 | DOI:10.23736/S0390-5616.21.05421-7 (Source: Journal of Neurosurgical Sciences)
Source: Journal of Neurosurgical Sciences - September 21, 2021 Category: Neurosurgery Authors: Brian Fiani Ryan Jarrah Source Type: research

Brain low-grade gliomas with high-grade spinal localization. Report of a clinical case and systematic literature review
CONCLUSIONS: Spinal metastasis of intracranial LGGs is an adverse prognostic factor. Surgical violation of ventricles can play a role in the pathophysiology of CSF spread of tumor cells in LGGs.PMID:34545732 | DOI:10.23736/S0390-5616.21.05446-1 (Source: Journal of Neurosurgical Sciences)
Source: Journal of Neurosurgical Sciences - September 21, 2021 Category: Neurosurgery Authors: Francesca Battista Giovanni Muscas Silvia Scoccianti Anna Maria Buccoliero Davide Gadda Alessandro Della Puppa Source Type: research

Quantitative analysis of exposure and surgical maneuverability of three purely endoscopic keyhole approaches to the floor of the third ventricle
The objective of the study is to quantitatively assess and compare the exposure and microsurgical maneuverability of three absolutely endoscopic keyhole approaches, including interhemispheric transcallosal transchoroidal (TCTC), frontal transforminal transchoroidal (TFTC) and supraorbital subfrontal translamina terminalis (SFTL) approaches.METHODS: Anatomical dissections and exposure of the important structures of the third ventricle were performed using six formalin-fixed cadaveric human heads (twelve sides) under endoscope. Tubular retractor system was used in the TFTC approach. Quantitative anatomical relationship betwe...
Source: Journal of Neurosurgical Sciences - September 21, 2021 Category: Neurosurgery Authors: Changfu Zhang Zhengcun Yan Xiaodong Wang Yuping Li Hengzhu Zhang Source Type: research

Intraoperative MR Imaging in epilepsy surgery: systematic review of the literature and meta-analysis
CONCLUSIONS: This work presents the first meta-analysis of the value of iopMRI in epilepsy surgery. Its use resulted in an improvement of the desired extent of resection and led to a better seizure outcome compared to conventional surgery. Understanding its benefits might help improve surgical strategies in traditional, open epilepsy surgery.PMID:34545734 | DOI:10.23736/S0390-5616.21.05460-6 (Source: Journal of Neurosurgical Sciences)
Source: Journal of Neurosurgical Sciences - September 21, 2021 Category: Neurosurgery Authors: Matthias Tomschik Julia Shawarba Petra A Mercea Christian Dorfer Karl R össler Source Type: research

Artificial intelligence-enhanced intraoperative neurosurgical workflow: state of the art and future perspectives
CONCLUSIONS: In this review, we summarize the state-of-art applications of AI for the intraoperative augmentation of neurosurgical workflows across multiple subspecialties. ML models may boost surgical team performances by reducing human errors and providing patient-tailored surgical plans, but further and higher-quality studies need to be conducted.PMID:34545735 | DOI:10.23736/S0390-5616.21.05483-7 (Source: Journal of Neurosurgical Sciences)
Source: Journal of Neurosurgical Sciences - September 21, 2021 Category: Neurosurgery Authors: Leonardo Tariciotti Paolo Palmisciano Martina Giordano Giulia Remoli Eleonora Lacorte Giulio Bertani Marco Locatelli Francesco Dimeco Valerio M Caccavella Francesco Prada Source Type: research

Household income is associated with return to surgery following discectomy for far lateral disc herniation
CONCLUSIONS: These findings suggest that household income may predict reoperation following FLDH surgery. Additional research is warranted into the relationship between household income and adverse neurosurgical outcomes.PMID:34342189 | DOI:10.23736/S0390-5616.21.05246-2 (Source: Journal of Neurosurgical Sciences)
Source: Journal of Neurosurgical Sciences - August 3, 2021 Category: Neurosurgery Authors: Austin J Borja John Connolly Svetlana Kvint Donald K Detchou Gregory Glauser Krista Strouz Scott D McCLINTOCK Paul J Marcotte Neil R Malhotra Source Type: research

A supervised machine learning algorithm predicts intraoperative CSF leak in endoscopic transsphenoidal surgery for pituitary adenomas: model development and prospective validation
CONCLUSIONS: The RF classifier showed the best performance across all models selected. RF models might predict surgical outcomes in heterogeneous multimorbid and fragile populations outperforming classical statistical analyses and other ML models (SVM, ANN etc.), improving patient management and reducing preventable morbidity and additional costs.PMID:34342190 | DOI:10.23736/S0390-5616.21.05295-4 (Source: Journal of Neurosurgical Sciences)
Source: Journal of Neurosurgical Sciences - August 3, 2021 Category: Neurosurgery Authors: Leonardo Tariciotti Giorgio Fiore Giorgio Carrabba Giulio A Bertani Luigi Schisano Stefano Borsa Emanuele Ferrante Valerio M Caccavella Pierpaolo Mattogno Martina Giordano Giulia Remoli Giovanna Mantovani Marco Locatelli Source Type: research

Evidence-based medicine in neurosurgery: why and how?
J Neurosurg Sci. 2021 Aug 3. doi: 10.23736/S0390-5616.21.05331-5. Online ahead of print.ABSTRACTSince its inception, medical training and practice are based primarily on the clinical experience provided by the mentors of each of the medical schools. In the 1990s, the first steps were taken for the construction of what we now know as evidence-based medicine. Evidence-based medicine is the set of studies, methods, and principles for the prevention of medical diseases, management guidelines, and algorithms used in sources of evidence. Neurosurgery based on evidence has emerged thanks to advances in neuroscience and informatio...
Source: Journal of Neurosurgical Sciences - August 3, 2021 Category: Neurosurgery Authors: Cristian Blanco-Teher án Loraine Quintana-P ájaro Alexis Narvaez-Rojas Rafael Mart ínez-Pérez Ezequiel Garc ía-Ballestas Luis Moscote Salazar Silvia Prada-Soto Ivan Lozada-Mart ínez Source Type: research

The use of Mixed Reality for the treatment planning of unruptured intracranial aneurysms
CONCLUSIONS: We demonstrated that MR could play important role in planning the surgical treatment of intracranial aneurysms by enhancing the visualization and understanding of the patient-specific anatomy.PMID:34342192 | DOI:10.23736/S0390-5616.21.05356-X (Source: Journal of Neurosurgical Sciences)
Source: Journal of Neurosurgical Sciences - August 3, 2021 Category: Neurosurgery Authors: Vito Stifano Maria C Palumbo Swathi Chidambaram Carmelo L Sturiale Alessio Albanese Enrico Marchese Alberto Redaelli Susan C Pannullo Alessandro Olivi Source Type: research

Microsurgical clipping of Unruptured Intracranial Aneurysms (UIA) by a single surgeon's experience: why we should definitely preserve the neurosurgical skills in our health areas
CONCLUSIONS: According to our experience, we believe that microsurgical clipping plays a critical role in the management of UIA, also on the ground of the encouraging results of the relevant Literature.PMID:34342193 | DOI:10.23736/S0390-5616.21.05366-2 (Source: Journal of Neurosurgical Sciences)
Source: Journal of Neurosurgical Sciences - August 3, 2021 Category: Neurosurgery Authors: Biagia LA Pira Veronica Picotti Marta Zappal à Vincenza Maiola Alessandro Pesce Alessandro Frati Antonio Santoro Giancarlo D'Andrea Source Type: research

Intraventricular Masson tumor: case report and systematic review of primary intracranial intravascular papillary endothelial hyperplasia
We report the case of a 79-year-old woman who presented with confusion, gait instability, and urinary incontinence. Neuroimaging revealed a hemorrhagic lesion within the right lateral ventricle, which was successfully resected. To our knowledge, this is the first reported case of an intraventricular IPEH and 33rd case of primary intracranial IPEH. We further performed a systematic review of the literature on all prior type I intracranial IPEH cases and discuss the importance of long-term follow-up in intracranial IPEH.PMID:34342194 | DOI:10.23736/S0390-5616.21.05372-8 (Source: Journal of Neurosurgical Sciences)
Source: Journal of Neurosurgical Sciences - August 3, 2021 Category: Neurosurgery Authors: Branavan Manoranjan Jennifer A Mann Jeffrey T Joseph John J Kelly Source Type: research

The effect of modic changes on the fusion rates of posterior interbody fusion surgery modic changes and posterior interbody fusion
CONCLUSIONS: Modic changes were not observed to be directly correlated to the radiological outcomes of instrumented posterior interbody fusion. The fusion rate demonstrated homogenous distribution between the Modic groups and the subsidence rate was slightly higher in MC1 and MC2 than in MC3 and MC0.PMID:34342195 | DOI:10.23736/S0390-5616.21.05386-8 (Source: Journal of Neurosurgical Sciences)
Source: Journal of Neurosurgical Sciences - August 3, 2021 Category: Neurosurgery Authors: Samet Erin ç Mahmet A Talma ç Bahattin Kemah Mustafa H Özdemir Source Type: research

Are injectable regenerative therapies effective in the treatment of Degenerative Disc Disease? A systematic literature review
CONCLUSIONS: Degenerative disc disease is a major health concern. Regenerative therapies could play a role in the treatment of its symptoms, as they have been proven to be clinically effective, cheap, and safe. Nevertheless, further studies are needed, in order to establish evidence based standardized treatments.PMID:34342196 | DOI:10.23736/S0390-5616.21.05389-3 (Source: Journal of Neurosurgical Sciences)
Source: Journal of Neurosurgical Sciences - August 3, 2021 Category: Neurosurgery Authors: Alberto DI Martino Francesca Barile Michele Fiore Alberto Ruffilli Cesare Faldini Source Type: research

Meningoencephalitis with refractory intracranial hypertension : Consider Decompressive craniectomy
CONCLUSIONS: DC appears to be a promising therapeutic option in cases of ME with refractory ICH. Thus, reliable criteria will have to be defined to guide us in our practice in emergency cases where DC has not been part of the therapeutic arsenal yet.PMID:34342197 | DOI:10.23736/S0390-5616.21.05397-2 (Source: Journal of Neurosurgical Sciences)
Source: Journal of Neurosurgical Sciences - August 3, 2021 Category: Neurosurgery Authors: Anis Choucha Sebastien Boissonneau Nathan Beucler Thomas Graillon Stephane Ranque Nicolas Bruder Stephane Fuentes Lionel Velly Henry Dufour Source Type: research

Combined endoscopic endonasal and transorbital approach to skull base tumors: a systematic literature review
CONCLUSIONS: A combined endoscopic endonasal and transorbital multiportal approach grants an adequate corridor to access several skull base tumors, such as those extending towards the paramedian aspects, providing good outcomes in terms of extent of tumor resection with acceptable rates of complications. These preliminary results might encourage the use of multiportal approaches in selected complex skull base neoplasms.PMID:34342198 | DOI:10.23736/S0390-5616.21.05401-1 (Source: Journal of Neurosurgical Sciences)
Source: Journal of Neurosurgical Sciences - August 3, 2021 Category: Neurosurgery Authors: Alberto DI Somma Giulia Guizzardi Cl àudia Valls Cusiné Jhon Hoyos Abel Ferres Thomaz E Topczewski Alejandra Mosteiro Andrea DE Rosa Domenico Solari Luigi M Cavallo Luis Reyes Joaquim Ense ñat Source Type: research

Serum biomarkers for risk assessment of intra-hospital transports in neurosurgical intensive care unit patients
J Neurosurg Sci. 2021 Aug 3. doi: 10.23736/S0390-5616.21.05409-6. Online ahead of print.ABSTRACTBACKGROUND: Intra-hospital transport (IHT) of neurosurgical intensive care (NICU) patients for cranial computed tomography (CCT) scans is associated with a high rate of complications. The potential of serum biomarkers to estimate the risk for complications associated with IHT and improve their safety remains underexplored. The present study investigated the influence of several serum biomarkers on IHT-associated complications in brain-injured NICU patients.METHODS: A total of 523 IHTs in 223 NICU patients were prospectively anal...
Source: Journal of Neurosurgical Sciences - August 3, 2021 Category: Neurosurgery Authors: Michael Bender Jessica Utermarck Eberhard Uhl Marco Stein Source Type: research

The impact of strategies to manage the COVID-19 pandemic on patients with intrathecal baclofen therapy
CONCLUSIONS: Our survey showed that the adopted strategies provided a feeling of confidence and safety among ITB patients and their caregivers during the COVID-19 pandemic. We think that a clear communication is always of paramount importance to manage these patients.PMID:34342200 | DOI:10.23736/S0390-5616.21.05410-2 (Source: Journal of Neurosurgical Sciences)
Source: Journal of Neurosurgical Sciences - August 3, 2021 Category: Neurosurgery Authors: Manuela D'Ercole Alessandro Izzo Filomena Fuggetta Alessandro Rapisarda Benedetta Burattini Nicola Montano Source Type: research

Research career in neurosurgery: a challenge for future neurosurgeons
J Neurosurg Sci. 2021 Aug 3. doi: 10.23736/S0390-5616.21.05426-6. Online ahead of print.NO ABSTRACTPMID:34342201 | DOI:10.23736/S0390-5616.21.05426-6 (Source: Journal of Neurosurgical Sciences)
Source: Journal of Neurosurgical Sciences - August 3, 2021 Category: Neurosurgery Authors: Michael G Ortega-Sierra Valeria Prado-Grajales Rafael Martinez-Imbett Karina Un ás-Perea Ivan D Lozada Martinez Source Type: research

Epidemiology, diagnosis and management of Baastrup's diseases: a systematic review
CONCLUSIONS: Baastrup disease is a common cause of low back pain. Proper diagnosis needs for imaging investigations and dynamic flexion-extension radiographs. Conservative and surgical therapies are available but there is a need for randomized clinical trials.PMID:34342202 | DOI:10.23736/S0390-5616.21.05428-X (Source: Journal of Neurosurgical Sciences)
Source: Journal of Neurosurgical Sciences - August 3, 2021 Category: Neurosurgery Authors: Maria C Meluzio Amarildo Smakaj Andrea Perna Calogero Velluto Giovanni Grillo Luca Proietti Ivan DE Martino Francesco C Tamburrelli Source Type: research

Gliomagenesis is orchestrated by the Oct3/4 regulatory network
J Neurosurg Sci. 2021 Aug 3. doi: 10.23736/S0390-5616.21.05437-0. Online ahead of print.ABSTRACTGlioblastoma multiforme (GBM) is a lethal brain tumor characterized by developmental hierarchical phenotypic heterogeneity, therapy resistance and recurrent growth. Neural stem cells (NSCs) from human central nervous system (CNS), and glioblastoma stem cells from patient-derived GBM (pdGSC) samples and cultured in both 2D well-plate and 3D monoclonal neurosphere culture system (pdMNCS). The pdMNCS model shows promise to establish a relevant 3D-tumor environment that maintains GBM cells in the stem cell phase within suspended neu...
Source: Journal of Neurosurgical Sciences - August 3, 2021 Category: Neurosurgery Authors: Tatyana N Ignatova Hersh J Chaitin Nickolay V Kukekov Oleg N Suslov Galina I Dulatova Khalid A Hanafy Frank D Vrionis Source Type: research

Quantitative gait analysis of patients with severe sacroiliac joint dysfunction: a prospective clinical study
CONCLUSIONS: This paper is the first to perform complex quantitative gait analysis of patients with SIJ dysfunction and to compare it with healthy individuals. These results can provide clinicians with baseline gait values for these patients in order to objectively quantify the extent of their disease.PMID:34342204 | DOI:10.23736/S0390-5616.21.05448-5 (Source: Journal of Neurosurgical Sciences)
Source: Journal of Neurosurgical Sciences - August 3, 2021 Category: Neurosurgery Authors: Jan Lodin Marek Jel ínek Jan Proch ázka Martin Same š Petr Vachata Source Type: research

Does the extent of soft tissue dissection and location of screws in anterior cervical discectomy and fusion impact the development of the adjacent segment degeneration? A prospective short term radiological analysis
CONCLUSIONS: The minimal soft tissue dissection for single level ACDF with PEEK cage placement appears to have reducing rate of ASD compared to conventional ACDF. Minimal soft tissue dissection has better Postoperative VAS scores.PMID:34342205 | DOI:10.23736/S0390-5616.21.05458-8 (Source: Journal of Neurosurgical Sciences)
Source: Journal of Neurosurgical Sciences - August 3, 2021 Category: Neurosurgery Authors: Mudumba Vijayasaradhi Kode Sashanka Rajesh Alugolu Source Type: research

Merging prospective and retrospective validation studies for intracranial aneurysms risk scores: reflections in the water
J Neurosurg Sci. 2021 Aug 3. doi: 10.23736/S0390-5616.21.05481-3. Online ahead of print.NO ABSTRACTPMID:34342206 | DOI:10.23736/S0390-5616.21.05481-3 (Source: Journal of Neurosurgical Sciences)
Source: Journal of Neurosurgical Sciences - August 3, 2021 Category: Neurosurgery Authors: Carmelo L Sturiale Vittorio Stumpo Kristy Latour Vito Stifano Source Type: research

Social violence and neurosurgery: a third world country perspective
J Neurosurg Sci. 2021 Aug 3. doi: 10.23736/S0390-5616.21.05488-6. Online ahead of print.NO ABSTRACTPMID:34342207 | DOI:10.23736/S0390-5616.21.05488-6 (Source: Journal of Neurosurgical Sciences)
Source: Journal of Neurosurgical Sciences - August 3, 2021 Category: Neurosurgery Authors: Paola E Falla-Rivera Karla P D íaz-González Carlos A Acevedo-Gonzalez Isabella Rosillo Mar ía P Bolaño-Romero Source Type: research

Robotic neurosurgery and post-COVID 19 neurological syndrome: two colossal challenges for low- and middle-income countries
J Neurosurg Sci. 2021 Aug 3. doi: 10.23736/S0390-5616.21.05489-8. Online ahead of print.NO ABSTRACTPMID:34342208 | DOI:10.23736/S0390-5616.21.05489-8 (Source: Journal of Neurosurgical Sciences)
Source: Journal of Neurosurgical Sciences - August 3, 2021 Category: Neurosurgery Authors: Michael G Ortega-Sierra Osnaider A Cuello-Torres Alexander Jim énez-Arteaga Lina M P érez-Benitez Mar ía P Bolaño-Romero Source Type: research