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Nutrition: Vitamin B

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Total 34 results found since Jan 2013.

Early Detection of Subclinical Atherosclerosis: Hyperhomocysteinemia as a Promising Marker in Adolescents With Vitamin B Deficiency
Cureus. 2023 Jul 8;15(7):e41571. doi: 10.7759/cureus.41571. eCollection 2023 Jul.ABSTRACTIn recent decades, the increased incidence of cardiovascular disease (CVD) mortality among young adults has raised concerns. Although clinical manifestations of CVD typically occur later in life, the underlying pathological processes emerge early on. This review article summarizes the association between vitamin B deficiency-induced hyperhomocysteinemia and subclinical atherosclerosis in adolescents. Numerous studies have demonstrated that elevated homocysteine levels are an independent risk factor for endothelial dysfunction (ED) and ...
Source: Atherosclerosis - August 9, 2023 Category: Cardiology Authors: Parth S Shirode Anjali D Parekh Vishwa V Patel Janmay Vala Aniket M Jaimalani Nilofar M Vora Vaishnavi Gummalla Jaineel S Patel Nikitha Shriram Source Type: research

Effects of vitamin B < sub > 12 < /sub > deficiency on risk and outcome of ischemic stroke
Clin Biochem. 2023 May 27:110591. doi: 10.1016/j.clinbiochem.2023.110591. Online ahead of print.ABSTRACTIschemic stroke is the most prevalent form of stroke and has a high incidence in older adults, characterized by high morbidity, mortality, disability, and recurrence rate. Vitamin B12 deficiency is prevalent in the elderly and has been reported to be associated with ischemic stroke. The mechanisms maybe include the disorder of methylation metabolism, accumulation of toxic metabolites, immune dysfunction, affecting gut microbial composition and gut-brain immune homeostasis, and toxic stress responses to the brain. Vitamin...
Source: Clinical Biochemistry - May 29, 2023 Category: Biochemistry Authors: Li Zhou Xiaosong Song Jiani Wang Yongjun Tan Qin Yang Source Type: research

Hyperhomocysteinemia in cardiovascular diseases: revisiting observational studies and clinical trials
In conclusion, revisiting observational studies and clinical trials suggests that cardiovascular patients should be screened for hyperhomocysteinemia, when no other risk factor is found. Patients with intermediate/major hyperhomocysteinemia should be properly assessed and treated for vitamin B deficiencies and inherited disorders according to current guidelines. Further trials are needed to assess the lowering homocysteine effect according to hyperhomocysteinemia categories at baseline.PMID:36170884 | DOI:10.1055/a-1952-1946
Source: Thrombosis and Haemostasis - September 28, 2022 Category: Hematology Authors: Jean-Louis Gueant Rosa-Maria Gueant-Rodriguez Abderrahim Oussalah Stephane Zuily Irwin Rosenberg Source Type: research

The Controversial Role of HCY and Vitamin B Deficiency in Cardiovascular Diseases
Nutrients. 2022 Mar 28;14(7):1412. doi: 10.3390/nu14071412.ABSTRACTPlasma homocysteine (HCY) is an established risk factor for cardiovascular disease CVD and stroke. However, more than two decades of intensive research activities has failed to demonstrate that Hcy lowering through B-vitamin supplementation results in a reduction in CVD risk. Therefore, doubts about a causal involvement of hyperhomocysteinemia (HHcy) and B-vitamin deficiencies in atherosclerosis persist. Existing evidence indicates that HHcy increases oxidative stress, causes endoplasmatic reticulum (ER) stress, alters DNA methylation and, thus, modulates t...
Source: Atherosclerosis - April 12, 2022 Category: Cardiology Authors: Wolfgang Herrmann Markus Herrmann Source Type: research

Genetics of hyperhomocysteinemia and 1-carbon metabolism: implications for retinal structure and eye functions.
Abstract Homocysteine (Hcy); a sulfur-containing non-proteinogenic amino acid is generated as a metabolic intermediate. Hcy constitutes an important part of the "1-carbon metabolism" during methionine turnover. Elevated levels of Hcy known as hyperhomocysteinemia (HHcy) results from vitamin B deficiency, lack of exercise, smoking, excessive alcohol intake, high fat and methionine rich diet, and the underlying genetic defects. These factors directly affect the "1-carbon metabolism (methionine-Hcy-folate)" of a given cell. In fact, the Hcy levels are determined primarily by dietary intake, vitamin status, and the ge...
Source: Canadian Journal of Physiology and Pharmacology - July 31, 2019 Category: Drugs & Pharmacology Authors: George AK, Majumder A, Ice H, Homme RP, Eyob W, Tyagi SC, Singh M Tags: Can J Physiol Pharmacol Source Type: research

The Rest of the Story on Vitamin B for Stroke Prevention
(MedPage Today) -- J. David Spence, MD, digs into the developing rationale for a different kind of B
Source: MedPage Today Nephrology - October 17, 2018 Category: Urology & Nephrology Source Type: news

The PAr index, an indicator reflecting altered vitamin B-6 homeostasis, is associated with long-term risk of stroke in the general population: the Hordaland Health Study (HUSK)
ConclusionsHigher plasma PAr was independently associated with increased risk of incident stroke in all participants and across all subgroups stratified by conventional risk predictors. Our novel findings point to and expand the range of inflammation and immune activation processes that may be relevant for the pathogenesis and prevention of stroke. This trial was registered at clinicaltrials.gov as NCT03013725.
Source: American Journal of Clinical Nutrition - January 26, 2018 Category: Nutrition Source Type: research

The PAr index, an indicator reflecting altered vitamin B-6 homeostasis, is associated with long-term risk of stroke in the general population: the Hordaland Health Study (HUSK).
Conclusions: Higher plasma PAr was independently associated with increased risk of incident stroke in all participants and across all subgroups stratified by conventional risk predictors. Our novel findings point to and expand the range of inflammation and immune activation processes that may be relevant for the pathogenesis and prevention of stroke. This trial was registered at clinicaltrials.gov as NCT03013725. PMID: 29381795 [PubMed - in process]
Source: The American Journal of Clinical Nutrition - January 1, 2018 Category: Nutrition Authors: Zuo H, Tell GS, Ueland PM, Nygård O, Vollset SE, Midttun Ø, Meyer K, Ulvik A Tags: Am J Clin Nutr Source Type: research

Clinical study on anti-epileptic drug with B vitamins for the treatment of epilepsy after stroke.
CONCLUSIONS: Anti-epilepsy drugs combined with B vitamins can improve epilepsy control after stroke and reduce new stroke occurrence. This effect may be associated with stability of plasma ADMA levels. Vitamin B12 may be better than vitamin B complex in the treatment of epilepsy after stroke. PMID: 28770947 [PubMed - in process]
Source: European Review for Medical and Pharmacological Sciences - August 6, 2017 Category: Drugs & Pharmacology Tags: Eur Rev Med Pharmacol Sci Source Type: research

Relation between vitamin B12 and SYNTAX Score.
CONCLUSION: In our study, we found significant relationship between vitamin B12 deficiency and SYNTAX score demonstrating the severity and complexity of coronary artery disease. PMID: 27391912 [PubMed - as supplied by publisher]
Source: Polish Heart Journal - July 7, 2016 Category: Cardiology Authors: Cerit L, Duygu H, Gulsen K, Kemal H, Tosun O, Ozcem B, Cerit Z, Gunsel A Tags: Kardiol Pol Source Type: research

Folate and MMA Predict Cognitive Impairment in Elderly Stroke Survivors: A Cross Sectional Study
Elderly stroke survivors are at risk of malnutrition and long-term cognitive impairment. Vitamin B-related metabolites, folate and methylmalonic acid, have been implicated in cognitive function. We conducted a study exploring the relationship between blood folate, methylmalonic acid and post-stroke cognitive impairment. This is a cross sectional study of elderly Swedish patients (n = 149) 20 months post-stroke, assessed using the Mini Mental State Examination, serum blood levels of methylmalonic acid and red blood cell levels of folate.
Source: Psychiatry Research - June 14, 2016 Category: Psychiatry Authors: Michaela C. Pascoe, Thomas Linden Source Type: research

Help! My daughter has become a vegetarian!
Q: My daughter has decided to follow a vegetarian diet. Do I need to worry about protein deficiency? ~ Worried Mom This is one of the most common questions that pediatricians are asked. A vegetarian diet, and especially one that includes fish, can be a very healthy option. Learn more about nutrition for vegetarians and ways your family can shift to a vegetarian diet. Q: Does my child need to eat meat to get enough protein? Complete nutrition, including adequate protein, can easily be obtained without eating meat. Meat is completely unnecessary if a diet is high in fruits, vegetables, nuts, beans, fish, whole grains, eggs...
Source: Thrive, Children's Hospital Boston - April 6, 2016 Category: Pediatrics Authors: Carolyn Sax Tags: Parenting Teen Health Dr. Carolyn Sax vegetarian Source Type: news